Infectious Diseases (all articles) | Page 47 of 298 | Links Medicus Content Curation & Alerts in Medicine

Monkeypox remains an under-recognized and underreported emerging disease. Good clinical management can limit disease severity or death.

Learn about prevention and control of #monkeypox in our 🆕 free online course on #OpenWHO:
👉 https://t.co/3MtOCbiVoI pic.twitter.com/o1NabpyEzD

— World Health Organization (WHO) (@WHO) April 10, 2022

Seminar: Cholera.

13 Apr, 2022 | 09:55h | UTC

Cholera – The Lancet (free registration required)

Cohort Study: Risk of adverse events after covid-19 in Danish children and adolescents and effectiveness of the Pfizer vaccine in adolescents.

12 Apr, 2022 | 10:07h | UTC

Risk of adverse events after covid-19 in Danish children and adolescents and effectiveness of BNT162b2 in adolescents: cohort study – The BMJ

RCT: Single-dose HPV vaccination found effective among young African women.

12 Apr, 2022 | 10:08h | UTC

Efficacy of Single-Dose Human Papillomavirus Vaccination among Young African Women – NEJM Evidence

News Releases:

Study boosts support for single-dose HPV vaccine regimen – University of Washington

One-dose Human Papillomavirus (HPV) vaccine offers solid protection against cervical cancer – World Health Organization

Three-year follow-up of 2-dose versus 3-dose HPV vaccine

Commentary on Twitter (thread – click for more)

🚨 GAME CHANGER 🚨
One-dose Human Papillomavirus (#HPV) vaccine offers solid protection against cervical cancer: WHO https://t.co/3uWlZlCCVK pic.twitter.com/ZKDvpf2qog

— World Health Organization (WHO) (@WHO) April 11, 2022

AHA Scientific Statement: SARS-CoV-2 infection and associated cardiovascular manifestations and complications in children and young adults.

12 Apr, 2022 | 09:59h | UTC

SARS-CoV-2 Infection and Associated Cardiovascular Manifestations and Complications in Children and Young Adults: A Scientific Statement From the American Heart Association – Circulation

News Release: Heart issues after COVID-19 uncommon in children and young adults, more research needed – American Heart Association

Commentary: COVID-19 CV Complications in Children Are Rare, Treatable: AHA Statement – TCTMD

Cohort Study: Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection.

12 Apr, 2022 | 09:57h | UTC

Predictors of severe illness in children with multisystem inflammatory syndrome after SARS-CoV-2 infection: a multicentre cohort study – Canadian Medical Association Journal

News Release: Children older than 5 at higher risk of COVID-19-related multisystem inflammatory syndrome – Canadian Medical Association Journal

Commentary: Older Kids More Vulnerable to MIS-C: Study – HealthDay

More data suggests the Omicron variant causes milder disease compared to the Delta variant.

12 Apr, 2022 | 09:49h | UTC

Symptom prevalence, duration, and risk of hospital admission in individuals infected with SARS-CoV-2 during periods of omicron and delta variant dominance: a prospective observational study from the ZOE COVID Study – The Lancet

Commentary: Covid-19: Symptomatic infection with omicron variant is milder and shorter than with delta, study reports – The BMJ

Another study suggests a lower risk of hospitalization and death from infection with SARS-CoV-2 Omicron variant vs. Delta.

Perspective: Challenges in inferring intrinsic severity of the SARS-CoV-2 Omicron variant.

Early assessment of the clinical severity of the SARS-CoV-2 omicron variant in South Africa.

Cohort Study: Incidence rates and clinical outcomes of SARS-CoV-2 infection with the Omicron and Delta variants in children younger than 5 years in the US.

[Preprint] SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters.

[Preprint] Study showed reduced clinical severity of Covid-19 patients admitted to hospitals in Gauteng, South Africa, during the Omicron-dominant fourth wave – “any combination of a less-virulent virus, comorbidities, high immunity from prior infection(s) or vaccination may be important contributors to this clinical presentation”.

Early data from South Africa hints Omicron variant may cause less severe Covid, but more research is needed.

Too early to tell, but preliminary information from doctors in South Africa suggests the new Covid variant Omicron may be associated with less severe disease.

COVID-19 disease severity in children infected with the Omicron variant.

