Maternal-fetal Medicine | Page 20 of 21 | Links Medicus Content Curation & Alerts in Medicine

RCT: Metformin vs. insulin in gestational diabetes – metformin was associated better glycemic control, lower risk of hypoglycemia, and less maternal weight gain

25 Apr, 2021 | 21:03h | UTC

MeDiGes Study. Metformin versus insulin in gestational diabetes: Glycemic control, and obstetrical and perinatal outcomes. Randomized prospective trial. – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

RCT: Induction of Labor at Term with Vaginal Misoprostol or a PGE2 Pessary – little difference in outcomes, the clinical risk-benefit ratio justifies the use of both drugs

25 Apr, 2021 | 20:59h | UTC

Induction of Labor at Term With Vaginal Misoprostol or a PGE2 Pessary: a Noninferiority RCT – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

Recommendations on the Management of Maternal Hepatitis B, C and D Infection in Pregnancy

25 Apr, 2021 | 20:44h | UTC

Recommendations of the AGG (Task Force for Obstetrics, Section Maternal Diseases) on the Management of Maternal Hepatitis B, C and D Infection in Pregnancy – Geburtshilfe und Frauenheilkunde

Covid-19: More data on the increased risks to pregnant women and their newborn infants

23 Apr, 2021 | 08:44h | UTC

Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection: The INTERCOVID Multinational Cohort Study – JAMA Pediatrics

Editorial: COVID-19 in Pregnant Women and Their Newborn Infants

Commentaries: Pregnant women with COVID-19 face high mortality rate – University of Washington School of Medicine AND Covid-19 raises risks for expectant mothers and babies, study says – CNN

Commentary on Twitter

18 country study in >2000 pregnant women with and without #COVID19 shows higher complication and death rates in symptomatic, but not asymptomatic, women with COVID-19. Their babies were at greater risk of neonatal complications, mainly due to preterm birth https://t.co/mRl8OOIMsz

— JAMA Pediatrics (@JAMAPediatrics) April 22, 2021

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons

22 Apr, 2021 | 08:49h | UTC

Preliminary Findings of mRNA Covid-19 Vaccine Safety in Pregnant Persons – New England Journal of Medicine

Audio Interview: Covid-19 Vaccines and Pregnancy — A Conversation with CDC Director Rochelle Walensky – New England Journal of Medicine

Commentaries: No evidence that Pfizer or Moderna vaccines are unsafe during pregnancy, a preliminary study says. – The New York Times AND Preliminary data show no safety concerns for pregnant women receiving COVID-19 vaccines – AAP News AND Messenger RNA COVID vaccines likely safe for pregnant women: Study – ABC News

Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions

22 Apr, 2021 | 08:19h | UTC

Maternal, Fetal, and Child Outcomes of Mental Health Treatments in Women: A Systematic Review of Perinatal Pharmacologic Interventions – Agency for Healthcare Research and Quality

See also: Final Report AND Evidence Summary

M-A: Progestogens for preventing miscarriage

21 Apr, 2021 | 06:22h | UTC

Progestogens for preventing miscarriage: a network meta‐analysis – Cochrane Library

Summary: Are progestogen treatments effective in preventing miscarriage? – Cochrane Library

RCT: Continued versus discontinued oxytocin stimulation in the active phase of labor

16 Apr, 2021 | 06:18h | UTC

Continued versus discontinued oxytocin stimulation in the active phase of labour (CONDISOX): double blind randomised controlled trial – The BMJ

Commentaries: Study sheds more light on use of oxytocin during labour – The BMJ AND Study Explores Oxytocin Use in Active Phase of Induced Labor – HealthDay

Commentary on Twitter

#BMJInfographic #VisualAbstract Routine discontinuation of oxytocin stimulation in the active phase of labour may lead to a small increase in caesarean section rate but a reduced risk of uterine hyperstimulation and abnormal fetal heart rate patterns https://t.co/LbCxUf1MSx pic.twitter.com/BSQ5rrwQb5

— The BMJ (@bmj_latest) April 15, 2021

Were pregnant women more affected by COVID-19 in the second wave of the pandemic?

