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Hematology (all articles)

Research: Topical Tranexamic Acid Compared With Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs

26 Dec, 2017 | 23:12h | UTC

Topical Tranexamic Acid Compared With Anterior Nasal Packing for Treatment of Epistaxis in Patients Taking Antiplatelet Drugs: Randomized Controlled Trial – Academic Emergency Medicine (link to abstract – $ for full-text)

Commentary: Topical TXA in Epistaxis – R.E.B.E.L.em (free)

 


CAR T-Cell Therapies Drive Outcomes in Lymphoma, Myeloma

26 Dec, 2017 | 23:13h | UTC

CAR T-Cell Therapies Drive Outcomes in Lymphoma, Myeloma: Treatments Hold Promise for People with Hard-to-Treat Blood Cancers – 2017 American Society of Hematology Annual Meeting (free)

Related commentary: CAR T-Cell Therapy Makes Further Inroads in Lymphoma and Myeloma – ASCO Post (free)

Related Study: Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas – New England Journal of Medicine (free), Editorial: A Milestone for CAR T Cells (free) AND Visual Abstract (free)

 


Guideline: Myeloid Growth Factors

26 Dec, 2017 | 19:49h | UTC

Myeloid Growth Factors, Version 2.2017, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network (free)

 


Report: Traumatic Coagulopathy and Massive Transfusion

26 Dec, 2017 | 19:33h | UTC

Traumatic coagulopathy and massive transfusion: improving outcomes and saving blood – NIHR Journals Library (free)

 


Research: Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis

12 Dec, 2017 | 12:16h | UTC

Pharmacomechanical Catheter-Directed Thrombolysis for Deep-Vein Thrombosis – New England Journal of Medicine (free)

Commentaries: Pharmacomechanical Thrombolysis for Deep-Vein Thrombosis – NEJM Resident 360 (free) AND Pharmacomechanical Thrombolysis for DVT – American College of Cardiology, Latest in Cardiology (free)

Pharmacomechanical thrombolysis did not result in lower risk of post-thrombotic syndrome and was associated with higher risk of major bleeding.

 


Consensus on the Management of Bleeding in Patients on Oral Anticoagulants

5 Dec, 2017 | 18:35h | UTC

2017 ACC Expert Consensus Decision Pathway on Management of Bleeding in Patients on Oral Anticoagulants – Journal of The American College of Cardiology (free)

Commentary and Summary: Consensus for Management of Bleeding on Oral Anticoagulants – American College of Cardiology, Latest in Cardiology (free)

 


Guidelines for the use of imaging in the management of patients with myeloma

3 Dec, 2017 | 18:54h | UTC

Guidelines for the use of imaging in the management of patients with myeloma – British Journal of Haematology (free)

 


Guideline: Diagnosis and Management of Waldenström Macroglobulinemia

3 Dec, 2017 | 18:52h | UTC

Diagnosis and Management of Waldenström Macroglobulinemia: Mayo Stratification of Macroglobulinemia and Risk-Adapted Therapy (mSMART) Guidelines 2016 – JAMA Oncology (free)

Related review: Waldenström macroglobulinemia: 2017 update on diagnosis, risk stratification, and management – American Journal of Hematology (free)

 


Review: Head and Neck Lymphomas in HIV Patients

3 Dec, 2017 | 17:19h | UTC

Head and Neck Lymphomas in HIV Patients: a Clinical Perspective – International Archives of Otorhinolaryngology (free)

 


Review – Antithrombotics in trauma: management strategies in the older patients

3 Dec, 2017 | 17:12h | UTC

Antithrombotics in trauma: management strategies in the older patients – Journal of Blood Medicine (free)

 


Guideline: Platelet Transfusion for Patients With Cancer

30 Nov, 2017 | 18:14h | UTC

Platelet Transfusion for Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update (free)

 


Research: Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery

20 Nov, 2017 | 14:17h | UTC

Restrictive or Liberal Red-Cell Transfusion for Cardiac Surgery – New England Journal of Medicine (free)

Commentaries: TRICS III: Restrictive Red-Cell Transfusion Noninferior to Liberal Use in Cardiac Surgery – TCTMD (free) AHA: Restrictive Blood Transfusion OK for Select Patients – MedPage Today (free registration required)

Related article: Transfusion Requirements After Cardiac Surgery: The TRACS Randomized Controlled Trial – JAMA (free)

 


Review: Management of anticoagulation in hip fractures

14 Nov, 2017 | 20:36h | UTC

Management of anticoagulation in hip fractures – Effort Open Reviews (free)

 


Review: Role of liver magnetic resonance imaging in hyperferritinaemia and the diagnosis of iron overload

14 Nov, 2017 | 20:27h | UTC

Role of liver magnetic resonance imaging in hyperferritinaemia and the diagnosis of iron overload – Swiss Medical Weekly (free)

 


