Hematology (all articles)
[Abstract Only] Randomized Trial: Luspatercept in Patients with Lower-Risk Myelodysplastic Syndromes
14 Jan, 2020 | 00:03h | UTCLuspatercept in Patients with Lower-Risk Myelodysplastic Syndromes – New England Journal of Medicine (link to abstract – $ for full-text)
Systematic Review and Economic Evaluation: Different Strategies for Pharmacological Thromboprophylaxis for Lower-limb Immobilization after Injury
12 Jan, 2020 | 21:14h | UTCSource: EvidenceAlerts
New Guideline on the Management of Epistaxis
10 Jan, 2020 | 08:30h | UTCClinical Practice Guideline: Nosebleed (Epistaxis) – Otolaryngology–Head and Neck Surgery (free)
Executive Summary: Clinical Practice Guideline: Nosebleed (Epistaxis) – Otolaryngology–Head and Neck Surgery (free)
News Release: Nosebleed (epistaxis): New clinical practice guideline – American Academy of Otolaryngology-Head and Neck Surgery (free)
Study Commentary: Herpes Zoster Vaccine Reduces Chances of Shingles after Stem Cell Transplants
9 Jan, 2020 | 23:22h | UTCHerpes zoster vaccine reduces chances of shingles after stem cell transplants – NIHR Signal (free)
Original Study: Effect of Recombinant Zoster Vaccine on Incidence of Herpes Zoster After Autologous Stem Cell Transplantation: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Study Commentary: Continuing an Anticoagulant at Home After Abdominal Surgery Cuts Thrombosis Risk
9 Jan, 2020 | 23:21h | UTCContinuing an anticoagulant at home after abdominal surgery cuts thrombosis risk – NIHR Signal (free)
Original Study: Systematic Review: Prolonged Thromboprophylaxis with Low Molecular Weight Heparin for Abdominal or Pelvic Surgery – Cochrane Library (link to study and summary)
[Abstract Only] Randomized Trial: Four Cycles of R-CHOP Non-inferior to Six Cycles of R-CHOP in Patients with Aggressive B-cell non-Hodgkin Lymphoma and Favorable Prognosis
8 Jan, 2020 | 21:49h | UTCFour versus six cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): a randomised, phase 3, non-inferiority trial – The Lancet (link to abstract – $ for full-text)
Related Commentary on Twitter
Four cycles of CHOP chemotherapy in combination with six applications of rituximab in patients with aggressive B-cell lymphoma with favourable prognosis (FLYER): The new standard of care for limited DLBCL with favorable prognosis https://t.co/oAH9dJJGZA
— Georgios Pongas, MD (@pongasg) December 24, 2019
[Abstract Only] Randomized Trial: Overall Survival with Daratumumab, Bortezomib, Melphalan, and Prednisone in Newly Diagnosed Multiple Myeloma
8 Jan, 2020 | 21:47h | UTCOverall survival with daratumumab, bortezomib, melphalan, and prednisone in newly diagnosed multiple myeloma (ALCYONE): a randomised, open-label, phase 3 trial – The Lancet (link to abstract – $ for full-text)
Commentary: Overall Survival With the Addition of Daratumumab to VMP in Newly Diagnosed, Transplant-Ineligible Multiple Myeloma -The ASCO Post (free)
Guideline: Transfusion Strategies in Non-bleeding Critically Ill Adults
8 Jan, 2020 | 08:50h | UTCEditorial: Transfusion thresholds: the dangers of guidelines based on randomized controlled trials (free)
[Abstract Only] Randomized Trial: Direct Oral Anticoagulant Similarly Effective as Standard Anticoagulants for the Treatment of Acute Venous Thromboembolism in Children
8 Jan, 2020 | 01:02h | UTCRivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)
Commentary: Thrombosis: Anticoagulant Rivaroxaban soon also available for children – Medical University of Vienna (free)
[Abstract Only] Study: Long-term Follow Up of Gene Therapy for Hemophilia A
8 Jan, 2020 | 00:52h | UTCMultiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Study shows safety, long-term beneficial impact of gene therapy for patients with Hemophilia A – Queen Mary University of London (free)
Consensus: Diagnosis and Treatment of Autoimmune Hemolytic Anemia in Adults
7 Jan, 2020 | 01:41h | UTCRelated: Autoimmune hemolytic anemia – Hematology (free) AND Guidelines on the management of drug‐induced immune and secondary autoimmune, haemolytic anaemia – British Journal of Haematology (free)
