Antibiotic Stewardship
Recommendations for antibiotic selection for severe nosocomial infections.
16 Dec, 2021 | 09:40h | UTC
Antibiotics in critically ill children—a narrative review on different aspects of a rational approach.
16 Dec, 2021 | 08:53h | UTC
Expert consensus and practical guidance: A global perspective on improving patient care in uncomplicated urinary tract infection.
15 Dec, 2021 | 08:33h | UTC
Review: Diagnosis and management of acute appendicitis in adults.
15 Dec, 2021 | 08:28h | UTCDiagnosis and Management of Acute Appendicitis in Adults: A Review – JAMA (free for a limited period)
Author Interview: Current Management of Acute Appendicitis: Antibiotics or Surgical Intervention
Commentary: Antibiotics can be first-line therapy for uncomplicated appendicitis cases – Duke University Medical Center
Infectious diseases learning pearls from inpatient ID consults.
15 Dec, 2021 | 08:22h | UTCID Learning Units from Inpatient ID Consults – HIV and ID Observations
Retrospective study: antimicrobial susceptibility profiles among neonatal early-onset sepsis (EOS) pathogens – “The vast majority of contemporary EOS pathogens are susceptible to the combination of ampicillin and gentamicin”.
14 Dec, 2021 | 08:46h | UTC
Commentary on Twitter
Are bacteria responsible for early-onset sepsis susceptible to empiric antibiotic therapy used in NICU?
A new @NICHD_NIH study by @dus10flan published in @PIDJournal #neoEBM #EBNEOAlertshttps://t.co/6HJf4ZgAGa pic.twitter.com/pGMfbj3DQ6
— Evidence-Based Neo (@EBNEO) December 13, 2021
Short Review: Lymphogranuloma venereum.
14 Dec, 2021 | 08:42h | UTCLymphogranuloma venereum – Canadian Medical Association Journal
Systematic Review: Antibiotics for adults and children with sore throats.
10 Dec, 2021 | 10:02h | UTCSummary: Antibiotics for adults and children with sore throats – Cochrane Library
Original Research: Antibiotics for treatment of sore throat in children and adults – Cochrane Library
IDSA Guidance on the Treatment of AmpC β-lactamase-Producing Enterobacterales, Carbapenem-Resistant Acinetobacter baumannii, and Stenotrophomonas maltophilia Infections.
7 Dec, 2021 | 08:49h | UTC
RCT: Maribavir for refractory Cytomegalovirus infections with or without resistance post-transplant.
7 Dec, 2021 | 08:37h | UTC
Clinical Review: Management of pneumonia in critically ill patients.
7 Dec, 2021 | 08:41h | UTCManagement of pneumonia in critically ill patients – The BMJ
Pictorial Review: Spinal disorders mimicking infection.
5 Dec, 2021 | 23:10h | UTCSpinal disorders mimicking infection – Insights into Imaging
Review: Interventions to optimize antimicrobial stewardship.
3 Dec, 2021 | 10:11h | UTC
Review: COVID-19-associated Invasive Fungal Infection.
24 Nov, 2021 | 08:48h | UTCCOVID-19-associated Invasive Fungal Infection – Open Forum Infectious Diseases
Related:
Consensus Guideline: Defining and managing COVID-19-associated pulmonary aspergillosis
Bacterial and fungal superinfections in critically ill patients with COVID-19
Invasive Fungal Disease complicating COVID-19: when it rains it pours
A national strategy to diagnose COVID-19 associated invasive fungal disease in the ICU
Epidemiology of invasive pulmonary aspergillosis among COVID-19 intubated patients
Commentary on Twitter
A new article in OFID reviews COVID-19-associated fungal infections and addresses gaps in knowledge relating to the epidemiology, diagnosis and management of these infections: https://t.co/JIkkW70zHI#IDSAJournals #OpenForumInfectDis @PaulSaxMD @DrJLi @jobadd @DrPappasID pic.twitter.com/bPmFdKkjmb
— IDSA (@IDSAInfo) November 21, 2021
IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.
23 Nov, 2021 | 08:45h | UTC
Commentary on Twitter
IDSA has released NEW guidance on treating infections caused by three of the most common drug-resistant pathogens:
• AmpC-E
• CRAB
• S. maltophiliaGuidelines: https://t.co/gjxEZcxtmy
Press release: https://t.co/ulorKCmvQ4#IDSAGuidelines #WAAW21 pic.twitter.com/Wy7uBaq2DN— IDSA (@IDSAInfo) November 22, 2021
Antibiotic Awareness: a round-up of Cochrane evidence.
