Maternal-fetal Medicine
RCT: Among pregnant women with primary CMV infection diagnosed before 24 weeks’ gestation, monthly infusion of CMV hyperimmune globulin did not prevent congenital cytomegalovirus infection.
30 Jul, 2021 | 11:42h | UTCA Trial of Hyperimmune Globulin to Prevent Congenital Cytomegalovirus Infection – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Hyperimmune Globulin Fails to Prevent Congenital CMV – Physician’s Weekly
SARS-COV-2 infection during pregnancy and risk of preeclampsia: a systematic review and meta-analysis.
28 Jul, 2021 | 10:13h | UTC
The use and impact of monoclonal antibody biologics during pregnancy.
28 Jul, 2021 | 09:43h | UTC
M-A: Low-molecular-weight heparin for prevention of preeclampsia and other placenta-mediated complications.
26 Jul, 2021 | 02:24h | UTC
Expert review | Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy.
21 Jul, 2021 | 10:37h | UTC
Commentary on Twitter
AJOG Expert Review in Preeclampsia: Postpartum preeclampsia or eclampsia: defining its place and management among the hypertensive disorders of pregnancy https://t.co/xdZbn51ymU pic.twitter.com/N90GdbdBBw
— AJOG (@AJOG_thegray) July 20, 2021
Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.
14 Jul, 2021 | 11:20h | UTCBetween BNT162b2 Vaccination and Incidence of SARS-CoV-2 Infection in Pregnant Women – JAMA
Commentary: Pfizer COVID vaccine shows 78% efficacy in pregnancy – CIDRAP
Top 10 pearls for the recognition, evaluation, and management of maternal sepsis.
13 Jul, 2021 | 09:25h | UTC
RCOG Guidance: Coronavirus (COVID-19) Vaccination in Pregnancy.
7 Jul, 2021 | 08:53h | UTCCoronavirus (COVID-19) Vaccination in Pregnancy – Royal College of Obstetricians & Gynaecologists
See also: Resources and FAQs – Royal College of Obstetricians & Gynaecologists
Commentary on Twitter
We have published an interim update to the main coronavirus and pregnancy guidance to summarise the guidance on COVID-19 vaccination and pregnancy. Find out more: https://t.co/2YDyZFrVWJ pic.twitter.com/KnwXDvZls2
— RoyalCollegeObsGyn (@RCObsGyn) July 1, 2021
Pregnancy in congenital heart disease: risk prediction and counseling.
6 Jul, 2021 | 09:57h | UTCPregnancy in congenital heart disease: risk prediction and counselling – Heart
Commentary on Twitter
Pregnancy in congenital heart disease: risk prediction and counselling | Heart https://t.co/Vu77sKeqQV pic.twitter.com/1zvdEACHVR
— Heart_BMJ (@Heart_BMJ) December 19, 2020
M-A: Pregnancy After Breast Cancer – “These results provide reassuring evidence on the safety of conceiving in BC survivors”.
6 Jul, 2021 | 09:55h | UTCPregnancy After Breast Cancer: A Systematic Review and Meta-Analysis – Journal of Clinical Oncology (link to abstract – $ for full-text)
Commentary on Twitter
Honored and excited to share our large #metanalysis presented at #SABCS20 now published in @ASCO_pubs #JCO providing solid and reassuring evidence on fetal and maternal safety of #pregnancy after prior #BreastCancer history@OncoAlert #SurvOnc #bcsm
Link: https://t.co/lgKQDeB2VS pic.twitter.com/rTpFKsrpMc— Matteo Lambertini, MD PhD (@matteolambe) July 1, 2021
RCT showed improved outcomes with fetal surgery for severe left diaphragmatic hernia.
5 Jul, 2021 | 01:53h | UTCRandomized Trial of Fetal Surgery for Severe Left Diaphragmatic Hernia – New England Journal of Medicine (link to abstract – $ for full-text – Full text can be found here)
Commentary: Fetal Surgery Boosts Survival for Babies With Severe Birth Defect – MedPage Today (free registration required)
RCT: Prophylactic manual rotation of occiput posterior and transverse positions was associated with a reduced risk of operative delivery.
5 Jul, 2021 | 01:28h | UTCProphylactic manual rotation of occiput posterior and transverse positions to decrease operative delivery: the PROPOP randomized clinical trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Widespread implementation of a low-cost telehealth service in the delivery of antenatal care during the COVID-19 pandemic enabled the reduction of in-person consultations by 50% without compromising pregnancy outcomes.
2 Jul, 2021 | 11:26h | UTCCommentary: Expanding the concept of safety in antenatal care provision – The Lancet
Systematic review: low‐dose oral misoprostol probably has many benefits over other methods for labor induction.
