Gynecology & Obstetrics (all articles)
Cohort Study | Contralateral breast cancer risk among carriers of germline pathogenic variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2
13 Jan, 2023 | 13:14h | UTC
RCT | Planned delivery for pre-eclampsia between 34 and 37 weeks of gestation
12 Jan, 2023 | 13:20h | UTCOriginal Publication: Planned early delivery or expectant management for late preterm pre-eclampsia (PHOENIX): a randomised controlled trial – The Lancet
RCT | Effect of pessary vs. surgery in patients with symptomatic pelvic organ prolapse
12 Jan, 2023 | 13:16h | UTCEffect of Pessary vs Surgery on Patient-Reported Improvement in Patients With Symptomatic Pelvic Organ Prolapse: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Findings question value of pessary for pelvic organ prolapse – MDedge
Commentary on Twitter
In this study, among patients with symptomatic pelvic organ prolapse, an initial strategy of pessary therapy, compared with surgery, did not meet criteria for noninferiority with regard to patient-reported improvement at 24 months. https://t.co/PRb7iclR8O pic.twitter.com/ex3SSmLqyz
— JAMA (@JAMA_current) December 20, 2022
SR | No-test medication abortion
10 Jan, 2023 | 14:02h | UTCNo-Test Medication Abortion: A Systematic Review – Obstetrics & Gynecology
Commentary on Twitter
From Shapiro et al: medication abortion performed without prior pelvic exam or ultrasound is safe and effective. #free #podcast https://t.co/xightukWW0 pic.twitter.com/P6bajuKZDU
— The Green Journal (@greenjrnl) December 21, 2022
WHO updates recommendations on HPV vaccination schedule
9 Jan, 2023 | 14:57h | UTCNews Release: WHO updates recommendations on HPV vaccination schedule – World Health Organization
Guideline: Human papillomavirus vaccines: WHO position paper, December 2022 – World Health Organization
Commentaries:
WHO supports 1-dose HPV vaccine strategy – CIDRAP
Commentary on Twitter
? WHO has revised its recommendations on possible schedules for human papillomavirus (#HPV) vaccines & now recommends:
?1 or 2-doses for girls & women aged 9-20
?2 doses with a 6-month interval for women 21+https://t.co/m0KZyH6sPR pic.twitter.com/W4PeS4raV9— World Health Organization (WHO) (@WHO) December 21, 2022
Review | Transmission of Group B Streptococcus in late-onset neonatal disease
9 Jan, 2023 | 14:05h | UTC
Review | Human papillomavirus vaccination and cervical cancer risk.
16 Dec, 2022 | 13:26h | UTCHuman papillomavirus vaccination and cervical cancer risk – The BMJ
Review | Pathophysiology, diagnosis, and management of endometriosis.
16 Dec, 2022 | 13:23h | UTCPathophysiology, diagnosis, and management of endometriosis – The BMJ
Post-trial follow-up | Radiotherapy vs. surgery of the axilla after a positive sentinel node in breast cancer.
14 Dec, 2022 | 14:42h | UTCRadiotherapy or Surgery of the Axilla After a Positive Sentinel Node in Breast Cancer: 10-Year Results of the Randomized Controlled EORTC 10981-22023 AMAROS Trial – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary: ART Preferred Over ALND in Sentinel Node-Positive Early Breast Cancer – Cancer Therapy Advisor
Cohort Study | Prenatal carbamazepine exposure and academic performance in adolescents.
13 Dec, 2022 | 14:22h | UTCPrenatal Carbamazepine Exposure and Academic Performance in Adolescents: A Population-Based Cohort Study – Neurology (link to abstract – $ for full-text)
RCT | Ropivacaine perineal infiltration after episiotomy did not reduce postpartum pain.
13 Dec, 2022 | 14:16h | UTCRopivacaine perineal infiltration for postpartum pain management in episiotomy repair: a double-blind, randomised, placebo-controlled trial – BJOG (link to abstract – $ for full-text)
RCT | Efficacy of single wound infiltration with bupivacaine and adrenaline during cesarean delivery for reduction of postoperative pain.
12 Dec, 2022 | 12:25h | UTC
Commentary on Twitter
RCT: Single wound infiltration with bupivacaine and adrenaline during cesarean delivery reduces postoperative pain scores and opioid use. The technique is safe & simple. https://t.co/SdYdrfMBQJ #OAResearch
— JAMA Network Open (@JAMANetworkOpen) November 15, 2022
Consensus Statement | Radiation protection for healthcare professionals working in catheterization laboratories during pregnancy.
9 Dec, 2022 | 13:26h | UTCCommentary: Expert Consensus Advocates for Normalizing Pregnancy in Cath Labs – TCTMD
Commentary on Twitter
A joint statement on radiation risk and the existing data on the experience of radiation-exposed cardiologists who continue to work in cath labs throughout their pregnancies. @SilbermanManzo @alaide_chief #EAPCI #CARDIOTWITTER https://t.co/UvCNN16klW pic.twitter.com/2kKR0KXf1X
— EuroIntervention (@EuroInterventio) November 22, 2022
Endocervical sampling in women with suspected cervical neoplasia: a meta-analysis of diagnostic test accuracy studies.
