Infectious Diseases (all articles)
Case series: COVID-19 mRNA vaccination leading to CNS inflammation.
7 Sep, 2021 | 10:49h | UTCCOVID-19 mRNA vaccination leading to CNS inflammation: a case series – Journal of Neurology
Opinion | Video: Immunity is the only way through a pandemic (w/Dr. Monica Gandhi).
7 Sep, 2021 | 10:45h | UTCImmunity Is The Only Way Through A Pandemic (w/Dr. Monica Gandhi) – ZDoggMD
CDC report: Hospitalization rates for Covid-19 were 10 times higher among unvaccinated than among fully vaccinated adolescents.
7 Sep, 2021 | 10:52h | UTCCommentaries:
More kids hospitalized with Covid-19 in states with lower vaccination rates, CDC report finds – CNN
Child COVID hospital cases up in low-vaccination states – CIDRAP
Commentary on Twitter
From late June to mid-August, there was a 10x increase in the rate of hospitalizations among children ages 0-4 with #COVID19 while the #DeltaVariant was widely circulating. It is critical for children to #maskup and get vaccinated if eligible. Learn more: https://t.co/aHC1vYdKVG. pic.twitter.com/uUeNPG6d5r
— CDC (@CDCgov) September 3, 2021
[Not published yet] Sinovac booster shot reverses drop in antibody activities against Delta-study.
7 Sep, 2021 | 10:47h | UTCSinovac booster shot reverses drop in antibody activities against Delta-study – Reuters
Commentary on Twitter
A booster dose of Sinovac Biotech's COVID-19 vaccine reversed a decline in antibody activities against the Delta variant, a study showed, easing some concerns about its longer-term immune response to the highly contagious strain of the virus. https://t.co/QdmMYVBrvl
— Reuters Health (@Reuters_Health) September 6, 2021
More data showing increased risk of hospitalization with SARS-CoV-2 delta variant.
6 Sep, 2021 | 11:12h | UTCHospitalisation associated with SARS-CoV-2 delta variant in Denmark – The Lancet Infectious Diseases
The resurgence of SARS-CoV-2 infection in a highly vaccinated health system workforce; vaccine effectiveness against infection was reduced from above 90% from March through June to 65% in July.
6 Sep, 2021 | 11:09h | UTCRelated:
Another study shows Pfizer mRNA vaccine immunity is reduced over time.
Commentary on Twitter (thread – click for more)
? NEW DATA?
1/ "Resurgence of SARS-CoV-2 Infection in a Highly Vaccinated Health System Workforce" published today in @NEJM details ↓ in vaccine effectiveness against INFECTION among @UCSDHealth employees – from 95%+ in the spring to 65% in July
?? https://t.co/wMgjoLgJzS pic.twitter.com/lgOwlEqUQG
— Christopher A. Longhurst (@calonghurst) September 1, 2021
RCT: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels.
6 Sep, 2021 | 11:11h | UTC
Commentary on Twitter
The SAVE-MORE phase 3 study demonstrates the efficacy of anakinra, an IL-1α/β inhibitor, in patients with COVID-19 and high serum levels of soluble plasminogen activator receptor, according to a @NatureMedicine paper. https://t.co/aM5teLMipK pic.twitter.com/bTVNqbBOcv
— Nature Portfolio (@NaturePortfolio) September 3, 2021
Large surveillance study finds severe adverse events after COVID-19 mRNA vaccination are rare.
6 Sep, 2021 | 11:02h | UTCSurveillance for Adverse Events After COVID-19 mRNA Vaccination – JAMA
Editorial: Safety Surveillance of COVID-19 mRNA Vaccines Through the Vaccine Safety Datalink – JAMA
Commentaries:
mRNA COVID vaccines not tied to serious side effects – CIDRAP
Researchers find no serious health effects linked to mRNA COVID-19 vaccines – News Medical
Commentary on Twitter
Concerned about the safety of mRNA vaccines? This study of 6.2 million people who got 11.8 million doses is immensely reassuring. https://t.co/nUIqTacl0g pic.twitter.com/JBvenRVrRc
— David Juurlink (@DavidJuurlink) September 4, 2021
Viewpoint | Strengthening global health security and reforming the international health regulations: making the world safer from future pandemics.
6 Sep, 2021 | 11:00h | UTC
Interactive infographic showing the effects of Delta: How coronavirus spreads through a population and how we can beat it.
