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Internal Medicine

Systematic Review: Outpatient versus inpatient treatment for acute pulmonary embolism.

9 May, 2022 | 01:47h | UTC

Outpatient versus inpatient treatment for acute pulmonary embolism – Cochrane Library

Commentary: Is home or hospital treatment better for people with blood clots in the lungs? – Cochrane Library

 

Commentary on Twitter

 


Clinical challenges treating Stenotrophomonas maltophilia infections: an update.

9 May, 2022 | 01:32h | UTC

Clinical challenges treating Stenotrophomonas maltophilia infections: an update – JAC-Antimicrobial Resistance

Related:

Overcoming Stenotrophomonas maltophilia Resistance for a More Rational Therapeutic Approach – Open Forum Infectious Diseases

Risk Factors for Acquired Stenotrophomonas maltophilia Pneumonia in Intensive Care Unit: A Systematic Review and Meta-Analysis – Frontiers in Medicine

Trimethoprim-Sulfamethoxazole versus Levofloxacin for Stenotrophomonas maltophilia Infections: A Retrospective Comparative Effectiveness Study of Electronic Health Records from 154 U.S. Hospitals – Open Forum Infectious Diseases

Infectious Diseases Society of America Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections – Clinical Infectious Diseases

 


RCT: Effect of early vs. standard approach to tracheostomy on functional outcome at 6 months among patients with severe stroke receiving mechanical ventilation.

6 May, 2022 | 11:13h | UTC

Effect of Early vs Standard Approach to Tracheostomy on Functional Outcome at 6 Months Among Patients With Severe Stroke Receiving Mechanical Ventilation: The SETPOINT2 Randomized Clinical Trial – JAMA (free for a limited period)

 

Commentary on Twitter

 


RCT: Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet.

6 May, 2022 | 11:05h | UTC

Long-term secondary prevention of cardiovascular disease with a Mediterranean diet and a low-fat diet (CORDIOPREV): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

 


Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomized controlled trials and cohort studies.

6 May, 2022 | 10:59h | UTC

Safety of ezetimibe in lipid-lowering treatment: systematic review and meta-analysis of randomised controlled trials and cohort studies – BMJ Medicine

Related:

PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations – The BMJ

PCSK9 inhibitors and ezetimibe with or without statin therapy for cardiovascular risk reduction: a systematic review and network meta-analysis – The BMJ

 

Commentary on Twitter

 


Long COVID: aiming for a consensus.

6 May, 2022 | 11:03h | UTC

Long COVID: aiming for a consensus – The Lancet Respiratory Medicine

 

Commentary on Twitter

 


Position statement on acute oxygen use in adults: ‘swimming between the flags’.

6 May, 2022 | 10:56h | UTC

Thoracic Society of Australia and New Zealand Position Statement on Acute Oxygen Use in Adults: ‘Swimming between the flags’ – Respirology

Related:

Long-term mortality and health-related quality of life of lower versus higher oxygenation targets in ICU patients with severe hypoxaemia – Intensive Care Medicine

Oxygen Targets During Mechanical Ventilation in the ICU: A Systematic Review and Meta-Analysis – Critical Care Explorations

Effect of Low-Normal vs High-Normal Oxygenation Targets on Organ Dysfunction in Critically Ill Patients: A Randomized Clinical Trial – JAMA

Lower or Higher Oxygenation Targets for Acute Hypoxemic Respiratory Failure – New England Journal of Medicine

 


Guideline Summary: New guidance on the perioperative management of diabetes.

6 May, 2022 | 10:55h | UTC

New guidance on the perioperative management of diabetes – Clinical Medicine Journal

Original Guideline: Perioperative Care of People with Diabetes Undergoing Surgery

Related:

Perioperative Evaluation and Management of Endocrine Disorders – Mayo Clinic Proceedings

Recent advances in diabetes treatments and their perioperative implications – Current Opinion in Anesthesiology

Perioperative Management of Oral Glucose-lowering Drugs in the Patient with Type 2 Diabetes – Anesthesiology

 


Systematic Review: Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression.

6 May, 2022 | 10:37h | UTC

Clinical practice guideline recommendations on tapering and discontinuing antidepressants for depression: a systematic review – Therapeutic Advances in Psychopharmacology

Related:

Discontinuing antidepressants: Pearls and pitfalls.

Review | Newer generation antidepressants and withdrawal effects: reconsidering the role of antidepressants and helping patients to stop.

RCT: Maintenance vs. discontinuation of antidepressants in patients who felt well enough to discontinue antidepressant therapy.

A method for tapering antipsychotic treatment that may minimize the risk of relapse

Systematic Review: Managing Antidepressant Discontinuation

Randomized controlled trial: preventive cognitive therapy for prevention of depressive recurrence

M-A: Continuation of antidepressants vs. sequential psychological interventions to prevent relapse in depression.

 


Review: Non-invasive testing and surrogate markers in invasive fungal diseases.

6 May, 2022 | 10:29h | UTC

Non-invasive Testing and Surrogate Markers in Invasive Fungal Diseases – Open Forum Infectious Diseases

 


Perspective | Does glycemic index matter for weight loss and obesity prevention? Examination of the evidence on “fast” compared with “slow” carbs.

