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Hematology (all articles)

[Abstract Only] Observational Study Suggests Apixaban May Be a Better Choice than Rivaroxaban for Patients with Atrial Fibrillation

11 Mar, 2020 | 08:20h | UTC

Effectiveness and Safety of Apixaban Compared With Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)

Commentary: Choosing a DOAC? Apixaban May Have an Edge Over Rivaroxaban – TCTMD (free)

 


[Abstract Only] Study: Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation

28 Feb, 2020 | 08:18h | UTC

Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Higher Microbiota Diversity in Hematologic Cancer Treatment Could Lower Mortality Risk, Study Finds – AJMC (free) AND Gut Diversity Before HCT Predicts Survival in Blood Cancers – MedPage Today (free registration required)

 


[Abstract Only] Meta-Analysis of Observational Studies Suggests No Benefit from Oral Anticoagulation in Patients With Atrial Fibrillation on Long-Term Dialysis

26 Feb, 2020 | 07:00h | UTC

Oral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Dialysis – Journal of the American College of Cardiology (link to abstract – $ for full-text)

Commentary: Anticoagulation for Dialysis Patients with Atrial Fibrillation: No Benefit Seen – NEJM Journal Watch (free for a limited period)

 


[Abstract Only] Meta-Analysis: Lower vs. Standard INR Targets in Atrial Fibrillation

25 Feb, 2020 | 06:04h | UTC

Lower versus Standard INR Targets in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Thrombosis and Haemostasis (link to abstract – $ for full-text)

Source: EvidenceAlerts

 


[Not Published Yet] Randomized Trial: Improved Outcomes with Myeloablative Therapy Compared to Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes

23 Feb, 2020 | 21:17h | UTC

Myeloablative Therapy Prevails in AML Transplant Study – MedPage Today (free registration required)

Original Study Abstract: 11 – Long-Term Follow up of BMT CTN 0901, a Randomized Phase III Trial Comparing Myeloablative (MAC) to Reduced Intensity Conditioning (RIC) Prior to Hematopoietic Cell Transplantation (HCT) for Acute Myeloid Leukemia (AML) or Myelodysplasia (MDS) (MAvRIC Trial) – Presented at Transplantation and Cellular Therapy Meetings (free)

Original Report: Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes – Journal of Clinical Oncology (free)

 


[Abstract Only] Meta-Analysis: Clinical Pre‐test Probability Adjusted vs. Age‐adjusted D‐dimer Interpretation Strategy for DVT Diagnosis

20 Feb, 2020 | 08:36h | UTC

Clinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)

Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)

Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)

 


Tumor Lysis Syndrome in Patients with Chronic Lymphocytic Leukemia Treated with BCL-2 Inhibitors: Risk Factors, Prophylaxis, and Treatment Recommendations

18 Feb, 2020 | 08:04h | UTC

Tumour lysis syndrome in patients with chronic lymphocytic leukaemia treated with BCL-2 inhibitors: risk factors, prophylaxis, and treatment recommendations – The Lancet Haematology (free registration required)

 


Immunization Strategies to Span the Spectrum of Immunocompromised Adults

16 Feb, 2020 | 20:43h | UTC

Immunization Strategies to Span the Spectrum of Immunocompromised Adults – Mayo Clinic Proceedings (free)

 


Study: Lower GI-bleeding in Anticoagulated Patients with Atrial Fibrillation Should Always Raise Suspicion of Colorectal Cancer

9 Feb, 2020 | 20:47h | UTC

Gastrointestinal bleeding and the risk of colorectal cancer in anticoagulated patients with atrial fibrillation – European Heart Journal (free)

Commentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)

 


Review: How I Treat Cancer-associated Thrombosis

9 Feb, 2020 | 20:18h | UTC

How I treat cancer-associated thrombosis – ESMO Open (free)

Related: ASCO Guideline: Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer (free)

 


European Consensus Recommendation: Prophylaxis and Management of GVHD after Stem-cell Transplantation for Hematological Malignancies

2 Feb, 2020 | 19:51h | UTC

Prophylaxis and management of graft versus host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation – The Lancet Haematology (free registration required)

 


A Network Meta-analysis of Maintenance Therapy in Chronic Lymphocytic Leukemia

31 Jan, 2020 | 00:54h | UTC

A network meta-analysis of maintenance therapy in chronic lymphocytic leukemia – PLOS One (free)

 


BSH Guideline: Laboratory Diagnosis of G6PD Deficiency

30 Jan, 2020 | 07:36h | UTC

Laboratory diagnosis of G6PD deficiency. A British Society for Haematology Guideline – British Journal of Haematology (free)

 


Sickle Cell Disease: A Primary Care Update

30 Jan, 2020 | 07:32h | UTC

Sickle cell disease: A primary care update – Cleveland Clinic Journal of Medicine (free)

 


