Infectious Diseases (all articles) | Page 53 of 298 | Links Medicus Content Curation & Alerts in Medicine

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies.

14 Mar, 2022 | 01:04h | UTC

Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies – Intensive and Critical Care Nursing

Review: Mycobacterial skin infection.

14 Mar, 2022 | 00:59h | UTC

Mycobacterial skin infection – Current Opinion in Infectious Diseases

RCT: Effectiveness of Fosfomycin for treating multidrug-resistant Escherichia coli bacteremic urinary tract infections.

14 Mar, 2022 | 00:53h | UTC

Effectiveness of Fosfomycin for the Treatment of Multidrug-Resistant Escherichia coli Bacteremic Urinary Tract Infections: A Randomized Clinical Trial – JAMA Network Open

Commentaries:

The Role of Intravenous Fosfomycin: Finding Our Way Out of Dante’s Forest Dark – JAMA Network Open

Fosfomycin Not Noninferior to Comparators for Bacteremic UTI – HealthDay

‘Forgotten’ antibiotic recovered for resistant bacterial infections – University of Seville

Commentary on Twitter

In this RCT, fosfomycin did not demonstrate noninferiority in MDR-E coli bacteremic UTI, mostly due to adverse event-related withdrawals in mITT, but showed efficacy in per protocol analysis. #FORESTtrial @jesusrbano https://t.co/oiPtiQo2XA pic.twitter.com/Q44QQb18cN

— JAMA Network Open (@JAMANetworkOpen) January 13, 2022

RCT: Methenamine Hippurate (a non-antibiotic preventive treatment) is noninferior to prophylactic antibiotics for treating recurrent urinary tract infections in women.

11 Mar, 2022 | 10:21h | UTC

Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inferiority trial – The BMJ

News Release: Antiseptic drug as good as antibiotics for preventing recurrent urinary tract infections – BMJ Newsroom

Editorial: Methenamine hippurate for recurrent urinary tract infections – The BMJ

Commentaries:

Trial supports antibiotic alternative for recurrent urinary infections – CIDRAP

Nonantibiotic Prophylaxis Noninferior for Recurrent UTI – HealthDay

Commentary on Twitter

https://twitter.com/bmj_latest/status/1501800030608494596

Systematic Review: Inhaled corticosteroids for the treatment of COVID‐19.

11 Mar, 2022 | 10:18h | UTC

Inhaled corticosteroids for the treatment of COVID‐19 – Cochrane Library

[Preprint] M-A: Inhaled corticosteroids in COVID-19 outpatients.

PRINCIPLE RCT: Inhaled budesonide improves time to recovery from COVID-19 in people at high risk of complications in the community.

Position Paper: Recommendations for the use of topical inhalant budesonide in COVID-19.

RCT: Inhaled budesonide shortens recovery time in non-hospitalized patients with COVID-19

Phase 2 RCT: Inhaled budesonide shows promise for the treatment of early COVID-19

Commentary on Twitter (thread – click for more)

https://twitter.com/CochraneLibrary/status/1501615982208507912

WHO Guidance: Use of SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing.

11 Mar, 2022 | 10:20h | UTC

Use of SARS-CoV-2 antigen-detection rapid diagnostic tests for COVID-19 self-testing – World Health Organization

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21.

11 Mar, 2022 | 10:16h | UTC

Estimating excess mortality due to the COVID-19 pandemic: a systematic analysis of COVID-19-related mortality, 2020–21 – The Lancet

News Release: Global death toll of COVID-19 pandemic may be more than three times higher than official records, estimates of excess deaths indicate – The Lancet

Commentaries:

COVID’s true death toll: far higher than official records – Nature

Covid deaths probably three times higher than records say – BBC

Editorial: “Excess deaths” is the best metric for tracking the pandemic.

The pandemic’s true death toll: millions more than official counts.

We can be confident there have been far more than 5 million global Covid deaths – “Estimating ‘excess’ fatalities, a more robust analysis method, puts the pandemic’s grim toll between 10m and 19m people”.

Global Covid-19 deaths surpass five million.

Effects of the Covid-19 pandemic on life expectancy and premature mortality in 2020 – this time series analysis showed there were more than 28 million excess years of life lost in 2020 in 31 countries.

Under-reporting of deaths limits our understanding of true burden of covid-19.

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

Commentary on Twitter

https://twitter.com/EricTopol/status/1502064507597860872

COVID pandemic 2nd anniversary: 3 things we got wrong, and 3 things to watch out for.

11 Mar, 2022 | 10:07h | UTC

COVID pandemic 2nd anniversary: 3 things we got wrong, and 3 things to watch out for – The Conversation

Another study suggests that a third vaccine dose is necessary to protect populations against the omicron variant.

11 Mar, 2022 | 10:14h | UTC

Clinical severity of, and effectiveness of mRNA vaccines against, covid-19 from omicron, delta, and alpha SARS-CoV-2 variants in the United States: prospective observational study – The BMJ

News Release: Third vaccine dose critical for protecting populations against omicron variant – BMJ Newsroom

Commentary on Twitter

mRNA vaccines are highly effective in preventing covid-19 associated hospital admissions related to the alpha, delta, and omicron variants. But three doses are needed to achieve a similar level of protection against omicron, finds a large US study: https://t.co/YMm176gmby

— The BMJ (@bmj_latest) March 10, 2022

Retrospective Cohort Study: Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination.

11 Mar, 2022 | 10:05h | UTC

Frequency and outcomes of MRI-detected axillary adenopathy following COVID-19 vaccination – European Radiology

Regional lymphadenopathy following COVID-19 vaccination: Literature review and considerations for patient management in breast cancer care.

