Gynecology & Obstetrics (all articles)
Epidural-related maternal fever: incidence, pathophysiology, outcomes, and management
24 Mar, 2023 | 13:07h | UTCEpidural-related maternal fever: incidence, pathophysiology, outcomes, and management – American Journal of Obstetrics & Gynecology (free for a limited period)
Commentary on Twitter
AJOG Expert Review in Labor: Epidural-related maternal fever: incidence, pathophysiology, outcomes and management – Proposed mechanisms of sterile inflammation resulting in epidural-related maternal fever https://t.co/iTaQTKBlc3 pic.twitter.com/z0yrxzoMlh
— AJOG (@AJOG_thegray) March 19, 2023
Study shows there is little evidence of heightened pregnancy risks for IVF-conceived parents
24 Mar, 2023 | 12:53h | UTCNews Release: Little evidence that IVF conception heightens future pregnancy risks – BMJ Newsroom
Cohort Study | Association between motor vehicle crashes and adverse maternal outcomes in pregnancy
24 Mar, 2023 | 12:54h | UTCMaternal outcomes in association with motor vehicle crashes during pregnancy: a nationwide population-based retrospective study – Injury Prevention (link to abstract – full text may be available here)
News Release: Pregnant women in traffic collisions at heightened risk of birth complications – BMJ Newsroom
Cohort Study | Opioid use for pain relief after birth appears to pose no significant risk to breastfed infants
23 Mar, 2023 | 13:08h | UTCSummary: This large study from Canada found that infants born to mothers prescribed opioids after delivery, mainly following a cesarean, are at no greater risk of harm shortly after birth than infants of mothers not prescribed opioids. This suggests that breastfeeding is likely safe for babies whose mothers are taking opioids for pain relief.
The study included 865,691 mother-infant pairs discharged from Ontario hospitals within seven days of delivery between September 2012 and March 2020. Researchers matched mothers who filled an opioid prescription within seven days of discharge to those who did not.
Among the infants admitted to the hospital within 30 days, 2,962 (3.5%) were born to mothers who filled an opioid prescription compared with 3,038 (3.5%) born to mothers who did not, showing that infants of mothers prescribed opioids were no more likely to be admitted to the hospital for any reason. These children were only marginally more likely to visit the emergency department in the subsequent 30 days, and no differences were found for other serious outcomes, including breathing problems or admission to a neonatal intensive care unit, and no infant deaths occurred.
Although the study has some limitations, the high initial breastfeeding rates in Canada (90%) and the consistency of the findings with the fact that millions of new mothers are prescribed opioids after delivery each year provide confidence in the conclusions.
Editorial: Opioid analgesia for breastfeeding mothers – The BMJ
News Release: Infants of mothers given opioids after birth are at low risk of harm – BMJ Newsroom
RCT | Fezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause
23 Mar, 2023 | 13:01h | UTCFezolinetant for treatment of moderate-to-severe vasomotor symptoms associated with menopause (SKYLIGHT 1): a phase 3 randomised controlled study – The Lancet (link to abstract – $ for full-text)
Commentary on Twitter (thread – click for more)
70% of women experience hot flushes or night sweats during #menopause.
A new study investigates the role Fezolinetant, a non-hormonal treatment, could play in reducing these symptoms. https://t.co/zv4b9WU03h
— The Lancet (@TheLancet) March 15, 2023
Cohort Study | Infertility in women linked to increased risk of cardiovascular disease
23 Mar, 2023 | 12:39h | UTC
Commentary on Twitter
Women with infertility may have greater risk of #coronary #heart #disease, especially those diagnosed with #ovulation disorders/#endometriosis. #AHAJournals #GoRedforWomen @l_farland https://t.co/Izaloav4Np pic.twitter.com/Iqn4eQexJL
— JAHA (@JAHA_AHA) February 27, 2023
Review | The evolution of the labor curve and its implications for clinical practice
22 Mar, 2023 | 13:25h | UTCThe evolution of the labor curve and its implications for clinical practice: the relationship between cervical dilation, station, and time during labor – American Journal of Obstetrics & Gynecology (free for a limited period)
Commentary on Twitter
AJOG Expert Review in Labor: The evolution of the labor curve and its implications for clinical practice: the relationship between cervical dilation, station, and time during labor https://t.co/oUU9eGuFuo pic.twitter.com/YgAR1Zc93r
— AJOG (@AJOG_thegray) March 21, 2023
M-A | Maternal and neonatal complications following Kielland’s rotational forceps delivery
22 Mar, 2023 | 13:17h | UTC
Comparative study highlights women’s lower susceptibility to sudden cardiac arrest during sports
21 Mar, 2023 | 13:44h | UTCSummary: This study assessed the incidence, characteristics, and outcomes of sports-related sudden cardiac arrest (Sr-SCA) in women. Data from three European registries were analyzed, identifying 34,826 SCA cases between 2006 and 2017, with 760 cases (2.2%) being Sr-SCA, including 54 in women.
The average annual incidence of Sr-SCA in women was 0.19 per million, over 10 times lower than in men (2.63 per million). When extrapolated to the European population, this translates to 98 cases per year in women and 1,350 cases in men.
Characteristics, bystander response, time to defibrillation, and survival rates did not significantly differ between women and men. The findings highlight the considerably lower risk of Sr-SCA in women compared to men and should be considered when designing preparticipation screening strategies in the future.
