Maternal-fetal Medicine | Page 8 of 22 | Links Medicus Content Curation & Alerts in Medicine

RCT | Effect of Vitamin C for pregnant smokers on offspring airway function and wheeze at age 5 years.

8 Dec, 2022 | 12:47h | UTC

Effect of Vitamin C Supplementation for Pregnant Smokers on Offspring Airway Function and Wheeze at Age 5 Years: Follow-up of a Randomized Clinical Trial – JAMA Pediatrics (link to abstract – $ for full-text)

News Release: Researchers discover that vitamin C improves health for children of pregnant smokers – Oregon Health & Science University

Commentary on Twitter

This study found that offspring of pregnant smokers who were randomized to Vitamin C supplementation during pregnancy had increase airway function at age 5 years and decreased wheeze. https://t.co/yXSBzJlkIq #Research

— JAMA Pediatrics (@JAMAPediatrics) November 21, 2022

Retrospective Study | The incidence and predictability of high-risk conditions potentially warranting a higher level of maternal care.

8 Dec, 2022 | 12:37h | UTC

The incidence and predictability of high-risk conditions potentially warranting a higher level of maternal care – American Journal of Obstetrics & Gynecology

Commentary on Twitter

https://twitter.com/AJOG_thegray/status/1598745297844305922

RCT | Efficacy of postoperative oral cephalexin and metronidazole on SSI in obese women undergoing cesarean section.

7 Dec, 2022 | 14:13h | UTC

Effectiveness of postoperative oral administration of cephalexin and metronidazole on surgical site infection among obese women undergoing cesarean section: a randomized, double-blind, placebo-controlled, parallel-group study-phase III – Antimicrobial Resistance & Infection Control

SR | Cervical pessary for preventing preterm birth in singleton pregnancies.

7 Dec, 2022 | 13:51h | UTC

Cervical pessary for preventing preterm birth in singleton pregnancies – Cochrane Library

Summary: Vaginal cervical support device to prevent delivery of a single baby before 37 weeks – Cochrane Library

M-A | Pregnancy outcomes after first-trimester treatment with artemisinin derivatives vs. non-artemisinin antimalarials.

6 Dec, 2022 | 14:02h | UTC

Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis – The Lancet

Commentary: Meta-analysis informed the updated WHO guidelines for treatment of uncomplicated malaria in the first trimester of pregnancy – Infectious Diseases Data Observatory (IDDO)

Commentary on Twitter (thread – click for more)

#Malaria in early pregnancy can have severe consequences.

Though an effective treatment, artemisinin-based combination therapies (ACTs) have not been recommended in the first trimester due to safety concerns.

A study presents updated evidence on safety: https://t.co/zBF7CAMRyY pic.twitter.com/2xRNvfTfx8

— The Lancet (@TheLancet) December 2, 2022

Monkeypox in pregnancy: virology, clinical presentation, and obstetric management.

6 Dec, 2022 | 13:58h | UTC

Monkeypox in pregnancy: virology, clinical presentation, and obstetric management – American Journal of Obstetrics & Gynecology

WHO renames “monkeypox” as “mpox” to help destigmatize the disease.

Monkeypox – The Lancet

Study shows there is substantial monkeypox transmission before symptoms appear.

Global monkeypox case hospitalisation rates: A rapid systematic review and meta-analysis – eClinicalMedicine

Human monkeypox virus infection in women and non-binary individuals during the 2022 outbreaks: a global case series – The Lancet

Monkeypox — A Sobering Sentinel for Pandemic Preparedness and Sexual Health System Capacity – New England Journal of Medicine

CDC study shows healthcare workers have a low risk of infection after exposure to patients with monkeypox.

Monkeypox – New England Journal of Medicine

Diagnosis and Management of Monkeypox: A Review for the Emergency Clinician – Annals of Emergency Medicine

Monkeypox: disease epidemiology, host immunity and clinical interventions.

Monkeypox: A clinical update for paediatricians – Journal of Pediatrics and Child Health

Cohort Study | Clinical presentation and virological assessment of confirmed human monkeypox virus cases in Spain.

