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Infectious Diseases (all articles)

Perspective | Can ‘zero COVID’ countries continue to keep the virus at bay once they reopen?

16 Sep, 2021 | 10:04h | UTC

Can ‘zero COVID’ countries continue to keep the virus at bay once they reopen? – Science

 

A guide to the treatment of cellulitis and other soft-tissue infections.

16 Sep, 2021 | 09:47h | UTC

A guide to the Tx of cellulitis and other soft-tissue infections – Journal of Family Practice

 

Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

15 Sep, 2021 | 10:01h | UTC

Daily testing for contacts of individuals with SARS-CoV-2 infection and attendance and SARS-CoV-2 transmission in English secondary schools and colleges: an open-label, cluster-randomised trial – The Lancet

Invited commentary: Daily antigen testing to reduce disruption when schools return – The Lancet

 

RCT: Remdesivir does not improve outcomes in patients admitted to hospital with COVID-19.

15 Sep, 2021 | 09:59h | UTC

Remdesivir plus standard of care versus standard of care alone for the treatment of patients admitted to hospital with COVID-19 (DisCoVeRy): a phase 3, randomised, controlled, open-label trial – The Lancet Infectious Diseases

Invited commentary: Remdesivir, on the road to DisCoVeRy – The Lancet Infectious Diseases

Related:

Systematic Review: “Remdesivir probably has little or no effect on all‐cause mortality at up to 28 days in hospitalized adults with SARS‐CoV‐2 infection. We are uncertain about the effects of remdesivir on clinical improvement and worsening”.

WHO Solidarity Trial: Remdesivir, hydroxychloroquine, lopinavir, and interferon regimens had little or no effect on hospitalized patients with Covid-19

 

Review | Prevention of host-to-host transmission by SARS-CoV-2 vaccines.

15 Sep, 2021 | 09:16h | UTC

Prevention of host-to-host transmission by SARS-CoV-2 vaccines – The Lancet Infectious Diseases

Related:

Study ties COVID vaccines to lower transmission rates.

Effect of Vaccination on Household Transmission of SARS-CoV-2 in England – “the likelihood of household transmission was approximately 40 to 50% lower in households of index patients who had been vaccinated 21 days or more before testing positive than in households of unvaccinated index patients”.

Study in England showed one dose of COVID-19 vaccine can cut household transmission by up to half – This protection is on top of the reduced risk of a vaccinated person developing symptomatic infection, which is around 60 to 65% after the first dose

Covid-19 vaccination prevents transmission from vaccinated to unvaccinated household members.

 

Ivermectin: Cochrane’s most talked about review so far, ever. Why?

15 Sep, 2021 | 09:07h | UTC

Ivermectin: Cochrane’s most talked about review so far, ever. Why? – Cochrane Library

Original review: Systematic review: no evidence to support the use of Ivermectin for treating or preventing COVID-19.

 

Commentary on Twitter

 

CDC report finds unvaccinated people are 11 times more likely to die of COVID-19.

15 Sep, 2021 | 09:09h | UTC

Unvaccinated People Are 11 Times More Likely To Die Of COVID-19, New Research Finds – NPR

Original study: Monitoring Incidence of COVID-19 Cases, Hospitalizations, and Deaths, by Vaccination Status — 13 U.S. Jurisdictions, April 4–July 17, 2021 – CDC Morbidity and Mortality Weekly Report

 

Commentary on Twitter

 

The tangled history of mRNA vaccines.

15 Sep, 2021 | 09:06h | UTC

The tangled history of mRNA vaccines – Nature

Related:

mRNA vaccines for infectious diseases: principles, delivery and clinical translation.

After COVID-19 successes, researchers push to develop mRNA vaccines for other infectious diseases and cancer.

 

Commentary on Twitter

 

How COVID is derailing the fight against HIV, TB and malaria.

15 Sep, 2021 | 09:01h | UTC

How COVID is derailing the fight against HIV, TB and malaria – Nature

Related:

How COVID hurt the fight against other dangerous diseases

World TB Day | Report: COVID-19 Eliminates Twelve Years of Progress Against Tuberculosis

WHO: Benefits of continuing to provide life-saving HIV services outweigh the risk of COVID-19 transmission by 100 to 1

 

The USPSTF maintains the recommendation to screen for chlamydia and gonorrhea in all sexually active women 24 years or younger and in women 25 years or older who are at increased risk for infection.

15 Sep, 2021 | 08:57h | UTC

Final Recommendation Statement: Screening for Chlamydia and Gonorrhea – U.S. Preventive Services Task Force

Editorial: Screening for Chlamydia and Gonorrhea – JAMA

Evidence Report : Screening for Chlamydial and Gonococcal Infections: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author Interview: USPSTF Recommendation: Screening for Chlamydia and Gonorrhea

JAMA Patient Page: Screening for Chlamydia and Gonorrhea

 

Systematic Review: Does hair removal before surgery prevent infections after surgery?

