Gynecology & Obstetrics (all articles)
M-A | The risk of long-term cardiometabolic disease in women with premature or early menopause
11 Apr, 2023 | 13:59h | UTC
RCT | Maternal RSVpreF vaccination protects infants from severe RSV illness
10 Apr, 2023 | 13:56h | UTCBivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in Infants – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Vaccination during pregnancy could prevent RSV illness in infants – Charité – Universitätsmedizin Berlin
Commentary on Twitter
In a phase 3 trial, adults (≥60 years of age) received one 120-μg dose of RSVpreF vaccine or placebo. Vaccine efficacy against RSV-associated lower respiratory tract illness was 67 to 86%. https://t.co/R9u77iWjF9 pic.twitter.com/iPU8VAMQ9M
— NEJM (@NEJM) April 5, 2023
Cohort Study | Long-term mortality in individuals diagnosed with cancer during pregnancy or postpartum
10 Apr, 2023 | 13:48h | UTCLong-term Mortality in Individuals Diagnosed With Cancer During Pregnancy or Postpartum – JAMA Oncology (free for a limited period)
Commentary on Twitter
Retrospective cohort study of 24,307 premenopausal women w/cancer shows higher risk of death w/pregnancy-assoc cancer than cancer remote from pregnancy, but results varied by site of cancer & in pregnancy vs. postpartum. https://t.co/7Eps4fUfLS
— JAMA Oncology (@JAMAOnc) April 7, 2023
Review | Urinary incontinence and pelvic organ prolapse in women
10 Apr, 2023 | 13:27h | UTC
SR | Insufficient evidence on skin-sparing mastectomy efficacy and safety for breast cancer
6 Apr, 2023 | 13:04h | UTCSkin‐sparing mastectomy for the treatment of breast cancer – Cochrane Database of Systematic Reviews
Cohort Study | Maternal cardiac arrest: occurrence, survival, and influencing factors
6 Apr, 2023 | 12:59h | UTCCardiac Arrest During Delivery Hospitalization: A Cohort Study – Annals of Internal Medicine (link to abstract – $ for full-text)
Commentaries:
Cardiac Arrest During Delivery Hospitalization – American College of Cardiology
Cardiac Arrest During Childbirth Is Rare, But Some Women Face Higher Risks – HealthDay
Commentary on Twitter
Study of pregnant women hospitalized during delivery found #CardiacArrest occurred in 1 in 9k deliveries, higher than other reported rates. More common in older or Black patients or persons w/ #Medicare or underlying conditions: https://t.co/ko1K7NFaPi. @CDCgov pic.twitter.com/23CxVi138k
— Annals of Int Med (@AnnalsofIM) March 15, 2023
SR | Induction of labor at or near term for suspected fetal macrosomia
6 Apr, 2023 | 12:55h | UTC
WHO Report | 1 in 6 people globally affected by infertility
5 Apr, 2023 | 13:47h | UTCNews Release: 1 in 6 people globally affected by infertility – World Health Organization
Report: Infertility Prevalence Estimates, 1990–2021 – World Health Organization
Key facts: Infertility – World Health Organization
Commentaries:
Infertility affects a ‘staggering’ 1 in 6 people worldwide, WHO says – CNN
One in six people worldwide affected by infertility, WHO reports – The Guardian
Commentary on Twitter (thread – click for more)
Around 1 in 6 people is affected by infertility in their lifetime: ? WHO research.
This shows an urgent need to increase access to affordable, high-quality fertility care https://t.co/od9QQ9Qjvj pic.twitter.com/R8JtezT0kZ
— World Health Organization (WHO) (@WHO) April 4, 2023
ACC/AHA blood pressure categories | Systematic review of adverse pregnancy outcomes in early pregnancy
6 Apr, 2023 | 12:53h | UTC
Commentary on Twitter
American College of Cardiology and American Heart Association blood pressure categories—a systematic review of the relationship with adverse pregnancy outcomes in the first half of pregnancy https://t.co/n3jWFLVYg5 pic.twitter.com/QzaWRyY4n5
— AJOG (@AJOG_thegray) March 31, 2023
M-A | Impact of antihypertensive therapy on maternal & neonatal outcomes in mild-moderate pregnancy hypertension
6 Apr, 2023 | 12:51h | UTC
Cohort Study | Pregnancy glucose intolerance, even below diabetes criteria, linked to increased risk of type 2 diabetes
5 Apr, 2023 | 13:42h | UTCGlucose intolerance in pregnancy and risk of early-onset type 2 diabetes: a population-based cohort study – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
Review | Comprehensive care of women with genetic predisposition to breast and ovarian cancer
5 Apr, 2023 | 13:32h | UTC
M-A | Vaginal swab outperforms urine for detection of Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis
5 Apr, 2023 | 13:23h | UTC
Consensus Paper | Definition and criteria for diagnosing cesarean scar disorder
5 Apr, 2023 | 12:51h | UTCDefinition and Criteria for Diagnosing Cesarean Scar Disorder – JAMA Network Open
M-A | Evolution and refinement of magnetically guided sentinel lymph node detection in breast cancer
4 Apr, 2023 | 13:30h | UTC
SR | Adding ultrasound to mammography increases breast cancer detection, but increases false-positives and biopsies
3 Apr, 2023 | 13:55h | UTCSummary: The systematic review examined the effectiveness and safety of combining mammography with breast ultrasonography versus mammography alone for breast cancer screening in women at average risk. The research included one randomized controlled trial, two prospective cohort studies, and five retrospective cohort studies, involving a total of 209,207 women.
