Infectious Diseases (all articles)
Perspective | The four most urgent questions about long COVID.
10 Jun, 2021 | 09:47h | UTCThe four most urgent questions about long COVID – Nature
Perspective | Identifying and tracking SARS-CoV-2 variants — a challenge and an opportunity.
10 Jun, 2021 | 09:43h | UTC
COVID nails: these changes to your fingernails may show you’ve had coronavirus.
10 Jun, 2021 | 09:42h | UTCCOVID nails: these changes to your fingernails may show you’ve had coronavirus – The Conversation
WHO issues new guidance for research on genetically modified mosquitoes to fight malaria and other vector-borne diseases.
10 Jun, 2021 | 09:38h | UTCGuideline: The guidance framework for testing genetically modified mosquitoes – World Health Organization
Cluster-randomized trial: Wolbachia-infected Aedes aegypti (less susceptible than wild-type A. aegypti to dengue virus infection) deployments reduced the incidence of symptomatic dengue and resulted in fewer hospitalizations.
10 Jun, 2021 | 09:40h | UTCCommentary: ‘Miraculous’ mosquito hack cuts dengue by 77% – BBC
Video Abstract: Efficacy of Wolbachia-infected Mosquito Deployments for the Control of Dengue
Perspective | Uncertain effects of the pandemic on respiratory viruses.
10 Jun, 2021 | 09:41h | UTCUncertain effects of the pandemic on respiratory viruses – Science
Commentary on Twitter
A new #SciencePerspective argues that expanded genomic and clinical surveillance is needed to best understand the spread of respiratory viruses in a post-#COVID19 world.
🔎 Learn more: https://t.co/1rw3q76PZc pic.twitter.com/eyb4LDrfG7
— Science Magazine (@ScienceMagazine) June 9, 2021
[Preprint] RECOVERY trial finds aspirin does not improve survival for patients hospitalized with COVID-19.
9 Jun, 2021 | 08:28h | UTCNews Release: RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19 – University of Oxford
Original Study: Aspirin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial – medRxiv
Commentary on Twitter (thread – click for more)
RECOVERY Pre-print: Aspirin
14,892 patients randomised to aspirin vs. usual care
– no impact on all-cause mortality (17% vs. 17%)
– similar results in all pre-specified subgroupshttps://t.co/ay5Xg4GBVD pic.twitter.com/aNJ09RTTOa— Martin Landray (@MartinLandray) June 8, 2021
COVID-19 Imaging: What we know now and what remains unknown.
9 Jun, 2021 | 08:27h | UTCCOVID-19 Imaging: What We Know Now and What Remains Unknown – Radiology
Perspective | How COVID changed science.
9 Jun, 2021 | 08:24h | UTCHow COVID Changed Science – Scientific American
Systematic review: Frequency, signs and symptoms, and criteria adopted for long COVID-19.
9 Jun, 2021 | 08:22h | UTC
China to offer COVID-19 vaccine to children as young as three.
9 Jun, 2021 | 08:26h | UTCChina to offer COVID-19 vaccine to children as young as three – MedicalXpress
See also: Sinovac says its vaccine is safe for children as young as 3 – Associated Press
Summary | WHO recommendations on the treatment of drug-resistant tuberculosis, 2020 update.
9 Jun, 2021 | 08:12h | UTCOriginal Guideline: WHO Consolidated Guidelines on Tuberculosis, Module 4: Treatment – Drug-Resistant Tuberculosis Treatment
Commentary on Twitter
🆕💥💥@ERSpublications
WHO guidelines on the treatment of drug-resistant TB contain the latest recommendations on shorter or longer all oral treatment regimens for patients with drug-resistant TB, including the medicines to be used& supportive measures https://t.co/qeeftVYdYN pic.twitter.com/4NKNNjz3Gh— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 8, 2021
No health issues in babies whose moms got flu vaccine while pregnant.
9 Jun, 2021 | 08:17h | UTCNo health issues in babies whose moms got flu vaccine while pregnant – CIDRAP
Original study: Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes – JAMA (free for a limited period)
Editorial: Realizing the Potential of Maternal Influenza Vaccination (free for a limited period)
Commentary on Twitter
https://twitter.com/ericbenchimol/status/1402307635240706048
In youth, COVID-19 causes more complications than flu; fatality is rare.
9 Jun, 2021 | 08:23h | UTCOriginal study: 30-Day Outcomes of Children and Adolescents With COVID-19: An International Experience – Pediatrics
Short review: Neurological complications of COVID-19.
8 Jun, 2021 | 09:36h | UTCNeurological complications of COVID-19 – Intensive Care Medicine
Commentary on Twitter
NeuroCOVID potential mechanism(s)?
🧠 #COVID19 neuro-complications
🧠 direct neuroinvasion
🧠 inflammatory/autoimmune
🧠 vascular
+
🧠 #ICU complications
🧠 drugs toxicity/side effects
🧠 PICS/PACS & PTSD
Challenging to identify/diagnose: strictly monitor! https://t.co/0YlAoanUFo pic.twitter.com/unM0SWFR7L— Intensive Care Medicine (@yourICM) June 7, 2021
Underlying medical conditions associated with severe COVID-19 illness among children – the strongest risk factors for hospitalization were chronic and complex chronic diseases, type 1 diabetes, and obesity.