Position Statement: Diagnosis, Grading, and Treatment Recommendations for Children, Adolescents, and Young Adults with Sinusoidal Obstructive Syndrome
6 Jan, 2020 | 23:03h | UTCDiagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement – The Lancet Haematology (free registration required)
Commentary: MD Anderson-convened consortium provides first universal recommendations for pediatric patients with sinusoidal obstructive syndrome (free)
Randomized Trial: Fresh Red Blood Cell Transfusions Not Better Than Standard-issue Red Blood Cell Transfusions in Critically Ill Pediatric Patients
13 Dec, 2019 | 10:20h | UTCEffect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Age of Red Blood Cells for Transfusion in Critically Ill Pediatric Patients (free for a limited period)
Commentaries: Fresh red blood cell transfusions do not help critically ill children more than older cells – NIH News Releases (free) AND Blood transfusions: Fresh red blood cells no better than older ones – University of Montreal (free)
Choosing Wisely in Pediatric Hematology: Five Things Physicians and Patients Should Question
11 Dec, 2019 | 08:16h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Source: NEJM Journal Watch
Editorial: Is Tranexamic Acid Going to CRASH the Management of Traumatic Brain Injury?
10 Dec, 2019 | 08:34h | UTCOriginal Study: Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial – The Lancet (free study and commentaries)
ASH Guideline: Prevention of Venous Thromboembolism in Surgical Hospitalized Patients
5 Dec, 2019 | 11:29h | UTCRelated: European guidelines on perioperative venous thromboembolism prophylaxis – European Journal of Anaesthesiology (comprehensive resource on the subject) AND American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Prophylaxis for Hospitalized and Nonhospitalized Medical Patients (free)
ASH Guideline: Cardiopulmonary and Kidney Disease in Sickle Cell Disease
5 Dec, 2019 | 11:25h | UTC
ASH Guideline: Immune Thrombocytopenia
5 Dec, 2019 | 11:19h | UTCAmerican Society of Hematology 2019 guidelines for immune thrombocytopenia – Blood Advances (free)
Related: Consensus Report: Investigation and Management of Primary Immune Thrombocytopenia (guidelines and reviews on the subject)
Bridging Anticoagulation Therapy: A Teachable Moment
29 Nov, 2019 | 07:37h | UTCBridging Anticoagulation Therapy: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
Related: 2017 ACC Expert Consensus Decision Pathway for Periprocedural Management of Anticoagulation in Patients With Nonvalvular Atrial Fibrillation (free) AND Bridging Anticoagulation: Primum Non Nocere – Journal of the American College of Cardiology (free) AND Periprocedural heparin bridging in patients receiving oral anticoagulation: a systematic review and meta-analysis – BMC Cardiovascular Disorders (free) AND Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation – New England Journal of Medicine (free)
Consensus Report: Investigation and Management of Primary Immune Thrombocytopenia
28 Nov, 2019 | 10:31h | UTCRelated: Immune Thrombocytopenia – Current Diagnostics and Therapy: Recommendations of a Joint Working Group of DGHO, ÖGHO, SGH, GPOH, and DGTI – Oncology Research and Treatment (free) AND Clinical updates in adult immune thrombocytopenia – Blood (free) AND Management of immune thrombocytopenia: Korean experts recommendation in 2017 – Blood Research (free)
Iron Deficiency Anemia Revisited
26 Nov, 2019 | 07:35h | UTCIron deficiency anaemia revisited – Journal of Internal Medicine (free)
Related: How we diagnose and treat iron deficiency anemia – American Journal of Hematology (free)
Consensus Recommendations: Management of Adults and Children Undergoing CAR T-Cell Therapy
24 Nov, 2019 | 20:42h | UTC
Meta-Analysis: Bleeding and Ischemic Outcomes in Patients Treated with Dual vs. Triple Antithrombotic Therapy
22 Nov, 2019 | 08:26h | UTC
Consensus Document: Management of Invasive Fungal Diseases in Pediatric Patients with Hematologic Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation
18 Nov, 2019 | 00:34h | UTC
Guideline for Antibacterial Prophylaxis Administration in Pediatric Cancer and Hematopoietic Stem Cell Transplantation
14 Nov, 2019 | 10:32h | UTC