Gynecology & Obstetrics (all articles) | Page 49 of 86 | Links Medicus Content Curation & Alerts in Medicine

Neoadjuvant #chemotherapy makes breast conservation possible in half of patients with stages II to III TNBC who would have otherwise required #mastectomy https://t.co/ftcVdmj9RL @MehraGolshan

— JAMA Surgery (@JAMASurgery) January 8, 2020

[Abstract Only] Study: Sustained Weight Loss Linked to Lower Risk of Breast Cancer

8 Jan, 2020 | 22:20h | UTC

Sustained weight loss and risk of breast cancer in women ≥50 years: a pooled analysis of prospective data – JNCI: Journal of the National Cancer Institute (link to abstract – $ for full-text)

Commentaries: Large study links sustained weight loss to reduced breast cancer risk – American Cancer Society (free) AND Weight loss linked to lower chance of getting breast cancer for women over 50 – NHS Choices (free) AND Study Links Sustained Weight Loss to Reduced Breast Cancer Risk – The ASCO Post (free)

Randomized Trial: Long-term Aromatase Inhibitor Prevents Breast Cancer in High-risk Postmenopausal Women

8 Jan, 2020 | 21:48h | UTC

Use of anastrozole for breast cancer prevention (IBIS-II): long-term results of a randomised controlled trial – The Lancet (free)

Commentaries: IBIS-II study finds anastrozole reduces breast cancer rates for high risk postmenopausal women – Queen Mary, University of London (free) AND Drug that prevents half of breast cancers carries on working – BBC (free) AND Long-Term Results of IBIS-II: Anastrozole for Breast Cancer Prevention – The ASCO Post (free)

Study: Prevalence of Potentially Unnecessary Bimanual Pelvic Examinations and Papanicolaou Tests Among Adolescent Girls and Young Women Aged 15-20 Years

8 Jan, 2020 | 08:44h | UTC

Prevalence of Potentially Unnecessary Bimanual Pelvic Examinations and Papanicolaou Tests Among Adolescent Girls and Young Women Aged 15-20 Years in the United States – JAMA Internal Medicine (free for a limited period)

Commentaries: Unnecessary Bimanual Pelvic Examinations and Papanicolaou Testing in Adolescents and Young Women—Learning How to Unlearn – JAMA Internal Medicine (free for a limited period) AND Young women still may be getting unnecessary pelvic exams – University of California – San Francisco (free) AND Many young women get unnecessary pelvic exams – Reuters (free)

[Abstract Only] Randomized Trial: Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer

8 Jan, 2020 | 00:51h | UTC

Tucatinib, Trastuzumab, and Capecitabine for HER2-Positive Metastatic Breast Cancer – New England Journal of Medicine (free)

Commentaries: SABCS 2019: Adding Tucatinib to Capecitabine/Trastuzumab Improved Survival for Patients With Advanced HER2-Positive Breast Cancer – The ASCO Post (free) AND HER2CLIMB and DESTINY-Breast01 Findings in Heavily Pretreated HER2-positive MBC – ESMO (free)

[Abstract Only] Randomized Trial: Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer

8 Jan, 2020 | 00:51h | UTC

Overall Survival with Ribociclib plus Fulvestrant in Advanced Breast Cancer – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Targeted therapy drug helps women with aggressive breast cancer live longer – University of California (free) AND Overall Survival With the Addition of Ribociclib to Fulvestrant in Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer: MONALEESA-3 – The ASCO Post (free)

Study: Google Artificial Intelligence Algorithm Improves Accuracy of Breast Cancer Detection in Mammography

5 Jan, 2020 | 14:14h | UTC

International evaluation of an AI system for breast cancer screening – Nature (free link via STAT)

Commentaries: AI shows promise for breast cancer screening – Nature (free) AND Google AI tool can pinpoint breast cancer better than clinicians, new study suggests – STAT (free) AND Artificial intelligence could help to spot breast cancer – Imperial College London (free) AND AI can now outperform doctors at detecting breast cancer. Here’s why it won’t replace them – Vox (free) AND A.I. Is Learning to Read Mammograms – The New York Times (10 articles per month are free) AND Study finds Google system could improve breast cancer detection – Reuters (free)

Another Observational Study Suggests One Dose of HPV Vaccine may be Enough

5 Jan, 2020 | 13:25h | UTC

Prevalence of Human Papillomavirus Infection by Number of Vaccine Doses Among US Women – JAMA Network Open (free)

Commentaries: One dose of HPV vaccine may prevent infection from cancer-causing virus, study reveals – News Medical (free) AND Just 1 dose of the HPV vaccine may protect against infection, new study suggests – CNN (free)