6 Sep, 2021 | 10:59h | UTCHow coronavirus spreads through a population and how we can beat it – The Guardian
Infographic: Vaccine passports around the world.
3 Sep, 2021 | 10:27h | UTCVaccine passports around the world – The BMJ
Double vaccination halves risk of Long COVID.
3 Sep, 2021 | 10:29h | UTCNews release: Double vaccination halves risk of Long COVID – King’s College London
Commentaries:
Largest study of its kind finds face masks reduce COVID-19 – University of California – Berkeley
Study: Vaccines slash long-haul COVID, hospital rates – CIDRAP
Vaccination reduces risk of long Covid, even when people are infected, U.K. study indicates – STAT
Being fully vaccinated reduces odds of long-term Covid-19 symptoms by half, UK study suggests – CNN
Coronavirus vaccines cut risk of long Covid, study finds – BBC
Related: M-A: More than 50 long-term effects of COVID-19.
Commentary on Twitter
NEW evidence on breakthrough infections indicates people who tested positive for #SARS-CoV-2 after 1 or 2 vaccine doses had significantly lower odds of severe disease, hospitalisation, or #LongCOVID than unvaccinated. https://t.co/MgHt7Ztqa0 @TheLancetInfDis pic.twitter.com/nt2b7jVrH9
— The Lancet (@TheLancet) September 1, 2021
WHO says it is monitoring a new Covid variant called ‘mu’.
3 Sep, 2021 | 10:21h | UTCWHO says it is monitoring a new Covid variant called ‘mu’ – CNBC
See also:
What’s the Mu variant? And will we keep seeing more concerning variants? – The Conversation
WHO monitoring new coronavirus variant named ‘Mu’ – France 24
New ‘mu’ coronavirus variant could escape vaccine-induced immunity, WHO says – LiveScience
WHO monitoring new coronavirus variant named Mu – The Guardian
[Preprint] Largest study of masks yet details their importance in fighting Covid-19.
3 Sep, 2021 | 10:30h | UTCLargest study of masks yet details their importance in fighting Covid-19 – NBC News
Original study: The Impact of Community Masking on COVID-19: A Cluster-Randomized Trial in Bangladesh – Innovations for Poverty Action
See also: A Study In Bangladesh Tripled The Rate Of Mask-Wearing. Can It Help In The U.S.? – NPR
Commentaries on Twitter (thread – click for more)
This is arguably the most important single piece of epidemiological research of the entire pandemic.
A MASSIVE randomized trial launched a pro-mask campaign in some Bangladeshi villages, but not others.
The result: masking villages got less COVID. https://t.co/8uKPXAvvnU
— Lyman Stone 石來民 ??? (@lymanstoneky) September 1, 2021
(thread from the author – click for more)
Some misinterpretation of our #Bangladesh Mask RCT by those who don’t read research, which I’ll ignore, but also some parochial/racist reactions, which I must respond to https://t.co/FFeqz1zox5
— Ahmed Mushfiq Mobarak (@mushfiq_econ) September 2, 2021
EU agency says to focus on vaccines first not booster shots.
3 Sep, 2021 | 10:34h | UTCEU agency says to focus on vaccines first not booster shots – Associated Press
See also: European officials say COVID-19 booster isn’t urgent – CIDRAP
Opinion | “The downsides of masking young students are real”.
3 Sep, 2021 | 10:24h | UTCThe Downsides of Masking Young Students Are Real – The Atlantic
Commentary with a rebuttal on Twitter (thread – click for more)
I'm not greatly interested in the school/mask debate, but I must say this is pretty wild – the article leads with this statement and then proceeds to offer no evidence whatsoever of any harms except "subjective [sic] shortness of breath" https://t.co/JL1Iadt8fy pic.twitter.com/5bZmvOhWo7
— Health Nerd (@GidMK) September 2, 2021
Reimagining construction and renovation of health care facilities during emergence from a pandemic.
3 Sep, 2021 | 10:19h | UTC
RCT: Baricitinib reduced mortality in hospitalized adults with COVID-19.
