Commentaries: Real-world trial of Pfizer COVID vaccine finds high 2-dose, good 1-dose protection – CIDRAP AND Pfizer-BioNTech vaccine performs as well in the real world as in clinical trials, new study concludes – STAT AND In boost for COVID-19 battle, Pfizer vaccine found 94% effective in real world – Reuters AND Expert reaction to NEJM paper on Pfizer-BioNTech vaccine roll-out in Israel and COVID-19 outcomes – Science Media Centre
Commentary on Twitter (thread – click for more)
We've just confirmed the effectiveness of the Pfizer-BioNTech vaccine outside of randomized trials.
Yes, great news, but let's talk about methodological issues that arise when using #observational data to estimate vaccine effectiveness.
— Miguel Hernán (@_MiguelHernan) February 24, 2021