Infectious Diseases (all articles)
Clinical features of, and risk factors for, severe or fatal COVID-19 among people living with HIV admitted to hospital: analysis of data from the WHO Global Clinical Platform of COVID-19.
13 May, 2022 | 11:28h | UTCInvited Commentary: A collision of pandemics: HIV and COVID-19 – The Lancet HIV
Commentaries on Twitter
New: Clinical features of, and risk factors for, severe or fatal COVID-19 among people living with HIV admitted to hospital: analysis of data from the WHO Global Clinical Platform of COVID-19 by Silvia Bertagnolio and colleagues https://t.co/hAyuWi7fMN #openaccess pic.twitter.com/VmjeYMLPHu
— The Lancet HIV (@TheLancetHIV) May 11, 2022
Clinical features of, and risk factors for, severe or fatal COVID-19 among PLWH admitted to hospital…. https://t.co/KKVKwroy4Z Compared with individuals without HIV, PLWH (96% living in Africa) had 15% ⬆️ odds of severe COVID-19 and were 38% more likely to die in hospital.
— Carlos del Rio (@CarlosdelRio7) May 12, 2022
[Preprint] Long Covid: A systematic review and meta-analysis of 120,970 patients.
13 May, 2022 | 11:30h | UTCLong Covid: A Systematic Review and Meta-Analysis of 120,970 Patients – Preprints with The Lancet
Commentary on Twitter
A systematic #LongCovid review of nearly 200 studies and over 120,000 participants, reinforces the high frequency of symptoms > 6 months, not linked to severity of acute illness, and potential for marked disabilityhttps://t.co/9NYQT1P79G pic.twitter.com/WFzBqghbGI
— Eric Topol (@EricTopol) May 6, 2022
Skeletal infections: microbial pathogenesis, immunity, and clinical management.
13 May, 2022 | 11:03h | UTCSkeletal infections: microbial pathogenesis, immunity and clinical management – Nature Reviews Microbiology (if the link is paywalled, try this one)
Racial and ethnic disparities in estimated excess mortality from external causes in the US, March to December 2020.
13 May, 2022 | 10:57h | UTCRacial and Ethnic Disparities in Estimated Excess Mortality From External Causes in the US, March to December 2020 – JAMA Internal Medicine (free for a limited period)
Commentary on Twitter
In this study, American Indian or Alaska Native and Black populations experienced high rates or excess deaths from external causes (transportation fatalities homicide, and drug-related deaths) during the early #COIVD19 pandemic. https://t.co/RaatdoaFzI
— JAMA Internal Medicine (@JAMAInternalMed) May 11, 2022
Pharmacist-led review tied to better antimicrobial prescribing at discharge.
13 May, 2022 | 10:59h | UTCCommentary: Pharmacist-led review tied to better antimicrobial prescribing at discharge – CIDRAP
Original Study: Pharmacist-Driven Transitions of Care Practice Model for Prescribing Oral Antimicrobials at Hospital Discharge – JAMA Network Open
Systematic Review: Antibiotic prophylaxis for preventing bacterial endocarditis following dental procedures.
12 May, 2022 | 10:24h | UTC
Commentary on Twitter
Have a look at the evidence on antibiotics for preventing bacterial endocarditis in people undergoing dental treatment. Summary here: https://t.co/7uxnkbgt8t. Full review here: https://t.co/3Au3EsHZIU pic.twitter.com/RLsF3fHiZa
— Cochrane Oral Health (@CochraneOHG) May 11, 2022
Capsid inhibition with Lenacapavir in multidrug-resistant HIV-1 infection.
12 May, 2022 | 10:20h | UTCCapsid Inhibition with Lenacapavir in Multidrug-Resistant HIV-1 Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Lenacapavir for HIV Infection in a Multidrug-Resistant Study Cohort – ContagionLive
RCT: Evaluation of mRNA-1273 Covid-19 vaccine in children 6 to 11 years of age.
12 May, 2022 | 10:22h | UTC
Commentary on Twitter
Two 50-μg doses of mRNA-1273 vaccine were found to be safe and effective in inducing immune responses and preventing Covid-19 in children 6 to 11 years of age. https://t.co/A5SBK4zK6E pic.twitter.com/7x4JgOwK57
— NEJM (@NEJM) May 11, 2022
Epidemiological update: Hepatitis of unknown etiology in children.
12 May, 2022 | 10:12h | UTCRelated:
Unexplained hepatitis cases in kids rise to 348 in 20 nations – CIDRAP
Multi-Country – Acute, severe hepatitis of unknown origin in children – World Health Organization
WHO says 12 countries have reported unusual cases of hepatitis in kids – STAT
Could Mysterious Hepatitis Cases be Triggered by COVID-19? – Health Policy Watch
U.S., U.K. investigating unusual cases of hepatitis in young children – STAT
Mysterious liver illness seen in kids in US, Europe – Associated Press
Commentary on Twitter (thread – click for more)
Update: #Hepatitis of unknown aetiology in children – 11 May 2022
Approximately 106 cases have been identified in 14 EU/EEA countries and 450 cases are reported worldwide.
The cause of the disease is still under investigation.
Read more: https://t.co/B0lLm7I0dV— ECDC Outbreaks (@ECDC_Outbreaks) May 11, 2022
M-A: Evaluation of HIV treatment outcomes with reduced frequency of clinical encounters and antiretroviral treatment refills.