Article: Incidence of Cardiac Arrest During Sports Among Women in the European Union – Journal of the American College of Cardiology (link to abstract – $ for full-text)
Commentary: Incidence of Cardiac Arrest During Sports Among Women – American College of Cardiology
Commentary on Twitter
Women are at very low risk of cardiac arrest during sports: incidence in women was calculated to be 13 times lower than in men in 3 European registries, w/ no differences in profile, circumstances, mgmt or outcomes. https://t.co/CLl6amlIHO#JACC #CardioTwitter #SportsCardio pic.twitter.com/ADpakbwUKt
— JACC Journals (@JACCJournals) March 15, 2023
Review | The sonopartogram
21 Mar, 2023 | 13:12h | UTCThe sonopartogram – American Journal of Obstetrics & Gynecology
Review | The latent phase of labor
20 Mar, 2023 | 13:28h | UTCThe latent phase of labor – American Journal of Obstetrics & Gynecology
Commentary on Twitter
AJOG Expert Review in Labor: The latent phase of labor- Management of a prolonged latent phase of labor https://t.co/ep0rPrldAn @acog @RCObsGyn @SOGCorg @ranzcog @ISUOG pic.twitter.com/fm7cUaQsOr
— AJOG (@AJOG_thegray) March 17, 2023
Cohort Study | Leukotriene-receptor antagonist use during pregnancy not linked to neuropsychiatric events in offspring
17 Mar, 2023 | 12:56h | UTCCommentary: In utero exposure to asthma medication not tied to risks of neurodevelopmental disorders – MDedge
SR | Planned hospital birth compared with planned home birth for pregnant women at low risk of complications
17 Mar, 2023 | 12:51h | UTCSummary: Planned hospital birth versus planned home birth – Cochrane Library
M-A | Prevalence of perinatal depression in low- and middle-income countries
17 Mar, 2023 | 12:49h | UTC
Commentary on Twitter
Depression amongst women, during pregnancy and up to a year postpartum, in low- and middle-income countries is common. Urgent action is required improve health outcomes for women and babies. https://t.co/xMSiqaOmiu @PerinatalEpi @mercyperinatal @UniMelb
— JAMA Psychiatry (@JAMAPsych) March 8, 2023
Cohort Study | Timing of antidepressant discontinuation during pregnancy and postpartum psychiatric outcomes
17 Mar, 2023 | 12:48h | UTC
Commentary on Twitter
A population-based study of 57,934 pregnant women in Denmark and Norway found that women who were previously stable antidepressant users but discontinued treatment late in pregnancy presented an elevated probability of postpartum initiating psycholeptics. https://t.co/k42OhXwgfi
— JAMA Psychiatry (@JAMAPsych) March 9, 2023
Study shows increased nuchal translucency can be ascertained using transverse planes
17 Mar, 2023 | 12:45h | UTC
Commentary on Twitter
Increased nuchal translucency can be ascertained using transverse planes https://t.co/WB2o7JvPug pic.twitter.com/yumS5sfvsN
— AJOG (@AJOG_thegray) December 2, 2022
FDA issues new information on cases of squamous cell carcinoma and lymphomas around breast implants
16 Mar, 2023 | 13:28h | UTCSummary: The US Food and Drug Administration (FDA) has provided an update on reports of squamous cell carcinoma (SCC) in the scar tissue (capsule) that forms around breast implants. The FDA is aware of 19 cases of SCC in the capsule around the breast implant from published literature, including 3 reports of deaths from the disease.
While the FDA continues to believe that occurrences of SCC in the capsule around the breast implant may be rare, the cause, incidence, and risk factors remain unknown. Health care providers and people who have or are considering breast implants should be aware that cases of SCC and various lymphomas in the capsule around the breast implant have been reported to the FDA and in the literature.
The FDA continues to ask health care providers and people with breast implants to report cases of SCC, lymphomas, or any other cancers around breast implants.
FDA Safety Communication: Reports of Squamous Cell Carcinoma (SCC) in the Capsule Around Breast Implants – FDA Safety Communication – U.S. Food & Drug Administration
Related:
FDA Report: 660 Cases of Breast Implant-Associated Anaplastic Large Cell Lymphoma
Study: Long-term Outcomes of Silicone Breast Implants
AACC Guidance document on cervical cancer detection: screening, surveillance, and diagnosis
16 Mar, 2023 | 13:21h | UTC
M-A | Maternal and infant outcomes of pregnancy associated with anti-SSA/RO antibodies
16 Mar, 2023 | 13:15h | UTC
Circulating microparticle proteins predict pregnancies complicated by placenta accreta spectrum
16 Mar, 2023 | 13:05h | UTCNews Release: Researchers Identify blood panel to predict placenta accreta – Brigham and Women’s Hospital
RCT | Insulin degludec is noninferior to insulin detemir for the treatment of pregnant women with type 1 diabetes
16 Mar, 2023 | 12:59h | UTCInsulin degludec versus insulin detemir, both in combination with insulin aspart, in the treatment of pregnant women with type 1 diabetes (EXPECT): an open‑label, multinational, randomised, controlled, non-inferiority trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Cohort Study | Risk of interpersonal violence during and after pregnancy among people with schizophrenia
16 Mar, 2023 | 12:56h | UTCNews Release: Pregnant people with schizophrenia have threefold risk of interpersonal violence – Canadian Medical Association Journal
Updated recommendations for the use of antiretroviral drugs during pregnancy and interventions to reduce perinatal HIV transmission
15 Mar, 2023 | 15:22h | UTC
Review | Diagnosis and management of endometriosis
15 Mar, 2023 | 15:19h | UTCDiagnosis and management of endometriosis – Canadian Medical Association Journal
M-A | Risk of recurrence and reintervention after uterine-sparing interventions for symptomatic adenomyosis
15 Mar, 2023 | 15:05h | UTC