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Infectious Diseases (all articles)

Systematic Review: Plasma from People who Have Recovered from COVID-19 to Treat Individuals with COVID-19

15 May, 2020 | 03:48h | UTC

Convalescent plasma or hyperimmune immunoglobulin for people with COVID‐19: a rapid review – Cochrane Library

Summary: Plasma from people who have recovered from COVID-19 to treat individuals with COVID-19 – Cochrane Library

 


Study: Airborne Lifetime of Small Speech Droplets and their Potential Importance in SARS-CoV-2 Transmission

15 May, 2020 | 03:43h | UTC

The airborne lifetime of small speech droplets and their potential importance in SARS-CoV-2 transmission – Proceedings of the National Academy of Sciences

Commentaries: Expert reaction to study looking at speech-generated droplets and COVID-19 transmission – Science Media Centre AND Loud Talking Can Spread More than 1,000 Coronavirus Particles in the Air for 14 Minutes: Study – The Science Times AND Simply talking in confined spaces may be enough to spread the coronavirus, researchers say – USA Today AND Loud talking could leave coronavirus in the air for up to 14 minutes – MIT Technology Review

 


Opinion: Masks Help Stop the Spread of Coronavirus

15 May, 2020 | 03:44h | UTC

Masks help stop the spread of coronavirus – the science is simple and I’m one of 100 experts urging governors to require public mask-wearing – The Conversation

Related: Face Masks Against COVID-19: An Evidence Review – Preprints AND Face Masks for the Public During the Covid-19 Crisis

 


ACP Systematic Review: Chloroquine or Hydroxychloroquine Alone or in Combination with Azithromycin for the Prophylaxis or Treatment of COVID-19

15 May, 2020 | 03:32h | UTC

Should Clinicians Use Chloroquine or Hydroxychloroquine Alone or in Combination With Azithromycin for the Prophylaxis or Treatment of COVID-19? – Annals of Internal Medicine

 


Study Commentary: Before/after Study of Short-Course Steroid in COVID-19

14 May, 2020 | 10:09h | UTC

Before/after study of short-course steroid in COVID-19 – PulmCrit

Original Study (Preprint): Early Short Course Corticosteroids in Hospitalized Patients with COVID-19 – medRxiv

 


Meta-Analysis: Manifestations and Prognosis of Gastrointestinal and Liver Involvement in COVID-19

14 May, 2020 | 10:16h | UTC

Manifestations and prognosis of gastrointestinal and liver involvement in patients with COVID-19: a systematic review and meta-analysis – The Lancet Gastroenterology & Hepatology

Related: Gastrointestinal, Hepatobiliary, and Pancreatic Manifestations of COVID-19 (review and guideline) AND Abdominal Imaging Findings in COVID-19: Preliminary Observations – Radiology

 


New Study Does Not Support the Idea that BCG Vaccination Protects Against COVID-19

14 May, 2020 | 10:12h | UTC

SARS-CoV-2 Rates in BCG-Vaccinated and Unvaccinated Young Adults – JAMA

Related: BCG Against Coronavirus: Less Hype And More Evidence, Please – Forbes AND Does BCG vaccination protect against acute respiratory infections and COVID-19? A rapid review of current evidence – CEBM University of Oxford AND Bacille Calmette-Guérin (BCG) vaccination and COVID-19 – World Health Organization

 


Estimating Excess Deaths Associated with the COVID-19 According to Underlying Conditions and Age

14 May, 2020 | 10:05h | UTC

Estimating excess 1-year mortality associated with the COVID-19 pandemic according to underlying conditions and age: a population-based cohort study – The Lancet

Commentaries: Scientists develop online calculator to predict individual’s risk of dying from Covid-19 – The Independent AND Expert reaction to study estimating excess deaths over one year directly or indirectly related to COVID-19 based on underlying health conditions and age of UK population, and making comments on the effect of easing the lockdown – Science Media Centre

See calculator: OurRisk.CoV

 

Related Commentary on Twitter

 


Coronavirus Test Shortages Trigger a New Strategy: Group Screening

14 May, 2020 | 09:53h | UTC

Coronavirus Test Shortages Trigger a New Strategy: Group Screening – Scientific American

Related: Pooling of Samples for Testing for SARS-CoV-2 in Asymptomatic People (studies and commentaries) AND Sample Pooling as a Strategy to Detect Community Transmission of SARS-CoV-2 – JAMA Network

 


Systematic Review: SARS-CoV-2 (COVID-19) and Children

14 May, 2020 | 02:33h | UTC

SARS-CoV-2 (COVID-19): What do we know about children? A systematic review – Clinical Infectious Diseases

Related Systematic Review: SARS-CoV-2 Infection in Children and Adolescents (study and commentaries)

 


Interpreting a Covid-19 Test Result

13 May, 2020 | 02:18h | UTC

Practice Pointer: Interpreting a covid-19 test result – The BMJ

Related: Interpreting Diagnostic Tests for SARS-CoV-2 – JAMA

 


Editorial: Waste in Covid-19 Research

13 May, 2020 | 02:17h | UTC

Waste in covid-19 research – The BMJ

Related Landmark Paper from the Author: Avoidable waste in the production and reporting of research evidence – The Lancet (free registration required)

 

Related Commentary on Twitter

 


New Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19

13 May, 2020 | 02:14h | UTC

Development and Validation of a Clinical Risk Score to Predict the Occurrence of Critical Illness in Hospitalized Patients With COVID-19 – JAMA Internal Medicine

See also: Calculation Tool For Predicting Critical-ill COVID-19 At Admission

Related Preprint Study (just published): Development and validation of the COVID-19 severity index (CSI): a prognostic tool for early respiratory decompensation – medRxiv AND Calculation Tool: https://covidseverityindex.org/

