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Hematology (all articles)

Meta-Analysis: Vitamin K for Reversal of Excessive Vitamin K Antagonist Anticoagulation

21 Mar, 2019 | 07:09h | UTC

Vitamin K for reversal of excessive vitamin K antagonist anticoagulation: a systematic review and meta-analysis – Blood Advances (free)

Our findings indicate that patients on VKA therapy who have an INR between 4.5 and 10.0 without bleeding are not likely to benefit from vitamin K administration in addition to temporary VKA cessation.”

 


Diagnostic Test Interpretation: Evaluating the Erythrocyte Sedimentation Rate

20 Mar, 2019 | 03:25h | UTC

Evaluating the Erythrocyte Sedimentation Rate – JAMA (free for a limited period)

 


Patient Blood Management Recommendations From the 2018 Frankfurt Consensus Conference

17 Mar, 2019 | 18:57h | UTC

Patient Blood Management Recommendations From the 2018 Frankfurt Consensus Conference – JAMA (free for a limited period)

 


Consensus Statement: Prevention and Treatment of Postpartum Hemorrhage

15 Mar, 2019 | 02:59h | UTC

Patient blood management in obstetrics: prevention and treatment of postpartum haemorrhage. A NATA consensus statement – Blood Transfusion (free)

 


Consensus Statement: Management of Adult Patients with Traumatic Brain Injury Receiving Oral Anticoagulant Therapy

12 Mar, 2019 | 13:01h | UTC

Diagnostic and therapeutic approach in adult patients with traumatic brain injury receiving oral anticoagulant therapy: an Austrian interdisciplinary consensus statement – Critical Care (free)

 


Three Neglected Numbers in the CBC: The RDW, MPV, and NRBC count

12 Mar, 2019 | 02:43h | UTC

Review: Three neglected numbers in the CBC: The RDW, MPV, and NRBC count – Cleveland Clinic Journal of Medicine (free)

 


Second Patient Free of HIV After Stem-cell Therapy

6 Mar, 2019 | 01:29h | UTC

Second patient free of HIV after stem-cell therapy – Nature News (free)

See also: Has a second person with HIV been cured? – Science (free) AND Expert reaction to HIV-1 remission in a second patient – Science Media Centre (free) AND Bone Marrow Transplant Renders Second Patient Free Of HIV – NPR (free) AND London patient might be second to be cured of HIV – CNN (free) AND H.I.V. Is Reported Cured in a Second Patient, a Milestone in the Global AIDS Epidemic – The New York Times (10 articles per month are free)

 


Review: Prevention and Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis

27 Feb, 2019 | 13:08h | UTC

Prevention and Treatment of Chemotherapy and Radiotherapy Induced Oral Mucositis – Medicina (free)

 


Guideline: Management of Sepsis in Neutropenic Cancer Patients

26 Feb, 2019 | 02:32h | UTC

Management of sepsis in neutropenic cancer patients: 2018 guidelines from the Infectious Diseases Working Party (AGIHO) and Intensive Care Working Party (iCHOP) of the German Society of Hematology and Medical Oncology (DGHO) – Annals of Hematology (free)

Related Guidelines: SEOM clinical practice guideline: management and prevention of febrile neutropenia in adults with solid tumors (2018) – Clinical and Translational Oncology (free) AND Outpatient Management of Fever and Neutropenia in Adults Treated for Malignancy: American Society of Clinical Oncology and Infectious Diseases Society of America Clinical Practice Guideline Update – Journal of Clinical Oncology (free) AND Diagnosis and empirical treatment of fever of unknown origin (FUO) in adult neutropenic patients: guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO) (free) AND Management of febrile neutropaenia: ESMO Clinical Practice Guidelines (free) AND Guideline for the Management of Fever and Neutropenia in Children With Cancer and Hematopoietic Stem-Cell Transplantation Recipients: 2017 Update (free)

 


IgG4-Related Disease: What A Hematologist Needs to Know

25 Feb, 2019 | 00:35h | UTC

IgG4-Related Disease: What A Hematologist Needs To Know – Haematologica (free PDF)

 


Australian Guideline for the Diagnosis and Management of Venous Thromboembolism

12 Feb, 2019 | 00:31h | UTC

New guidelines from the Thrombosis and Haemostasis Society of Australia and New Zealand for the diagnosis and management of venous thromboembolism – The Medical Journal of Australia (free for 7 days)

News Release: New Guidelines for Venous Thromboembolism (free)

Related Guidelines: BTS Guideline: Outpatient Management of Pulmonary Embolism (free) AND ACEP Clinical Policy: Evaluation and Management of Suspected Acute Venous Thromboembolism (free) AND Evaluation of Patients With Suspected Acute Pulmonary Embolism: Best Practice Advice From the Clinical Guidelines Committee of the American College of Physicians (free) AND 2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC) (free)

 

Related Commentary on Twitter

 


