Infectious Diseases (all articles)
CDC Report: Reduction in severe COVID-19 following the implementation of a national vaccination program in Israel
28 Feb, 2021 | 21:54h | UTCCommentary: Israeli data suggest mass vaccinations led to drop in severe Covid cases, CDC study finds – CNBC
Commentary on Twitter
A new @CDCMMWR from Israel shows preliminary evidence of the effectiveness of vaccination in preventing severe cases of #COVID19. Vaccination among people who are eligible to receive a COVID-19 vaccine can potentially reduce severe disease from COVID-19. https://t.co/CaUAXRVaS4 pic.twitter.com/GyaulMONpZ
— CDC (@CDCgov) February 26, 2021
M-A: Treatment with convalescent plasma is not associated with better outcomes in patients with Covid-19
28 Feb, 2021 | 21:51h | UTCEditorial: Emerging Lessons From COVID-19 for the US Clinical Research Enterprise
Commentary on Twitter
Just out: Our meta-analysis in @JAMA_current
"Among patients with COVID-19, treatment with convalescent plasma compared with control was not associated with improved survival or other positive clinical outcomes"https://t.co/tRqpd9v67m
— Lars G. Hemkens (@LGHemkens) February 26, 2021
CDC Study: Suspected SARS-CoV-2 reinfections in a skilled nursing facility
28 Feb, 2021 | 21:55h | UTCCommentaries: Possible SARS-CoV-2 Reinfection Described at Skilled Nursing Facility – HealthDay AND Reinfections could be more likely among those with a mild first case of COVID-19: case study – CTV News
Commentary on Twitter (thread – Click for more)
📌CDC report: Asymptomatic or mildly symptomatic infections don't always produce sufficient immune response to prevent reinfection. Report of nursing facility found 5 people reinfected ~3 months after initial infection. All 5 had more severe symptoms 2nd time around, one death🧵 pic.twitter.com/m9ix9XJolA
— Dr. Ali Nouri (@AliNouriPhD) February 28, 2021
Short Review: SARS-CoV-2 Vaccines
28 Feb, 2021 | 21:52h | UTCAuthor interview: Coronavirus Vaccines—An Overview
Check out the Table ins this #SARSCoV2 Vaccine Overview – everything you wanted to know about upcoming vaccines – Oxford/AZ, Sputnik, Sinovac, more! https://t.co/TWbgfSKBIP
— JAMA (@JAMA_current) February 26, 2021
Studies: Single dose of vaccine acts as ‘booster’ in those with prior COVID-19 infection
28 Feb, 2021 | 21:49h | UTCStudy 1: Antibody response to first BNT162b2 dose in previously SARS-CoV-2-infected individuals – The Lancet
Commentary on Twitter (thread – click for more)
New on 1-dose @Pfizer vaccine after prior covid
"We show that individuals with previous #SARSCoV2 infection generate strong humoral and cellular responses to one dose of BNT162b2 vaccine, with evidence of high titres of in-vitro live virus neutralisation"https://t.co/2G7TRu57OI pic.twitter.com/sIdB0VarqB— Eric Topol (@EricTopol) February 25, 2021
Identification of 3 clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19
28 Feb, 2021 | 21:45h | UTCInvited Commentary: Anticipating outcomes for patients with COVID-19 and identifying prognosis patterns
Commentary on Twitter
Identification and validation of clinical phenotypes with prognostic implications in patients admitted to hospital with COVID-19 https://t.co/kLtzmF5ZWI 📣 These results might help to better classify patients for clinical management #COVID@SPAIN #COVID@HULP pic.twitter.com/ZVaMuUDfnL
— Alberto M. Borobia (@borobia_am) February 24, 2021
Spain to give just one vaccine dose to under 55-year olds who had COVID-19
28 Feb, 2021 | 21:47h | UTCSpain to give just one vaccine dose to under 55-year olds who had COVID-19 – Reuters
Related: Is One Vaccine Dose Enough After COVID-19 Infection? – NIH Director’s Blog AND France’s health authority recommends single vaccine shot for people who have had COVID-19
Long Read | 5 Pandemic Mistakes We Keep Repeating
