Infectious Diseases (all articles)
Cohort Study: Proton‐Pump Inhibitors and Risk of Pneumonia in Older Adults
24 Apr, 2018 | 19:29h | UTCCommentary: Commonly prescribed heartburn drug linked to Pneumonia in Older Adults – University of Exeter (free)
Related: Proton Pump Inhibitors: Review of Emerging Concerns – Mayo Clinic Proceedings (free) AND Complications of Proton Pump Inhibitor Therapy – Gastroenterology (free) AND Adverse effects of proton-pump inhibitor use in older adults: a review of the evidence – Therapeutic Advances in Drug Safety (free) AND Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline – Canadian Family Physician (free)
Source: Hospital Medicine Virtual Journal Club
Research: Antibiotic Use After Removal of Penicillin Allergy Label
24 Apr, 2018 | 18:04h | UTCAntibiotic Use After Removal of Penicillin Allergy Label – Pediatrics (link to abstract – $ for full-text)
Commentaries: Penicillin Allergy Testing Could Save Money, Improve Care – American Academy of Pediatrics (free) AND Delabeling for Penicillin Allergy Found Safe in Children – Medscape (free registration required) AND Removing penicillin allergy label from kids saves antibiotics, money – CIDRAP, in Resistance Scan for Apr 20, 2018 (free)
FDA Approves Rapid Diagnostic Test for Candida Auris
24 Apr, 2018 | 17:57h | UTCFDA approves rapid diagnostic test for Candida auris – CIDRAP (free)
FDA News Release: FDA authorizes new use of test, first to identify the emerging pathogen Candida auris (free)
Related: Tracking Candida auris – CDC (free)
Randomized Trial: 5-Day Nitrofurantoin vs Single-Dose Fosfomycin in Uncomplicated Lower UTI
23 Apr, 2018 | 21:13h | UTCEditorial: Nitrofurantoin vs Fosfomycin: Rendering a Verdict in a Trial of Acute Uncomplicated Cystitis – JAMA (free)
Report: WHO Expert Consultation on Rabies
23 Apr, 2018 | 21:10h | UTCWHO Expert Consultation on Rabies – World Health Organization (free)
News release: WHO publishes new rabies guidelines and recommendations on lifesaving immunization (free)
Revised WHO Recommendation on Use of Dengue Vaccine
23 Apr, 2018 | 21:12h | UTCRevised SAGE recommendation on use of dengue vaccine – World Health Organization (free)
Commentaries: A new dengue vaccine should only be used in people who were previously infected, WHO says – Science (free) AND WHO recommends testing before use of Sanofi’s dengue vaccine – Reuters (free)
Infographics: Global Infections by the Numbers
23 Apr, 2018 | 21:02h | UTCGlobal Infections by the Numbers – Scientific American (free)
UK Man with ‘Worst Ever’ Drug-Resistant Gonorrhea Is Now Cured
23 Apr, 2018 | 21:00h | UTCUK Man with ‘Worst Ever’ Drug-Resistant Gonorrhea Is Now Cured – LiveScience (free)
Other commentaries: ‘World’s worst’ super-gonorrhoea man cured – BBC (free) AND Successful Treatment in UK Very Resistant Gonorrhea Case – Medscape (free registration required) AND Highly resistant gonorrhea case treated successfully with ertapenem – Outbreak News Today (free)
See related report: Multi-drug resistant gonorrhoea in England (free PHE report and commentaries)
Perspective: To Defeat Superbugs, Everyone Will Need Access to Clean Water
23 Apr, 2018 | 20:01h | UTCTo defeat superbugs, everyone will need access to clean water – The Conversation (free) (via @Onisillos)
Perspective: Why Do We Need Vaccines?