CDC Report | Epidemiologic and clinical characteristics of Monkeypox cases in the US.

Update on the Monkeypox Outbreak – JAMA

Antivirals with Activity Against Monkeypox: A Clinically Oriented Review – Clinical Infectious Diseases

Clinical features and novel presentations of human monkeypox in a central London centre during the 2022 outbreak: descriptive case series – The BMJ

WHO Declares Global Public Health Emergency Over Monkeypox Virus Outbreak – Health Policy Watch

Monkeypox Virus Infection in Humans across 16 Countries — April–June 2022 – New England Journal of Medicine

Monkeypox: A Contemporary Review for Healthcare Professionals – Open Forum Infectious Diseases

Cohort Study | Obstetric and perinatal outcomes of singleton births following single- vs. double-embryo transfer.

6 Dec, 2022 | 13:45h | UTC

Obstetric and Perinatal Outcomes of Singleton Births Following Single- vs Double-Embryo Transfer in Sweden – JAMA Pediatrics

Commentary on Twitter

Swedish study comparing outcomes in singleton births following either single or double embryo transfer found higher risks of very preterm birth and low birth weight after double embryo transfer, especially when using frozen embryos and blastocysts. https://t.co/CXRXrchbw1

— JAMA Pediatrics (@JAMAPediatrics) December 5, 2022

Cohort Study | Buprenorphine may be a safer option than Methadone for opioid use disorder in pregnancy.

2 Dec, 2022 | 14:42h | UTC

Buprenorphine versus Methadone for Opioid Use Disorder in Pregnancy – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Buprenorphine, Not Methadone, May Be Safer Treatment for Opioid-Use Disorder During Pregnancy – Rutgers University

Perspective | Clinical trials and pregnancy.

2 Dec, 2022 | 14:25h | UTC

Clinical trials and pregnancy – Communications Medicine

The Moral Imperative to Include Pregnant Women in Clinical Trials of Interventions for COVID-19 – Annals of Internal Medicine

Excluding pregnancy from COVID-19 trials: Protection from harm or the harm of protection? – Canadian Medical Association Journal

Cohort Study | Impact of the trimester of diagnosis on COVID-19 disease progression in pregnancy.

29 Nov, 2022 | 14:18h | UTC

Examining the impact of trimester of diagnosis on COVID-19 disease progression in pregnancy – American Journal of Obstetrics & Gynecology MFM (free for a limited period)

News Release: Risk of severe COVID-19 symptoms remains throughout pregnancy, study finds – UT Southwestern Medical Center

Commentary on Twitter

Aug 20: Examining impact of trimester of diagnosis on #COVID19 disease progression in #pregnancy: Moderate, severe, or critical illness develops in almost 10% of pregnant patients; frequency of disease progression does not differ by trimester @ajogmfm https://t.co/hnF8QxmE2k!

— All Source Pregnancy (@PregnancyAll) August 20, 2022

Review | Infectious complications of abortion.

29 Nov, 2022 | 13:56h | UTC

Infectious Complications of Abortion – Open Forum Infectious Diseases

Review | The complex challenge of antenatal steroid therapy nonresponsiveness.

29 Nov, 2022 | 13:52h | UTC

The complex challenge of antenatal steroid therapy nonresponsiveness – American Journal of Obstetrics & Gynecology

M-A | Acupuncture for low back and/or pelvic pain during pregnancy.

23 Nov, 2022 | 13:52h | UTC

Acupuncture for low back and/or pelvic pain during pregnancy: a systematic review and meta-analysis of randomised controlled trials – BMJ Open

News Release: Acupuncture can relieve lower back/pelvic pain often experienced during pregnancy – BMJ Newsroom

Cohort Study | Association of pregnancy characteristics and maternal mortality with amniotic fluid embolism.

23 Nov, 2022 | 13:51h | UTC

Association of Pregnancy Characteristics and Maternal Mortality With Amniotic Fluid Embolism – JAMA Network Open

Invited Commentary: Toward Risk Assessment for Amniotic Fluid Embolisms – JAMA Network Open

Commentary on Twitter

https://twitter.com/JAMANetworkOpen/status/1593710640056897536

M-A | Balloon catheters vs. vaginal prostaglandins for labor induction.

