Antibiotic Stewardship
Cohort Study: Patient factors associated with appendectomy within 30 days of initiating antibiotic treatment for appendicitis – the presence of an appendicolith was associated with a nearly 2-fold increased risk of undergoing appendectomy within 30 days.
13 Jan, 2022 | 08:39h | UTCPatient Factors Associated With Appendectomy Within 30 Days of Initiating Antibiotic Treatment for Appendicitis – JAMA Surgery (free for a limited period)
Invited commentary: Appendicoliths, Antibiotic Treatment Failure, and Appendectomy—Is the Glass Half Full or Half Empty? – JAMA Surgery
The Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin.
13 Jan, 2022 | 08:17h | UTCThe Antifungal Pipeline: Fosmanogepix, Ibrexafungerp, Olorofim, Opelconazole, and Rezafungin – Drugs
Cohort Study: In preterm premature rupture of membranes at 24-31 weeks, antibiotic prophylaxis based on third-generation cephalosporin may be associated with improved perinatal outcomes compared to amoxicillin.
13 Jan, 2022 | 08:10h | UTCAntibiotic prophylaxis in preterm premature rupture of membranes at 24-31 weeks’ gestation: perinatal and 2-year outcomes in the EPIPAGE-2 cohort – BJOG (link to abstract – $ for full-text)
Systematic Review: First-generation cephalosporins for the treatment of complicated upper urinary tract infection in adults.
11 Jan, 2022 | 02:23h | UTC
Commentary on Twitter
Interesting! Why not?
🆕💥Systematic literature review First-generation cephalosporins mainly Cefazolin and one study Cefadroxil for the treatment of complicated upper urinary tract infection in adults
Comparators mainly 3d G
Old studies
No meta-analysis https://t.co/EHamKpfKZQ— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) January 10, 2022
Systematic Review: The effectiveness and safety of treatments for recurrent vulvovaginal candidiasis.
11 Jan, 2022 | 02:24h | UTCTreatment for recurrent vulvovaginal candidiasis (thrush) – Cochrane Library
Cohort Study: Ciprofloxacin exposure during pregnancy was not associated with miscarriage or major malformations in a nationwide study from Denmark.
11 Jan, 2022 | 02:08h | UTCCiprofloxacin exposure and adverse pregnancy outcomes: a Danish nationwide cohort study – BJOG (link to abstract – $ for full-text)
Guideline: Prevention, diagnosis, and management of post-surgical mediastinitis in adults.
17 Dec, 2021 | 08:41h | UTC
Year In Review: Top Non-COVID Infectious Diseases Articles Of 2021.
17 Dec, 2021 | 08:36h | UTCYear In Review: Top Non-COVID Infectious Diseases Articles Of 2021 – IDStewardship
Commentary on Twitter
🔥🔥NEW 🔥🔥
My new post a great collaboration w the amazing @IDstewardship
Year In Review: Top✨ Non-COVID Infectious Diseases Articles Of 2021
18 high quality 🆔 RCTs
6 RCTs @NEJM#Shorterisbetter #IDTwitter #MedEd #TwitteRx #ASPchat #SoMeDocs
Others🤔https://t.co/wJtdjYJ0Gf pic.twitter.com/ugILKX5RQO— Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 (@ABsteward) December 17, 2021
Recommendations for antibiotic selection for severe nosocomial infections.
16 Dec, 2021 | 09:40h | UTC
Antibiotics in critically ill children—a narrative review on different aspects of a rational approach.
16 Dec, 2021 | 08:53h | UTC
Expert consensus and practical guidance: A global perspective on improving patient care in uncomplicated urinary tract infection.
15 Dec, 2021 | 08:33h | UTC
Review: Diagnosis and management of acute appendicitis in adults.
15 Dec, 2021 | 08:28h | UTCDiagnosis and Management of Acute Appendicitis in Adults: A Review – JAMA (free for a limited period)
Author Interview: Current Management of Acute Appendicitis: Antibiotics or Surgical Intervention
Commentary: Antibiotics can be first-line therapy for uncomplicated appendicitis cases – Duke University Medical Center
Infectious diseases learning pearls from inpatient ID consults.
