Covid-19
M-A: The collateral damage of COVID-19 to cardiovascular services.
1 Jun, 2022 | 11:56h | UTCNews Release: COVID-19’s toll on global cardiac services – University of Leeds
Commentary: COVID-19 severely disrupted global cardiac care, increasing deaths – CIDRAP
Commentary on Twitter
Conclusions from a recent meta-analysis now in EHJ online. "There was substantial global collateral CV damage during the COVID-19 pandemic with disparity in severity by country income classification."#COVID19 #EHJhttps://t.co/jb8bFDL4JP pic.twitter.com/g3oQSP9gFg
— EHJ Editor-in-Chief (@ehj_ed) May 31, 2022
Network Meta-Analysis: Effectiveness of heterologous and homologous covid-19 vaccine regimens.
1 Jun, 2022 | 12:00h | UTCNews Release: Three doses of the same or mixed covid jabs work equally well against infections – BMJ
Commentary: Three jabs best for preventing Covid infections, global analysis finds – The Guardian
Systematic Review: SARS-CoV-2 saliva testing using RT-PCR.
1 Jun, 2022 | 11:42h | UTC
Systematic Review: Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID‐19.
31 May, 2022 | 11:40h | UTCSummary: How accurate are symptoms and medical examination to diagnose COVID-19? – Cochrane Library
Commentary on Twitter (thread – click for more)
UPDATE JUST PUBLISHED – How accurate are symptoms & medical examination to diagnose #COVID19?
📚@Cochrane_IDG authors looked at the evidence from 42 studies with 52,608 participants in this review.
➡️https://t.co/pbP9BX5Xkm 1/5 pic.twitter.com/bjfb6yVTGg— The Cochrane Library (@CochraneLibrary) May 20, 2022
An early warning system for emerging SARS-CoV-2 variants.
31 May, 2022 | 11:34h | UTCAn early warning system for emerging SARS-CoV-2 variants – Nature Medicine
Commentary on Twitter
🆕@NatureMedicine
"The pandemic is not over, and #SARSCoV2 is spreading at a high level globally. Now is the time to enhance global sequencing capacities, focusing on widening coverage to include previous geographical and population blind spots"https://t.co/yL2xisDH0r@lsubissi pic.twitter.com/xip3MR762v— Eric Topol (@EricTopol) May 30, 2022
Opinion: COVID-19 in 2022—The beginning of the end or the end of the beginning?
31 May, 2022 | 11:32h | UTCCOVID-19 in 2022—The Beginning of the End or the End of the Beginning? – JAMA
Analysis/Opinion: The unintended consequences of COVID-19 vaccine policy: “why mandates, passports and restrictions may cause more harm than good”.
30 May, 2022 | 11:46h | UTC
Commentary on Twitter (thread – click for more)
📢 Our paper on COVID-19 vaccine policy has been published💉🦠
We discuss 12 unintended consequences of mandates and passports across society
& argue that pandemic vaccine policies have caused more social harm than good
Read the paper: https://t.co/TeyTki0nWI pic.twitter.com/BRJQRURbUc
— Kevin Bardosh (@KevinBardosh) May 26, 2022
Right ventricular failure is strongly associated with mortality in patients with moderate-to-severe COVID-19-related ARDS and appears related to respiratory worsening.
27 May, 2022 | 12:17h | UTC
Commentary on Twitter
RV failure in moderate-to-severe #COVID19 #ARDS
➡️strong predictor of mortality
➡️significant worsening of PaO2/FiO2, PaCO2 & ventilatory ratio (⬆️ pulm vasoconstriction) & ⬆️ driving P could contribute#POCUS mandatory especially if resp deterioration.
📎 https://t.co/OE56BuxeWz pic.twitter.com/dNIeo1yHcP— Intensive Care Medicine (@yourICM) May 16, 2022
Pivot into COVID-19 research eases as publishing surge starts to level off – Researchers who jumped into the field from distant disciplines published lower impact work, study finds.
27 May, 2022 | 12:18h | UTCPivot into COVID-19 research eases as publishing surge starts to level off – Science
Covid-19: Vaccine effectiveness wanes more rapidly for cancer patients, study finds.
27 May, 2022 | 12:04h | UTCCommentary: Covid-19: Vaccine effectiveness wanes more rapidly for cancer patients, study finds – The BMJ
A comprehensive evaluation of COVID-19 policies and outcomes in 50 countries and territories.
27 May, 2022 | 12:11h | UTC
Cohort Study: Protection and waning of natural and hybrid immunity to SARS-CoV-2.
26 May, 2022 | 11:07h | UTCProtection and Waning of Natural and Hybrid Immunity to SARS-CoV-2 – New England Journal of Medicine
Editorial: Audio Interview: Waning Immunity against Covid-19
Commentary on Twitter
Protection against SARS-CoV-2 waned over time in both vaccinated and previously infected persons; an additional vaccine dose restored protection, find investigators from Israel. https://t.co/617uBmWu8l pic.twitter.com/yiDnBbCuQ5
— NEJM (@NEJM) May 25, 2022
Study Commentary: Long COVID risk falls only slightly after vaccination, huge study shows.
