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Antibiotic Stewardship

Review: Non-invasive testing and surrogate markers in invasive fungal diseases.

6 May, 2022 | 10:29h | UTC

Non-invasive Testing and Surrogate Markers in Invasive Fungal Diseases – Open Forum Infectious Diseases

 

Retrospective cohort study: Treatment outcome with penicillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bacteremia.

5 May, 2022 | 09:39h | UTC

Treatment outcome with penicillin G or cloxacillin in penicillin susceptible Staphylococcus aureus bacteraemia – A retrospective cohort study – International Journal of Antimicrobial Agents

 

Commentary on Twitter

 

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection.

4 May, 2022 | 10:36h | UTC

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection – Nature Communications

 

Commentary on Twitter (thread – click for more)

 

M-A: Risk factors for contracting invasive meningococcal disease and related mortality.

3 May, 2022 | 10:29h | UTC

Risk Factors for Contracting Invasive Meningococcal Disease and Related Mortality: A Systematic Literature Review and Meta-analysis – International Journal of Infectious Diseases

 

RCT: Extended vs. standard antibiotic course duration in children below 5 years of age hospitalized with community-acquired pneumonia in high-risk settings.

29 Apr, 2022 | 11:16h | UTC

Extended Versus Standard Antibiotic Course Duration in Children <5 Years of Age Hospitalized With Community-acquired Pneumonia in High-risk Settings: Four-week Outcomes of a Multicenter, Double-blind, Parallel, Superiority Randomized Controlled Trial – The Pediatric Infectious Disease Journal

Related:

Short- vs Standard-Course Outpatient Antibiotic Therapy for Community-Acquired Pneumonia in Children: The SCOUT-CAP Randomized Clinical Trial – JAMA Pediatrics

Appropriate Use of Short-Course Antibiotics in Common Infections: Best Practice Advice From the American College of Physicians – Annals of Internal Medicine

Short-Course Antimicrobial Therapy for Pediatric Community-Acquired Pneumonia: The SAFER Randomized Clinical Trial – JAMA Pediatrics

Effect of Amoxicillin Dose and Treatment Duration on the Need for Antibiotic Re-treatment in Children With Community-Acquired Pneumonia: The CAP-IT Randomized Clinical Trial – JAMA

Treatment of UTIs in Infants <2 Months: A Living Systematic Review – Hospital Pediatrics

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical Trial – JAMA

Seven versus fourteen Days of Antibiotic Therapy for uncomplicated Gram-negative Bacteremia: a Non-inferiority Randomized Controlled Trial – Clinical Infectious Diseases

Efficacy of short-course antibiotic treatments for community-acquired pneumonia in adults: A systematic review and meta-analysis – Antimicrobial Agents and Chemotherapy

 

Commentary on Twitter

 

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them.

29 Apr, 2022 | 10:51h | UTC

Bring it on: Top five antimicrobial stewardship challenges in transplant infectious diseases and practical strategies to address them – Antimicrobial Stewardship & Healthcare Epidemiology

 

Commentary on Twitter

Under a http://creativecommons.org/licenses/by/4.0/ license

 

M-A: Risk factors for acquired Stenotrophomonas maltophilia pneumonia in intensive care unit.

28 Apr, 2022 | 08:01h | UTC

Risk Factors for Acquired Stenotrophomonas maltophilia Pneumonia in Intensive Care Unit: A Systematic Review and Meta-Analysis – Frontiers in Medicine

 

Review: Use of antimicrobials for bloodstream infections in the intensive care unit.

27 Apr, 2022 | 01:34h | UTC

Use of Antimicrobials for Bloodstream Infections in the Intensive Care Unit, a Clinically Oriented Review – Antibiotics

 

Consensus for the treatment of tinea pedis.

26 Apr, 2022 | 08:02h | UTC

Consensus for the Treatment of Tinea Pedis: A Systematic Review of Randomised Controlled Trials – Journal of Fungi

 

Studies highlight meningitis vaccine’s potential against gonorrhea.

