Internal Medicine
Review: Opioids and falls risk in older adults.
4 May, 2022 | 10:27h | UTCOpioids and Falls Risk in Older Adults: A Narrative Review – Drugs & Aging
Cohort Study: Characterizing older adults’ risk of harm from blood-pressure lowering medications.
4 May, 2022 | 10:26h | UTC
Cohort study: frailty is significantly associated with medication-related harm.
4 May, 2022 | 08:17h | UTC
Remdesivir and three other drugs for hospitalized patients with COVID-19: final results of the WHO Solidarity randomized trial and updated meta-analyses.
3 May, 2022 | 11:18h | UTCInvited Commentary: When and which patients should receive remdesivir? – The Lancet
RCT: Effects of an online breathing and wellbeing program for people with persistent symptoms following COVID-19.
3 May, 2022 | 11:16h | UTCInvited Commentary: Treating COVID-19-related breathlessness with novel interventions – The Lancet Respiratory Medicine
News Release: Singing techniques can improve quality of life and breathlessness after COVID-19 – Imperial College London
Commentary on Twitter
https://twitter.com/LancetRespirMed/status/1519572126772064256
Systematic Review: Telerehabilitation improves physical function and reduces dyspnea in people with COVID-19 and post-COVID-19 conditions.
3 May, 2022 | 11:05h | UTC
Point/Counterpoint: Should therapeutic heparin be administered to acutely ill hospitalized patients with COVID-19?
3 May, 2022 | 11:04h | UTCCOUNTERPOINT: Should Therapeutic Heparin Be Administered to Acutely Ill Hospitalized Patients With COVID-19? No – CHEST
See also: Rebuttal From Dr Tritschler et al – CHEST
Related:
Anticoagulants for people hospitalised with COVID‐19 – Cochrane Library
M-A of randomized trials: association of influenza vaccination with cardiovascular risk.
3 May, 2022 | 10:58h | UTCAssociation of Influenza Vaccination With Cardiovascular Risk: A Meta-analysis – JAMA Network Open
Commentary on Twitter
In this meta-analysis, seasonal flu vaccine was associated with a 34% reduced risk of major adverse cardiovascular events in 1 year, with the biggest difference in patients with recent acute coronary syndrome. @WCHResearch @PMunkCardiacCtr https://t.co/SPrXNfMQJS
— JAMA Network Open (@JAMANetworkOpen) April 29, 2022
CDC reports the first case and issues recommendations for highly pathogenic avian Influenza A(H5N1) virus.
3 May, 2022 | 11:00h | UTCSee also: U.S. Case of Human Avian Influenza A(H5) Virus Reported – Centers for Disease Control and Prevention
Commentary: Alaska, Oklahoma report first avian flu outbreaks in poultry – CIDRAP
Perspective: Less pharmacotherapy is more in delirium.
3 May, 2022 | 10:56h | UTCLess pharmacotherapy is more in delirium – Intensive Care Medicine (if the link is paywalled, try this one)
Related:
Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine
Commentary on Twitter
⬇️ 💉Less medications (& ⬆️ awareness of behavioural interventions) is more in #delirium, common, challenging/costly (but often preventable) in #ICU. Despite lacking evidence, medications widely used.
Prevent/minimize addressing suspected contributors!
📎 https://t.co/fYWAsIcuiZ pic.twitter.com/DyC3agSP7w— Intensive Care Medicine (@yourICM) April 30, 2022
Review | Glycemic control in the critically ill: Less is more.
3 May, 2022 | 10:50h | UTCGlycemic control in the critically ill: Less is more – Cleveland Clinic Journal of Medicine
Editorial: Glycemic targets in the ICU: A look back, and ahead – Cleveland Clinic Journal of Medicine
Cohort Study: Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism.
3 May, 2022 | 10:41h | UTC
Commentary on Twitter
Chronic thromboembolic pulmonary hypertension and impairment after pulmonary embolism: the FOCUS study https://t.co/IOvHAzKwa2 #EHJ #ESCYoung @ehj_ed @rladeiraslopes pic.twitter.com/ADFp09rooI
— European Society of Cardiology Journals (@ESC_Journals) May 2, 2022
Contemporary antiplatelet therapy for secondary stroke prevention: a narrative review of current literature and guidelines.
3 May, 2022 | 10:26h | UTC
ATS/ERS/JRS/ALAT Guideline: Idiopathic pulmonary fibrosis and progressive pulmonary fibrosis in adults.