 


Study: A Close Relative of SARS-CoV-2 Found in Bats Offers More Evidence It Evolved Naturally

13 May, 2020 | 02:08h | UTC

A close relative of SARS-CoV-2 found in bats offers more evidence it evolved naturally – Cell Press

Original Article: A novel bat coronavirus closely related to SARS-CoV-2 contains natural insertions at the S1/S2 cleavage site of the spike protein – Current Biology

 


World Report: New Zealand Eliminates COVID-19

13 May, 2020 | 02:10h | UTC

New Zealand eliminates COVID-19 – The Lancet

See also:  How New Zealand ‘eliminated’ Covid-19 after weeks of lockdown – CNN AND New Zealand has ‘effectively eliminated’ coronavirus. Here’s what they did right. – National Geographic AND Why New Zealand’s Coronavirus Elimination Strategy Is Unlikely to Work in Most Other Places – TIME

 


Study Commentary – Virus Wars: Return of Lopinavir/Ritonavir (Along with Ribavirin and Interferon)

13 May, 2020 | 02:12h | UTC

Virus Wars: Return of Lopinavir/Ritonavir (along with ribavirin and interferon) – PulmCrit

Original Article: Triple Therapy Antiviral Combination Seems Promising for COVID-19 in Open-label, Randomized, Phase 2 Trial (study and commentaries)

 


Hydroxychloroquine in Patients with COVID-19: A Systematic Review and Meta-analysis

13 May, 2020 | 01:53h | UTC

“Hydroxychloroquine in patients with COVID-19: A Systematic Review and meta-analysis.” – Diabetes & Metabolic Syndrome: Clinical Research & Reviews

“While initial studies with hydroxychloroquine showed some ray of hope, recent studies that have emerged found either no benefit or a possible harm in COVID-19.”

 


Remdesivir in COVID-19: A Critical Review of Pharmacology, Pre-clinical and Clinical Studies

13 May, 2020 | 01:50h | UTC

Remdesivir in COVID-19: A critical review of pharmacology, pre-clinical and clinical studies – Diabetes & Metabolic Syndrome: Clinical Research & Reviews

“While the first double-blind, randomized-controlled trial (DBRCT) found no significant benefit with remdesivir compared to placebo, preliminary reports from another DBRCT showed a significant faster recovery, without any difference in mortality.”

 


The FDA has Authorized the use of Remdesivir: But There’s no Good Evidence it Reduces Mortality in Covid-19

13 May, 2020 | 01:49h | UTC

The FDA has authorised remdesivir for use in COVID-19 patients: but there’s no good evidence it reduces mortality – CEBM Oxford

 


Observational Study: Hydroxychloroquine, Azithromycin, or Both Not Associated with Lower In-hospital Mortality

12 May, 2020 | 03:39h | UTC

Association of Treatment with Hydroxychloroquine or Azithromycin With In-Hospital Mortality in Patients With COVID-19 in New York State – JAMA

Related: Large Observational Study Finds Hydroxychloroquine Provides no Benefit in Hospitalized Patients with Covid-19

 


AIDS, TB and Malaria Set to Get Deadlier Due To Coronavirus

12 May, 2020 | 03:30h | UTC

AIDS, TB And Malaria Set To Get Deadlier Due To Coronavirus – Forbes

Related: AIDS, TB And Malaria: Coronavirus Threatens The Endgame – Forbes AND The Potential Impact of the COVID-19 Epidemic on HIV, TB and Malaria in Low- and Middle-Income Countries – Imperial College London AND The potential impact of health service disruptions on the burden of malaria: a modelling analysis for countries in sub-Saharan Africa – World Health Organization AND The Potential Impact Of The Covid-19 Response On Tuberculosis In High-Burden Countries: A Modelling Analysis

 


WHO: COVID-19-Related Service Disruptions Could Cause Hundreds of Thousands of Extra Deaths from HIV

12 May, 2020 | 03:31h | UTC

The cost of inaction: COVID-19-related service disruptions could cause hundreds of thousands of extra deaths from HIV – World Health Organization

Original Preprints: Potential effects of disruption to HIV programmes in sub-Saharan Africa caused by COVID-19: results from multiple mathematical models AND Estimation of the potential effects of disruption to HIV programs in sub-Saharan Africa caused by COVID-19: results from multiple models APPENDIX

 

Related Commentary on Twitter

 


Updated WHO Guidance: Considerations for Public Health and Social Measures in the Workplace in the Context of COVID-19

12 May, 2020 | 03:34h | UTC

Considerations for public health and social measures in the workplace in the context of COVID-19 – World Health Organization

 

Related Commentary on Twitter

https://twitter.com/WHO/status/1259874331523518464

 


Study: Smartphone-based App for Tracking Self-reported Symptoms to Predict Potential COVID-19

12 May, 2020 | 03:25h | UTC

Real-time tracking of self-reported symptoms to predict potential COVID-19 – Nature Medicine

Commentaries: New AI diagnostic can predict COVID-19 without testing – King’s College London AND Expert reaction to study looking at possibility of using real-time tracking of self-reported symptoms to predict potential COVID-19 without testing – Science Media Centre AND Coronavirus: research reveals way to predict infection – without a test – The Conversation AND Loss of smell and taste may actually be one of the clearest signs of COVID-19 – Science News

 


Richard Lehman’s Covid-19 Reviews—11 May 2020

12 May, 2020 | 03:22h | UTC

Richard Lehman’s Covid-19 Reviews, 11 May 2020 – The BMJ Opinion

In this weekly round-up, Richard Lehman looks at a personal selection of articles of relevance to clinicians dealing with covid-19

 


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