Hematology (all articles)
Case Reports: Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19
9 Apr, 2020 | 03:20h | UTC
Study: Convalescent Plasma Therapy in Severe COVID-19 Patients
7 Apr, 2020 | 04:14h | UTCRelated Studies: Treatment with convalescent plasma for critically ill patients with SARS-CoV-2 infection – CHEST AND Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA
COVID-19: Thrombosis, Coagulopathy and Disseminated Intravascular Coagulation
6 Apr, 2020 | 01:42h | UTCGuidelines: Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK AND ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis
Observational Studies: Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis AND Abnormal Coagulation parameters are associated with poor prognosis in patients with novel coronavirus pneumonia – Journal of Thrombosis and Haemostasis (free PDF)
Q & A: COVID-19 and Coagulopathy: Frequently Asked Questions – American Society of Hematology
Podcast: A Practical Approach to Lymphadenopathy
3 Apr, 2020 | 03:54h | UTC#202 LIVE! Lymphadenopathy: Taking Your Lumps – The Curbsiders Internal Medicine Podcast
See also: Episode List
Treatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma
30 Mar, 2020 | 02:12h | UTCTreatment of 5 Critically Ill Patients With COVID-19 With Convalescent Plasma – JAMA
Editorial: Convalescent Plasma to Treat COVID-19: Possibilities and Challenges
Commentaries: A new report raises hope that the blood of recovered patients can help treat severe coronavirus cases – Business Insider AND Plasma transfusion shows promise for COVID-19 treatment, says China study – UPI
See also: Investigational COVID-19 Convalescent Plasma – Emergency INDs – U.S. Food & Drug Administration
#ACC20 – [Abstract only] Randomized Trial: Rivaroxaban or Enoxaparin in Nonmajor Orthopedic Surgery
30 Mar, 2020 | 01:20h | UTCRivaroxaban or Enoxaparin in Nonmajor Orthopedic Surgery – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: PRONOMOS: Rivaroxaban Better Than Enoxaparin in Preventing VTE After Nonmajor Orthopedic Surgery – American College of Cardiology (free) AND PROphylaxis in NON-Major Orthopedic Surgery – PRONOMOS – American College of Cardiology (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)
#ACC20 – [Abstract Only] Randomized Trial: Anticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation
30 Mar, 2020 | 01:13h | UTCAnticoagulation with or without Clopidogrel after Transcatheter Aortic-Valve Implantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Antithrombotic Therapy After Transcatheter Aortic Valve Implantation in Patients With a Long-Term Indication for Oral Anticoagulation – POPular TAVI – American College of Cardiology (free)AND A-fib Patients Undergoing TAVR Do Better With OAC Alone: POPular TAVI – TCTMD (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)
#ACC20 – [Abstract Only] Randomized Trial: Rivaroxaban in Peripheral Artery Disease after Revascularization
30 Mar, 2020 | 01:05h | UTCRivaroxaban in Peripheral Artery Disease after Revascularization – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: VOYAGER-PAD: Rivaroxaban Associated With Reduced Adverse Limb, CV Events in PAD Patients – American College of Cardiology (free) AND VOYAGER PAD: Rivaroxaban Bests Aspirin Alone for Preventing Limb and CV Events – TCTMD (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)
#ACC20 – [Abstract Only] Apixaban for the Treatment of Venous Thromboembolism Associated with Cancer
30 Mar, 2020 | 01:12h | UTCApixaban for the Treatment of Venous Thromboembolism Associated with Cancer – New England Journal of Medicine (abstract Only – $ for full-text)
Commentaries: Caravaggio Trial: Apixaban Noninferior to Dalteparin in Treatment of Cancer-Associated VTE – American College of Cardiology (free) AND Apixaban, Dalteprin Shown to Have Same Bleeding Risk in Patients With Cancer – AJMC (free)
Just Presented at the 2020 American College of Cardiology Virtual Meeting (free access)
WHO Guidance: Maintaining a Safe and Adequate Blood Supply During the Pandemic Outbreak of COVID-19
26 Mar, 2020 | 02:08h | UTC
COVID-19: Updates for Oncologists & Hematologists
25 May, 2020 | 00:01h | UTCOncology Guidelines
- Cancer Patient Management During the Covid-19 Pandemic – European Society of Medical Oncology