2 May, 2022 | 00:53h | UTC
Commentary on Twitter (thread – click for more)
🔥Finally out online: the latest multisocietal guidance defining progression in fibrotic lung disease🫁 has arrived!
These long-awaited guidelines help better clarify disease definition and guide treatmenthttps://t.co/LVuoVdZRj2
What does this mean? Hang on to your hats! 🧵1/n pic.twitter.com/3jvFGSfSuI
— Deji Adegunsoye, MD, PhD (@drdayjee) April 29, 2022
Pfizer says COVID treatment Paxlovid fails to prevent infection of household members.
2 May, 2022 | 00:43h | UTCPfizer says COVID treatment Paxlovid fails to prevent infection of household members – Reuters
Commentary on Twitter
Pfizer Inc on Friday said a large trial found that its COVID-19 oral antiviral treatment Paxlovid was not effective at preventing coronavirus infection in people living with someone who had been exposed to the virus. https://t.co/95zphEYaxc
— Reuters Health (@Reuters_Health) April 29, 2022
Consensus Recommendations: Quality standards for the management of non-alcoholic fatty liver disease.
2 May, 2022 | 00:21h | UTCRelated Guidelines:
Non-alcoholic fatty liver disease: A patient guideline – JHEP Reports
NICE chronic primary pain guidelines: what the busy GP needs to know.
2 May, 2022 | 00:25h | UTCOriginal Guideline: Chronic pain (primary and secondary) in over 16s: assessment of all chronic pain and management of chronic primary pain – National Institute for Health and Care Excellence
Guideline: Management of alcohol-related liver disease.
1 May, 2022 | 23:34h | UTC
10-year results of a RCT: Effects of parathyroidectomy vs. observation on morbidity and mortality in patients with mild primary hyperparathyroidism.
1 May, 2022 | 23:22h | UTCMortality and Morbidity in Mild Primary Hyperparathyroidism: Results From a 10-Year Prospective Randomized Controlled Trial of Parathyroidectomy Versus Observation – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Parathyroidectomy No Better for Mild Primary Hyperparathyroidism – HealthDay
Commentary on Twitter
#ICYMI: new RCT from @UniOslo found early surgery does not appear to reduce negative outcomes for healthy patients with primary #hyperparathyroidism: https://t.co/RnWadklja2 pic.twitter.com/vuS4xSt128
— Annals of Int Med (@AnnalsofIM) April 25, 2022
Review: Anti-tuberculosis treatment strategies and drug development: challenges and priorities.
1 May, 2022 | 23:23h | UTCAnti-tuberculosis treatment strategies and drug development: challenges and priorities – Nature Reviews Microbiology (if the link is paywalled, try this one)
News Release: A major update on global tuberculosis fight – Hackensack Meridian Health
Commentary on Twitter
Anti-tuberculosis treatment strategies and drug development: challenges and prioritieshttps://t.co/nZlcEwTDLP
In this Review, Dartois and Rubin explore challenges and priorities for anti-tuberculosis treatment strategies and drug development.@vdartois1 pic.twitter.com/t6RQoaFb8C
— Nature Reviews Microbiology (@NatureRevMicro) April 27, 2022
M-A: Comparative safety and efficacy of cognitive enhancers for Alzheimer’s dementia.
1 May, 2022 | 23:10h | UTC
M-A: The effect of endogenous Cushing’s syndrome on all-cause and cause-specific mortality.
1 May, 2022 | 23:05h | UTC
Checklists to reduce diagnostic error: a systematic review of the literature using a human factors framework.
1 May, 2022 | 23:02h | UTC
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.
29 Apr, 2022 | 10:51h | UTC
Commentary on Twitter
🆕💥Review Article @ASHE_Journal
Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them #IDTwitter #medtwitter #TwitteRx #MedEd https://t.co/ToPLQXtC4r pic.twitter.com/pZQWWb3ZSx— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 28, 2022
Under a http://creativecommons.org/licenses/by/4.0/ license
Varicose veins: what can be done to help?
29 Apr, 2022 | 10:49h | UTCVaricose veins: what can be done to help? – Evidently Cochrane
Related:
Interventions for great saphenous vein incompetence – Cochrane Library
Surgery for deep venous insufficiency – Cochrane Library
CHIVA method for the treatment of chronic venous insufficiency – Cochrane Library
Injection sclerotherapy for varicose veins – Cochrane Library