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Hematology (all articles)

Cohort Study: Common Conditions Associated with Hereditary Hemochromatosis Genetic Variants

18 Jan, 2019 | 01:03h | UTC

Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank – The BMJ (free)

Commentaries: Haemochromatosis: disorder that causes body to absorb too much iron from food may be major cause of disease – The Conversation (free) AND Haemochromatosis is linked to more disease than previously thought – The BMJ Opinion (free) AND Health impact of genetic ‘iron-overdose disease’ may have been underestimated – NHS News (free)

 


Randomized Trial: Hematopoietic Stem Cell Transplantation for Patients with Multiple Sclerosis

16 Jan, 2019 | 00:51h | UTC

Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

See also: Visual Abstract (free)

Commentaries: For some multiple sclerosis patients, knocking out the immune system might work better than drugs – Science (free) AND A remarkable new study shows stem cells can reverse MS in some patients – Vox (free) AND Expert reaction to study looking at blood stem cell transplantation as a MS treatment – Science Media Centre (free)

 


Perioperative Thrombocytopenia: Evidence, Evaluation, and Emerging Therapies

15 Jan, 2019 | 00:19h | UTC

Perioperative thrombocytopenia: evidence, evaluation, and emerging therapies – British Journal of Anaesthesia (free)

 


Review: Management of Acquired Hemophilia A

13 Jan, 2019 | 17:14h | UTC

Management of acquired hemophilia A: Review of current evidence – Transfusion and Apheresis Science (free)

 


Systematic Review: Treatment of Localized Extranodal NK/T Cell Lymphoma, Nasal Type

13 Jan, 2019 | 16:56h | UTC

Treatment of localized extranodal NK/T cell lymphoma, nasal type: a systematic review – Journal of Hematology and Oncology (free)

 


Review: Primary Central Nervous System Lymphoma

13 Jan, 2019 | 16:27h | UTC

Primary Central Nervous System Lymphoma: Molecular Pathogenesis and Advances in Treatment – Translational Oncology (free)

 


Monoclonal Gammopathy of Undetermined Significance: A Primary Care Guide

10 Jan, 2019 | 21:03h | UTC

Monoclonal gammopathy of undetermined significance: A primary care guide – Cleveland Clinic Journal of Medicine (free)

 


NCCN Guideline: Systemic Mastocytosis

9 Jan, 2019 | 08:48h | UTC

Systemic Mastocytosis, Version 2.2019, NCCN Clinical Practice Guidelines in Oncology – Journal of the National Comprehensive Cancer Network (free)

 


Randomized Trial: Treatments for Newly Diagnosed Multiple Myeloma Compared

8 Jan, 2019 | 09:22h | UTC

Lenalidomide maintenance versus observation for patients with newly diagnosed multiple myeloma (Myeloma XI): a multicentre, open-label, randomised, phase 3 trial – The Lancet Oncology (free)

Invited Commentary: Lenalidomide as maintenance for every newly diagnosed patient with multiple myeloma (free)

 


Review: Chimeric Antigen Receptor (CAR) T Therapies for the Treatment of Hematologic Malignancies

6 Jan, 2019 | 20:51h | UTC

Chimeric antigen receptor (CAR) T therapies for the treatment of hematologic malignancies: clinical perspective and significance – Journal for ImmunoTherapy of Cancer (free)

 


Study: Risk of Solid Subsequent Malignant Neoplasms after Childhood Hodgkin Lymphoma

4 Jan, 2019 | 20:30h | UTC

Risk of solid subsequent malignant neoplasms after childhood Hodgkin lymphoma–identification of high‐risk populations to guide surveillance: A report from the Late Effects Study Group – Cancer (free)

Commentary: High Long-Term Risk of Solid Cancers in Survivors of Childhood Hodgkin Lymphoma – The ASCO Post (free)

 


Study: CAR-T cell Therapy Evaluated for Refractory Diffuse Large B-Cell Lymphoma

4 Jan, 2019 | 20:28h | UTC

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: CAR-T cell update: Therapy improves outcomes for patients with B-cell lymphoma – University of Chicago Medical Center (free)

 


Systematic Review: Transfusion of Red Blood Cells Stored for Shorter vs. Longer Duration

4 Jan, 2019 | 20:06h | UTC

Transfusion of red blood cells stored for shorter versus longer duration for all conditions – Cochrane Library (free)