2 Sep, 2021 | 10:17h | UTCCommentaries:
Commentaries on Twitter
NEW—Baricitinib did not improve the composite primary endpoint of progression to NIV,
high-flow O2, IMV, or death; however, it did reduce 28-day all-cause mortality by 38·2% vs placebo (HR 0·57 [95% CI 0·41–0·78])Read the COV-BARRIER study: https://t.co/QrU6GW0XcQ#ISICEM2021
— The Lancet Respiratory Medicine (@LancetRespirMed) September 1, 2021
(thread – click for more)
1/?? NEW COVID THERAPY SAVES LIVES
Adding baricitinib to steroids will save 1,000s of hospitalized #COVID pts. Our @LancetRespirMed COV-Barrier study is FREE.
I explain?why it’s such a great #Pandemic discovery story: a new way to ⬇️ COVID19 deaths.https://t.co/8I5BlwyT2R pic.twitter.com/6KcfQrljqC
— WesElyMD (@WesElyMD) September 1, 2021
Review | COVID-19 and immune-mediated inflammatory diseases: effect of disease and treatment on COVID-19 outcomes and vaccine responses.
2 Sep, 2021 | 10:06h | UTC
Commentary on Twitter
NEW REVIEW—COVID-19 and immune-mediated inflammatory diseases
Filippo Fagni and colleagues @UniFAU review the effect of disease and treatment on #COVID19 outcomes and #vaccine responseshttps://t.co/ue8XnDF1sM #LancetRheumatology @KorayTascilar pic.twitter.com/Yrk4SmeSbE
— The Lancet Rheumatology (@TheLancetRheum) August 27, 2021
Long COVID: the physical and mental health of children and non-hospitalized young people after SARS-CoV-2 infection – one in seven children may still have symptoms 15 weeks after infection.
2 Sep, 2021 | 10:10h | UTCCommentaries:
Long Covid in children ‘nowhere near scale feared’ – BBC
Related:
Cohort study: Risk factors for long covid in previously hospitalized children.
M-A: More than 50 long-term effects of COVID-19.
Commentary on Twitter (thread – click for more)
The worlds biggest study of post acute #COVID19 symptoms in children is out as a pre-print – the CLoCK study!
Fortunately results are very reassuring regarding symptom frequency and impact
Some important lessons, let's take a look ?
— Alasdair Munro (@apsmunro) September 1, 2021
Another study shows Pfizer mRNA vaccine immunity is reduced over time.
2 Sep, 2021 | 10:05h | UTCWaning of BNT162b2 vaccine protection against SARS-CoV-2 infection in Qatar – medRxiv
Related:
Studies: COVID vaccine protection waning against infection but not hospitalization.
Pfizer says it’s time for a Covid booster; FDA and CDC say not so fast.
Commentary on Twitter (thread – click for more)
The evidence of mRNA vaccine effectiveness (VE) waning grows: large Qatar experience shows substantial 5 month attrition for symptomatic infection VE below 50% and, to a lesser extent, vs hospitalization and deathhttps://t.co/4lIG68Bxm0 pic.twitter.com/rnyo0Si3RP
— Eric Topol (@EricTopol) August 27, 2021
Scientific Statement: Coronavirus Disease-2019 and Heart Failure.
2 Sep, 2021 | 10:08h | UTC
Commentary on Twitter
Released today: Coronavirus Disease-2019 and Heart Failure: A Scientific Statement from @HFSA, published in @JCardFail. @dranulala @ankeetbhatt @EricAdler17 @BhadeliaMD @AshishCorrea @ersied727 @heartofthemater @AndrewJSauer @NMHheartdoc @scottdsolomon https://t.co/fyWab32ruU pic.twitter.com/8pNY60I6gD
— HFSA (@HFSA) September 1, 2021
Recommendations for ventilation of indoor spaces to reduce COVID-19 transmission.
2 Sep, 2021 | 10:02h | UTCRelated:
We studied how to reduce airborne COVID spread in hospitals. Here’s what we learnt.
WHO: Roadmap to improve and ensure good indoor ventilation in the context of COVID-19
CDC releases new ventilation guidelines for indoor environments to reduce Covid-19 risk
Treatment of urinary tract infections in infants <2 Months: A Living Systematic Review - short and long duration of parenteral antibiotics were associated with a similar risk of UTI recurrence.
2 Sep, 2021 | 08:19h | UTCTreatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics
World leaders and experts call for significant reduction in the use of antimicrobial drugs in global food systems.
2 Sep, 2021 | 08:13h | UTCCommentary: Global group urges limits on antimicrobials in food production – CIDRAP