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Maternal-fetal Medicine

SR | The effect of parental leave on parents’ mental health

15 Feb, 2023 | 15:44h | UTC

The effect of parental leave on parents’ mental health: a systematic review – The Lancet Public Health

Invited Commentary: Paid parental leave and mental health: the importance of equitable policy design – The Lancet Public Health

News Release: Generous parental leave schemes protect against poorer mental health – Stockholm University / News Medical

 


Cohort Study | In utero exposure to ADHD medication does not seem to result in worse offspring neurodevelopmental outcomes

14 Feb, 2023 | 10:54h | UTC

Summary: The authors conducted a study to investigate the long-term effects of in utero exposure to ADHD medication (methylphenidate, amphetamine, dexamphetamine, lisdexamphetamine, modafinil, atomoxetine, clonidine) on offspring. The study followed 1,068,073 liveborn singletons from 1998 to 2018 and compared the outcomes of children whose mothers continued or discontinued ADHD medication during pregnancy. The main outcomes were neurodevelopmental psychiatric disorders, impairments in vision or hearing, epilepsy, seizures, or growth impairment during childhood or adolescence. After adjustment for demographic and psychiatric characteristics of the mother, no increased risk of any developmental disorders was found in offspring exposed to ADHD medication compared to those not exposed. The results provide reassurance for women with ADHD who depend on medication and consider continuing it during pregnancy.

(By ChatGPT, reviewed and edited)

 

Article: In utero exposure to ADHD medication and long-term offspring outcomes – Molecular Psychiatry (link to abstract – $ for full-text)

News Release: Study: Pregnant women on ADHD medications shouldn’t worry about pediatric neurodevelopmental disorders – The Mount Sinai Hospital

 

Commentary from the author on Twitter (thread – click for more)

 


Stillbirth after adolescent and young adult cancer: a population-based study

14 Feb, 2023 | 10:33h | UTC

Stillbirth After Adolescent and Young Adult Cancer: A Population-Based Study – JNCI: Journal of the National Cancer Institute

News Release: Cancer in adolescent and young adult women before pregnancy does not increase risk for stillborn births, according to UTHealth Houston research

Commentary: Previous Cancer Treatment Not Tied to Higher Stillbirth Rate – HealthDay

 


RCT | Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy

14 Feb, 2023 | 10:31h | UTC

Testing equivalence of two doses of intravenous iron to treat iron deficiency in pregnancy: A randomised controlled trial – BJOG

 


Development of a machine learning model for sonographic assessment of gestational age

14 Feb, 2023 | 10:30h | UTC

Development of a Machine Learning Model for Sonographic Assessment of Gestational Age – JAMA Network Open

Commentary: AI Models Have Higher Accuracy for Estimating Gestational Age – HealthDay

 


RCT | Azithromycin reduces the risk of maternal sepsis or death in women planning a vaginal birth

13 Feb, 2023 | 13:02h | UTC

Azithromycin to Prevent Sepsis or Death in Women Planning a Vaginal Birth – New England Journal of Medicine (link to abstract – $ for full-text)

News Release: Single-dose antibiotic prevents maternal sepsis and death – NIH News

Commentaries:

In large study, a single antibiotic dose slashed rate of sepsis in childbirth – STAT

Dose of azithromycin found to cut risk of maternal death, sepsis in childbirth – CIDRAP

Single dose of the antibiotic azithromycin decreases sepsis and death risk during childbirth – News Medical/ University of Virginia Health System

 


The Lancet Series | Breastfeeding 2023

13 Feb, 2023 | 12:52h | UTC

Homepage: Breastfeeding 2023 – The Lancet

Editorial: Unveiling the predatory tactics of the formula milk industry

Breastfeeding: crucially important, but increasingly challenged in a market-driven world

Marketing of commercial milk formula: a system to capture parents, communities, science, and policy

The political economy of infant and young child feeding: confronting corporate power, overcoming structural barriers, and accelerating progress

Stemming commercial milk formula marketing: now is the time for radical transformation to build resilience for breastfeeding

Commentaries:

Expert reaction to review of formula baby milk – Science Media Centre

Lancet Series outlines baby formula companies’ exploitative marketing playbook to sell products – University of the Witwatersrand/News Medical

 


US infant pertussis incidence trends before and after implementation of the maternal Tdap vaccine