28 Feb, 2021 | 21:43h | UTC5 Pandemic Mistakes We Keep Repeating – The Atlantic (a few articles per month are free)
Editorial | Twenty Lessons from 2020: With a Focus on the ICU Perspective
28 Feb, 2021 | 21:44h | UTCTwenty Lessons from 2020: With a Focus on the ICU Perspective – ICU Management & Practice
2 Case Series and Guidance| Lymphadenopathy in COVID-19 Vaccine Recipients
28 Feb, 2021 | 21:42h | UTCCase series: Lymphadenopathy in COVID-19 Vaccine Recipients: Diagnostic Dilemma in Oncology Patients – Radiology
Related case series in women without cancer: Coronavirus Disease (COVID-19) Vaccination Associated Axillary Adenopathy: Imaging Findings and Follow-Up Recommendations in 23 Women – American Journal of Roentgenology
Related guidance 1: Multidisciplinary Recommendations Regarding Post-Vaccine Adenopathy and Radiologic Imaging: Radiology Scientific Expert Panel – Radiology
Related guidance 2: Mitigating the Impact of Coronavirus Disease (COVID-19) Vaccinations on Patients Undergoing Breast Imaging Examinations: A Pragmatic Approach – American Journal of Roentgenology AND Commentary: What to do when a mammogram shows swollen lymph nodes in women just vaccinated for COVID – Massachusetts General Hospital
Commentary: COVID-19 vaccine affects imaging results, researchers warn – AuntMinnie (free registration required)
Targeted spraying to prevent malaria in low-transmission setting halves cost of current practice
28 Feb, 2021 | 21:25h | UTCNews release: Targeted spraying to prevent malaria in low-transmission setting halves cost of current practice – Wits University
Commentary on Twitter
New paper from @davidjbath @CatKPitt and colleagues
@LSHTM_CHIL @LSHTM_malariaTargeting spraying for malaria control is safe, less costly, and cost-effective compared with standard spraying
With low incidence, these funds could be spent elsewhere🦟https://t.co/OCb9qhqBCX https://t.co/a0sD4uhymo
— Global Health Economics Centre (@LSHTM_GHECO) February 26, 2021
Turning houses into ‘lethal mosquito lures’ nearly halves incidence of malaria in children
28 Feb, 2021 | 21:26h | UTC
Commentary on Twitter (thread – click for more)
https://twitter.com/EDSternberg/status/1365083598538362882
Clinical Update: Enteric Fever
28 Feb, 2021 | 21:02h | UTCEnteric fever – The BMJ (free for a limited period)
Commentary on Twitter
Diagnosis of enteric fever is complicated as symptoms overlap with other causes of fever and early investigations are inconclusive. Here's what you need to know about its presentation, diagnosis, and treatment #BMJEducationhttps://t.co/1mvbNb7peS pic.twitter.com/Z7YxngHanl
— The BMJ (@bmj_latest) February 28, 2021
M-A: Risk predictors of progression to severe disease during the febrile phase of dengue
28 Feb, 2021 | 20:57h | UTC
U.S. Guidelines panel recommendation for long-acting injectable antiretroviral regimen in adults and adolescents with HIV
28 Feb, 2021 | 20:34h | UTCWhat’s New in the Guidelines? Panel’s Recommendation for Long-Acting Injectable Cabotegravir and Rilpivirine in Persons with HIV
CDC studies on superspreading events at fitness facilities
26 Feb, 2021 | 08:44h | UTCCommentaries: Going maskless is a key factor in Covid-19 outbreaks at gyms, studies say – CNN AND A Chicago gym saw dozens of COVID-19 cases after infected people attended HIIT classes without masks – Insider
Conflicting results from 2 randomized trials testing Tocilizumab for Covid-19
26 Feb, 2021 | 08:48h | UTC
Commentary on Twitter
Why do 2 randomized trials of tocilizumab, an interleukin-6 blocker, for severe covid-19, have opposite results?
Today @NEJMhttps://t.co/g8LCrhhpLyhttps://t.co/BcN3wOwsl0 pic.twitter.com/sLrQUYI1pf— Eric Topol (@EricTopol) February 25, 2021
PRO-CON Debate: Are Carbapenems necessary for all infections caused by ceftriaxone-resistant Enterobacterales?