Summary: Transfusion of red blood cells stored for a shorter duration versus red blood cells stored for a longer duration for all conditions – Cochrane Library (free)

 

 


Guideline: Management of Primary Cutaneous Lymphomas

3 Jan, 2019 | 11:52h | UTC

British Association of Dermatologists and U.K. Cutaneous Lymphoma Group guidelines for the management of primary cutaneous lymphomas 2018 – British Journal of Dermatology (free)

 


Italian Recommendations for Placental Transfusion Strategies

3 Jan, 2019 | 11:50h | UTC

Italian Recommendations for Placental Transfusion Strategies – Frontiers in Pediatrics (free)

 


Study: Chemotherapy for Solid Tumors Associated with Development of Therapy-Related Myelodysplastic Syndrome or Acute Myeloid Leukemia

3 Jan, 2019 | 11:25h | UTC

Association of Chemotherapy for Solid Tumors With Development of Therapy-Related Myelodysplastic Syndrome or Acute Myeloid Leukemia in the Modern Era – JAMA Oncology (link to abstract – $ for full-text)

Commentary: Study finds elevated risk of certain rare blood cancers after chemotherapy for most solid tumors – NIH News Releases (free)

 


Meta-Analysis: The Global Burden of Sickle Cell Disease in Children Under Five Years of Age

3 Jan, 2019 | 11:14h | UTC

The global burden of sickle cell disease in children under five years of age: a systematic review and meta-analysis – Journal of Global Health (free)

 


Review: Antiphospholipid Syndrome and the Neurologist

13 Dec, 2018 | 18:44h | UTC

Antiphospholipid Syndrome and the Neurologist: From Pathogenesis to Therapy – Frontiers in Neurology (free)

 


ASCO Guideline Endorsement Summary: Initial Diagnostic Workup of Acute Leukemia

13 Dec, 2018 | 18:09h | UTC

Initial Diagnostic Workup of Acute Leukemia: ASCO Clinical Practice Guideline Endorsement Summary of the CAP and ASH Guideline – Journal of Oncology Practice (free)

 


Consensus Report: Evaluation of Monoclonal Gammopathy of Renal Significance

13 Dec, 2018 | 18:04h | UTC

The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group – Nature Reviews Nephrology (free)

 


tudy: Axicabtagene Ciloleucel in Refractory Large B-cell Lymphoma

3 Dec, 2018 | 23:41h | UTC

Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1–2 trial – The Lancet Oncology (free)

Commentary: ASH 2018: More than half of patients alive two years after receiving CAR-T therapy for diffuse large B-cell lymphoma in ZUMA-1 trial – eCancer News (free)

 


Study: Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma

3 Dec, 2018 | 23:40h | UTC

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma – New England Journal of Medicine (free)

See also: ASH 2018: Updated Analysis of JULIET Trial: Tisagenlecleucel in Relapsed or Refractory DLBCL – The ASCO Post (free)

 


Randomized Trial: Ibrutinib Regimens vs. Chemoimmunotherapy in Older Patients with Untreated CLL

3 Dec, 2018 | 23:39h | UTC

Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL – New England Journal of Medicine (free)

Commentary: ASH 2018: Ibrutinib Alone or in Combination With Rituximab vs Bendamustine Plus Rituximab in Older Patients With CLL – The ASCO Post (free)

 


Study: Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa

2 Dec, 2018 | 23:28h | UTC

Hydroxyurea for Children with Sickle Cell Anemia in Sub-Saharan Africa – New England Journal of Medicine (free)

Commentaries: Studies Show Improved Sickle Cell Disease Outcomes Worldwide – American Society of Hematology (free) AND ASH 2018: Large Single-Arm Trial of Hydroxyurea for Sickle Cell Anemia in Sub-Saharan Africa – The ASCO Post (free) AND Sickle cell anemia treatment safely lowers disease burden in African children – Cincinnati Children’s Hospital Medical Center (free) AND ‘From Nothing to Gangbusters’: A Treatment for Sickle-Cell Disease Proves Effective in Africa – New England Journal of Medicine (10 articles per month are free)

 


Guideline: Diagnosis and Management of Polycythaemia Vera

30 Nov, 2018 | 02:51h | UTC

A guideline for the diagnosis and management of polycythaemia vera. A British Society for Haematology Guideline (free)

 


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