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Cohort Study | Association of large-for-gestational age birth and prediabetes/diabetes 10-14 years’ postpartum

24 Feb, 2023 | 13:43h | UTC

Summary: Several studies show that women who develop diabetes during pregnancy are at increased risk of developing diabetes later in life. This study investigated whether giving birth to a larger-than-normal baby is associated with an increased risk of prediabetes or diabetes 10-14 years after pregnancy in individuals without gestational diabetes. The study used data from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Follow-up Study, including pregnant individuals without gestational diabetes. After adjusting for various baseline maternal characteristics, the researchers found that individuals who gave birth to a large-for-gestational age (LGA) infant had a 21% higher risk of being diagnosed with prediabetes or diabetes 10-14 years after delivery compared to those who had an appropriate-for-gestational age (AGA) infant. The study concluded that having a previous LGA infant is a marker of increased risk of developing prediabetes or diabetes in individuals without gestational diabetes.

Abstract: Association of large-for-gestational age birth and prediabetes/diabetes 10-14 years’ postpartum in the HAPO follow-up study – American Journal of Obstetrics & Gynecology (link to abstract, presented at the Society for Maternal-Fetal Medicine’s annual meeting)

News Release: New study reveals pregnant people who deliver large babies are at increased risk of developing diabetes later in life – Society for Maternal-Fetal Medicine

Commentaries:

Delivering a Plus-Sized Baby Could Be Sign of Diabetes Risk – HealthDay

Large for Gestational Age Births Could Increase Diabetes Risk in Women – HCP Live

 


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