9 Dec, 2022 | 13:12h | UTC
Cohort Study | Comparative safety of antiseizure medication monotherapy in pregnancy for major malformations.
9 Dec, 2022 | 13:10h | UTCComparative safety of antiseizure medication monotherapy for major malformations – Annals of Neurology (link to abstract – $ for full-text)
Related:
Risks of 23 Specific Malformations Associated with Prenatal Exposure to 10 Antiepileptic Drugs
Research: Topiramate Use Early in Pregnancy and the Risk of Oral Clefts
Educational attainment of children born to mothers with epilepsy – Journal of Neurology, Neurosurgery, and Psychiatry (link to abstract – $ for full-text)
Cohort Study | Relationship between unremoved cervical polyp in pregnancy and spontaneous preterm birth.
9 Dec, 2022 | 13:05h | UTC
Commentary on Twitter
Relationship between unremoved cervical polyp in pregnancy and spontaneous preterm birth https://t.co/Z2bq81Xoqr pic.twitter.com/JXALaGxyFO
— AJOG (@AJOG_thegray) December 8, 2022
Cohort Study | Association of in utero antipsychotic medication exposure with risk of congenital malformations.
8 Dec, 2022 | 13:00h | UTCAssociation of In Utero Antipsychotic Medication Exposure With Risk of Congenital Malformations in Nordic Countries and the US – JAMA Psychiatry (free for a limited period)
Related:
Commentary on Twitter
New findings from a large cohort study including 26,000 antipsychotic-exposed pregnancies from 6 countries suggest that prenatal exposure to individual antipsychotics is generally not associated with an increase in risk of major congenital malformations https://t.co/4cUm8sXgsi
— JAMA Psychiatry (@JAMAPsych) December 7, 2022
RCT | Effect of Vitamin C for pregnant smokers on offspring airway function and wheeze at age 5 years.
8 Dec, 2022 | 12:47h | UTCEffect of Vitamin C Supplementation for Pregnant Smokers on Offspring Airway Function and Wheeze at Age 5 Years: Follow-up of a Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)
News Release: Researchers discover that vitamin C improves health for children of pregnant smokers – Oregon Health & Science University
Commentary on Twitter
This study found that offspring of pregnant smokers who were randomized to Vitamin C supplementation during pregnancy had increase airway function at age 5 years and decreased wheeze. https://t.co/yXSBzJlkIq #Research
— JAMA Pediatrics (@JAMAPediatrics) November 21, 2022
Retrospective Study | The incidence and predictability of high-risk conditions potentially warranting a higher level of maternal care.
8 Dec, 2022 | 12:37h | UTC
Commentary on Twitter
The incidence and predictability of high-risk conditions potentially warranting a higher level of maternal care https://t.co/bmFjp7YMdN pic.twitter.com/RJ9p6Tscyj
— AJOG (@AJOG_thegray) December 2, 2022
RCT | Effect of intraoperative Esketamine infusion on postoperative sleep disturbance after gynecological laparoscopy.
7 Dec, 2022 | 14:15h | UTC
Commentary on Twitter
RCT: intraaoperative esketamine infusion decreased the incidence of postoperative sleep disturbance in patients undergoing gynecological laparoscopic surgery. https://t.co/8qWiS6TtHA @xingmingwang006
— JAMA Network Open (@JAMANetworkOpen) December 1, 2022
RCT | Efficacy of postoperative oral cephalexin and metronidazole on SSI in obese women undergoing cesarean section.
7 Dec, 2022 | 14:13h | UTC
SR | Cervical pessary for preventing preterm birth in singleton pregnancies.
7 Dec, 2022 | 13:51h | UTCCervical pessary for preventing preterm birth in singleton pregnancies – Cochrane Library
M-A | Pregnancy outcomes after first-trimester treatment with artemisinin derivatives vs. non-artemisinin antimalarials.
6 Dec, 2022 | 14:02h | UTC
Commentary on Twitter (thread – click for more)
#Malaria in early pregnancy can have severe consequences.
Though an effective treatment, artemisinin-based combination therapies (ACTs) have not been recommended in the first trimester due to safety concerns.
A study presents updated evidence on safety: https://t.co/zBF7CAMRyY pic.twitter.com/2xRNvfTfx8
— The Lancet (@TheLancet) December 2, 2022
Monkeypox in pregnancy: virology, clinical presentation, and obstetric management.
6 Dec, 2022 | 13:58h | UTCRelated:
WHO renames “monkeypox” as “mpox” to help destigmatize the disease.
Study shows there is substantial monkeypox transmission before symptoms appear.
Monkeypox – New England Journal of Medicine
Monkeypox: disease epidemiology, host immunity and clinical interventions.
Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health
CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.
Update on the Monkeypox Outbreak – JAMA
WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch
Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases