Gynecology & Obstetrics (all articles)
Cohort Study | In utero exposure to ADHD medication does not seem to result in worse offspring neurodevelopmental outcomes
14 Feb, 2023 | 10:54h | UTCSummary: The authors conducted a study to investigate the long-term effects of in utero exposure to ADHD medication (methylphenidate, amphetamine, dexamphetamine, lisdexamphetamine, modafinil, atomoxetine, clonidine) on offspring. The study followed 1,068,073 liveborn singletons from 1998 to 2018 and compared the outcomes of children whose mothers continued or discontinued ADHD medication during pregnancy. The main outcomes were neurodevelopmental psychiatric disorders, impairments in vision or hearing, epilepsy, seizures, or growth impairment during childhood or adolescence. After adjustment for demographic and psychiatric characteristics of the mother, no increased risk of any developmental disorders was found in offspring exposed to ADHD medication compared to those not exposed. The results provide reassurance for women with ADHD who depend on medication and consider continuing it during pregnancy.
(By ChatGPT, reviewed and edited)
Article: In utero exposure to ADHD medication and long-term offspring outcomes – Molecular Psychiatry (link to abstract – $ for full-text)
Commentary from the author on Twitter (thread – click for more)
In-utero exposure to ADHD medication is not associated with long-term adverse neurodevelopmental disorders and growth restriction in the offspring.
Read the thread below 🧵on our new paper just published in @molpsychiatry
👉 https://t.co/MKZ0aeFnhU#ADHD— Kathrine Bang Madsen (@Kathrine_BaMa) February 9, 2023
Development of a model to estimate the optimal number of oocytes to attempt to fertilize in IVF
14 Feb, 2023 | 10:36h | UTC
Commentary on Twitter
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2799935
Stillbirth after adolescent and young adult cancer: a population-based study
14 Feb, 2023 | 10:33h | UTCCommentary: Previous Cancer Treatment Not Tied to Higher Stillbirth Rate – HealthDay
RCT | Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy
14 Feb, 2023 | 10:31h | UTC
Development of a machine learning model for sonographic assessment of gestational age
14 Feb, 2023 | 10:30h | UTCCommentary: AI Models Have Higher Accuracy for Estimating Gestational Age – HealthDay
RCT | Azithromycin reduces the risk of maternal sepsis or death in women planning a vaginal birth
13 Feb, 2023 | 13:02h | UTCAzithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth – New England Journal of Medicine (link to abstract – $ for full-text)
News Release: Single-dose antibiotic prevents maternal sepsis and death – NIH News
Commentaries:
In large study, a single antibiotic dose slashed rate of sepsis in childbirth – STAT
Dose of azithromycin found to cut risk of maternal death, sepsis in childbirth – CIDRAP
The Lancet Series | Breastfeeding 2023
13 Feb, 2023 | 12:52h | UTCHomepage: Breastfeeding 2023 – The Lancet
Editorial: Unveiling the predatory tactics of the formula milk industry
Breastfeeding: crucially important, but increasingly challenged in a market-driven world
Marketing of commercial milk formula: a system to capture parents, communities, science, and policy
Commentaries:
Expert reaction to review of formula baby milk – Science Media Centre
US infant pertussis incidence trends before and after implementation of the maternal Tdap vaccine
13 Feb, 2023 | 12:38h | UTCUS Infant Pertussis Incidence Trends Before and After Implementation of the Maternal Tetanus, Diphtheria, and Pertussis Vaccine – JAMA Pediatrics (free for a limited period)
Commentary: Maternal Tdap Vaccination Protects Youngest Infants From Pertussis – HealthDay
Commentary on Twitter
Study findings suggest that maternal #Tdap vaccination is associated with a reduction in #pertussis among infants younger than 2 months, the strategy’s target age group. https://t.co/a5h3z2zXY2
— JAMA Pediatrics (@JAMAPediatrics) February 7, 2023
Consensus Statement | Development of an Enhanced Recovery After Surgery (ERAS) surgical safety checklist
10 Feb, 2023 | 14:03h | UTC
Commentary from the author on Twitter (thread – click for more)
The @WHO Surgical Safety Checklist and the @ErasSociety guidelines come together.🔥
#ERAS teams can leverage 2 tools in 1 to improve care in critical perioperative communication moments https://t.co/EaXYyj7b56
via @JAMANetworkOpen part of @JAMANetwork pic.twitter.com/WHJMjThubO— Mary Brindle (@MaryEBrindle) February 8, 2023
POTS and Pregnancy: a review of literature and recommendations for evaluation and treatment
10 Feb, 2023 | 13:37h | UTC
Cohort Study | Adverse pregnancy outcomes and long-term risk of ischemic heart disease in mothers
9 Feb, 2023 | 14:02h | UTCNews Release: Five major adverse pregnancy outcomes associated with long term risks of ischemic heart disease – News Medical/BMJ
Commentary: Complications during pregnancy linked to a higher risk of heart disease, study finds – CNN
Related:
AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk
Cohort Study: Preeclampsia and Cardiovascular Disease
All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease
Gestational Hypertension and Future Risk of Cardiovascular Disease
RCT | Pregnancy and neonatal safety of PrEP for HIV prevention initiated during pregnancy vs. afterwards
9 Feb, 2023 | 13:55h | UTCPregnancy and neonatal safety outcomes of timing of initiation of daily oral tenofovir disoproxil fumarate and emtricitabine pre-exposure prophylaxis for HIV prevention (CAP016): an open-label, randomised, non-inferiority trial – The Lancet HIV (link to abstract – $ for full-text)
Guideline | Fetal monitoring in labor
9 Feb, 2023 | 13:48h | UTCFetal monitoring in labour – National Institute for Health and Care Excellence
Guideline | Intrapartum care for healthy women and babies
9 Feb, 2023 | 13:49h | UTCIntrapartum care for healthy women and babies – National Institute for Health and Care Excellence
Review | The role of MRI in the diagnosis and prognostic evaluation of fetuses with congenital diaphragmatic hernia
9 Feb, 2023 | 13:40h | UTC
RCT | Gefitinib plus MTX not better than MTX alone to treat tubal ectopic pregnancy
8 Feb, 2023 | 12:43h | UTC
Commentary from the author on Twitter (thread – click for more)
See our @Gem3Study in @TheLancet: no benefit of adding gefitinib to methotrexate to treat #ectopic pregnancy but important data to inform guidelines on clinical outcomes after methotrexate https://t.co/xgtA4oLBJd @ProfStephenTong @GynaeResearcher @TheEPT @MRC_CRH @EdinUniMedia pic.twitter.com/g96Z8B400a
— Andrew Horne (@horne_research) February 2, 2023
Under a Creative Commons Attribution (CC BY 4.0) license
RCT | Outcomes in children of women with type 2 diabetes exposed to metformin vs. placebo during pregnancy
8 Feb, 2023 | 12:32h | UTCOutcomes in children of women with type 2 diabetes exposed to metformin versus placebo during pregnancy (MiTy Kids): a 24-month follow-up of the MiTy randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)
M-A | Risk of endometrial cancer in postmenopausal women in relation to ultrasonographic endometrial thickness
8 Feb, 2023 | 12:21h | UTCRisk of endometrial cancer in asymptomatic postmenopausal women in relation to ultrasonographic endometrial thickness: systematic review and diagnostic test accuracy meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary on Twitter
AJOG Systematic Review: Risk of endometrial cancer in asymptomatic postmenopausal women in relation to ultrasonographic endometrial thickness: systematic review and diagnostic test accuracy meta-analysis https://t.co/uxPx8Jr160 pic.twitter.com/LugkrnKmjr
— AJOG (@AJOG_thegray) December 30, 2022
RCT | Laser no better than sham treatment for genitourinary syndrome of menopause
8 Feb, 2023 | 12:17h | UTCLaser versus sham for genitourinary syndrome of menopause: A randomised controlled trial – BJOG (link to abstract – $ for full-text)
Invited commentary: Laser therapy for genitourinary syndrome of menopause: Emperor’s new clothes or a meaningful advance? – BJOG
Related:
M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.
Perspective: From vaginal laser treatment to spa breaks – it’s the great menopause gold rush.
M-A | Risk of second primary cancer among breast cancer patients
6 Feb, 2023 | 13:10h | UTC
SR | Partial breast irradiation for breast cancer
3 Feb, 2023 | 14:06h | UTCPartial Breast Irradiation for Breast Cancer – Agency for Healthcare Research and Quality
M-A | Comparative effectiveness of prophylactic strategies for preeclampsia
2 Feb, 2023 | 14:42h | UTCComparative effectiveness of prophylactic strategies for preeclampsia: a network meta-analysis of randomized controlled trials – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary: Meta‐analysis reveals effective prophylactic strategies for preeclampsia – MDEdge
SR | Interventions to improve health and the determinants of health among sex workers in high-income countries
1 Feb, 2023 | 13:25h | UTCEditorial: Sex workers health: time to act
Commentary from the author on Twitter (thread – click for more)
New Paper! Our SR in @TheLancetPH summarises evidence for health & social interventions in sex worker populations in HICs https://t.co/TSe9qv4oKP Great team inc @DrLucypotter @MollyBradbury14 @GraceyOutreach @Kitdempsey @rob_aldridge @BintyRock @SerenaLuchenski🧵below…1/4 pic.twitter.com/P6Bx3rFfHw
— Luke Johnson, MD, MSc, FFPH (@luke_a_johnson) November 3, 2022
SR | Immediate breast reconstruction uptake in older women with primary breast cancer
1 Feb, 2023 | 13:04h | UTC
SR | Present and future of machine learning in breast surgery
1 Feb, 2023 | 13:03h | UTC
Commentary on Twitter
Open Access in BJS' November issue: Present and future of machine learning in breast surgery: systematic review https://t.co/mdE94BzOIt @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @paulo_sutt @robhinchliffe1 @young_bjs pic.twitter.com/XVPwgZaVIm
— BJS (@BJSurgery) November 20, 2022