Internal Medicine
M-A: Glucagon-like peptide-1 (GLP-1) receptor agonists and cardiovascular events in patients with type 2 diabetes mellitus.
18 May, 2022 | 10:53h | UTC
Commentary on Twitter
https://twitter.com/kamleshkhunti/status/1526474237481041921
Under a http://creativecommons.org/licenses/by/4.0/ license
Review: Management strategies in heart failure with preserved ejection fraction.
18 May, 2022 | 10:50h | UTCManagement strategies in heart failure with preserved ejection fraction – Herz
Review: Role of direct oral anticoagulants for post-operative venous thromboembolism prophylaxis.
18 May, 2022 | 10:46h | UTC
Commentary on Twitter
Our work on this review summarises the pharmacological profile of DOACs and highlights the use of #DOACs in post-operative #VTE prophylaxis based on the available clinical trialhttps://t.co/7MRvWBfaEG @radcliffeCARDIO @mmamas1973 @AnastasiaSMihai @mirvatalasnag @KardiologieHH pic.twitter.com/MW6n2CWGe0
— Henry Han (@HanCardiomd) May 13, 2022
Under a CC-BY-NC 4.0 license
Cohort Study: Rapid exclusion of acute myocardial injury and infarction with a single high sensitivity cardiac troponin T in the emergency department.
18 May, 2022 | 10:41h | UTCRapid Exclusion of Acute Myocardial Injury and Infarction with a Single High Sensitivity Cardiac Troponin T in the Emergency Department: a Multicenter United States Evaluation – Circulation (link to abstract – $ for full-text)
Commentary: Higher Single-Sample hs-cTnT Threshold Can Safely Exclude MI – TCTMD
Cohort Study: E-cigarette use and risk of cardiovascular disease.
18 May, 2022 | 10:40h | UTCCommentaries:
If You Smoke, Adding in E-Cigs Likely Won’t Cut CV Risks – TCTMD
CVD Risk Not Reduced With Dual Use of E-Cigarettes, Smoking – HealthDay
M-A: Tirzepatide cardiovascular event risk assessment.
18 May, 2022 | 10:34h | UTCTirzepatide cardiovascular event risk assessment: a pre-specified meta-analysis – Nature Medicine
Commentary: Meta-analysis backs tirzepatide CV safety – medwireNews
Commentary on Twitter
https://twitter.com/NatureMedicine/status/1497179669476614150
Guideline Synopsis: Antithrombotic therapy for venous thromboembolism.
17 May, 2022 | 11:12h | UTCAntithrombotic Therapy for Venous Thromboembolism – JAMA (free for a limited period)
Original Guideline: Antithrombotic Therapy for VTE Disease
Second Update of the CHEST Guideline and Expert Panel Report
Clinical update on COVID-19 for the emergency clinician: Cardiac arrest in the out-of-hospital and in-hospital settings.
17 May, 2022 | 11:05h | UTCRelated:
Cohort Study: Venous or arterial thrombosis and deaths among COVID-19 cases.
17 May, 2022 | 11:02h | UTCInvited Commentary: Risk of arterial and venous thromboses after COVID-19 – The Lancet Infectious Diseases
News Release: COVID-19’s high blood clot risk – University of Oxford
Commentary on Twitter
Clots with Covid: Multi-national report of over 900,000 people indicates propensity of risk for arterial and venous thrombi is in men, with increasing age, and association with fatalities (4-fold in non-hospitalized) https://t.co/muGnDld4Um pic.twitter.com/6bLiHPLInm
— Eric Topol (@EricTopol) May 13, 2022
Under a Creative Commons Attribution (CC BY 4.0) license
RECOVERY Trial: Due to safety concerns, recruitment to higher dose corticosteroids closed for patients with hypoxia on no oxygen or receiving simple oxygen.
17 May, 2022 | 11:04h | UTC
Strong, steady and straight: UK consensus statement on physical activity and exercise for osteoporosis.
17 May, 2022 | 10:56h | UTC
Cohort Study: The risk of death or unplanned readmission after discharge from a COVID-19 hospitalization.
17 May, 2022 | 11:01h | UTCCommentary: Study: Readmission rate for COVID-19 is 11% – CIDRAP
Evidence of a vegan diet for health benefits and risks – an umbrella review of meta-analyses of observational and clinical studies.
17 May, 2022 | 10:45h | UTC
Cohort Study: Sustainability of a clinical decision support intervention for outpatient care for emergency department patients with acute pulmonary embolism.
17 May, 2022 | 10:44h | UTCRelated: Outpatient versus inpatient treatment for acute pulmonary embolism – Cochrane Library
Commentary on Twitter
This multicenter cohort study of ED patients with acute pulmonary embolism found the initial increase in outpatient management from a physician champion-led, EHR-embedded clinical decision support intervention was sustained 4 years later. https://t.co/UPf8pAOTry
— JAMA Network Open (@JAMANetworkOpen) May 16, 2022
Alcohol withdrawal syndrome: identification and management.