20 Apr, 2022 | 10:06h | UTC

Commentary: Studies highlight meningitis vaccine’s potential against gonorrhea – CIDRAP

News Release: Threat of untreatable gonorrhoea could be tackled using an existing meningitis vaccine – The Lancet

Study 1: Effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhoea: a retrospective observational study – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Study 2: Effectiveness and impact of the 4CMenB vaccine against invasive serogroup B meningococcal disease and gonorrhoea in an infant, child, and adolescent programme: an observational cohort and case-control study – The Lancet Infectious Diseases (link to abstract – $ for full-text)

Study 3: Public health impact and cost-effectiveness of gonorrhoea vaccination: an integrated transmission-dynamic health-economic modelling analysis – The Lancet Infectious Diseases

 

Expert Guidance: Strategies to prevent central line-associated bloodstream infections in acute-care hospitals.

20 Apr, 2022 | 10:13h | UTC

Strategies to prevent central line-associated bloodstream infections in acute-care hospitals: 2022 Update – Infection Control & Hospital Epidemiology

 

Commentary on Twitter

Article under a http://creativecommons.org/licenses/by/4.0/ license

 

AAOS Guideline: Prevention of surgical site infections after major extremity trauma.

19 Apr, 2022 | 02:35h | UTC

Prevention of Surgical Site Infections After Major Extremity Trauma: Evidence-Based Clinical Practice Guideline – American Academy of Orthopaedic Surgeons

Evidence Review: Prevention of Surgical Site Infection After Extremity Trauma (2022)

 

RCT: A 12-months oral itraconazole regimen is superior to 6-months of treatment to prevent relapses of chronic pulmonary aspergillosis.

18 Apr, 2022 | 10:36h | UTC

Efficacy of 12-months oral itraconazole versus 6-months oral itraconazole to prevent relapses of chronic pulmonary aspergillosis: an open-label, randomised controlled trial in India – The Lancet Infectious Diseases (link to abstract – $ for full-text)

 

Diarrhea during critical illness: a multicenter cohort study.

18 Apr, 2022 | 10:20h | UTC

Diarrhea during critical illness: a multicenter cohort study – Intensive Care Medicine

 

Commentary on Twitter

 

Guidelines for therapeutic drug monitoring of vancomycin in the framework of model-informed precision dosing.

18 Apr, 2022 | 10:26h | UTC

Clinical Practice Guidelines for Therapeutic Drug Monitoring of Vancomycin in the Framework of Model-Informed Precision Dosing: A Consensus Review by the Japanese Society of Chemotherapy and the Japanese Society of Therapeutic Drug Monitoring – Pharmaceutics

Related Guideline:

Guideline: Therapeutic monitoring of vancomycin for serious methicillin-resistant Staphylococcus aureus infections: A revised consensus guideline and review by the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists

Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review by the American Society of Health-system Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists – Clinical Infectious Diseases

 

Commentary on Twitter

 

Prospective validation of a rapid host gene expression test to discriminate bacterial from viral respiratory infection.

18 Apr, 2022 | 09:58h | UTC

Prospective Validation of a Rapid Host Gene Expression Test to Discriminate Bacterial From Viral Respiratory Infection – JAMA Network Open

 

Commentary on Twitter

 

Risk for asymptomatic household transmission of Clostridioides difficile infection associated with recently hospitalized family members.

18 Apr, 2022 | 09:41h | UTC

Risk for Asymptomatic Household Transmission of Clostridioides difficile Infection Associated with Recently Hospitalized Family Members – Emerging Infectious Diseases

Commentary: Recently Discharged Patients Pose Risk for Spreading C. Difficile Infection – HealthDay

 

Cluster RCT: A shorter antimicrobial prophylaxis duration (less than 24 hours after surgery) is noninferior to a more extended regimen (24-48 hours) after clean orthopedic surgery.