16 Apr, 2021 | 06:24h | UTC

Were pregnant women more affected by COVID-19 in the second wave of the pandemic? – The Lancet

M-A: Antenatal corticosteroids for impending late preterm (34-36+6 weeks) deliveries

7 Apr, 2021 | 01:22h | UTC

Antenatal corticosteroids for impending late preterm (34-36+6 weeks) deliveries—A systematic review and meta-analysis of RCTs – PLOS One

Guideline for elective cesarean section: updated systematic review and procedure‐specific postoperative pain management recommendations

2 Apr, 2021 | 09:09h | UTC

PROSPECT guideline for elective caesarean section: updated systematic review and procedure‐specific postoperative pain management recommendations – Anaesthesia

Randomized controlled trial compared three antiretroviral regimens started in pregnant women with HIV

2 Apr, 2021 | 09:15h | UTC

Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2010/VESTED): a multicentre, open-label, randomised, controlled, phase 3 trial – The Lancet (link to abstract – $ for full-text)

Commentary: ART in pregnant women living with HIV – The Lancet

Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis

2 Apr, 2021 | 09:23h | UTC

Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis – The Lancet Global Health

Commentaries: Covid-19 led to a global increase in stillbirths, maternal mortality, and depression, review finds – CNN AND COVID-19 pandemic and health-care disruptions: count the most vulnerable – The Lancet Global Health

Commentary on Twitter

NEW—Pregnancy outcomes worsened during the #COVID19 pandemic worldwide, with an increase in maternal deaths, stillbirth, ruptured ectopic pregnancies, and maternal depression.

New review of 40 studies from 17 countries in @LancetGH: https://t.co/GWBohu6b6k pic.twitter.com/4RzgtShYeH

— The Lancet (@TheLancet) April 1, 2021

Obesity in women: anesthetic implications for peri‐operative and peripartum management

2 Apr, 2021 | 09:07h | UTC

Obesity in women: anaesthetic implications for peri‐operative and peripartum management – Anaesthesia

Cohort study: Association of spontaneous abortion with all cause and cause specific premature mortality

1 Apr, 2021 | 03:27h | UTC

Association of spontaneous abortion with all cause and cause specific premature mortality: prospective cohort study – The BMJ

Commentaries: Miscarriage linked to increased risk of early death – The BMJ AND Miscarriage Linked to Higher Risk for Premature Mortality – HealthDay

Commentary on Twitter

Study suggests spontaneous abortion is associated with a greater risk of premature death, particularly from cardiovascular disease. Spontaneous abortion could be an early marker of future health risk in women, including premature death, say the authorshttps://t.co/mA7IrF0J00

— The BMJ (@bmj_latest) March 28, 2021

RCT: Six vs. Twelve Hours of Single Balloon Catheter Placement with Oxytocin Administration for Labor Induction

31 Mar, 2021 | 03:02h | UTC

Six vs. Twelve Hours of Single Balloon Catheter Placement with Oxytocin Administration for Labor Induction: A Randomized Controlled Trial – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis

31 Mar, 2021 | 03:27h | UTC

The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis – Canadian Medical Association Journal

AHA Scientific Statement | Adverse Pregnancy Outcomes and Cardiovascular Disease Risk

30 Mar, 2021 | 03:08h | UTC

Adverse Pregnancy Outcomes and Cardiovascular Disease Risk: Unique Opportunities for Cardiovascular Disease Prevention in Women: A Scientific Statement From the American Heart Association – Circulation

News Release: Six pregnancy complications are among red flags for heart disease later in life – American Heart Association

M-A: Evaluating Progestogens for Preventing Preterm Birth

30 Mar, 2021 | 03:02h | UTC

Evaluating Progestogens for Preventing Preterm birth International Collaborative (EPPPIC): meta-analysis of individual participant data from randomised controlled trials – The Lancet (link to abstract – $ for full-text)

Cohort study: Even small amounts of Caffeine consumption in pregnancy were linked to smaller neonatal birth size

28 Mar, 2021 | 22:14h | UTC

Association Between Maternal Caffeine Consumption and Metabolism and Neonatal Anthropometry: A Secondary Analysis of the NICHD Fetal Growth Studies–Singletons – JAMA Network Open

Commentaries: Even a Little Coffee in Pregnancy Could Impact Newborn’s Weight: Study – HealthDay AND Moderate daily caffeine intake during pregnancy may lead to smaller birth size – NIH News Releases

Commentary on Twitter

Cohort study finds even small amounts of caffeine consumption in pregnancy were associated with smaller birthweight and lean tissue measures, consistent for measured plasma caffeine/paraxanthine, and self-reported caffeine consumption. @NIH https://t.co/YzDVU6ejYO

— JAMA Network Open (@JAMANetworkOpen) March 25, 2021