28 Feb, 2021 | 20:43h | UTCEditorial: Navigating treatment approaches for presumed ESBL-producing infections
Commentary on Twitter (thread – click for more)
🔥NEW🔥 PRO-CON Debate on the role of carbapenems in infections caused by Enterobacterales resistant to ceftriaxone. #AMR @BSACandJAC @IDdocAdi @ABsteward
— JAC-AMR (@jac_amr) February 24, 2021
WHO Report: Preparing for Long COVID 2021
26 Feb, 2021 | 08:46h | UTCIn the wake of the pandemic: preparing for Long COVID (2021) – World Health Organization
Commentaries: Long COVID sufferer still has disease’s debilitating symptoms nearly a year after first falling ill – EuroNews AND Debilitating ‘long-COVID’ may have severe health, social impacts: WHO – Reuters
Related: Dr. Fauci says new data suggests ‘long’ Covid symptoms can last up to 9 months – CNBC
New protocol tested SARS-CoV-2 positivity on day 9 among quarantined student contacts of confirmed cases, resulting in safe reduction in loss of instructional time
26 Feb, 2021 | 08:42h | UTCCommentary: Is the CDC 10-day COVID-19 quarantine guideline enough? – News Medical
Commentary on Twitter
In this study of a 9-day testing protocol for student contacts of confirmed #COVID19 cases in 1 Florida county, a reduction in loss of instructional time was found that was less than what would have occurred with 14-day quarantine https://t.co/YPft2oAvYk
— JAMA (@JAMA_current) February 19, 2021
Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19
26 Feb, 2021 | 08:43h | UTCCommentary: Studies help discern severe COVID from related kids’ syndrome – CIDRAP
Commentary on Twitter
In this case series using national MIS-C registry data, kids w MIS-C were younger (6-12 y), more likely to be non-Hispanic Black, & have severe CV or mucocutaneous involvement and more extreme inflammation vs kids w severe #COVID19 https://t.co/jmCCDPXLmf @BostonChildrens
— JAMA (@JAMA_current) February 25, 2021
Real-world data confirms Pfizer-BioNTech vaccine effectiveness
25 Feb, 2021 | 09:09h | UTCAudio Interview: The Real-World Effectiveness of Covid-19 Vaccination – New England Journal of Medicine
Commentaries: Real-world trial of Pfizer COVID vaccine finds high 2-dose, good 1-dose protection – CIDRAP AND Pfizer-BioNTech vaccine performs as well in the real world as in clinical trials, new study concludes – STAT AND In boost for COVID-19 battle, Pfizer vaccine found 94% effective in real world – Reuters AND Expert reaction to NEJM paper on Pfizer-BioNTech vaccine roll-out in Israel and COVID-19 outcomes – Science Media Centre
Commentary on Twitter (thread – click for more)
1/
We've just confirmed the effectiveness of the Pfizer-BioNTech vaccine outside of randomized trials.Details @NEJM: https://t.co/POgXK8owvM
Yes, great news, but let's talk about methodological issues that arise when using #observational data to estimate vaccine effectiveness.
— Miguel Hernán (@_MiguelHernan) February 24, 2021
Study finds increased COVID-19 mortality among adults with Down syndrome
26 Feb, 2021 | 08:39h | UTCCommentaries: Adults with Down syndrome 3 times more likely to die of COVID, study finds – CIDRAP AND International study finds increased COVID-19 mortality among adults with Down syndrome – Case Western Reserve University
Related: COVID-19 is 10 times deadlier for people with Down syndrome, raising calls for early vaccination – Science (a few articles per month are free)
COVID-19 hospitalizations attributable to cardiometabolic conditions
26 Feb, 2021 | 08:40h | UTCCommentary: Study estimates two-thirds of COVID-19 hospitalizations due to four conditions – Tufts University
Commentary on Twitter
https://twitter.com/Dmozaffarian/status/1364993823370338312
Opinion – Catching COVID from surfaces is very unlikely. So perhaps we can ease up on the disinfecting
26 Feb, 2021 | 08:38h | UTCRelated: Coronavirus is in the air — there’s too much focus on surfaces – Nature AND COVID-19 rarely spreads through surfaces. So why are we still deep cleaning? – Nature