23 Nov, 2021 | 08:23h | UTCAntibiotic Awareness: a round-up of Cochrane evidence – Cochrane Library
Commentary on Twitter
https://t.co/oVkKaj433K@CochraneUK – excellent resources and collection of antibiotic evidence review. #tldr
Azithro doesn’t work for COVID; procalcitonin reduces antibiotic use effectively; short course durations have similar outcomes to long; & so much more— Susan Hopkins (@SMHopkins) November 21, 2021
Recent updates in antimicrobial stewardship in outpatient parenteral antimicrobial therapy.
23 Nov, 2021 | 08:15h | UTC
M-A: Intravenous iron is associated with increased risk of infection when compared with oral iron or no iron, which must be balanced with the potential benefits of reducing blood transfusion requirements.
19 Nov, 2021 | 10:31h | UTCInvited Commentary: Intravenous Iron and Infection Risk—Still an Unanswered Question – JAMA Network Open
Commentary on Twitter
In this systematic review and meta-analysis, administration of intravenous iron was associated with an increased risk of infection. This risk must be balanced with the potential benefits of treating anemia and reducing blood transfusion requirements. https://t.co/XkNJKCk7M7
— JAMA Network Open (@JAMANetworkOpen) November 12, 2021
Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method.
12 Nov, 2021 | 10:41h | UTC
Commentary from the author on Twitter (thread – click for more)
Honoured to lead this Delphi on Infection Control in ICU for SARS-CoV-2 with global experts https://t.co/39NTHgfyZR @Drnasap @ElieAzoulay5 @jigidivatia @AlhazzaniW @NaomiHammond @criticcaredoc @YaseenarabiYa @Laura_Evans_206 @FlaviaSepsis @AndersPerner @jlvincen @TheLancetInfDis pic.twitter.com/RWw6vXcHb0
— Sheila Myatra (@SheilaMyatra) November 11, 2021
Estimating daily antibiotic harms: an umbrella review with individual study meta-analysis – “Each day of antibiotic therapy was associated with 4% increased odds of experiencing an adverse event”.
12 Nov, 2021 | 09:47h | UTC
Commentary on Twitter
Each additional day of antibiotic therapy is associated with measurable antibiotic harm, particularly adverse events
??? @CMIJournal @BRxAD et Al
Estimating daily antibiotic harms: an umbrella review with individual study meta-analysis #IDTwitter https://t.co/ERlUZ1ict6 pic.twitter.com/KOWU4PhSzK— Antibiotic Stewa®️x? Bassam Ghanem (@ABsteward) November 11, 2021
RCT: Among children with community-acquired pneumonia discharged within 48 hours from the ED or hospital, lower-dose outpatient oral amoxicillin was noninferior to a higher dose, and a 3-day duration course was noninferior to 7 days.
3 Nov, 2021 | 09:56h | UTCEffect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA (free for a limited period)
Related:
ACP Guidance: Appropriate Use of Short-Course Antibiotics in Common Infections
RCT: 7 days of antibiotic therapy as good as 14 days for afebrile men with urinary tract infection.
Commentary on Twitter
?Just published?
CAP-IT RCT
Children w CAP discharged from ED or hospital (w/in48 hrs)
lower-dose outpatient oral amoxicillin was noninferior to higher dose& 3d was noninferior to 7 d, w regard to need for Abx re-treatment @BradSpellberg table update ? https://t.co/VkxBmJaEeW pic.twitter.com/fKzpGp1XM7— Antibiotic Stewa®️x? Bassam Ghanem (@ABsteward) November 2, 2021
A comprehensive review of vascular complications in COVID-19.
2 Nov, 2021 | 03:01h | UTC
Short Review: Metronidazole-induced neurotoxicity.
2 Nov, 2021 | 02:41h | UTCMetronidazole-induced neurotoxicity – Canadian medical Association Journal
Commentary on Twitter
The ability of metronidazole to cause neurotoxicity is not widely appreciated. Here's our quick overview led by @DanicaQuickfall, just out in @CMAJ.
https://t.co/7sggYzCzGN pic.twitter.com/miW0trFuYv— David Juurlink (@DavidJuurlink) October 25, 2021
Review: How I manage a patient with MRSA bacteremia.
31 Oct, 2021 | 19:54h | UTCHow I manage a patient with MRSA bacteraemia – Clinical Microbiology and Infection
Systematic Review: Prophylactic antibiotics for preventing gram‐positive infections associated with long‐term central venous catheters in adults and children receiving treatment for cancer.
28 Oct, 2021 | 09:58h | UTC