High certainty evidence from one trial indicated that combining mammography with ultrasonography led to the detection of more breast cancer cases than mammography alone (5 vs. 3 per 1000 women). However, this combination also led to a higher number of false-positive results and biopsies. For every 1000 women screened with the combined approach, 37 more received a false-positive result, and 27 more women underwent a biopsy.
Secondary analysis of the trial data revealed that in women with dense breasts, the combined screening detected more cancer cases than mammography alone, while cohort studies for women with non-dense breasts showed no statistically significant difference between the two screening methods.
The included studies did not analyze whether the higher number of detected cancers with the combined screening method resulted in lower mortality rates compared to mammography alone. Further research, including randomized controlled trials or prospective cohort studies with longer observation periods, is needed to assess the impact of the two screening interventions on morbidity and mortality.
Review | Dysfunctional labor and delivery: adverse effects on offspring
3 Apr, 2023 | 13:36h | UTCDysfunctional labor and delivery: adverse effects on offspring – American Journal of Obstetrics & Gynecology (free for a limited period)
Glomerular diseases in pregnancy: pragmatic recommendations for clinical management
3 Apr, 2023 | 13:29h | UTC
Perspective | Should case management be considered a component of obstetrical interventions for pregnancies at risk of preterm birth?
3 Apr, 2023 | 13:18h | UTC
Commentary on Twitter
Should case management be considered a component of obstetrical interventions for pregnancies at risk of preterm birth? https://t.co/PpE23OIr5E pic.twitter.com/Ta7kdcFXmc
— AJOG (@AJOG_thegray) March 30, 2023
RCT | Early postpartum IUD placement noninferior vs. placement at 6-8 weeks for complete expulsion, but not for partial expulsion
31 Mar, 2023 | 13:48h | UTCEarly vs Interval Postpartum Intrauterine Device Placement: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
News Release: Study: Risk of IUD Expulsion in Early Postpartum Placement – UC San Diego Health
Commentary: IUD Placement at Two to Four Weeks Postpartum Noninferior – HealthDay
Related:
Commentary on Twitter
Early IUD placement at 2 to 4 weeks postpartum compared with 6 to 8 weeks postpartum was noninferior for complete expulsion, but not partial expulsion. https://t.co/VMfWce3JJd pic.twitter.com/vdLrhCXa5Q
— JAMA (@JAMA_current) March 23, 2023
M-A | Impact of axillary lymph node dissection and sentinel lymph node biopsy on upper limb morbidity in breast cancer patients
31 Mar, 2023 | 13:30h | UTC
Study shows a slight breast cancer risk increase with progestogen-only birth control, comparable to combined oral methods
29 Mar, 2023 | 13:35h | UTCSummary: A UK study and meta-analysis examined breast cancer risk linked to hormonal contraceptives, emphasizing progestagen-only contraceptives in premenopausal women. Utilizing a nested case-control design with the Clinical Practice Research Datalink (CPRD), a primary care database, the study included 9,498 women under 50 diagnosed with invasive breast cancer between 1996 and 2017, and 18,171 closely matched controls. The meta-analysis merged CPRD findings with 12 observational studies on progestagen-only preparations.
The results revealed that current or recent use of combined oral contraceptives, oral progestagen-only contraceptives, injectable progestagen, and progestagen intrauterine devices all led to a similar increase in breast cancer risk. The 15-year absolute excess risk associated with five years of oral combined or progestagen-only contraceptive use ranged from 8 per 100,000 users aged 16-20 to 265 per 100,000 users aged 35-39. The study concluded that both contraceptive types were linked to a slight breast cancer risk increase, and these risks must be weighed against the benefits of contraceptive use during childbearing years.
News Release: Study finds similar association of progestogen-only and combined hormonal contraceptives with breast cancer risk – PLOS
SR | Effect of antenatal corticosteroid administration-to-birth interval on maternal and newborn outcomes
29 Mar, 2023 | 13:22h | UTC
FIGO Good Practice Recommendations on the use of progesterone in the management of recurrent first-trimester miscarriage
29 Mar, 2023 | 13:20h | UTC
Consensus Statement | Management of vaginal intraepithelial neoplasia
28 Mar, 2023 | 14:37h | UTC