Hematology (all articles)
[Abstract Only] Study: Long-term Follow Up of Gene Therapy for Hemophilia A
8 Jan, 2020 | 00:52h | UTCMultiyear Follow-up of AAV5-hFVIII-SQ Gene Therapy for Hemophilia A – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Study shows safety, long-term beneficial impact of gene therapy for patients with Hemophilia A – Queen Mary University of London (free)
Consensus: Diagnosis and Treatment of Autoimmune Hemolytic Anemia in Adults
7 Jan, 2020 | 01:41h | UTCRelated: Autoimmune hemolytic anemia – Hematology (free) AND Guidelines on the management of drug‐induced immune and secondary autoimmune, haemolytic anaemia – British Journal of Haematology (free)
Position Statement: Diagnosis, Grading, and Treatment Recommendations for Children, Adolescents, and Young Adults with Sinusoidal Obstructive Syndrome
6 Jan, 2020 | 23:03h | UTCDiagnosis, grading, and treatment recommendations for children, adolescents, and young adults with sinusoidal obstructive syndrome: an international expert position statement – The Lancet Haematology (free registration required)
Commentary: MD Anderson-convened consortium provides first universal recommendations for pediatric patients with sinusoidal obstructive syndrome (free)
Randomized Trial: Fresh Red Blood Cell Transfusions Not Better Than Standard-issue Red Blood Cell Transfusions in Critically Ill Pediatric Patients
13 Dec, 2019 | 10:20h | UTCEffect of Fresh vs Standard-issue Red Blood Cell Transfusions on Multiple Organ Dysfunction Syndrome in Critically Ill Pediatric Patients: A Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Age of Red Blood Cells for Transfusion in Critically Ill Pediatric Patients (free for a limited period)
Commentaries: Fresh red blood cell transfusions do not help critically ill children more than older cells – NIH News Releases (free) AND Blood transfusions: Fresh red blood cells no better than older ones – University of Montreal (free)
Choosing Wisely in Pediatric Hematology: Five Things Physicians and Patients Should Question
11 Dec, 2019 | 08:16h | UTCSee complete lists of low-value practices: Choosing Wisely U.S. / Choosing Wisely UK / Choosing Wisely Australia AND Choosing Wisely Canada
Source: NEJM Journal Watch
Editorial: Is Tranexamic Acid Going to CRASH the Management of Traumatic Brain Injury?
10 Dec, 2019 | 08:34h | UTCOriginal Study: Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial – The Lancet (free study and commentaries)
ASH Guideline: Prevention of Venous Thromboembolism in Surgical Hospitalized Patients
5 Dec, 2019 | 11:29h | UTCRelated: European guidelines on perioperative venous thromboembolism prophylaxis – European Journal of Anaesthesiology (comprehensive resource on the subject) AND American Society of Hematology 2018 Guidelines for Management of Venous Thromboembolism: Prophylaxis for Hospitalized and Nonhospitalized Medical Patients (free)
ASH Guideline: Cardiopulmonary and Kidney Disease in Sickle Cell Disease
5 Dec, 2019 | 11:25h | UTC
ASH Guideline: Immune Thrombocytopenia
5 Dec, 2019 | 11:19h | UTCAmerican Society of Hematology 2019 guidelines for immune thrombocytopenia – Blood Advances (free)
Related: Consensus Report: Investigation and Management of Primary Immune Thrombocytopenia (guidelines and reviews on the subject)
Bridging Anticoagulation Therapy: A Teachable Moment
29 Nov, 2019 | 07:37h | UTCBridging Anticoagulation Therapy: A Teachable Moment – JAMA Internal Medicine (free for a limited period)
Related: 2017 ACC Expert Consensus Decision Pathway for Periprocedural Management of Anticoagulation in Patients With Nonvalvular Atrial Fibrillation (free) AND Bridging Anticoagulation: Primum Non Nocere – Journal of the American College of Cardiology (free) AND Periprocedural heparin bridging in patients receiving oral anticoagulation: a systematic review and meta-analysis – BMC Cardiovascular Disorders (free) AND Perioperative Bridging Anticoagulation in Patients with Atrial Fibrillation – New England Journal of Medicine (free)
Consensus Report: Investigation and Management of Primary Immune Thrombocytopenia
28 Nov, 2019 | 10:31h | UTCRelated: Immune Thrombocytopenia – Current Diagnostics and Therapy: Recommendations of a Joint Working Group of DGHO, ÖGHO, SGH, GPOH, and DGTI – Oncology Research and Treatment (free) AND Clinical updates in adult immune thrombocytopenia – Blood (free) AND Management of immune thrombocytopenia: Korean experts recommendation in 2017 – Blood Research (free)
Iron Deficiency Anemia Revisited
26 Nov, 2019 | 07:35h | UTCIron deficiency anaemia revisited – Journal of Internal Medicine (free)
Related: How we diagnose and treat iron deficiency anemia – American Journal of Hematology (free)
Consensus Recommendations: Management of Adults and Children Undergoing CAR T-Cell Therapy
24 Nov, 2019 | 20:42h | UTC
Meta-Analysis: Bleeding and Ischemic Outcomes in Patients Treated with Dual vs. Triple Antithrombotic Therapy
22 Nov, 2019 | 08:26h | UTC
Consensus Document: Management of Invasive Fungal Diseases in Pediatric Patients with Hematologic Cancer and/or Undergoing Hematopoietic Stem Cell Transplantation
18 Nov, 2019 | 00:34h | UTC
Guideline for Antibacterial Prophylaxis Administration in Pediatric Cancer and Hematopoietic Stem Cell Transplantation
14 Nov, 2019 | 10:32h | UTC
Study: Testosterone Therapy Linked to Increased Risk of Venous Thromboembolism Among Men with and Without Hypogonadism
12 Nov, 2019 | 11:22h | UTCAssociation of Testosterone Therapy With Risk of Venous Thromboembolism Among Men With and Without Hypogonadism – JAMA Internal Medicine (free for a limited period)
Related Commentary on Twitter
Using testosterone therapy in 6-month case period associated with doubling of VTE risk for men both with and without clinical hypogonadism. https://t.co/rosKWgWgBS
— JAMA Internal Medicine (@JAMAInternalMed) November 11, 2019
[Abstract Only] Randomized Trial: Treatments for Relapsed or Refractory FLT3-mutated Acute Myeloid Leukemia Compared
10 Nov, 2019 | 12:57h | UTCGilteritinib or Chemotherapy for Relapsed or Refractory FLT3-Mutated AML – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: ADMIRAL: Gilteritinib vs Chemotherapy in Relapsed or Refractory FLT3-Mutated AML – The ASCO Post (free)
Randomized Trial: Levofloxacin Prophylaxis Reduces Early Deaths in Patients with Newly Diagnosed Myeloma
30 Oct, 2019 | 08:17h | UTCCommentaries: Reducing infection-related morbidity and mortality in patients with myeloma – The Lancet Oncology (free) AND Abx Prophylaxis Cuts Early Death in Newly Diagnosed Myeloma – MedPage Today (free)
Randomized Trial: Treatment vs. Observation in Smoldering Multiple Myeloma
30 Oct, 2019 | 08:15h | UTCCommentary: Lenalidomide may delay onset of myeloma-related bone, organ damage – Mayo Clinic (free)
[Abstract Only] Study: The Global Need and Availability of Blood Products
25 Oct, 2019 | 08:40h | UTCThe global need and availability of blood products: a modelling study – The Lancet Haematology (link to abstract – $ for full-text)
Commentaries: Hospitals Around The World Have A Dire Shortage Of Blood – NPR (free) AND 61% of countries have insufficient blood supplies – OnMedica (free)
Hemolytic Uremic Syndrome: Diagnosis and Management
23 Oct, 2019 | 07:24h | UTCHaemolytic uremic syndrome: diagnosis and management – F1000Research (free)
Source: Critical Care Reviews Newsletter
Randomized Trial: Fibrinogen Concentrate vs. Cryoprecipitate for the Treatment of Bleeding in Cardiac Surgery
22 Oct, 2019 | 07:36h | UTCEffect of Fibrinogen Concentrate vs Cryoprecipitate on Blood Component Transfusion After Cardiac Surgery: The FIBRES Randomized Clinical Trial – JAMA (free for a limited period)
Editorial: Should Fibrinogen Concentrate Replace Cryoprecipitate in Cardiac Surgery? (free for a limited period)
[Abstract Only] Randomized Trial: DOAC Not as Good as Vitamin K Antagonist for Anticoagulation in Antiphospholipid Syndrome
15 Oct, 2019 | 10:32h | UTCRivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries: Rivaroxaban Not Noninferior to VKAs for Antiphospholipid Antibody Syndrome – NEJM Journal Watch (free) AND DOAC Disappoints in Thrombotic Autoimmune Disorder – MedPage Today (free registration required)
Consensus Statement for the Diagnosis and Evaluation of Adult Patients With Histiocytic Neoplasms
10 Oct, 2019 | 09:08h | UTC