Internal Medicine
Variation in the estimated prevalence of multimorbidity: systematic review and meta-analysis of 193 international studies.
20 May, 2022 | 10:58h | UTC
Commentary on Twitter
Our meta-analysis led by Iris Szu-Szu & Bruce Guthrie
Prevalence of multimorbidity = 42.4%
No difference in prevalence between low-income or middle-income countries
Future studies should use a common core conditions to improve comparabilityhttps://t.co/FdjJ2P4dtN pic.twitter.com/DP3IeWI5sR
— Prof Kamlesh Khunti (@kamleshkhunti) May 19, 2022
M-A: Comparison of Amitriptyline with other FDA–approved treatments for fibromyalgia.
20 May, 2022 | 10:49h | UTC
M-A: Management of asymptomatic severe aortic stenosis.
20 May, 2022 | 10:54h | UTCManagement of asymptomatic severe aortic stenosis: a systematic review and meta-analysis – openheart
Commentaries on Twitter
Management of asymptomatic severe aortic stenosis: a systematic review and meta-analysis @justvick @vass_vassiliou @MarcDweck @jhfrudd https://t.co/eFJbT3AiPn pic.twitter.com/g2GwKvlODW
— Open Heart (@Open_HeartBMJ) May 18, 2022
Our latest work led by #WIC @justvick on earlier surgery in asymptomatic aortic stenosis @Open_HeartBMJ inc all RCT & observational studies – huge suggestion that ‘earlier the better!’ https://t.co/u56LffOjAD great collaboration with @MarcDweck @jhfrudd @HEARTinMagnet #epeeps pic.twitter.com/WlKn1e6c9S
— Vass Vassiliou (@vass_vassiliou) May 18, 2022
Overview of complications in cirrhosis.
20 May, 2022 | 10:37h | UTCOverview of Complications in Cirrhosis – Journal of Clinical and Experimental Hepatology
Systematic Review | Post-stroke dysphagia: prognosis and treatment.
20 May, 2022 | 10:33h | UTC
UK, Spain, Portugal report more monkeypox cases.
19 May, 2022 | 11:15h | UTCUK, Spain, Portugal report more monkeypox cases – CIDRAP
See also:
U.S. monkeypox case reported, as Spain, Portugal report infections in growing outbreak – STAT
Monkeypox – United Kingdom of Great Britain and Northern Ireland – World Health Organization
Monkeypox cases confirmed in England – latest updates – UK Health Security Agency
Seven Confirmed Monkeypox Cases in UK Includes Sexually Transmitted Cluster – Health Policy Watch
European outbreak of monkeypox: what you need to know – The Conversation
Rare monkeypox outbreak in U.K., Europe and U.S.: What is it and should we worry – NPR
Monkeypox cases under investigation in Canada as outbreak spreads in Europe, U.S. – CBC News
Commentary on Twitter
On the rare monkeypox outbreak in Europe!
Health officials have little clue where people caught the virus. And there's concern the virus may be spreading through the community – undetected – and possibly through a new route of transmission #IDTwitter https://t.co/KOQ8rM2nW9— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 18, 2022
The pandemic’s true health cost: how much of our lives has COVID stolen?
19 May, 2022 | 11:09h | UTCThe pandemic’s true health cost: how much of our lives has COVID stolen? – Nature
Commentary on Twitter
What's missed by our fixation on hospitalization and death metrics for the pandemic—the disability toll—the impact by disability-adjusted life years (DALYs) https://t.co/dFWNuVah3z@HollyElse @Nature #LongCovid pic.twitter.com/Fql0a4ObLH
— Eric Topol (@EricTopol) May 18, 2022
Discovery reveals blocking inflammation may lead to chronic pain.
19 May, 2022 | 11:06h | UTCNews Release: Discovery reveals blocking inflammation may lead to chronic pain – McGill University
Original Study: Acute inflammatory response via neutrophil activation protects against the development of chronic pain – Science Translational Medicine
Commentary on Twitter
Challenging medical dogma:
A very important new report suggests that non-steroidal inflammatory medications for acute pain can lead to chronic painhttps://t.co/Z8yjFFBCkK @ScienceTM https://t.co/YGjkXbvNTa pic.twitter.com/f4xVezAhau— Eric Topol (@EricTopol) May 18, 2022
Opinion | Does Paxlovid help people who have been vaccinated against Covid-19? Show us the data!
19 May, 2022 | 11:07h | UTCDoes Paxlovid help people who have been vaccinated against Covid-19? Show us the data! – STAT
Review: Unexplained post-acute infection syndromes.
19 May, 2022 | 10:58h | UTCUnexplained post-acute infection syndromes – Nature Medicine (if the link is paywalled, try this one)
Commentary on Twitter
A @NatureMedicine tour de force review of the unexplained post-acute infectious syndromes, which includes #LongCovid and many others https://t.co/5RnyY9l0eQ
by @jan_choutka @mhornig @VirusesImmunity pic.twitter.com/dhYeZYnM1U— Eric Topol (@EricTopol) May 18, 2022
Integrating palliative care into the ICU: a lasting and developing legacy.
19 May, 2022 | 10:52h | UTCIntegrating palliative care into the ICU: a lasting and developing legacy – Intensive Care Medicine
Commentary on Twitter
Palliative care in #ICU, 3 recommendations
1️⃣ implement consensus & disseminate skills/training
2️⃣ identify & implement strategies to identify pts/families who would benefit most
3️⃣ deliver/integrate primary/specialty palliative care focused on function
🖇 https://t.co/jtnYotNMgJ pic.twitter.com/Ga4J9tpRdx— Intensive Care Medicine (@yourICM) May 17, 2022
RCT: An intervention to promote self-management, independence and self-efficacy in people with early-stage dementia did not improve clinical outcomes.