15 Dec, 2021 | 08:22h | UTCID Learning Units from Inpatient ID Consults – HIV and ID Observations
Retrospective study: antimicrobial susceptibility profiles among neonatal early-onset sepsis (EOS) pathogens – “The vast majority of contemporary EOS pathogens are susceptible to the combination of ampicillin and gentamicin”.
14 Dec, 2021 | 08:46h | UTC
Commentary on Twitter
Are bacteria responsible for early-onset sepsis susceptible to empiric antibiotic therapy used in NICU?
A new @NICHD_NIH study by @dus10flan published in @PIDJournal #neoEBM #EBNEOAlertshttps://t.co/6HJf4ZgAGa pic.twitter.com/pGMfbj3DQ6
— Evidence-Based Neo (@EBNEO) December 13, 2021
Short Review: Lymphogranuloma venereum.
14 Dec, 2021 | 08:42h | UTCLymphogranuloma venereum – Canadian Medical Association Journal
Systematic Review: Antibiotics for adults and children with sore throats.
10 Dec, 2021 | 10:02h | UTCSummary: Antibiotics for adults and children with sore throats – Cochrane Library
Original Research: Antibiotics for treatment of sore throat in children and adults – Cochrane Library
IDSA Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.
7 Dec, 2021 | 08:49h | UTC
RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.
7 Dec, 2021 | 08:37h | UTC
Clinical Review: Management of pneumonia in critically ill patients.
7 Dec, 2021 | 08:41h | UTCManagement of pneumonia in critically ill patients – The BMJ
Pictorial Review: Spinal disorders mimicking infection.
5 Dec, 2021 | 23:10h | UTCSpinal disorders mimicking infection – Insights into Imaging
Review: Interventions to optimize antimicrobial stewardship.
3 Dec, 2021 | 10:11h | UTC
Review: COVID-19-associated Invasive Fungal Infection.
24 Nov, 2021 | 08:48h | UTCCOVID-19-associated Invasive Fungal Infection – Open Forum Infectious Diseases
Related:
Consensus Guideline: Defining and managing COVID-19-associated pulmonary aspergillosis
Bacterial and fungal superinfections in critically ill patients with COVID-19
Invasive Fungal Disease complicating COVID-19: when it rains it pours
A national strategy to diagnose COVID-19 associated invasive fungal disease in the ICU
Epidemiology of invasive pulmonary aspergillosis among COVID-19 intubated patients
Commentary on Twitter
A new article in OFID reviews COVID-19-associated fungal infections and addresses gaps in knowledge relating to the epidemiology, diagnosis and management of these infections: https://t.co/JIkkW70zHI#IDSAJournals #OpenForumInfectDis @PaulSaxMD @DrJLi @jobadd @DrPappasID pic.twitter.com/bPmFdKkjmb
— IDSA (@IDSAInfo) November 21, 2021
IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
23 Nov, 2021 | 08:45h | UTC
Commentary on Twitter
IDSA has released NEW guidance on treating infections caused by three of the most common drug-resistant pathogens:
• AmpC-E
• CRAB
• S. maltophiliaGuidelines: https://t.co/gjxEZcxtmy
Press release: https://t.co/ulorKCmvQ4#IDSAGuidelines #WAAW21 pic.twitter.com/Wy7uBaq2DN— IDSA (@IDSAInfo) November 22, 2021
Antibiotic Awareness: a round-up of Cochrane evidence.
23 Nov, 2021 | 08:23h | UTCAntibiotic Awareness: a round-up of Cochrane evidence – Cochrane Library
Commentary on Twitter
@CochraneUK – excellent resources and collection of antibiotic evidence review. #tldr
Azithro doesn’t work for COVID; procalcitonin reduces antibiotic use effectively; short course durations have similar outcomes to long; & so much more— Susan Hopkins (@SMHopkins) November 21, 2021
Recent updates in antimicrobial stewardship in outpatient parenteral antimicrobial therapy.
23 Nov, 2021 | 08:15h | UTC