15 Sep, 2021 | 08:47h | UTC

Summary: Does hair removal before surgery prevent infections after surgery? – Cochrane Library

Original study: Preoperative hair removal to reduce surgical site infection – Cochrane Library

 

Commentary on Twitter

https://twitter.com/CochraneUK/status/1433731563318042624

 

An update on prevention of malaria in travelers.

15 Sep, 2021 | 08:39h | UTC

An update on prevention of malaria in travelers – Therapeutic Advances in Infectious Disease

Related: CDC Yellow Book

 

Report: Fully vaccinated people account for 1.2% of England’s Covid-19 deaths.

14 Sep, 2021 | 10:07h | UTC

Fully vaccinated people account for 1.2% of England’s Covid-19 deaths – The Guardian

Original Report: Deaths involving COVID-19 by vaccination status, England: deaths occurring between 2 January and 2 July 2021 – Office for National Statistics

 

COVID-19 vaccine efficacy does not support boosters for general population, review concludes.

14 Sep, 2021 | 10:08h | UTC

News release: COVID-19 vaccine efficacy does not support boosters for general population, review concludes – The Lancet

Original article: Considerations in boosting COVID-19 vaccine immune responses – The Lancet

Commentaries:

FDA experts among group opposing US booster shot plan – Associated Press

FDA vaccine regulators argue against Covid-19 vaccine boosters in new international review – STAT

Global experts pan wider use of COVID vaccine booster dose – CIDRAP

Expert reaction to viewpoint article on COVID-19 booster vaccines for general populations – Science Media Centre

Boosters Are ‘Not Appropriate’ – Reach Unvaccinated First – Health Policy Watch

Data Doesn’t Support Need for COVID-19 Vaccine Boosters: Experts – HealthDay

In a new review, some F.D.A. scientists and others say boosters aren’t needed for the general population. – The New York Times

 

Covid: Single jab recommended for 12 to 15-year-olds by UK’s top doctors.

14 Sep, 2021 | 10:05h | UTC

Covid: Single jab recommended for 12 to 15-year-olds by UK’s top doctors – BBC

See also: Covid-19: Children aged 12-15 should be offered vaccine, say UK’s chief medical officers – The BMJ

 

Massive numbers of new COVID–19 infections, not vaccines, are the main driver of new coronavirus variants.

14 Sep, 2021 | 09:56h | UTC

Massive numbers of new COVID–19 infections, not vaccines, are the main driver of new coronavirus variants – The Conversation

 

Review | The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology.

14 Sep, 2021 | 09:58h | UTC

The next phase of SARS-CoV-2 surveillance: real-time molecular epidemiology – Nature Medicine

 

Commentary on Twitter

 

Vaccines Will Not Produce Worse Variants.

14 Sep, 2021 | 09:53h | UTC

Vaccines Will Not Produce Worse Variants – Science

 

Antifungal Susceptibility Testing: A Primer for Clinicians.

14 Sep, 2021 | 08:46h | UTC

Antifungal Susceptibility Testing: A Primer for Clinicians – Open Forum Infectious Diseases

 

Commentary on Twitter

 

Four factors that increase the risk of vaccinated people getting COVID.

12 Sep, 2021 | 22:02h | UTC

Four factors that increase the risk of vaccinated people getting COVID – The Conversation

Original study: Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case-control study – The Lancet Infectious Diseases

 

What’s the evidence for COVID-19 booster shots?

12 Sep, 2021 | 22:05h | UTC

What’s the evidence for COVID-19 booster shots? – Canadian Medical Association Journal

 

Perspective | We’re Asking the Impossible of Vaccines – “Complete protection against infection has long been hailed as the holy grail of vaccination. It might simply be unachievable”.

12 Sep, 2021 | 21:59h | UTC

We’re Asking the Impossible of Vaccines – The Atlantic

 

Commentary on Twitter

 

Risk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions.

12 Sep, 2021 | 22:03h | UTC

Risk of severe breakthrough Covid-19 higher for seniors and people with underlying conditions – CNN

Original study: Hospitalisation among vaccine breakthrough COVID-19 infections – The Lancet Infectious Diseases

News release: Study examines severe breakthrough cases of COVID-19 – YaleNews

 

Commentary on Twitter

 

Perspective | How Endemic COVID Becomes a Manageable Risk – “Businesses and schools must adapt, because the dual threat from the coronavirus and the flu will be too severe”.

12 Sep, 2021 | 21:58h | UTC

How Endemic COVID Becomes a Manageable Risk – The Atlantic

 

Commentary on Twitter

 

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

12 Sep, 2021 | 21:54h | UTC

One-Year Outcomes of Critical Care Patients Post–COVID-19 Multisystem Inflammatory Syndrome in Children – JAMA Pediatrics

Commentary: Outcome Good at One Year for Majority of PIMS-TS Patients – HealthDay

 

Commentary on Twitter

 

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