19 May, 2022 | 10:42h | UTC
Prescribing SGLT2 inhibitors in patients with chronic kidney disease: expanding indications and practical considerations.
19 May, 2022 | 10:43h | UTC
Commentary on Twitter
Prescribing #SGLT2 Inhibitors in Patients with #CKD : Expanding Indications and Practical Considerations
👍🏻 This interesting article discusses about practical considerations of #SGLT2i from #nephrology point of view https://t.co/Wq2plAqbhq @Nephro_Sparks @NephJC @kidney_boy pic.twitter.com/eHmpOHso86
— Henry Han (@HanCardiomd) May 17, 2022
Under a CC BY-NC-ND 4.0 license
Podcast: IBS, functional dyspepsia, and cyclic vomiting: disorders of gut brain interaction.
19 May, 2022 | 10:35h | UTC
Palliative care: An update for internists.
19 May, 2022 | 10:33h | UTCPalliative care: An update for internists – Cleveland Clinical Journal of Medicine
Psychogenic nonepileptic seizure: An empathetic, practical approach.
19 May, 2022 | 10:30h | UTCEditorial: Psychogenic nonepileptic seizure: A neurologist’s perspective
Managing stage 1 hypertension: Consider the risks, stop the progression.
19 May, 2022 | 10:27h | UTC
AHA/ASA Guideline: Management of patients with spontaneous intracerebral hemorrhage.
18 May, 2022 | 12:01h | UTCTop Things to Know: 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage – American Heart Association
News Release: New guideline refines care for brain bleeds: compression socks, some meds not effective – American Heart Association
Commentary on Twitter
Released today: Guidelines for treating spontaneous ICH
Includes:
➡️ Acute reversal of anticoagulation after ICH
➡️Updates to common interventions
➡️Minimally invasive surgical recommendations✍️ @SMGreenbergNeur @WendyZiai
📍 @StrokeAHA_ASA https://t.co/6YQ2TLy3NW pic.twitter.com/y93qQGCmfV
— AHA Science (@AHAScience) May 17, 2022
RCT: Effect of transcatheter aortic valve implantation vs. surgical aortic valve replacement on all-cause mortality in patients with aortic stenosis.
18 May, 2022 | 11:12h | UTCEffect of Transcatheter Aortic Valve Implantation vs Surgical Aortic Valve Replacement on All-Cause Mortality in Patients With Aortic Stenosis: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Treatment of Aortic Stenosis With Transcatheter Aortic Valve Implantation – JAMA (free for a limited period)
Commentary on Twitter
In this study, among patients aged 70 years or older with severe, symptomatic aortic stenosis and moderately increased operative risk, treatment with TAVI was noninferior to surgery with respect to all-cause mortality at 1 year. https://t.co/ORegyw1PKs
— JAMA (@JAMA_current) May 17, 2022
ASCO Guideline: Exercise, diet, and weight management during cancer treatment.
18 May, 2022 | 11:28h | UTC
Commentary on Twitter
🏃🥗🍎🚴♀️ ICYMI: @ASCO issued a new guideline on exercise, diet, and weight management during #CancerTreatment.
Read more ➡️ https://t.co/p5gUEi0ZU0 #pallonc #supponc #exerciseoncology #JCO pic.twitter.com/wGQnAzMBCC
— Journal of Clinical Oncology (@JCO_ASCO) May 17, 2022
RCT: Effect of oral methylprednisolone on decline in kidney function or kidney failure in patients with IgA nephropathy.
18 May, 2022 | 11:20h | UTCEffect of Oral Methylprednisolone on Decline in Kidney Function or Kidney Failure in Patients With IgA Nephropathy: The TESTING Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Oral Glucocorticoids for IgA Nephropathy – JAMA
Commentary: Multi-country study provides a clear treatment option for IgA nephropathy – News Medical
Management of drug interactions with Nirmatrelvir/Ritonavir (Paxlovid).
18 May, 2022 | 11:03h | UTCCommentary: IDSA offers guidance on managing drug interactions with nirmatrelvir/ritonavir – ACP Internist
Related:
Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
Covid-19: What is the evidence for the antiviral Paxlovid? – The BMJ
Yes, Relapses After Paxlovid Happen — Now What? – HIV and ID Observations
A living WHO guideline on drugs for covid-19 – The BMJ
[Preprint] Effectiveness of a second COVID-19 vaccine booster on all-cause mortality in long-term care facility residents and in the oldest old: a nationwide, retrospective cohort study in Sweden.
18 May, 2022 | 11:05h | UTC
Commentary on Twitter
Confirmation of the 2nd booster protection from death in people age 80+ in Sweden, with a relative vaccine effectiveness 42% (compared w/ the 1st booster)https://t.co/Dq1x00J3Tr pic.twitter.com/fyXJPEcQzC
— Eric Topol (@EricTopol) May 17, 2022
Guideline of guidelines: management of recurrent urinary tract infections in women.
18 May, 2022 | 10:59h | UTC
M-A: Comparison of power training vs. traditional strength training on physical function in older adults.
18 May, 2022 | 10:57h | UTCCommentaries:
Review: Power Training, Strength Training Compared for Older Adults- HealthDay
Commentary on Twitter
This systematic review and meta-analysis of RCTs demonstrated that power training was associated with a modest improvement in physical function compared to traditional strength training in healthy, community living older adults. https://t.co/EfA3D2q6DJ
— JAMA Network Open (@JAMANetworkOpen) May 11, 2022