2019 NCCN Consensus Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma

11 Feb, 2019 | 21:05h | UTC

2019 NCCN Consensus Guidelines on the Diagnosis and Treatment of Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) – Aesthetic Surgery Journal (free)

Related: FDA Report: 660 Cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma (free report and commentaries)

 


Consensus: Assessment and Management of Measurable Residual Disease in Adults with Acute Lymphoblastic Leukemia

3 Feb, 2019 | 16:44h | UTC

Recommendations for the assessment and management of measurable residual disease in adults with acute lymphoblastic leukemia: A consensus of North American experts – American Journal of Hematology (free)

 


Treatment Guidelines for Idiopathic Multicentric Castleman Disease

27 Jan, 2019 | 19:05h | UTC

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease – Blood (free)

 


NCCN Guideline: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

27 Jan, 2019 | 18:48h | UTC

NCCN Guidelines Insights: Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma, Version 2.2019 – Journal of the National Comprehensive Cancer Network (free)

 


Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report

27 Jan, 2019 | 18:47h | UTC

Revised Adult T-Cell Leukemia-Lymphoma International Consensus Meeting Report – Journal of Clinical Oncology (free)

 


BSH Guideline for the Management of Specific Situations in Polycythemia Vera and Secondary Erythrocytosis

24 Jan, 2019 | 18:11h | UTC

A guideline for the management of specific situations in polycythaemia vera and secondary erythrocytosis: A British Society for Haematology Guideline – British Journal of Haematology (free)

Related Guideline: A guideline for the diagnosis and management of polycythaemia vera. A British Society for Haematology Guideline (free)

 


Systematic Review: Early Discontinuation of Antibiotics for Febrile Neutropenia vs. Continuation Until Neutropenia Resolution in People with Cancer

24 Jan, 2019 | 00:17h | UTC

Early discontinuation of antibiotics for febrile neutropenia versus continuation until neutropenia resolution in people with cancer – Cochrane Library (free)

Summary: Stopping antibiotic therapy early versus continuing until normal neutrophil count in people with cancer with fever and low neutrophil counts – Cochrane Library (free)

 


Initial Diagnostic Work-Up of Acute Leukemia: ASCO Clinical Practice Guideline Endorsement

23 Jan, 2019 | 15:31h | UTC

Initial Diagnostic Work-Up of Acute Leukemia: ASCO Clinical Practice Guideline Endorsement of the College of American Pathologists and American Society of Hematology Guideline – Journal of Clinical Oncology (free)

 


Podcast: Sickle Cell Disease, Management & Complications

22 Jan, 2019 | 00:11h | UTC

#136 Sickle Cell Disease, Management & Complications – The Curbsiders Internal Medicine Podcast (free)

 


New Treatment for Acquired Thrombotic Thrombocytopenic Purpura

21 Jan, 2019 | 10:12h | UTC

Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: A New Drug for Patients with Thrombotic Thrombocytopenic Purpura – Transfusion News (free)

 


Randomized Trial: Ibrutinib Regimens vs.Chemoimmunotherapy in Older Patients with Untreated CLL

20 Jan, 2019 | 13:40h | UTC

Ibrutinib Regimens versus Chemoimmunotherapy in Older Patients with Untreated CLL – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Ibrutinib vs Standard of Care in Front-Line Treatment of Older Patients With Chronic Lymphocytic Leukemia – The ASCO Post (free) AND Ibrutinib Regimens Have Superior PFS Compared With Chemoimmunotherapy in Older Patients With Untreated CLL – AJMC (free)

 


Cohort Study: Common Conditions Associated with Hereditary Hemochromatosis Genetic Variants

18 Jan, 2019 | 01:03h | UTC

Common conditions associated with hereditary haemochromatosis genetic variants: cohort study in UK Biobank – The BMJ (free)

Commentaries: Haemochromatosis: disorder that causes body to absorb too much iron from food may be major cause of disease – The Conversation (free) AND Haemochromatosis is linked to more disease than previously thought – The BMJ Opinion (free) AND Health impact of genetic ‘iron-overdose disease’ may have been underestimated – NHS News (free)

 


Randomized Trial: Hematopoietic Stem Cell Transplantation for Patients with Multiple Sclerosis

16 Jan, 2019 | 00:51h | UTC

Effect of Nonmyeloablative Hematopoietic Stem Cell Transplantation vs Continued Disease-Modifying Therapy on Disease Progression in Patients With Relapsing-Remitting Multiple Sclerosis: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

See also: Visual Abstract (free)

Commentaries: For some multiple sclerosis patients, knocking out the immune system might work better than drugs – Science (free) AND A remarkable new study shows stem cells can reverse MS in some patients – Vox (free) AND Expert reaction to study looking at blood stem cell transplantation as a MS treatment – Science Media Centre (free)

 


Perioperative Thrombocytopenia: Evidence, Evaluation, and Emerging Therapies

15 Jan, 2019 | 00:19h | UTC

Perioperative thrombocytopenia: evidence, evaluation, and emerging therapies – British Journal of Anaesthesia (free)

 


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