Infectious Diseases (all articles)
Meta-Analysis: A Comparison of the Quick-SOFA and Systemic Inflammatory Response Syndrome Criteria in Sepsis
30 Mar, 2018 | 04:29h | UTCRelated meta-analysis and commentaries: Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Mortality in Patients With Suspected Infection: A Systematic Review and Meta-analysis – Annals of Internal Medicine (link to abstract – $ for full-text) AND For mortality prediction, qSOFA has poor sensitivity, moderate specificity, review finds – ACP Hospitalist (free) AND Systemic inflammatory response syndrome criteria may be more sensitive than quick sequential organ failure assessment for predicting mortality in patients with suspected infection – 2 Minute Medicine (free)
“The SIRS was significantly superior to the qSOFA for sepsis diagnosis, and the qSOFA was slightly better than the SIRS in predicting hospital mortality. The association of both criteria could provide a better model to initiate or escalate therapy in patients with sepsis”.
Report: Multi-drug resistant gonorrhoea in England
30 Mar, 2018 | 04:15h | UTCReport: Multi-drug resistant gonorrhoea in England: 2018 – Public Health England (free)
Commentaries: In world first, UK reports high-level gonorrhea resistance – CIDRAP (free) AND First case of super-resistant gonorrhea reported – CNN (free)
Related: Scientists warn that antibiotic-resistant gonorrhoea is on the rise – World Health Organization (free) AND Untreatable Gonorrhea Is Rapidly Spreading. Here’s What You Need to Know – TIME Health (free)
Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in adults with uncomplicated malaria
30 Mar, 2018 | 04:16h | UTCSafety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL): a randomised, double-blind, placebo-controlled trial – The Lancet Infectious Diseases (free registration required)
Commentaries: Ivermectin: repurposing an old drug to complement malaria vector control – The Lancet Infectious Diseases (free registration required) AND LSTM study shows drug that kills mosquitoes could be used to fight malaria – London School of Tropical Medicine (free) AND Common anti-parasitic could be new tool for malaria control – OnMedica (free)
Guideline – Otitis media (acute): antimicrobial prescribing
30 Mar, 2018 | 04:10h | UTCGuideline: Otitis media (acute): antimicrobial prescribing – National Institute for Health and Care Excellence (NICE) (free)
Commentaries: Most common ear infections should not be treated with antibiotics, says NICE (free) AND Common ear infections don’t need antibiotics, health watchdog says – The Guardian (free) AND Antibiotics not recommended for acute otitis, says NICE – OnMedica (free)
Related guideline: Clinical Practice Guideline: Otitis Media with Effusion (Update) – Otolaryngol Head Neck Surg (free) AND Executive Summary – Otolaryngol Head Neck Surg (free)
The impact of social protection and poverty elimination on global tuberculosis incidence
30 Mar, 2018 | 03:52h | UTC#WorldTBDay (March 24, 2018) – The impact of social protection and poverty elimination on global tuberculosis incidence: a statistical modelling analysis of Sustainable Development Goal 1 – The Lancet Global Health (free)
Commentaries: Predicting the effect of improved socioeconomic health determinants on the tuberculosis epidemic – The Lancet Global Health (free) AND Eradicating poverty would dramatically reduce TB cases, study finds – The Guardian (free)
Ending extreme poverty and expanding social protection is estimated to reduce the incidence of tuberculosis by 84.3%.
Antibiotic Therapy Duration in US Adults With Sinusitis
30 Mar, 2018 | 03:52h | UTCAntibiotic Therapy Duration in US Adults With Sinusitis – JAMA Internal Medicine (link to abstract – $ for full-text)
Commentaries: Sinus Infections: Majority of Antibiotics Prescriptions Longer Than Recommended – MedicalResearch.com (free) AND CDC Study Says Sinus Infections Are Treated With Antibiotics Longer Than Necessary – AJMC (free) AND Most Courses of Antibiotics for Sinusitis Are Too Long – NEJM Physician’s First Watch (free)
Related Guideline: IDSA Clinical Practice Guideline for Acute Bacterial Rhinosinusitis in Children and Adults – Clinical Infectious Diseases (free)
The World Health Organization standards for tuberculosis care and management
30 Mar, 2018 | 03:51h | UTC#WorldTBDay (March 24, 2018) – The World Health Organization standards for tuberculosis care and management – European Respiratory Journal (free)
Original Guideline: Compendium of WHO guidelines and associated standards: ensuring optimum delivery of the cascade of care for patients with tuberculosis (free PDF)
“My dream of placing all recent and still valid older WHO TB guidelines into a short compendium, to facilitate life of users, is now accomplished. With this booklet, one can access immediately all WHO standards of TB care”. (via @M_Raviglione see Tweet)
World TB Day, 24 March 2018 – World Health Organization
30 Mar, 2018 | 03:50h | UTC#WorldTBDay (March 24, 2018) – World TB Day, 24 March 2018 – World Health Organization (free resources)
See also: WHO key publications on tuberculosis
Vaccine waning and mumps re-emergence
30 Mar, 2018 | 03:44h | UTCVaccine waning and mumps re-emergence in the United States – Science Translational Medicine (link to abstract – $ for full-text)
Commentaries: Mumps resurgence likely due to waning vaccine-derived immunity – Harvard T.H. Chan School of Public Health (free) AND Mumps Vaccine Effectiveness Declines Over Time. But There’s A Solution – Forbes (free) AND Mumps Vaccine Protection Wanes Over Time, Study Finds – CommonHealth (free) AND Mumps Is On the Rise. A Waning Vaccine Response May Be Why – The New York Times (10 articles per month are free)
