RCT: Safety and immunogenicity of heterologous boost immunization with an orally administered aerosolized Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults.

Safety and immunogenicity of heterologous boost immunisation with an orally administered aerosolised Ad5-nCoV after two-dose priming with an inactivated SARS-CoV-2 vaccine in Chinese adults: a randomised, open-label, single-centre trial – The Lancet Respiratory Medicine

Commentary on Twitter

Mix-and-match typically refers to different shots. Here's a randomized trial of shots and an oral vaccine that ameliorates the immune responsehttps://t.co/FFWHEwS37Y @LancetRespirMed pic.twitter.com/JZyvrxCalS

— Eric Topol (@EricTopol) May 21, 2022