Guideline: Hairy Cell Leukemia

14 Nov, 2017 | 20:20h | UTC

Hairy Cell Leukemia, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology (free)

 


European guidelines on perioperative venous thromboembolism prophylaxis

11 Nov, 2017 | 19:14h | UTC

European guidelines on perioperative venous thromboembolism prophylaxis (free PDF articles):

– Editorial

– Executive Summary

– Intensive care

– Mechanical prophylaxis

– Patients with preexisting coagulation disorders and after severe perioperative bleeding

– Inferior vena cava filters

– Cardiovascular and thoracic surgery

– Neurosurgery

– Surgery in the elderly

– Surgery in the obese patient

– Surgery during pregnancy and the immediate postpartum period

– Day surgery and fast-track surgery

– Chronic treatments with antiplatelet agents

– Aspirin

 


Meta-analysis – Tranexamic acid: is it about time?

11 Nov, 2017 | 17:14h | UTC

Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients – The Lancet (free)

Commentaries: Tranexamic acid: is it about time? – The Lancet (free) Rapid use of blood drug could save thousands of lives, study finds – The Guardian (free) AND Severely bleeding patients must receive lifesaving drug within minutes, not hours – London School of Hygiene & Tropical Medicine, via EurekAlert (free)

 


Research: Association of Warfarin Use With Lower Overall Cancer Incidence

11 Nov, 2017 | 16:56h | UTC

Association of Warfarin Use With Lower Overall Cancer Incidence Among Patients Older Than 50 Years – JAMA Internal Medicine (free)

“In this population-based cohort study of 1.256.725 persons, there was a significantly lower age- and sex-adjusted incidence rate ratio of cancer among warfarin users vs nonusers”.

 


Policy Statement: Cord Blood Banking for Potential Future Transplantation

5 Nov, 2017 | 19:34h | UTC

Cord Blood Banking for Potential Future Transplantation – American Academy of Pediatrics (free)

News release: Updated policy reaffirms value of public over private cord blood banks (free)

Commentaries: Pediatrics Group Updates Recommendations on Cord Blood Banking – Physician’s First Watch (free)

 


Systematic review: antibiotics for preventing pneumococcal infection in children with sickle cell disease

29 Oct, 2017 | 01:37h | UTC

Regular antibiotics for preventing pneumococcal infection in young children with sickle cell disease – Cochrane Library (free)

Original article: Prophylactic antibiotics for preventing pneumococcal infection in children with sickle cell disease – Cochrane Library (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


Research: Pregnancy, thrombophilia, and the risk of a first venous thrombosis

29 Oct, 2017 | 01:36h | UTC

Pregnancy, thrombophilia, and the risk of a first venous thrombosis: systematic review and bayesian meta-analysis – The BMJ (free)

“Women with antithrombin, protein C, or protein S deficiency or with homozygous factor V Leiden should be considered for antepartum or postpartum thrombosis prophylaxis, or both”.

 


Review: Thrombophilia Testing and Venous Thrombosis

23 Oct, 2017 | 20:46h | UTC

Summary with 10 key points to remember: Thrombophilia Testing and Venous Thrombosis – American College of Cardiology, Latest in Cardiology (free)

See also: Thrombophilia Testing and Venous Thrombosis – NEJM Resident 360 (free)

Original article: Thrombophilia Testing and Venous Thrombosis – New England Journal of Medicine (link to abstract – $ for full-text)

 


Research: Receipt of Blood Transfusion From Previously Pregnant Donor Associated with Increased Risk of Death Among Male Recipients

21 Oct, 2017 | 17:33h | UTC

Association of Blood Transfusion From Female Donors With and Without a History of Pregnancy With Mortality Among Male and Female Transfusion Recipients – JAMA (link to abstract – $ for full-text)

Commentaries: Blood Boundaries: Should Transfusions Be Matched by Sex? – Scientific American (free) AND Are transfusions harmful to men if the blood comes from women who have been pregnant? – STAT (free) AND Receipt of Blood Transfusion From Previously Pregnant Donor Associated with Increased Risk of Death Among Male Recipients – The JAMA Network (free)

 


Research: Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism

21 Oct, 2017 | 17:30h | UTC

Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism: multicentre, population based, observational study – The BMJ (free)

Commentary: New Anticoagulants Not Linked To Excess Bleeding Rates – Cardiobrief (free)

 


Research: Iron absorption from oral iron supplements given on consecutive versus alternate days

17 Oct, 2017 | 19:10h | UTC

Iron absorption from oral iron supplements given on consecutive versus alternate days and as single morning doses versus twice-daily split dosing in iron-depleted women: two open-label, randomised controlled trials – The Lancet Haematology (free)

Commentaries: Treatment of iron deficiency is getting trendy – The Lancet Haematology (free) AND Taking Iron Every Other Day Linked to Better Absorption in Iron-Deficient Women – Physician’s First Watch (free)

 


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