- Evidence-Based Guidelines for Management of Head and Neck Mucosal Malignancies during the COVID-19 Pandemic – Otolaryngology–Head and Neck Surgery (05/2020)
- Modifying Practices in GI Oncology in the Face of COVID-19: Recommendations From Expert Oncologists on Minimizing Patient Risk – JCO Oncology Practice (05/2020)
- Management of Lung Nodules and Lung Cancer Screening During the COVID-19 Pandemic: CHEST Expert Panel Report – Journal of the American College of Radiology (05/2020)
- A rapid review of evidence and recommendations from the SIOPE Radiation Oncology working group to help mitigate for reduced paediatric radiotherapy capacity during the COVID-19 pandemic or other crises – Radiotherapy and Oncology (05/2020)
Oncology Articles
- Summary of international recommendations in 23 languages for patients with cancer during the COVID-19 pandemic – The Lancet Oncology (05/2020)
- Management of Cancer Surgery Cases During the COVID-19 Pandemic: Considerations – Annals of Surgical Oncology (05/2020)
- To Do or Not to Do?—A Review of Cancer Surgery Triage Guidelines in COVID-19 Pandemic – Indian Journal of Surgical Oncology (05/2020)
- COVID-19 and Cancer: a Comprehensive Review – Current Oncology Reports (05/2020)
- Androgen-deprivation therapies for prostate cancer and risk of infection by SARSCoV-2: a population-based study (n=4532) – Annals of Oncology (05/2020)
- Palliative Care for Patients With Cancer in the COVID-19 Era – JAMA Oncology (05/2020)
- Managing patients with cancer during the COVID-19 pandemic: frontline experience from Wuhan – The Lancet Oncology (05/2020)
- Cancer patients and research during COVID-19 pandemic: A systematic review of current evidence – Critical Reviews in Oncology/Hematology (05/2020)
- Frequently asked questions regarding SARS-CoV-2 in cancer patients—recommendations for clinicians caring for patients with malignant diseases – Leukemia (05/2020)
- Bracing for impact with new 4R’s in the COVID-19 pandemic- a provincial thoracic radiation oncology consensus – Radiotherapy and Oncology (05/2020)
- Patients with cancer appear more vulnerable to SARS-COV-2: a multi-center study during the COVID-19 outbreak – Cancer Discovery AND Commentaries: COVID-19 Increases Overall Risk of Death, Complications in Patients With Cancer, Study Shows – AJMC AND Patients with blood and lung cancers are three times more at risk of dying of coronavirus than people with other tumors, study finds – Daily Mail AND Coronavirus: Cancer patients nearly three times more likely to die of Covid-19, study says – Independent (05/2020)
- Cancer Management in India during Covid-19 – New England Journal of Medicine (05/2020)
- COVID-19 in persons with haematological cancers – Leukemia (05/2020)
Hematologic Guidelines
- Association of Treatment Dose Anticoagulation with In-Hospital Survival Among Hospitalized Patients with COVID-19 – Journal of the American College of Cardiology
- Practical guidance for the management of adults with Immune Thrombocytopenia during the COVID‐19 pandemic – British Journal of Haematology (05/2020)
- Diagnosis, Prevention, and Treatment of Thromboembolic Complications in COVID-19: Report of the National Institute for Public Health of the Netherlands – Radiology (05/2020)
- Patient blood management during the COVID‐19 pandemic ‐ a narrative review – Anaesthesia (05/2020)
Hematology Articles
- NEW – Thromboembolism and anticoagulant therapy during the COVID-19 pandemic: interim clinical guidance from the anticoagulation forum – Journal of Thrombosis and Thrombolysis (05/2020)
- NEW – Thromboprophylaxis for medical inpatients with COVID-19 – Clinical Microbiology and Infection (05/2020)
- NEW – COVID-19 and coagulative axis: review of emerging aspects in a novel disease – Monaldi Archives for Chest Disease (05/2020)
- Coagulation abnormalities and thrombosis in patients with COVID-19 – The Lancet (05/2020)
- Understanding pathophysiology of hemostasis disorders in critically ill patients with COVID-19 – Intensive Care Medicine (05/2020)
- Pulmonary Arterial Thrombosis in COVID-19 With Fatal Outcome: Results From a Prospective, Single-Center, Clinicopathologic Case Series – Annals of Internal Medicine (05/2020)