8 Jun, 2021 | 09:37h | UTCCommentaries: Underlying illness, respiratory infection raise risk for severe COVID in kids – CIDRAP AND COVID-19 in Children—Not Just Little Adults – JAMA Network Open
Commentary on Twitter
This cross-sectional study found a higher risk of severe #COVID19 illness among children with medical complexity and certain underlying conditions, such as type 1 diabetes, cardiac and circulatory congenital anomalies, and obesity. https://t.co/ifq1Ao0HKS
— JAMA Network Open (@JAMANetworkOpen) June 7, 2021
Are SARS-CoV-2 Human Challenge Trials Ethical? – “A clinical trial is underway in the UK in which young, healthy participants are exposed deliberately to SARS-CoV-2 to assess the viral inoculum needed to produce an infection and to test vaccine efficacy”.
8 Jun, 2021 | 09:29h | UTCAre SARS-CoV-2 Human Challenge Trials Ethical? – JAMA Internal Medicine
Related: World’s first coronavirus “Human Challenge” study receives ethics approval in the UK (several texts on the subject)
Commentary on Twitter
I am not convinced of #SARSCoV2 #ChallengeTrials. You should not pay volunteers. If things go wrong, there is no effective treatment. What will be learnt from mild disease, when you are interested in severe disease? #COVID19 #Covid #Corona #coronavirushttps://t.co/JjXDJDfOl2
— Martin Michaelis (@MartMichaelis) June 8, 2021
The “Black Fungus” in India: The Emerging Syndemic of COVID-19–Associated Mucormycosis – careful use of antibiotics and corticosteroids and closely monitoring blood glucose levels are some of the strategies suggested by the authors.
8 Jun, 2021 | 09:34h | UTC
Multicenter Epidemiologic Study of Coronavirus Disease–Associated Mucormycosis, India – Uncontrolled diabetes mellitus was the most common underlying disease; improper glucocorticoid use was independently associated with the disease.
8 Jun, 2021 | 09:33h | UTCCommentary: COVID19: Secondary Infections Still a Big Challenge in India – News Click
Commentary on Twitter
New study from India on mucormycosis
– COVID-19 has led to increases in mucormycosis, partly from inappropriate steroid use
– Uncontrolled diabetes was the most common underlying disease
Better diabetes care & rational steroid use are key!https://t.co/Wv8kCyTDtK pic.twitter.com/KK78BKg2Xf
— Madhu Pai, MD, PhD (@paimadhu) June 7, 2021
Report: 376,000 people in UK have had long Covid symptoms for at least a year.
8 Jun, 2021 | 09:27h | UTC376,000 people in UK have had long Covid symptoms for at least a year – ONS – The Guardian
Original report: Prevalence of ongoing symptoms following coronavirus (COVID-19) infection in the UK: 4 June 2021 – Office for National Statistics
Practice Pointer | Mask related acne (“maskne”) and other facial dermatoses.
8 Jun, 2021 | 09:24h | UTCMask related acne (“maskne”) and other facial dermatoses – The BMJ
Commentary on Twitter
The term “maskne” has become increasingly popular during the pandemic, particularly in the media.
This #BMJInfographic presents common distributions that can be used as a starting point for assessment @will_s_t https://t.co/mKQUaN3PYY pic.twitter.com/OCBuFxiY9s
— The BMJ (@bmj_latest) June 7, 2021
Diagnostic value of cutaneous manifestation of SARS-CoV-2 infection – there was a significant association between skin rashes and a positive swab test result (odds ratio 1.67).
8 Jun, 2021 | 09:26h | UTCDiagnostic value of cutaneous manifestation of SARS-CoV-2 infection – British Journal of Dermatology
Time-to-positivity in bloodstream infection is not a prognostic marker for mortality: analysis of a prospective multicenter randomized control trial.
8 Jun, 2021 | 09:21h | UTC
Commentary on Twitter
🆕💥Analysis Data from RAPIDO RCT
Time to positivity is not associated with mortality, except in Candida spp (longer times associated with worse outcomes), and possibly in Streptococci (shorter times associated with worse outcomes) #IDTwitter #medtwitter https://t.co/v17uT8j7u9— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) June 7, 2021
RCT: In patients hospitalized with Covid-19 with elevated D-Dimer, a full-dose anticoagulation strategy based on rivaroxaban (full-dose heparins in unstable patients) + rivaroxaban to day 30 was not better than prophylactic anticoagulation and increased bleeding risk.
7 Jun, 2021 | 00:01h | UTC
Commentary on Twitter
https://twitter.com/RenatoDLopes1/status/1400962037610582026
Six months of COVID vaccines: what 1.7 billion doses have taught scientists.
6 Jun, 2021 | 23:57h | UTCSix months of COVID vaccines: what 1.7 billion doses have taught scientists – Nature
See also: Coronavirus (COVID-19) Vaccinations – Our World in Data
Related commentary on Twitter
• To administer the first half a billion vaccines took 113 days
• The second half a billion 30 days
• The third half a billion 23 days
• And the fourth half a billion were administered in the last 16 daysWe keep on counting on @OurWorldInData here: https://t.co/7lOyDamxxx pic.twitter.com/Pg7OPJxliI
— Max Roser (@MaxCRoser) June 4, 2021