2 Case Series and Guidance | Lymphadenopathy in COVID-19 Vaccine Recipients

Axillary lymphadenopathy at the time of COVID-19 vaccination: ten recommendations from the European Society of Breast Imaging.

Covid-19: Schedule breast screening before vaccine or 4 to 6 weeks after to avoid false positives, says guidance

SHEA neonatal intensive care unit (NICU) white paper series: Practical approaches for preventing central line-associated bloodstream infections.

11 Mar, 2022 | 09:53h | UTC

SHEA neonatal intensive care unit (NICU) white paper series: Practical approaches for the prevention of central line-associated bloodstream infections – Infection Control and Hospital Epidemiology

News Release: Practical approaches for the prevention of central line-associated bloodstream infections in NICU – Society for Healthcare Epidemiology of America

Efficacy and safety of non-operative management of uncomplicated acute appendicitis compared to appendectomy: an umbrella review of systematic reviews and meta-analyses.

11 Mar, 2022 | 09:49h | UTC

Efficacy and Safety of Non-Operative Management of Uncomplicated Acute Appendicitis Compared to Appendectomy: An Umbrella Review of Systematic Reviews and Meta-Analyses – World Journal of Surgery

Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.

Review: Diagnosis of uncomplicated and complicated appendicitis in adults.

Another RCT evaluating the efficacy and quality of life of antibiotic-only treatment of acute uncomplicated appendicitis.

A Randomized trial comparing antibiotics with appendectomy for appendicitis

Antibiotics alone for uncomplicated appendicitis: Oral Moxifloxacin almost as good as intravenous Ertapenem + oral Levofloxacin

Observational study: 67.1% success rate with nonoperative management of children with uncomplicated appendicitis

Randomized Trial: Quality of Life and Patient Satisfaction at 7-Year Follow-up of Antibiotic Therapy vs. Appendectomy for Uncomplicated Acute Appendicitis

Meta-Analysis: Antibiotic Treatment vs. Appendectomy for Uncomplicated Acute Appendicitis in Adults and Children

Nonoperative treatment for nonperforated appendicitis in children: a systematic review and meta-analysis – Pediatric Surgery International

Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis.

11 Mar, 2022 | 09:39h | UTC

Association between statin use and daptomycin-related musculoskeletal adverse events: A mixed approach combining a meta-analysis and a disproportionality analysis – Clinical Infectious Diseases

Review: Acute cholecystitis.

11 Mar, 2022 | 09:40h | UTC

Acute Cholecystitis: A Review – JAMA (free for a limited period)

Author Interview: Acute Cholecystitis

RCT: In children with nonsevere, drug-susceptible tuberculosis, treatment for 4 months is noninferior to treatment for 6 months.

10 Mar, 2022 | 11:03h | UTC

Shorter Treatment for Nonsevere Tuberculosis in African and Indian Children – New England Journal of Medicine

News Release: Treatment length reduced for children with tuberculosis – University College London

Commentary on Twitter

https://twitter.com/NEJM/status/1501686991888392192

Perspective: Once viewed as a promising COVID-19 treatment, convalescent plasma falls out of favor.

10 Mar, 2022 | 10:47h | UTC

Once Viewed as a Promising COVID-19 Treatment, Convalescent Plasma Falls Out of Favor – JAMA

Perspective: What do we know about Covid’s impact on the brain?

10 Mar, 2022 | 10:46h | UTC

What do we know about Covid’s impact on the brain? – The Guardian

M-A: Outcomes of people living with HIV after hospital discharge.

10 Mar, 2022 | 10:26h | UTC

Outcomes of people living with HIV after hospital discharge: a systematic review and meta-analysis – The Lancet HIV

Commentary on Twitter (thread – click for more)

New: Outcomes of people living with HIV after hospital discharge: a systematic review and meta-analysis by Nathan Ford and colleagues https://t.co/5xurY4Sxm0 #openaccess

— The Lancet HIV (@TheLancetHIV) March 3, 2022

Safety and efficacy of antibiotic de-escalation and discontinuation in high-risk hematological patients with febrile neutropenia: a single-center experience.

10 Mar, 2022 | 10:09h | UTC

Safety and Efficacy of Antibiotic De-escalation and Discontinuation in High-Risk Hematological Patients With Febrile Neutropenia: A Single-Center Experience – Open Forum Infectious Diseases

Commentary on Twitter

OFID: In high-risk hematological patients w/ febrile neutropenia, antibiotic de-escalation and discontinuation prior to neutrophil recovery did not lead to an increase in infectious complications. https://t.co/eUer1fmoc6 #IDSAJournals @PaulSaxMD @DrJLi @FungalDoc @jobadd pic.twitter.com/HuGRYA8YW3

— IDSA (@IDSAInfo) January 5, 2022

Extending the reach of antimicrobial stewardship to pediatric patients.

10 Mar, 2022 | 10:12h | UTC

Extending the Reach of Antimicrobial Stewardship to Pediatric Patients – Infectious Diseases and Therapy

Cohort Study: One-year trajectory of cognitive changes in older survivors of COVID-19 in Wuhan, China.

9 Mar, 2022 | 09:51h | UTC

One-Year Trajectory of Cognitive Changes in Older Survivors of COVID-19 in Wuhan, China: A Longitudinal Cohort Study – JAMA Neurology

WHO says COVID boosters needed, reversing previous call.

9 Mar, 2022 | 09:49h | UTC

WHO says COVID boosters needed, reversing previous call – Associated Press

Commentary on Twitter

Who needs a booster? The @WHO reverses its position and supports "urgent and broad" 3-shot vaccination https://t.co/y5pyY9bJr7 @AP The evidence has supported that move for several months.
"Fully vaccinated" = 3-shots
(or confirmed infection-acquired immunity + 1 shot)

— Eric Topol (@EricTopol) March 8, 2022