24 Jun, 2021 | 09:44h | UTCLow‐dose oral misoprostol for induction of labour – Cochrane Library
WHO: Caesarean section rates continue to rise, amid growing inequalities in access.
18 Jun, 2021 | 08:23h | UTCOriginal study: Trends and projections of caesarean section rates: global and regional estimates – BMJ Global Health
Commentary on Twitter (thread – click for more)
Caesarean section use continues to rise 📈 globally, now accounting for more than 1 in 5 of all childbirths.
C-section can put women and babies at unnecessary risk of short- and long-term health problems if performed when there is not medical need
— World Health Organization (WHO) (@WHO) June 17, 2021
No health issues in babies whose moms got flu vaccine while pregnant.
9 Jun, 2021 | 08:17h | UTCNo health issues in babies whose moms got flu vaccine while pregnant – CIDRAP
Original study: Association of Maternal Influenza Vaccination During Pregnancy With Early Childhood Health Outcomes – JAMA (free for a limited period)
Editorial: Realizing the Potential of Maternal Influenza Vaccination (free for a limited period)
Commentary on Twitter
https://twitter.com/ericbenchimol/status/1402307635240706048
RCT: Vaginal administration of misoprostol is superior to buccal administration of misoprostol along with a Foley catheter for induction of labor.
9 Jun, 2021 | 08:11h | UTCBuccal vs vaginal misoprostol combined with Foley catheter for cervical ripening at term (the BEGIN trial): a randomized controlled trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary on Twitter
https://twitter.com/AJOG_thegray/status/1393529144395374592
Challenges and solutions for physician mothers: a critical review of the literature.
6 Jun, 2021 | 23:46h | UTC
Commentary on Twitter
Challenges and Solutions for Physician Mothers: A Critical Review of the Literature in @MayoProceedings
By @sherry_chesak @anjalibhagramd et al.#WomenInMedicine @AMWADoctors https://t.co/RXvXt739PN pic.twitter.com/7aNuA9JVJQ— Mayo Clinic GRIT (@MayoGRIT) April 9, 2021
USPSTF Statement: Clinicians should offer behavioral counseling interventions to promote healthy weight gain and prevent excess gestational weight gain in pregnancy.
1 Jun, 2021 | 08:08h | UTCEvidence Report: Counseling and Behavioral Interventions for Healthy Weight and Weight Gain in Pregnancy – JAMA
Author Interview: USPSTF Recommendation: Behavioral Counseling Interventions for Healthy Weight and Weight Gain in Pregnancy – JAMA
JAMA Patient Page: Behavioral Interventions for Healthy Weight Gain During Pregnancy
NICE recommends offering women induced labor earlier in new draft guidance – “women with uncomplicated singleton pregnancies should be offered induction at 41 weeks and the induction should take place as soon as possible. Previous guidelines advised induction between 41 and 42 weeks”.
31 May, 2021 | 08:08h | UTC
RCT: Immediate “kangaroo mother care” improves survival in infants with low birth weight compared to conventional care with “kangaroo mother care” initiated after stabilization.
27 May, 2021 | 08:18h | UTCCommentary: Immediate skin-to-skin contact after birth improves survival of pre-term babies – Karolisnka Institutet
Related: RCT: Community-initiated kangaroo mother care reduced the risk of moderate-to-severe maternal postpartum depressive symptoms among mothers of low-birth-weight infants in low-income areas in India AND WHO: New research highlights risks of separating newborns from mothers during COVID-19 pandemic AND Randomized Trial: Kangaroo Mother Care Improves Survival of Infants with Low Birthweight
RCT: Manual rotation of occiput posterior fetal positions at the start of the second stage of labor does not increase the rate of vaginal delivery without instrumental assistance.
26 May, 2021 | 08:17h | UTC
Risk factors for illness severity among pregnant women with confirmed SARS-CoV-2 infection – moderate-to-severe COVID-19 was associated with age 25 years and older, healthcare occupation, pre-pregnancy obesity, chronic lung disease, chronic hypertension, and pregestational diabetes mellitus.
24 May, 2021 | 08:34h | UTC
M-A: Compared to cefazolin alone, pre-incision cefazolin + adjunctive prophylaxis with macrolides or metronidazole significantly reduces the incidence of post-cesarean surgical site infection and hospital stay.
20 May, 2021 | 08:19h | UTCPre-incision Adjunctive Prophylaxis for Cesarean Sections: A Systematic Review and Meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
RCT: Prophylactic closed incision negative pressure wound therapy reduces (difference close to statistical significance; P=0.06) the risk of surgical site infection in obese women undergoing cesarean section.
7 May, 2021 | 08:24h | UTC