13 Feb, 2023 | 12:38h | UTC

US Infant Pertussis Incidence Trends Before and After Implementation of the Maternal Tetanus, Diphtheria, and Pertussis Vaccine – JAMA Pediatrics (free for a limited period)

Commentary: Maternal Tdap Vaccination Protects Youngest Infants From Pertussis – HealthDay

 

Commentary on Twitter

 


POTS and Pregnancy: a review of literature and recommendations for evaluation and treatment

10 Feb, 2023 | 13:37h | UTC

POTS and Pregnancy: A Review of Literature and Recommendations for Evaluation and Treatment – International Journal of Women’s Health

 


Cohort Study | Adverse pregnancy outcomes and long-term risk of ischemic heart disease in mothers

9 Feb, 2023 | 14:02h | UTC

Adverse pregnancy outcomes and long term risk of ischemic heart disease in mothers: national cohort and co-sibling study – The BMJ

News Release: Five major adverse pregnancy outcomes associated with long term risks of ischemic heart disease – News Medical/BMJ

Commentary: Complications during pregnancy linked to a higher risk of heart disease, study finds – CNN

Related:

Risk and trajectory of premature ischemic CVD in women with a history of pre-eclampsia: a nationwide register-based study

Cohort Study | Pre-eclampsia is associated with increased risk of premature-onset obstructive coronary artery stenosis.

Primary Care–Based Cardiovascular Disease Risk Management After Adverse Pregnancy Outcomes: a Narrative Review – Journal of General Internal Medicine

Pregnancy Complications and Risk of Cardiovascular Disease Later in Life: A Nationwide Cohort Study – Journal of the American Heart Association

AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk

Consensus statement: Cardiovascular health after menopause transition, pregnancy disorders, and other gynecologic conditions

Cohort Study: Preeclampsia and Cardiovascular Disease

Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors

All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease

Gestational Hypertension and Future Risk of Cardiovascular Disease

Research: Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents

 


RCT | Pregnancy and neonatal safety of PrEP for HIV prevention initiated during pregnancy vs. afterwards

9 Feb, 2023 | 13:55h | UTC

Pregnancy and neonatal safety outcomes of timing of initiation of daily oral tenofovir disoproxil fumarate and emtricitabine pre-exposure prophylaxis for HIV prevention (CAP016): an open-label, randomised, non-inferiority trial – The Lancet HIV (link to abstract – $ for full-text)

 


Guideline | Fetal monitoring in labor

9 Feb, 2023 | 13:48h | UTC

Fetal monitoring in labour – National Institute for Health and Care Excellence

 


Guideline | Intrapartum care for healthy women and babies

9 Feb, 2023 | 13:49h | UTC

Intrapartum care for healthy women and babies – National Institute for Health and Care Excellence

 


Review | The role of MRI in the diagnosis and prognostic evaluation of fetuses with congenital diaphragmatic hernia

9 Feb, 2023 | 13:40h | UTC

The role of magnetic resonance imaging in the diagnosis and prognostic evaluation of fetuses with congenital diaphragmatic hernia – European Journal of Pediatrics

 


RCT | Outcomes in children of women with type 2 diabetes exposed to metformin vs. placebo during pregnancy

8 Feb, 2023 | 12:32h | UTC

Outcomes in children of women with type 2 diabetes exposed to metformin versus placebo during pregnancy (MiTy Kids): a 24-month follow-up of the MiTy randomised controlled trial – The Lancet Diabetes & Endocrinology (link to abstract – $ for full-text)

 


M-A | Comparative effectiveness of prophylactic strategies for preeclampsia

2 Feb, 2023 | 14:42h | UTC

Comparative effectiveness of prophylactic strategies for preeclampsia: a network meta-analysis of randomized controlled trials – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Commentary: Meta‐analysis reveals effective prophylactic strategies for preeclampsia – MDEdge

 


M-A | Effects of opioids administered via intravenous or epidural patient-controlled analgesia after cesarean section

1 Feb, 2023 | 12:55h | UTC

Effects of opioids administered via intravenous or epidural patient-controlled analgesia after caesarean section: A network meta-analysis of randomised controlled trials – eClinicalMedicine

 


Review | Exercise during pregnancy: effects on birth weight and on the risks of gestational diabetes and preterm delivery