“a booster dose at age 18 should be a straight-forward solution to the problem based on models of how mumps spreads” (from Forbes)
Systematic Review: Accuracy of different non-invasive methods for identifying Helicobacter pylori
30 Mar, 2018 | 03:31h | UTCAccuracy of different non-invasive methods for identifying Helicobacter pylori – Cochrane Library (free)
The impact of past vaccination coverage and immunity on pertussis resurgence
30 Mar, 2018 | 03:26h | UTCCommentaries: Decades-long trends, not flawed vaccine, explain resurgent whooping cough – University of Michigan, via ScienceDaily (free) AND More Evidence Explains Why Whooping Cough Cases Are Increasing – Forbes (free) AND Waning Vaccine Protection Contributes to Whooping Cough Comeback – AAAS (free)
High Rates of Prescribing Antimicrobials for Prophylaxis in Children and Neonates
30 Mar, 2018 | 03:27h | UTCCommentaries: Antibiotics often inappropriately prescribed for hospitalized kids, global study suggests – Pediatric Infectious Diseases Society, via ScienceDaily (free) AND Too many hospitalized kids get preventive antibiotics – CIDRAP (free)
Guideline: Alternative Mass Drug Administration Regimens to Eliminate Lymphatic Filariasis
30 Mar, 2018 | 03:08h | UTCGuideline: Alternative Mass Drug Administration Regimens to Eliminate Lymphatic Filariasis – World Health Organization (free)
Systematic Review: Mefloquine for preventing malaria in pregnant women
30 Mar, 2018 | 02:46h | UTCMefloquine for preventing malaria in pregnant women – Cochrane Library (free)
Summary: Mefloquine for preventing malaria in pregnant women (free)
When antibiotics turn toxic
23 Mar, 2018 | 02:43h | UTCWhen antibiotics turn toxic – Nature News (free)
“Commonly prescribed drugs called fluoroquinolones cause rare, disabling side effects. Researchers are struggling to work out why”.
Are we prepared for the looming epidemic threat?
23 Mar, 2018 | 02:36h | UTCAre we prepared for the looming epidemic threat? – The Guardian (free) (via @Onisillos)
Related: The World Is Not Ready for the Next Pandemic – TIME cover story AND The World Is Completely Unprepared for a Global Pandemic – Harvard Business Review (free) AND Seven reasons we’re at more risk than ever of a global pandemic – CNN (free) AND Video: Pandemics – a worrying global public health threat (free)
Research: Behaviors, movements, and transmission of droplet-mediated respiratory diseases during transcontinental airline flights
23 Mar, 2018 | 01:59h | UTCCommentaries: Localized Risk for Infection Transmission on Planes, Study Finds – Medscape (free registration required) AND Researchers Determine Routes of Respiratory Infectious Disease Transmission on Aircraft – Georgia Tech News Center (free) AND Why you should choose your plane seat wisely – Medical News Today (free)
“Direct disease transmission outside of the one-meter area of an infected passenger is unlikely” (from Georgia Tech)
Research: Direct-Acting Antiviral Prophylaxis in Kidney Transplantation From Hepatitis C Virus–Infected Donors to Noninfected Recipients
23 Mar, 2018 | 01:52h | UTCCommentaries: HCV Prophylaxis Could Expand Kidney Availability – Renal & Urology News (free) AND HCV-infected kidney donors could save lives – 2 Minute Medicine (free) AND One year posttransplant, recipients of hepatitis C kidneys disease-free – Johns Hopkins Medicine, ScienceDaily (free)
MMWR Report: Fatal Yellow Fever in Travelers to Brazil
23 Mar, 2018 | 01:51h | UTCMMWR Report: Fatal Yellow Fever in Travelers to Brazil, 2018 – Centers for Disease Control and Prevention (CDC) (free)
Commentaries: Thinking of Going to Brazil? You Will Need a Yellow Fever Vaccination – The New York Times (free) AND Brazil’s yellow fever outbreak, explained – VOX (free)
Research: Infectious Diseases Consultation Reduces 30-Day and 1-Year All-Cause Mortality for Multidrug-Resistant Organism Infections
22 Mar, 2018 | 23:44h | UTCCommentary: ID consults tied to lower death rates in MDR infections – CIDRAP (free)
Research: Risk of stroke in patients with dengue fever
16 Mar, 2018 | 03:24h | UTCCommentary: Dengue fever linked to increased risk of stroke – CMAJ, via ScienceDaily (free)
Research: Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa
16 Mar, 2018 | 02:12h | UTCCommentary: Combo Tx Offers New Hope for Cryptococcal Meningitis – MedPage Today (free registration required)
Research: Pregnancy Outcomes after ZIKV Infection
16 Mar, 2018 | 02:11h | UTCEditorial: Recognizing the Global Impact of Zika Virus Infection during Pregnancy (free)
Quick Take Video Summary: Pregnancy Outcomes after Zika (free)
Commentaries: Study: 7% risk of birth defects in Zika pregnancies – CIDRAP (free) AND Birth defect rate pegged at 7 percent for babies born to Zika-infected women – Reuters (free)
Research: Efficacy of a single-dose regimen of inactivated whole-cell oral cholera vaccine
16 Mar, 2018 | 02:01h | UTCInvited commentary: Cholera control: one dose at a time (free)
“Our results indicate that when such emergencies occur in populations with endemic cholera, the challenges of successfully completing a two-dose regimen should not deter deployment of OCV, because older children and adults will be protected for at least 2 years by a single dose”. (via @Onisillos see Tweet)
Review: Advances in the diagnosis and treatment of Clostridium difficile infections
16 Mar, 2018 | 01:42h | UTCAdvances in the diagnosis and treatment of Clostridium difficile infections – Emerging Microbes and Infections (free)