22 Nov, 2022 | 13:35h | UTC

Balloon catheters versus vaginal prostaglandins for labour induction (CPI Collaborative): an individual participant data meta-analysis of randomised controlled trials – The Lancet (link to abstract – $ for full-text)

Commentary: Balloon labor induction safer for babies, researchers find – Monash University

Commentary on Twitter (thread – click for more)

https://twitter.com/TheLancet/status/1592460860026679296

Cohort Study | Association of antidepressant use during pregnancy with risk of neurodevelopmental disorders in children.

21 Nov, 2022 | 14:33h | UTC

Association of Antidepressant Use During Pregnancy With Risk of Neurodevelopmental Disorders in Children – JAMA Internal Medicine (link to abstract – $ for full-text)

Commentaries:

Antidepressant Use During Pregnancy Not Associated With Neurodevelopmental Risk in Children – Psychiatric News Alert

Antidepressants in Pregnancy Do Not Affect Child Neurodevelopment – HealthDay

Commentary on Twitter

https://twitter.com/JAMAInternalMed/status/1593046260440776704

M-A | Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders.

21 Nov, 2022 | 14:11h | UTC

Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders: An umbrella review of randomised controlled trials and an updated meta-analysis – BJOG

Commentary on Twitter

https://twitter.com/BJOGTweets/status/1578676322095742977

Retrospective Cohort Study | Perinatal outcomes associated with ICP in twin pregnancies were worse than singletons.

11 Nov, 2022 | 13:36h | UTC

Perinatal outcomes associated with ICP in twin pregnancies were worse than singletons: an almost 5-year retrospective cohort study – BMC Pregnancy and Childbirth

RCT | Intermediate-dose no better than low-dose LMWH in pregnant and post-partum women with previous thromboembolism.

10 Nov, 2022 | 14:12h | UTC

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial – The Lancet (link to abstract – $ for full-text)

Commentary from the author on Twitter (thread – click for more)

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial https://t.co/9zHeUIda7o

— Saskia Middeldorp (@MiddeldorpS) October 28, 2022

RCT | Monofilament suture is no better than braided suture to improve pregnancy outcomes after vaginal cervical cerclage.

10 Nov, 2022 | 14:14h | UTC

Monofilament suture versus braided suture thread to improve pregnancy outcomes after vaginal cervical cerclage (C-STICH): a pragmatic randomised, controlled, phase 3, superiority trial – The Lancet

Invited Commentary: Suture choice for cervical cerclage – The Lancet (free registration required)

News Release: Single stranded suture threads could prevent pregnancy infection complications, C-STICH trial finds – University of Birmingham

Video Summary: Major trial finds purse-string wire in surgery can reduce miscarriage and stillbirth – University of Birmingham

Commentary: Monofilament Suture Not Superior for Vaginal Cervical Cerclage – HealthDay

Commentary on Twitter (thread – click for more)

Vaginal cervical cerclage is performed to prevent pregnancy loss and preterm birth.

In this trial, researchers assessed the effect on pregnancy loss of using a monofilament suture thread compared with braided suture thread: https://t.co/kBgGGn5D4L

— The Lancet (@TheLancet) October 27, 2022

Study | In hypertensive disorders of pregnancy, the levels of angiogenic factors may stratify the risk of severe preeclampsia.

10 Nov, 2022 | 14:11h | UTC

Circulating Angiogenic Factor Levels in Hypertensive Disorders of Pregnancy – NEJM Evidence

Commentary on Twitter

This study measured the ratio of serum soluble fms-like tyrosine kinase (sFlt-1) to placental growth factor (PIGF) in pregnant pts hospitalized with HTN. An sFLT-1:PIGF ratio ≥ 40 stratified the risk of progressing to severe pre-eclampsia within 2 wks. https://t.co/H0uSHT2bN7 pic.twitter.com/ZKRvHsqLA4

— NEJM Evidence (@NEJMEvidence) November 9, 2022