ASH Guidelines for Sickle Cell Disease: Transfusion Support

29 Jan, 2020 | 08:27h | UTC

American Society of Hematology 2020 guidelines for sickle cell disease: transfusion support – Blood Advances (free)

 


Meta-Analysis of Direct Oral Anticoagulants Randomized Trials: Double vs. Triple Antithrombotic Therapy in Patients with Atrial Fibrillation Following Percutaneous Coronary Intervention

22 Jan, 2020 | 09:28h | UTC

Safety and efficacy outcomes of double vs. triple antithrombotic therapy in patients with atrial fibrillation following percutaneous coronary intervention: a systematic review and meta-analysis of non-vitamin K antagonist oral anticoagulant-based randomized clinical trials – European Heart Journal (free)

Related: Meta-analysis: Double Anti-thrombotic Therapy Safer than Triple Therapy in Patients with Atrial Fibrillation and Coronary Artery Disease (studies on the subject)

 


[Abstract Only] Randomized Trial: Effects of Addition of Anti-thymocyte Globulin to Standard Graft-versus-host Disease Prophylaxis in Patients with Hematological Malignancies Undergoing Transplantation from Unrelated Donor

22 Jan, 2020 | 09:16h | UTC

Addition of anti-thymocyte globulin to standard graft-versus-host disease prophylaxis versus standard treatment alone in patients with haematological malignancies undergoing transplantation from unrelated donors: final analysis of a randomised, open-label, multicentre, phase 3 trial – The Lancet Haematology (link to abstract – $ for full-text)

 


Recommendations for Therapeutic Apheresis

21 Jan, 2020 | 01:10h | UTC

Recommendations for Therapeutic Apheresis by the Section “Preparative and Therapeutic Hemapheresis” of the German Society for Transfusion Medicine and Immunohematology – Transfusion Medicine and Hemotherapy (free)

 


Addendum to BSH Guidelines on Investigation and Management of Antiphospholipid Syndrome: Use of Direct Acting Oral Anticoagulants

19 Jan, 2020 | 20:55h | UTC

Addendum to British Society for Haematology Guidelines on Investigation and Management of Antiphospholipid syndrome, 2012 (Br. J. Haematol. 2012; 157: 47–58): use of direct acting oral anticoagulants – British Journal of Haematology (free)

Related: Randomized Trial: DOAC Not as Good as Vitamin K Antagonist for Anticoagulation in Antiphospholipid Syndrome (link to abstract and commentaries)

 


Cohort Study: Incidental Lymphopenia and Mortality

19 Jan, 2020 | 20:45h | UTC

Incidental lymphopenia and mortality: a prospective cohort study – Canadian Medical Association Journal (free)

Commentaries:  Lymphopenia may hint a higher risk of future illness, death – News Medical (free) AND Incidental Low Lymphocyte Count Linked to Increased Mortality – MedicalResearch.com (free)

 


Randomized Trial: Effect of Dasatinib vs. Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia

19 Jan, 2020 | 20:38h | UTC

Effect of Dasatinib vs Imatinib in the Treatment of Pediatric Philadelphia Chromosome–Positive Acute Lymphoblastic Leukemia: A Randomized Clinical Trial – JAMA Oncology (free for a limited period)

Commentary: Dasatinib Superior to Imatinib in Pediatric ALL – MedPage Today (free)

 


Randomized Trial: Twice-daily vs. Alternate-day Oral Iron Therapy in the Treatment of Iron-deficiency Anemia

16 Jan, 2020 | 03:23h | UTC

Randomized controlled trial of twice-daily versus alternate-day oral iron therapy in the treatment of iron-deficiency anemia – Annals of Hematology (free)

 


Review: Surveillance in Patients with Diffuse Large B Cell Lymphoma

15 Jan, 2020 | 01:07h | UTC

Surveillance in Patients with Diffuse Large B Cell Lymphoma – Mayo Clinic Proceedings (free)

 


Meta-Analysis: Multiple Drug Combinations of Bortezomib, Lenalidomide, and Thalidomide for First‐line Treatment in Adults with Transplant‐Ineligible Multiple Myeloma

15 Jan, 2020 | 00:54h | UTC

Multiple drug combinations of bortezomib, lenalidomide, and thalidomide for first‐line treatment in adults with transplant‐ineligible multiple myeloma: a network meta‐analysis – Cochrane Library (free)

Summary: Multiple drug combinations of bortezomib, lenalidomide and thalidomide for initial treatment of adults with transplant-ineligible multiple myeloma – Cochrane Library (free)

Commentary: Featured Review: Reducing uncertainties in choosing first-line treatment in newly diagnosed multiple myeloma – Cochrane Library (free)

 


ESMO Guideline: Marginal Zone Lymphomas

14 Jan, 2020 | 00:26h | UTC

Marginal zone lymphomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up – Annals of Oncology (free)

 


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