- Care of Patients with Hemoglobin Disorders during the COVID-19 Pandemic: An Overview of Recommendations – American Journal of Hematology (05/2020)
- COVID-19 and ECMO: the interplay between coagulation and inflammation—a narrative review – Critical Care (05/2020)
- Lymphopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A systemic review and meta-analysis – International Journal of Infectious Diseases (05/2020)
- High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study – Intensive Care Medicine (05/2020)
- Coronavirus blood-clot mystery intensifies – Nature (05/2020)
- Arterial thromboembolic complications in COVID‐19 in low risk patients despite prophylaxis – British Journal of Haematology (05/2020)
- Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study – Annal of Internal Medicine (05/2020)
- Acute limb ischaemia in two young, non-atherosclerotic patients with COVID-19 – The Lancet (05/2020)
- Coagulopathy associated with COVID-19 – Canadian Medical Association Journal (05/2020)
- Hypercoagulation and Antithrombotic Treatment in Coronavirus 2019: A New Challenge – Thrombosis and Haemostasis (05/2020)
- Pulmonary Embolism or Pulmonary Thrombosis in COVID-19? Is the Recommendation to Use High-Dose Heparin for Thromboprophylaxis Justified? – Thrombosis and Haemostasis (05/2020)
- The resurgence of convalescent plasma therapy – The Lancet Haematology (05/2020)
- COVID-19 and its implications for thrombosis and anticoagulation – Blood (05/2020)
Guidelines:
- Prevention and Treatment of Venous Thromboembolism Associated with Coronavirus Disease 2019 Infection: A Consensus Statement before Guidelines – Thrombosis and Haemostasis (04/2020)
- Ethics and Resource Scarcity: ASCO Recommendations for the Oncology Community During the COVID19 Pandemic – American Society of Medical Oncology AND Commentary: ASCO Releases New Guidance on Allocation of Limited Resources in the Oncology Community During COVID-19 Pandemic – The ASCO Post (04/2020)
- Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 – Thrombosis UK (04/2020)
- ISTH interim guidance on recognition and management of coagulopathy – Journal of Thrombosis and Haemostasis (04/2020)
- Safety at the Time of the COVID-19 Pandemic: How to Keep our Oncology Patients and Healthcare Workers Safe – Journal of the National Comprehensive Cancer Network AND News Release: JNCCN: Improving COVID-19 safety for cancer patients and healthcare providers – National Comprehensive Cancer Network (04/2020)
- Practice recommendations for lung cancer radiotherapy during the COVID-19 pandemic: An ESTRO-ASTRO consensus statement – Radiotherapy and Oncology (04/2020)
- Recommendations for the surgical management of gynecological cancers during the COVID-19 pandemic – FRANCOGYN group for the CNGOF – Journal of Gynecology Obstetrics and Human Reproduction (04/2020)
- A Practical Approach to the Management of Cancer Patients During the Novel Coronavirus Disease 2019 (COVID-19) Pandemic: An International Collaborative Group – The Oncologist (04/2020)
- COVID-19 rapid guideline: delivery of systemic anticancer treatments – National Institute for Health and Care Excellence (03/2020)
- Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network (03/2020)
Articles:
- COVID‐19 Infection in Patients with Sickle Cell Disease – British Journal of Haematology (04/2020)
- COVID-19 and Cancer: Lessons From a Pooled Meta-Analysis – JCO Global Oncology AND Commentaries: Meta-analysis highlights COVID-19 risk in cancer patients, survivors – Medicine Matters (04/2020)
- Thrombosis and COVID-19: FAQs For Current Practice – American College of Cardiology (04/2020)
- COVID-19: impact on cancer workforce and delivery of care – The Lancet Oncology (04/2020)
- Caring for our cancer patients in the wake of COVID-19 – British Journal of Cancer (04/2020)
- D‐dimer levels on admission to predict in‐hospital mortality in patients with Covid‐19 – Journal of Thrombosis and Haemostasis (04/2020)
- Thrombocytopenia and Its Association with Mortality in Patients with COVID‐19 – Journal of Thrombosis and Haemostasis (04/2020)
- Caring for patients with cancer in the COVID-19 era – Nature Medicine AND Commentary: Caring for cancer patients in the COVID-19 era – Netherlands Cancer Institute (04/2020)
- COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-up – Journal of the American College of Cardiology AND Commentary: JACC Paper Outlines Implications, Considerations For Thrombotic Disease Patients During COVID-19 Pandemic – American College of Cardiology (04/2020)
- The Novel Coronavirus Disease (COVID-19) Threat for Patients with Cardiovascular Disease and Cancer – JACC CardioOncology (04/2020)
- Hematological findings and complications of COVID‐19 – American Journal of Hematology (04/2020)
- COVID-19 and Coagulopathy: Frequently Asked Questions – American Society of Hematology (04/2020)
- Immune Thrombocytopenic Purpura in a Patient with Covid-19 – New England Journal of Medicine (04/2020)
- Oncology Practice During the COVID-19 Pandemic – JAMA (04/2020)
- D-dimer cutoffs to predict thrombosis in COVID-19 – PulmCrit (04/2020)
- Caring for Patients With Cancer During the COVID-19 Outbreak in Italy – JAMA Oncology (04/2020)
- Strategy for the practice of digestive and oncological surgery during the Covid-19 epidemic – Journal of Visceral Surgery (04/2020)
- First statement on preparation for the COVID-19 pandemic in large German Speaking University-based radiation oncology departments – Radiation Oncology (04/2020)
- Testing the association between blood type and COVID-19 infection, intubation, and death – medRxiv (04/2020)
- Coagulopathy and Antiphospholipid Antibodies in Patients with Covid-19 – New England Journal of Medicine (04/2020)
- How we treat patients with lung cancer during the SARS-CoV-2 pandemic: primum non nocere – ESMO Open (04/2020)
- Cancer guidelines during the COVID-19 pandemic – The Lancet Oncology (04/2020)
- D-dimer is Associated with Severity of Coronavirus Disease 2019: A Pooled Analysis – Thrombosis and Haemostasis (04/2020)
- Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy – Journal of Thrombosis and Haemostasis (04/2020)
- Q & A: COVID-19 and Coagulopathy: Frequently Asked Questions – American Society of Hematology (04/2020)
- Clinical characteristics of COVID-19-infected cancer patients: A retrospective case study in three hospitals within Wuhan, China – Annals of Oncology (04/2020)
- A War on Two Fronts: Cancer Care in the Time of COVID-19 – Annals of Internal Medicine (03/2020)
- Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis – Clinica Chimica Acta (03/2020)
- Disseminated intravascular coagulation in patients with 2019‐nCoV pneumonia – Journal of Thrombosis and Haemostasia
- SARS-CoV-2 Transmission in Patients With Cancer at a Tertiary Care Hospital in Wuhan, China – JAMA Oncology AND Commentary: Cancer linked to increased COVID-19 risk – MedwireNews (03/2020)
- Cancer patients in SARS-CoV-2 infection: a nationwide analysis in China – The Lancet Oncology AND Commentaries: Risk of COVID-19 for patients with cancer – The Lancet Oncology AND Risk of COVID-19 for cancer patients – The Lancet Oncology (03/2020)
- Prominent changes in blood coagulation of patients with SARS-CoV-2 infection – Clinical Chemistry and Laboratory Medicine (03/2020)
- Clinical strategies for treating pediatric cancer during the outbreak of 2019 novel coronavirus infection – Pediatric Blood & Cancer (03/2020)
- Risk of COVID-19 for patients with cancer – The Lancet Oncology (03/2020)
- Thrombocytopenia is associated with severe coronavirus disease 2019 (COVID-19) infections: A meta-analysis – Clinica Chimica Acta
- Managing Cancer Care During the COVID-19 Pandemic: Agility and Collaboration Toward a Common Goal – Journal of the National Comprehensive Cancer Network (03/2020)
- How do we plan hematopoietic cell transplant and cellular therapy with the looming COVID‐19 threat? – British Journal of Haematology (03/2020)
News & Perspectives:
- The Blind Leading the Blind: COVID-19, Cancer, and the Need for More Data – ASCO Daily News (03/2020)
- Mitigating the Spread of COVID-19 and Its Impact on Cancer: How Cancer Centers Are Preparing for the Coronavirus – The ASCO Post (03/2020)
- The Treatment of Patients With Cancer and Containment of COVID-19: Experiences From Italy – ASCO Daily News (03/2020)
- Coronavirus means difficult, life-changing decisions for me and my cancer patients – The Guardian (03/2020)
COVID-19 Hemato-Oncology: This page will be updated as often as necessary and will be fixed in the right column on our homepage.