13 Apr, 2022 | 10:56h | UTC

Effect of Antimicrobial Prophylaxis Duration on Health Care–Associated Infections After Clean Orthopedic Surgery: A Cluster Randomized Trial – JAMA Network Open

 

Commentary on Twitter

 

Cluster RCT: A multifaceted intervention did not reduce catheter related bloodstream infections in patients on hemodialysis.

13 Apr, 2022 | 10:29h | UTC

Multifaceted intervention to reduce haemodialysis catheter related bloodstream infections: REDUCCTION stepped wedge, cluster randomised trial – The BMJ

 

Brief review | Infective endocarditis: words of caution for management.

13 Apr, 2022 | 10:12h | UTC

Infective Endocarditis: Words of Caution For Management – American College of Cardiology

Related:

Randomized Trial: Partial Oral vs. Intravenous Antibiotic Treatment of Endocarditis

Cohort Study: Socio-economic variations determine the clinical presentation, etiology and outcome of infective endocarditis.

Podcast: Infective Endocarditis Pearls.

AHA Statement: Prevention of Viridans Group Streptococcal Infective Endocarditis – Antibiotic prophylaxis for invasive dental procedures is suggested only for high-risk patients with the following conditions: 1) cardiac prosthetic valve; 2) previous infective endocarditis; 3) congenital heart disease; or 4) previous heart transplant

New-Generation Antibiotics for Treatment of Gram-Positive Infections: A Review with Focus on Endocarditis and Osteomyelitis

Review: Infective endocarditis after surgical and transcatheter aortic valve replacement

Infective Endocarditis: A Contemporary Review

Summary: Current AATS Guidelines on Surgical Treatment of Infective Endocarditis

Review: Current Evidence on Oral Antibiotics for Infective Endocarditis

[Abstract Only] Prevalence of Infective Endocarditis in Patients with Positive Blood Cultures According to the Organism

Observational Study Suggests Early Surgery is Associated with Reduced Mortality in Patients with Infective Endocarditis and Large Vegetation

Research: Invasive Procedures Associated With the Development of Infective Endocarditis

Meta-Analysis: Association of Vegetation Size With Embolic Risk in Patients With Infective Endocarditis

Prosthetic Valve Endocarditis After Surgical Aortic Valve Replacement

 

Empyema: ED presentation, evaluation, and management.

12 Apr, 2022 | 08:44h | UTC

Empyema: ED Presentation, Evaluation, and Management – emDocs

 

RCT: Effect of Gram Stain–Guided initial antibiotic therapy on clinical response in patients with ventilator-associated pneumonia.

11 Apr, 2022 | 01:36h | UTC

Effect of Gram Stain–Guided Initial Antibiotic Therapy on Clinical Response in Patients With Ventilator-Associated Pneumonia: The GRACE-VAP Randomized Clinical Trial – JAMA Network Open

Commentary: Can Gram Stains Guide Antibiotics for Pneumonia in Critical Care? – Medscape (free registration required)

 

Commentary on Twitter

 

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance hemodialysis.

8 Apr, 2022 | 10:18h | UTC

Interventions for treating catheter‐related bloodstream infections in people receiving maintenance haemodialysis – Cochrane Library

Summary: Interventions for treating catheter-related bloodstream infections in people receiving maintenance haemodialysis – Cochrane Library

 

RCT: Among patients with complicated urinary tract infection, oral Tebipenem Pivoxil Hydrobromide was noninferior to intravenous Ertapenem and showed a similar safety profile.

7 Apr, 2022 | 09:53h | UTC

Oral Tebipenem Pivoxil Hydrobromide in Complicated Urinary Tract Infection – New England Journal of Medicine (link to abstract – $ for full-text)

 

Commentary on Twitter

 

WHO Strategic framework for collaboration on antimicrobial resistance.

7 Apr, 2022 | 08:41h | UTC

Strategic framework for collaboration on antimicrobial resistance – World Health Organization

Related:

Four priority actions to slow the silent pandemic of antimicrobial resistance.

Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis.

Perspective | The hidden epidemic: Antibiotic resistance is approaching a crisis point, and the world needs to act.

 

Commentary on Twitter

 

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