6 May, 2022 | 10:19h | UTC

Perspective: Does Glycemic Index Matter for Weight Loss and Obesity Prevention? Examination of the Evidence on “Fast” Compared with “Slow” Carbs – Advances in Nutrition

 


PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations.

5 May, 2022 | 11:06h | UTC

PCSK9 inhibitors and ezetimibe for the reduction of cardiovascular events: a clinical practice guideline with risk-stratified recommendations – The BMJ

See also: PCSK9 inhibitors and ezetimibe with or without statin therapy for cardiovascular risk reduction: a systematic review and network meta-analysis – The BMJ

News Release: Experts recommend additional cholesterol lowering drugs for adults at high heart disease risk – British Medical Journal

 


2022 HRS expert consensus statement on evaluation and management of arrhythmic risk in neuromuscular disorders.

5 May, 2022 | 10:22h | UTC

2022 HRS expert consensus statement on evaluation and management of arrhythmic risk in neuromuscular disorders – Heart Rhythm

 


Review: Mental stress and its effects on vascular health.

5 May, 2022 | 10:28h | UTC

Mental Stress and Its Effects on Vascular Health – Mayo Clinic Proceedings

Related:

Association of the 2020 US Presidential Election With Hospitalizations for Acute Cardiovascular Conditions – JAMA Network Open

Psychological Stress and Heart Disease: Fact or Folklore? – The American Journal of Medicine

Sudden Cardiac Death Triggered by an Earthquake – New England Journal of Medicine

Cardiovascular Events during World Cup Soccer – New England Journal of Medicine

 


An expert panel Delphi consensus statement on the use of palliative care in the management of patients with pulmonary arterial hypertension.

5 May, 2022 | 10:17h | UTC

An expert panel Delphi consensus statement on the use of palliative care in the management of patients with pulmonary arterial hypertension – Pulmonary Circulation

 


Guideline: Management of hypertension in patients with diabetic kidney disease.

5 May, 2022 | 10:18h | UTC

Management of Hypertension in Patients With Diabetic Kidney Disease: Summary of the Joint Association of British Clinical Diabetologists and UK Kidney Association (ABCD-UKKA) Guideline 2021 – Kidney International Reports

 


Systematic Review: Immunosuppressive treatment for focal segmental glomerulosclerosis in adults.

5 May, 2022 | 10:03h | UTC

Summary: Immunosuppressive treatment for focal segmental glomerulosclerosis in adults – Cochrane Library

Original Study: Interventions for focal segmental glomerulosclerosis in adults – Cochrane Library

 


Management of patients presenting to the emergency department with sudden onset severe headache: systematic review of diagnostic accuracy studies.

5 May, 2022 | 10:08h | UTC

Management of patients presenting to the emergency department with sudden onset severe headache: systematic review of diagnostic accuracy studies – Emergency Medicine Journal

 


WHO calls for shorter drug course for resistant TB.

4 May, 2022 | 11:08h | UTC

WHO calls for shorter drug course for resistant TB – CIDRAP

Rapid communication: Key changes to the treatment of drug-resistant tuberculosis – World Health Organization

 


Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management.

4 May, 2022 | 11:02h | UTC

Heart failure with preserved ejection fraction: recent concepts in diagnosis, mechanisms and management – Heart

Podcast: A comprehensive review on heart failure with preserved ejection fraction (HFpEF)

 


Paxlovid’s failure as a preventative measure raises questions, but doctors still back it as a therapeutic.

4 May, 2022 | 10:57h | UTC

Paxlovid’s failure as a preventative measure raises questions, but doctors still back it as a therapeutic – STAT

 


Cluster RCT: Algorithm-based care vs. usual care for the early recognition and management of complications after pancreatic resection.

4 May, 2022 | 10:55h | UTC

Algorithm-based care versus usual care for the early recognition and management of complications after pancreatic resection in the Netherlands: an open-label, nationwide, stepped-wedge cluster-randomised trial – The Lancet (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Obesity causes cancer and is major determinant of disability and death, warns new WHO report.

4 May, 2022 | 10:49h | UTC

News Release: Obesity causes cancer and is major determinant of disability and death, warns new WHO report – WHO Europe

Report: WHO European Regional Obesity Report 2022 – World Health Organization

Commentary: ‘Epidemic’ of Obesity in Europe – Health Policy Watch

 

Commentary on Twitter

 


Review: Diagnosis and management of lumbar spinal stenosis.

4 May, 2022 | 10:45h | UTC

Diagnosis and Management of Lumbar Spinal Stenosis: A Review – JAMA (free for a limited period)

Audio Clinical Review: Lumbar Spinal Stenosis: A Review – JAMA

 


Review: Diagnostic management of pregnant women with suspected pulmonary embolism.

4 May, 2022 | 10:28h | UTC

Diagnostic Management of Pregnant Women With Suspected Pulmonary Embolism – Frontiers in Cardiovascular Medicine

 


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