17 May, 2022 | 10:37h | UTCAlcohol Withdrawal Syndrome: Identification and Management – emDocs
Podcast: Generalized anxiety disorder pearls.
17 May, 2022 | 10:35h | UTC#335 Generalized Anxiety Disorder – The Curbsiders
Review: Sodium Glucose Cotransporter-2 Inhibition for acute myocardial infarction.
17 May, 2022 | 10:32h | UTC
M-A: Dose-dependent effect of carbohydrate restriction for type 2 diabetes management.
17 May, 2022 | 10:30h | UTCDose-dependent effect of carbohydrate restriction for type 2 diabetes management: a systematic review and dose-response meta-analysis of randomized controlled trials – American Journal of Clinical Nutrition (link to abstract – $ for full-text)
Commentary on Twitter
#LowCarb: Carbohydrate restriction exerts a significant & important reduction on levels of cardiometabolic risk factors in patients with type 2 diabetes. Levels of most cardiometabolic outcomes decreased linearly with the decrease in carbohydrate intake. https://t.co/L8zwbsiTyn
— Nicolai Worm (@NicolaiWorm) May 15, 2022
Retrospective Cohort Study: Association of race and ethnicity with incidence of dementia among older adults.
17 May, 2022 | 10:29h | UTCAssociation of Race and Ethnicity With Incidence of Dementia Among Older Adults – JAMA (link to abstract – $ for full-text)
News Release: Cross-racial study of 1.87m vets shows wide disparities in dementia – University of California – San Francisco
Commentaries:
Significant Differences in Dementia Incidence Based on Race and Ethnicity – NeurologyToday
Strong evidence for differences in dementia risk by race and ethnicity – MedicalResearch
Dementia Incidence Varies by Race, Ethnicity – HealthDay
Commentary on Twitter
In this retrospective cohort study, among adults who received care at Veterans Health Administration medical centers, significant differences in #dementia incidence existed based on race and ethnicity. https://t.co/WguRziHyMa
— JAMA (@JAMA_current) April 25, 2022
M-A: Prevalence and methods for assessment of oropharyngeal dysphagia in older adults.
17 May, 2022 | 10:21h | UTC
RCT: Albuterol–budesonide fixed-dose combination rescue inhaler for asthma.
16 May, 2022 | 02:33h | UTCAlbuterol–Budesonide Fixed-Dose Combination Rescue Inhaler for Asthma – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
The risk of severe asthma exacerbation was significantly lower with as-needed use of a fixed-dose combination of 180 μg of albuterol and 160 μg of budesonide than with albuterol alone. #ATS2022 https://t.co/MRGaUaGVwj pic.twitter.com/6BZX9Q6WxX
— NEJM (@NEJM) May 15, 2022
RCT: Effect of awake prone positioning on endotracheal intubation in patients with COVID-19 and acute respiratory failure.
16 May, 2022 | 02:37h | UTCRelated:
RCT: Prone positioning of patients with moderate hypoxia due to COVID-19 – medRxiv
Commentary on Twitter
In this trial, in patients with acute hypoxemic respiratory failure from #COVID19, prone positioning, compared with usual care without prone positioning, did not significantly reduce endotracheal intubation at 30 days. https://t.co/1RyYRtcrYj
— JAMA (@JAMA_current) May 15, 2022
Trial of a preferential Phosphodiesterase 4B Inhibitor for idiopathic pulmonary fibrosis.
16 May, 2022 | 02:32h | UTCTrial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/NEJM/status/1525878684380430343
RCT: Comparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults.
16 May, 2022 | 02:30h | UTCComparison of 8 versus 15 days of antibiotic therapy for Pseudomonas aeruginosa ventilator-associated pneumonia in adults: a randomized, controlled, open-label trial – Intensive Care Medicine (free article here)
Commentary on Twitter
🧫 8 vs 15 days ABT for Pseudomonas aeruginosa VAP in adults, iDIAPASON RCT: no differences in composite or separate outcomes (90-day mortality/VAP recurrence) between short & long duration treatment.
📢 @yourICM ground-breaking release #LIVES40 #FOAMcc
🖇 https://t.co/LfoUWxCkkl pic.twitter.com/XaWkQ5R6wT— Intensive Care Medicine (@yourICM) May 13, 2022
ESC Position Paper: Integrated care for optimizing the management of stroke and associated heart disease.
16 May, 2022 | 02:29h | UTC
Commentary on Twitter
Integrated care for optimizing the management of stroke and associated heart disease: a position paper of the European Society of Cardiology Council on Strokehttps://t.co/L7dPxM6dZx#EHJ #stroke @escardio @ESC_Journals #CardioTwitter pic.twitter.com/MB6mIqzdui
— EHJ Editor-in-Chief (@ehj_ed) May 14, 2022
Under a https://creativecommons.org/licenses/by-nc/4.0/ license