26 May, 2022 | 11:25h | UTCCommentary: Long COVID risk falls only slightly after vaccination, huge study shows – Nature
Original Study: Long COVID after breakthrough SARS-CoV-2 infection – Nature Medicine
Commentary from the author on Twitter (thread – click for more)
The latest from our team in @NatureMedicine
Does vaccination protect from #LongCovid?
Vaccines modestly reduce but do not eliminate risk of Long Covid @VAResearch @vahsrd @WUSTLmed @WUSTLnews @VREFSTL@Biostayan @BCBowe https://t.co/UEexmL8svS
A thread 🧵
— Ziyad Al-Aly, MD (@zalaly) May 25, 2022
Cohort Study: Trajectory of long covid symptoms after covid-19 vaccination.
26 May, 2022 | 11:23h | UTCTrajectory of long covid symptoms after covid-19 vaccination: community based cohort study – The BMJ
Editorial: Are vaccines a potential treatment for long covid? – The BMJ
News Release: Vaccination after SARS-CoV-2 infection linked to a decrease in long covid symptoms – BMJ Newsroom
Commentary on Twitter
LONG COVID: Number of well controlled studies (controls means comparison group of 1) unvaccinated and 2) those who have never had COVID) that show vaccination works to reduce or eliminate long COVID symptoms increasing. BMJ below + biggest from Israel herehttps://t.co/jtZ6aoDmFA https://t.co/n5oDs0Zxe9
— Monica Gandhi MD, MPH (@MonicaGandhi9) May 19, 2022
Test-negative, case–control study: effectiveness of homologous and heterologous Covid-19 boosters against Omicron.
26 May, 2022 | 10:59h | UTC
Effectiveness of CoronaVac in children 3 to 5 years during the SARS-CoV-2 Omicron outbreak in Chile.
25 May, 2022 | 11:42h | UTC
RCT: Baricitinib vs. dexamethasone for adults hospitalized with COVID-19.
25 May, 2022 | 11:38h | UTC
Commentary on Twitter
💥Just Out
ACTT-4 Trial👉First Double Placebo-Controlled Double-Blind Randomized-Stratified Head-to-Head#DEXAMETHASONE vs #BARICITINIB for hospitalized pts w/#COVID19 Low/High-Flow/NIV
Relevant👉Patient Care/Public Health/Guidelines
Our results
👇https://t.co/4Tmue7HK7V
🧵1/4 pic.twitter.com/aF1Y7BAdu3— Andre Kalil, MD MPH (@DrAndreKalil) May 24, 2022
Short term, relative effectiveness of four doses versus three doses of BNT162b2 vaccine in people aged 60 years and older in Israel: retrospective, test negative, case-control study.
25 May, 2022 | 11:34h | UTCRelated recommendations:
NICE rapid guideline update on the management of Covid-19.
23 May, 2022 | 01:56h | UTCCOVID-19 rapid guideline: managing COVID-19 – National Institute for Health and Care Excellence
RCT: Safety and immunogenicity of heterologous boost immunization with an orally administered aerosolized Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults.
23 May, 2022 | 01:54h | UTC
Commentary on Twitter
Mix-and-match typically refers to different shots. Here's a randomized trial of shots and an oral vaccine that ameliorates the immune responsehttps://t.co/FFWHEwS37Y @LancetRespirMed pic.twitter.com/JZyvrxCalS
— Eric Topol (@EricTopol) May 21, 2022
RCT: High-flow nasal oxygen is not beneficial for patients with COVID-19 pneumonia and mild hypoxemia.
23 May, 2022 | 01:51h | UTC
WHO validates 11th vaccine for COVID-19.
20 May, 2022 | 11:16h | UTCWHO validates 11th vaccine for COVID-19 – World Health Organization
Commentary on Twitter
WHO issued an emergency use listing for CONVIDECIA, a vaccine manufactured by CanSino Biologics, China, adding to a growing portfolio of #COVID19 vaccines validated by WHO https://t.co/QdpHiasT2p pic.twitter.com/2B54FwiNDl
— World Health Organization (WHO) (@WHO) May 19, 2022
Covid-19: Second boosters may benefit at-risk groups but have “minimal” impact for others, says WHO.
20 May, 2022 | 11:08h | UTCOriginal Statement: Interim statement on the use of additional booster doses of Emergency Use Listed mRNA vaccines against COVID-19 – World Health Organization
Related recommendations:
COVID-19 evidence: a Cochrane round-up.
20 May, 2022 | 11:14h | UTCCOVID-19 evidence: a Cochrane round-up – Cochrane Library
Systematic Review: Thoracic imaging tests for the diagnosis of COVID‐19.
20 May, 2022 | 11:13h | UTCThoracic imaging tests for the diagnosis of COVID‐19 – Cochrane Library
Summary: How accurate is chest imaging for diagnosing COVID-19? – Cochrane Library