M-A | Pregnancy outcomes after first-trimester treatment with artemisinin derivatives vs. non-artemisinin antimalarials.

Pregnancy outcomes after first-trimester treatment with artemisinin derivatives versus non-artemisinin antimalarials: a systematic review and individual patient data meta-analysis – The Lancet

Commentary: Meta-analysis informed the updated WHO guidelines for treatment of uncomplicated malaria in the first trimester of pregnancy – Infectious Diseases Data Observatory (IDDO)

Commentary on Twitter (thread – click for more)

#Malaria in early pregnancy can have severe consequences.

Though an effective treatment, artemisinin-based combination therapies (ACTs) have not been recommended in the first trimester due to safety concerns.

A study presents updated evidence on safety: https://t.co/zBF7CAMRyY pic.twitter.com/2xRNvfTfx8

— The Lancet (@TheLancet) December 2, 2022