[Abstract Only] Randomized Trial: Accelerated Partial Breast Irradiation vs. Whole-breast Irradiation After Breast-conserving Surgery for Early-stage Breast Cancer

5 Jan, 2020 | 13:05h | UTC

Long-term primary results of accelerated partial breast irradiation after breast-conserving surgery for early-stage breast cancer: a randomised, phase 3, equivalence trial – The Lancet (link to abstract – $ for full-text)

Related Commentary on Twitter

PRESS RELEASE: Accelerated Partial Breast Irradiation Although Close was Not Equivalent to Whole-breast Irradiation to Control Ipsilateral Breast Tumor Recurrence https://t.co/mCvuC5aeag #breastcancer pic.twitter.com/KRXAAtAjbj

— NRG Oncology (@NRGonc) December 6, 2019

[Abstract Only] Randomized Trial: External Beam Accelerated Partial Breast Irradiation vs. Whole Breast Irradiation after Breast Conserving Surgery in Women with Ductal Carcinoma in Situ and Node-negative Breast Cancer

5 Jan, 2020 | 13:08h | UTC

External beam accelerated partial breast irradiation versus whole breast irradiation after breast conserving surgery in women with ductal carcinoma in situ and node-negative breast cancer (RAPID): a randomised controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary: Results mixed for twice-daily APBI in early breast cancer – MedicalXpress (free)

Related Commentary on Twitter

NEW: External beam accelerated partial breast irradiation was non-inferior to whole breast irradiation in preventing ipsilateral breast tumour recurrence: finding from the RAPID randomised controlled trial https://t.co/4aexxXC8Vg pic.twitter.com/JMa0jUWY1X

— The Lancet (@TheLancet) December 6, 2019

NICE Guideline: Menopause

6 Dec, 2019 | 10:50h | UTC

Menopause: diagnosis and management – National Institute for Health and Care Excellence (free)

ASH Guideline: Prevention of Venous Thromboembolism in Surgical Hospitalized Patients

5 Dec, 2019 | 11:29h | UTC

American Society of Hematology 2019 guidelines for management of venous thromboembolism: prevention of venous thromboembolism in surgical hospitalized patients – Blood Advances (free)

Cohort Study: Maternal Diabetes During Pregnancy Linked to Early Onset of Cardiovascular Disease in Offspring

5 Dec, 2019 | 10:45h | UTC

Maternal diabetes during pregnancy and early onset of cardiovascular disease in offspring: population based cohort study with 40 years of follow-up – The BMJ (free)

Commentaries: Link between diabetes in mothers and heart disease in children – OnMedica (free) AND Preventing and treating diabetes in women of childbearing age could reduce heart disease risk in the next generation – The BMJ Opinion (free)

[Abstract Only] Cohort Study: Hair Dye and Chemical Straightener Associated with Increased Risk of Breast Cancer

5 Dec, 2019 | 07:49h | UTC

Hair dye and chemical straightener use and breast cancer risk in a large US population of black and white women – International Journal of Cancer (link to abstract – $ for full-text)

Commentaries: Permanent hair dye and straighteners may increase breast cancer risk – NIH News Releases (free) AND Hair Dyes And Straighteners Linked To Higher Cancer Risk, Especially For Black Women – NPR (free)

Randomized Trial: Synchronous vs. Sequential Chemo-radiotherapy in Patients with Early Stage Breast Cancer

4 Dec, 2019 | 08:17h | UTC

Synchronous versus sequential chemo-radiotherapy in patients with early stage breast cancer (SECRAB): A randomised, phase III, trial – Radiation & Oncology (free)

AAP Policy Statement: Emergency Contraception

3 Dec, 2019 | 08:15h | UTC

Emergency Contraception – Pediatrics (free)

Related: Committee Opinion No 707: Access to Emergency Contraception – American College of Obstetricians and Gynecologists (free) AND Interventions for emergency contraception – Cochrane Library (free)

[Abstract Only] Randomized Trial: Supplemental MRI Screening vs. Usual Care with Mammography Only for Women with Extremely Dense Breast Tissue

28 Nov, 2019 | 10:39h | UTC

Supplemental MRI Screening for Women with Extremely Dense Breast Tissue – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Does MRI Screening Benefit Women With Extremely Dense Breasts? – U.S. News (free) AND Mixed Results With Mammo Plus MRI Screening – MedPage Today (free)

“The benefits need to be carefully weighed against the harms, as MRI examination is more expensive, and it requires the injection of a contrast agent into the body. MRI will also detect abnormalities that later turn out not to be breast cancer after all” (from U.S News)

Related Commentary on Twitter

In this randomized trial, women with extremely dense breast tissue were invited to undergo MRI screening or received only mammography during a 2-year screening period. https://t.co/tZmcappO00

— NEJM (@NEJM) November 27, 2019