31 Jan, 2023 | 13:45h | UTC

Exercise During Pregnancy: Effects on Birth Weight and on the Risks of Gestational Diabetes and Preterm Delivery – Deutsches Ärzteblatt international

Related:

Exercise during pregnancy for preventing gestational diabetes mellitus and hypertensive disorders: An umbrella review of randomised controlled trials and an updated meta-analysis – BJOG

Effectiveness of exercise intervention during pregnancy on high-risk women for gestational diabetes mellitus prevention: A meta-analysis of published RCTs – PLOS One

Effect of diet and physical activity based interventions in pregnancy on gestational weight gain and pregnancy outcomes

 


Report | Tranexamic acid at cesarean delivery: drug-error deaths

31 Jan, 2023 | 13:39h | UTC

Tranexamic acid at cesarean delivery: drug-error deaths – American Journal of Obstetrics & Gynecology

Related: RCT: Tranexamic acid for the prevention of blood loss after cesarean delivery – even though TA resulted in a significantly lower incidence of estimated blood loss, the clinical relevance of the findings was small

 


Risk and trajectory of premature ischemic CVD in women with a history of pre-eclampsia: a nationwide register-based study

30 Jan, 2023 | 01:08h | UTC

Risk and trajectory of premature ischaemic cardiovascular disease in women with a history of pre-eclampsia: a nationwide register-based study – European Journal of Preventive Cardiology (free for a limited period)

News Release: Pre-eclampsia linked with four-fold higher risk of heart attack in decade after delivery – European Society of Cardiology

Commentaries:

Preeclampsia Increases Heart Attack, Stroke Risk for Up to 20 Years After Pregnancy – HCP Live

Preeclampsia in Pregnancy a Bad Sign for Women’s Future Heart Health – HealthDay

Related:

Cohort Study | Pre-eclampsia is associated with increased risk of premature-onset obstructive coronary artery stenosis.

Primary Care–Based Cardiovascular Disease Risk Management After Adverse Pregnancy Outcomes: a Narrative Review – Journal of General Internal Medicine

Pregnancy Complications and Risk of Cardiovascular Disease Later in Life: A Nationwide Cohort Study – Journal of the American Heart Association

AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk

Consensus statement: Cardiovascular health after menopause transition, pregnancy disorders, and other gynecologic conditions

Cohort Study: Preeclampsia and Cardiovascular Disease

Cohort Study: Cardiovascular Disease After Hypertensive Disorders of Pregnancy Largely Explained by Conventional Cardiovascular Risk Factors

All Hypertensive Disorders of Pregnancy Increase the Risk of Future Cardiovascular Disease

Gestational Hypertension and Future Risk of Cardiovascular Disease

Research: Conjoint Associations of Gestational Diabetes and Hypertension With Diabetes, Hypertension, and Cardiovascular Disease in Parents

 


RCT | Effect of second-stage pushing timing on postpartum pelvic floor morbidity

30 Jan, 2023 | 00:31h | UTC

Effect of Second-Stage Pushing Timing on Postpartum Pelvic Floor Morbidity: A Randomized Controlled Trial – Obstetrics & Gynecology (free for a limited period)

 

Commentary on Twitter

 


European guidelines on perinatal care: corticosteroids for women at risk of preterm birth

25 Jan, 2023 | 11:32h | UTC

European guidelines on perinatal care: corticosteroids for women at risk of preterm birth – The Journal of Maternal-Fetal & Neonatal Medicine

 


RCT | Routine use of endometrial receptivity testing to guide the timing of frozen embryo transfer did not improve the rates of live birth

20 Jan, 2023 | 14:45h | UTC

Effect of Timing by Endometrial Receptivity Testing vs Standard Timing of Frozen Embryo Transfer on Live Birth in Patients Undergoing In Vitro Fertilization: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)

 

Commentary on Twitter

 


Gestational age at birth and cognitive outcomes in adolescence: population based full sibling cohort study

19 Jan, 2023 | 14:27h | UTC

Gestational age at birth and cognitive outcomes in adolescence: population based full sibling cohort study – The BMJ

Editorial: Gestational age at birth and school performance – The BMJ

News Release: Premature birth linked to poorer school grades in adolescence – BMJ

 


Review | An FP’s guide to identifying—and treating—postpartum depression

19 Jan, 2023 | 13:56h | UTC

An FP’s guide to identifying—and treating—postpartum depression – Journal of Family Practice

 


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