12 May, 2022 | 08:04h | UTC
Use of novel strategies to develop guidelines for management of pyogenic osteomyelitis in adults: a WikiGuidelines group consensus statement.
11 May, 2022 | 11:23h | UTCCommentary: A new approach to medical guidelines, taking inspiration from Wikipedia – University of Michigan
Commentary on Twitter
This consensus statement & systematic review uses a WikiGuidelines methodology for clinical guideline development (precluding recommendations based on low-quality data/opinion), addressing 7 questions regarding osteomyelitis management. @BradSpellberg https://t.co/MVjkzC5rdf
— JAMA Network Open (@JAMANetworkOpen) May 10, 2022
Phase 2 RCT: A fourth dose of an mRNA Covid-19 vaccine increases cellular and humoral immunity against SARS-CoV-2.
11 May, 2022 | 11:14h | UTCCommentaries:
What a second booster dose of mRNA COVID-19 vaccines tells us – The Lancet Infectious Diseases
Covid: Fourth-dose jab trial shows good boost – BBC
Commentary on Twitter (thread – click for more)
The results of the @CovBoost fourth dose booster substudy are now online in @TheLancetInfDis
We demonstrated fourth doses of covid vaccines were safe and well tolerated and boost antibody levels above their peak following a third dosehttps://t.co/zGi0iNCAcL
— Alasdair Munro (@apsmunro) May 10, 2022
[Preprint] Modeling transmission of SARS-CoV-2 Omicron in China.
11 May, 2022 | 11:16h | UTCModeling transmission of SARS-CoV-2 Omicron in China – Nature Medicine
Commentary on Twitter
https://twitter.com/EricTopol/status/1524050859054616576
RCT: Doxycycline vs. azithromycin for treating anorectal Chlamydia trachomatis infection in women.
11 May, 2022 | 11:15h | UTCDoxycycline versus azithromycin for the treatment of anorectal Chlamydia trachomatis infection in women concurrent with vaginal infection (CHLAZIDOXY study): a multicentre, open-label, randomised, controlled, superiority trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: Doxycycline Bests Azithromycin for Anogenital Chlamydia in Women — Open-label randomized trial set out to duplicate results from prior studies in men – MedPage Today (free registration required)
Related:
Cohort Study: Community-acquired bacterial meningitis in patients of 80 years and older.
11 May, 2022 | 10:51h | UTC
M-A: Associations between ambient temperature and enteric infections by pathogen.
11 May, 2022 | 10:49h | UTC
Review: Hemophagocytic Lymphohistiocytosis in patients with HIV.
11 May, 2022 | 10:47h | UTCA Review of Hemophagocytic Lymphohistiocytosis in Patients With HIV – Open Forum Infectious Diseases
M-A: Interventions to improve immunization coverage among children and adolescents.
11 May, 2022 | 10:45h | UTC
Legionnaires’ Disease: Update on diagnosis and treatment.
10 May, 2022 | 11:06h | UTCLegionnaires’ Disease: Update on Diagnosis and Treatment – Infectious Diseases and Therapy
Commentary on Twitter
Legionellosis is becoming increasingly important as a public health problem throughout the world; although it is an underreported disease!
Fantastic 🆕💥Review Article @InfectDis_Ther
Legionnaires’ Disease: Update on Diagnosis and Treatment #IDTwitter https://t.co/OvmZZZRz6n pic.twitter.com/vCu7MZdnKs— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 7, 2022
Under a http://creativecommons.org/licenses/by-nc/4.0/ license
Review: First-generation oral antivirals against SARS-CoV-2.
10 May, 2022 | 11:08h | UTCFirst-generation Oral Antivirals Against SARS-CoV-2 – Clinical Microbiology and Infection
Podcast: Inpatient Covid Management.
10 May, 2022 | 11:03h | UTC#332 Inpatient Covid Management with Dr. Nathan Erdmann. – The Curbsiders
Kids get limited COVID protection from world’s most popular vaccines – “First analyses of two Chinese-made vaccines in young children show that the shots do provide 60–65% effectiveness against hospitalization”.
10 May, 2022 | 11:04h | UTCKids get limited COVID protection from world’s most popular vaccines – Nature
Recommendations for change in infection prevention programs and practice.
10 May, 2022 | 10:56h | UTC
WHO launches first ever global report on infection prevention and control.
9 May, 2022 | 02:19h | UTCNews Release: WHO launches first ever global report on infection prevention and control – World Health Organization
Executive Summary: Global report on infection prevention and control – World Health Organization
Commentary on Twitter
A new report from the World Health Organization (WHO) shows that good Infection Prevention and Control (IPC) programmes where good hand hygiene and other cost-effective practices are followed, 70% of those infections can be prevented #IDTwitter #MedEd https://t.co/qo954eXMm8
— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) May 6, 2022
Technical briefing 2: Investigation into acute hepatitis of unknown etiology in children in England.
9 May, 2022 | 02:18h | UTCRelated: With usual suspects ruled out, disease detectives try to crack mystery of viral hepatitis cases in kids (several updates on the subject)
Summary on Twitter (thread – click for more)
NEW: @UKHSA Technical Briefing 2 on Paediatric acute hepatitis in England
A 🧵 ⤵️https://t.co/E9MvVTK505 pic.twitter.com/YZCHdCdt4U
— Meaghan Kall has moved to Bluesky (@kallmemeg) May 6, 2022