Position Statement on the Evaluation and Management of Patients with Cardiac Amyloidosis
13 Mar, 2020 | 07:59h | UTCCanadian Cardiovascular Society/Canadian Heart Failure Society Joint Position Statement on the Evaluation and Management of Patients With Cardiac Amyloidosis – Canadian Journal of Cardiology (free for a limited period)
[Abstract Only] Observational Study Suggests Apixaban May Be a Better Choice than Rivaroxaban for Patients with Atrial Fibrillation
11 Mar, 2020 | 08:20h | UTCEffectiveness and Safety of Apixaban Compared With Rivaroxaban for Patients With Atrial Fibrillation in Routine Practice: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentary: Choosing a DOAC? Apixaban May Have an Edge Over Rivaroxaban – TCTMD (free)
[Abstract Only] Study: Microbiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation
28 Feb, 2020 | 08:18h | UTCMicrobiota as Predictor of Mortality in Allogeneic Hematopoietic-Cell Transplantation – New England Journal of Medicine (link to abstract – $ for full-text)
Commentaries: Higher Microbiota Diversity in Hematologic Cancer Treatment Could Lower Mortality Risk, Study Finds – AJMC (free) AND Gut Diversity Before HCT Predicts Survival in Blood Cancers – MedPage Today (free registration required)
[Abstract Only] Meta-Analysis of Observational Studies Suggests No Benefit from Oral Anticoagulation in Patients With Atrial Fibrillation on Long-Term Dialysis
26 Feb, 2020 | 07:00h | UTCOral Anticoagulation for Patients With Atrial Fibrillation on Long-Term Dialysis – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Anticoagulation for Dialysis Patients with Atrial Fibrillation: No Benefit Seen – NEJM Journal Watch (free for a limited period)
[Abstract Only] Meta-Analysis: Lower vs. Standard INR Targets in Atrial Fibrillation
25 Feb, 2020 | 06:04h | UTCLower versus Standard INR Targets in Atrial Fibrillation: A Systematic Review and Meta-Analysis of Randomized Controlled Trials – Thrombosis and Haemostasis (link to abstract – $ for full-text)
Source: EvidenceAlerts
[Not Published Yet] Randomized Trial: Improved Outcomes with Myeloablative Therapy Compared to Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes
23 Feb, 2020 | 21:17h | UTCMyeloablative Therapy Prevails in AML Transplant Study – MedPage Today (free registration required)
Original Report: Myeloablative Versus Reduced-Intensity Hematopoietic Cell Transplantation for Acute Myeloid Leukemia and Myelodysplastic Syndromes – Journal of Clinical Oncology (free)
[Abstract Only] Meta-Analysis: Clinical Pre‐test Probability Adjusted vs. Age‐adjusted D‐dimer Interpretation Strategy for DVT Diagnosis
20 Feb, 2020 | 08:36h | UTCClinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis – Journal of Thrombosis and Haemostasis (link to abstract – $ for full-text)
Commentary: Clinical Pre-test Prob vs. Age-adjusted D-dimer for DVT – The Meta Analysis – JournalFeed (free)
Related Studies: Diagnosis of Pulmonary Embolism with d-Dimer Adjusted to Clinical Probability – New England Journal of Medicine (link to abstract and commentary) AND Age-Adjusted D-Dimer Cutoff Levels to Rule Out Pulmonary Embolism: The ADJUST-PE Study – JAMA (free)
Tumor Lysis Syndrome in Patients with Chronic Lymphocytic Leukemia Treated with BCL-2 Inhibitors: Risk Factors, Prophylaxis, and Treatment Recommendations
18 Feb, 2020 | 08:04h | UTCTumour lysis syndrome in patients with chronic lymphocytic leukaemia treated with BCL-2 inhibitors: risk factors, prophylaxis, and treatment recommendations – The Lancet Haematology (free registration required)
Immunization Strategies to Span the Spectrum of Immunocompromised Adults
16 Feb, 2020 | 20:43h | UTCImmunization Strategies to Span the Spectrum of Immunocompromised Adults – Mayo Clinic Proceedings (free)
Study: Lower GI-bleeding in Anticoagulated Patients with Atrial Fibrillation Should Always Raise Suspicion of Colorectal Cancer
9 Feb, 2020 | 20:47h | UTCCommentary: GI Bleeding and Colorectal Cancer Risk in Anticoagulated AF Patients – American College of Cardiology (free) AND GI bleeding often mistaken as side effect of blood thinners when it could indicate cancer – Cardiovascular Business (free)
Review: How I Treat Cancer-associated Thrombosis
9 Feb, 2020 | 20:18h | UTCHow I treat cancer-associated thrombosis – ESMO Open (free)
Related: ASCO Guideline: Venous Thromboembolism Prophylaxis and Treatment in Patients with Cancer (free)
European Consensus Recommendation: Prophylaxis and Management of GVHD after Stem-cell Transplantation for Hematological Malignancies
2 Feb, 2020 | 19:51h | UTCProphylaxis and management of graft versus host disease after stem-cell transplantation for haematological malignancies: updated consensus recommendations of the European Society for Blood and Marrow Transplantation – The Lancet Haematology (free registration required)
A Network Meta-analysis of Maintenance Therapy in Chronic Lymphocytic Leukemia
31 Jan, 2020 | 00:54h | UTCA network meta-analysis of maintenance therapy in chronic lymphocytic leukemia – PLOS One (free)
BSH Guideline: Laboratory Diagnosis of G6PD Deficiency
30 Jan, 2020 | 07:36h | UTC