23 Apr, 2018 | 16:42h | UTCWhy do we need vaccines? – Welcome Trust (free) (via @greg_folkers)
New U.S. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV
23 Apr, 2018 | 16:41h | UTCGuidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV – AIDSInfo (free)
Review: Rotavirus Infection
20 Apr, 2018 | 00:55h | UTCRotavirus infection – Nature Reviews Disease Primers (free)
High Pevalence Rate of Digestive Tract Bacteria in Duodenoscopes: A Nationwide Study
20 Apr, 2018 | 00:48h | UTCHigh prevalence rate of digestive tract bacteria in duodenoscopes: a nationwide study -Endoscopy (free)
Commentary: Cleaned endoscopes often contaminated – Reuters (free)
Related Article: Residual moisture and waterborne pathogens inside flexible endoscopes: Evidence from a multisite study of endoscope drying effectiveness – American Journal of Infection Control (link to abstract – $ for full-text)
Cohort Study: Antibody Responses to Ebola Vaccine are Sustained for at Least 2 Years
17 Apr, 2018 | 20:00h | UTCDeterminants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentary: In encouraging sign, Ebola vaccine appears to provide long-lasting protection – STAT (free)
Research: Hand Hygiene Notification Machine Learning System Improves Adherence to 100%
15 Apr, 2018 | 23:51h | UTCFeasibility Of A Real-Time Hand Hygiene Notification Machine Learning System In Outpatient Clinics – Journal of Hospital Infection (link to abstract – $ for full-text)
Commentary: Machine learning hand hygiene notifications improve adherence to 100% – Clinical Innovation & Technology (free)
ASGE Guideline: Infection Control During GI Endoscopy
15 Apr, 2018 | 23:38h | UTCASGE guideline for infection control during GI endoscopy – Gastrointestinal Endoscopy (free)
Randomized Controlled Trial: Novel Insecticidal Net Nearly Halves Malaria Infection Rate
15 Apr, 2018 | 23:32h | UTCCommentaries: Insecticide-resistant malaria vectors must be tackled – The Lancet (free) AND Advanced insecticidal nets protect against malaria, study shows – CIDRAP News Scan for Apr 12, 2018 (free) AND ‘Resistance breaking’ mosquito net provides children with greater protection against malaria – London School of Hygiene & Tropical Medicine (free)
“The novel net nearly halves malaria infection rate in Tanzanian children compared to standard long-lasting pyrethroid nets” (from London School of Hygiene & Tropical Medicine)
News Release: Affordable Hepatitis C Treatment Shows 97 Percent Cure Rate
14 Apr, 2018 | 20:32h | UTCRelated: Non-profit’s $300 hepatitis C cure as effective as $84,000 alternative – The Guardian (free) AND Hepatitis C: simplified curative treatments can drive global scale-up – World Health Organization (free)
Review: Epidemiological, Behavioural, and Clinical Factors Associated with Antimicrobial-resistant Gonorrhoea
14 Apr, 2018 | 19:33h | UTC
Review: microbiology and antimicrobial therapy for diabetic foot infections
14 Apr, 2018 | 19:28h | UTCMicrobiology and Antimicrobial Therapy for Diabetic Foot Infections – Infection & Chemotherapy (free)
Meta-analysis: antibiotics for the treatment of skin and soft tissue abscesses
13 Apr, 2018 | 01:41h | UTCCommentary: Meta-Analysis Favors Antibiotics After Drainage of Skin Abscesses – NEJM Journal Watch (free)
See related guideline with infographic: Antibiotics after incision and drainage for uncomplicated skin abscesses: a clinical practice guideline – The BMJ (free) AND Meta-Analysis: Antibiotics for uncomplicated skin abscesses: systematic review and network meta-analysis – BMJ Open (free)
Guidelines for the antibiotic treatment of community-acquired urinary tract infections
13 Apr, 2018 | 01:40h | UTC
Research: respiratory infections as triggers for acute myocardial infarction and stroke
13 Apr, 2018 | 01:35h | UTCCommentaries: Flu and pneumonia infections increase risk of having a heart attack and stroke – European Respiratory Foundation, via Eurekalert (free) AND Do Pneumococcal and Respiratory Virus Infections Trigger Cardiovascular Morbidity? – NEJM Journal Watch (free for a limited period)
See also: related study published recently showing a similar six-fold increase in myocardial infarctions in the week following a flu diagnosis (link to abstract and commentaries).
Retrospective cohort: clinical usefulness of imaging and blood cultures in cellulitis evaluation
13 Apr, 2018 | 01:11h | UTCClinical Usefulness of Imaging and Blood Cultures in Cellulitis Evaluation – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentary: Unnecessary blood tests and imaging common in cellulitis hospitalizations, study finds – ACP Hospitalist (free)
Cluster-randomised crossover trial: effects of antibiotic cycling and mixing on antibiotic resistance in the ICU
13 Apr, 2018 | 01:06h | UTCThe effects of antibiotic cycling and mixing on antibiotic resistance in intensive care units: a cluster-randomised crossover trial – The Lancet Infectious Diseases (link to abstract – $ for full-text)
Commentaries: Antibiotic cycling, mixing don’t affect resistance, study says – CIDRAP (free) AND Antibiotic cycling no better than mixing for reducing Gram-negative resistance in the ICU – Univadis (free registration required)