12 Apr, 2022 | 09:47h | UTC

COVID-19 Disease Severity in Children Infected with the Omicron Variant – Clinical Infectious Diseases

Commentary on Twitter

COVID-19 Disease Severity in Children Infected with Omicron
Among Delta infected
84.2% had mild
15.7% had moderate
0.1% had severe/critical disease
Among Omicron infected
97.8% had mild
2.2% had moderate
None had severe/critical disease (P < .001 https://t.co/ZHhVpY8LuG

— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) April 11, 2022

Empyema: ED presentation, evaluation, and management.

12 Apr, 2022 | 08:44h | UTC

Empyema: ED Presentation, Evaluation, and Management – emDocs

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management.

11 Apr, 2022 | 02:00h | UTC

Clinical update on COVID-19 for the emergency and critical care clinician: Medical management – American Journal of Emergency Medicine

RCT: For adults with HIV, a 4-days-on and 3-days-off treatment strategy is noninferior to standard treatment for maintaining viral suppression.

11 Apr, 2022 | 01:56h | UTC

A 4-days-on and 3-days-off maintenance treatment strategy for adults with HIV-1 (ANRS 170 QUATUOR): a randomised, open-label, multicentre, parallel, non-inferiority trial – The Lancet HIV (link to abstract – $ for full-text)

Commentary: Intermittent Treatment Strategy Is Effective for HIV – Consultant360

Commentaries on Twitter

New: A 4-days-on and 3-days-off maintenance treatment strategy for adults with HIV-1 (ANRS 170 QUATUOR): a randomised, open-label, multicentre, parallel, non-inferiority trial by Roland Landman and colleagues https://t.co/Tc2Rbo1ISt pic.twitter.com/YTV3XwfELo

— The Lancet HIV (@TheLancetHIV) February 3, 2022

In virologically suppressed people with HIV, randomization to intermittent ART (4 days on, 3 off) was non-inf. to daily dosing. Challenges what I thought about level of adherence needed. Is good adherence only needed during the viremic phase? https://t.co/lM8QZW0C9h

— David Serota (@serotavirus) March 16, 2022

Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis.

11 Apr, 2022 | 01:58h | UTC

Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis – The Lancet

Invited Commentary: How to interpret the total number of SARS-CoV-2 infections – The Lancet

Commentary on Twitter (thread – click for more)

Estimating #SARSCoV2 infections across the world is fraught with difficulties, hence the novel approach in the above study.@KayokoShioda & @B_Lopman discuss findings, interpretations, & implications. https://t.co/ua9arLXDOq

— The Lancet (@TheLancet) April 10, 2022

Review: Gastrointestinal post-acute COVID-19 syndrome.

11 Apr, 2022 | 01:49h | UTC

Gastrointestinal post-acute COVID-19 syndrome – Nature Reviews Gastroenterology & Hepatology

Commentary on Twitter

NEW! COMMENT

Gastrointestinal post-acute COVID-19 syndromehttps://t.co/SDAOnQSEp4 #COVID19 #LongCovid pic.twitter.com/CUSoUt0azy

— Nature Reviews Gastroenterology & Hepatology (@NatRevGastroHep) April 9, 2022

RCT: Effect of Gram Stain–Guided initial antibiotic therapy on clinical response in patients with ventilator-associated pneumonia.

11 Apr, 2022 | 01:36h | UTC

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Commentary: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (free registration required)

Commentary on Twitter

RCT found gram stain-guided antibiotic therapy for critically ill patients with VAP was noninferior to guideline-based antibiotics, with a reduction in antipseudomonal & antiMRSA use. https://t.co/1yoHO2pnER

— JAMA Network Open (@JAMANetworkOpen) April 8, 2022

CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study.

11 Apr, 2022 | 01:40h | UTC

CoronaVac vaccine is effective in preventing symptomatic and severe COVID-19 in pregnant women in Brazil: a test-negative case-control study – BMC Medicine

Clinical care of severe acute respiratory infections – Tool kit (COVID-19 adaptation, update 2022).

11 Apr, 2022 | 01:45h | UTC

Clinical care of severe acute respiratory infections – Tool kit – World Health Organization

Commentary on Twitter (thread – click for more)

Updated toolkit for the clinical care of severe acute respiratory infections including:
🔸 severe #pneumonia
🔸 acute respiratory distress syndrome
🔸 sepsis & septic shock

👉 https://t.co/ROvKZz12LT pic.twitter.com/LdcNJiJcxA

— World Health Organization (WHO) (@WHO) April 8, 2022