Maternal-fetal Medicine | Page 10 of 22 | Links Medicus Content Curation & Alerts in Medicine

Does milking the umbilical cord benefit infants non-vigorous at birth?

A new RCT by @NeoAnup published in @AJOG_thegray evaluates this https://t.co/M5RRAzdEHz #neoEBM #neoTwitter #EBNEOAlerts pic.twitter.com/mZnSKjcGNt

— Evidence-Based Neo (@EBNEO) August 20, 2022

Cohort Study | Associations between maternal antenatal corticosteroid treatment and psychological developmental and neurosensory disorders in children.

6 Sep, 2022 | 14:26h | UTC

Associations Between Maternal Antenatal Corticosteroid Treatment and Psychological Developmental and Neurosensory Disorders in Children – JAMA Network Open

Commentary: Toxicity of antenatal steroids on the developing brain – Neonatal Research

Commentary on Twitter

Maternal antenatal corticosteroid treatment-exposure, compared with nonexposure, was associated with higher rates of psychological development and neurosensory disorders in children followed from birth through 12 years of age. #OAResearch https://t.co/PuVSBTASze

— JAMA Network Open (@JAMANetworkOpen) August 24, 2022

Cohort Study | Dolutegravir in pregnancy as compared with current HIV regimens.

1 Sep, 2022 | 11:55h | UTC

Dolutegravir in Pregnancy as Compared with Current HIV Regimens in the United States – New England Journal of Medicine (link to abstract – $ for full-text)

RCT | 72 weeks post-partum follow-up of dolutegravir versus efavirenz initiated in late pregnancy.

WHO Recommends Dolutegravir as Preferred HIV Treatment Option in All Populations

Week 96 results from a RCT: Efficacy and safety of dolutegravir or darunavir combined with lamivudine plus either zidovudine or tenofovir for second-line treatment of HIV infection.

RCT: Efficacy and safety of switching to the 2-drug regimen Dolutegravir/Lamivudine vs. continuing a 3- or 4-Drug regimen for maintaining virologic suppression in adults living with HIV-1.

RCT: Low-cost, easy to take antiretroviral treatment based on Dolutegravir as first- or second-Line therapy found to be non-inferior to standard care for treating HIV-1 infection in children.

RCT: Dolutegravir or Darunavir in combination with Zidovudine or Tenofovir to treat HIV.

Randomized controlled trial compared three antiretroviral regimens started in pregnant women with HIV

Randomized Trial: Switching to Dolutegravir/Lamivudine Two-Drug Regimen Noninferior to Continuing a Tenofovir Alafenamide–Based Three- or Four-Drug Regimen for Maintenance of Virologic Suppression in Adults With HIV-1

Commentary on Twitter

In this study involving 1257 pregnancies among persons treated for HIV-1 infection during pregnancy, dolutegravir was better at suppressing viral loads than other regimens, without evident safety concerns. https://t.co/CnShoao995 pic.twitter.com/Qne24I1482

— NEJM (@NEJM) August 31, 2022

Relationship between maternal caffeine and coffee intake and pregnancy loss: a grading of recommendations assessment, development, and evaluation-assessed, dose-response meta-analysis of observational studies.

31 Aug, 2022 | 11:35h | UTC

Relationship between maternal caffeine and coffee intake and pregnancy loss: A grading of recommendations assessment, development, and evaluation-assessed, dose-response meta-analysis of observational studies – Frontiers in Nutrition

Study shows an increasing incidence of hypertensive disorders in pregnancy.

30 Aug, 2022 | 11:52h | UTC

Association of Birth Year of Pregnant Individuals With Trends in Hypertensive Disorders of Pregnancy in the United States, 1995-2019 – JAMA Network Open

Commentaries:

Increased incidence of hypertensive disorders of pregnancy in young Americans – News Medical

Hypertensive Disorders in Pregnancy on the Rise – AJMC

Commentary on Twitter

Independent birth cohort effect on rates of hypertensive disorders of pregnancy higher incidence in younger generations and persistent racial and ethnic disparities. Increased awareness even among young pregnant people is needed. #OAResearch https://t.co/wNwIZTYLHZ

— JAMA Network Open (@JAMANetworkOpen) August 24, 2022

M-A | Adverse pregnancy and birth outcomes associated with Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum.

29 Aug, 2022 | 12:06h | UTC

Adverse pregnancy and birth outcomes associated with Mycoplasma hominis, Ureaplasma urealyticum and Ureaplasma parvum: a systematic review and meta-analysis – BMJ Open

M-A | Family history of psychiatric disorders as a risk factor for maternal postpartum depression.

26 Aug, 2022 | 13:04h | UTC

Family History of Psychiatric Disorders as a Risk Factor for Maternal Postpartum Depression: A Systematic Review and Meta-analysis – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries:

Postpartum Depression More Likely in New Moms With Family History of Psychiatric Disorders – Psychiatric News Alert

Family History of Mental Illness Ups Odds for Postpartum Depression – HealthDay

Commentary on Twitter

Based on 26 studies from 18 countries, this systematic review and meta-analysis highlighted that mothers with a family history of any psychiatric disorder had an almost doubled risk of developing postpartum #depression compared to mothers without. https://t.co/zEJd6YHe71

— JAMA Psychiatry (@JAMAPsych) August 20, 2022

Cohort Study | Characteristics of prescription opioid analgesics in pregnancy and risk of neonatal opioid withdrawal syndrome in newborns.

25 Aug, 2022 | 12:02h | UTC

Characteristics of Prescription Opioid Analgesics in Pregnancy and Risk of Neonatal Opioid Withdrawal Syndrome in Newborns – JAMA Network Open

RCT | In women at risk of preterm delivery, half dose antenatal Dexamethasone was NOT noninferior compared to full dose Dexamethasone on neonatal outcomes.

24 Aug, 2022 | 14:20h | UTC

Neonatal outcomes for women at risk of preterm delivery given half dose versus full dose of antenatal betamethasone: a randomised, multicentre, double-blind, placebo-controlled, non-inferiority trial – The Lancet (link to abstract – $ for full-text)

Commentary on Twitter

On 50th anniversary of Liggins & Howie's discovery of benefits of antenatal steroids for preterm birth, new study in @TheLancet confirms full dose (11.4 mg x 2) of betamethasone is necessary for optimum benefit. https://t.co/VgjtprM0W8 #neoTwitter #obstetrics @EBNEO @ESPR_EBN pic.twitter.com/Cl1GbzWoRl

— Atul Malhotra (@Atul_Monash) August 19, 2022

Calcium for pre-eclampsia prevention | A systematic review and network meta-analysis to guide personalized antenatal care.

22 Aug, 2022 | 11:47h | UTC

Calcium for pre-eclampsia prevention: A systematic review and network meta-analysis to guide personalised antenatal care – British Journal of Obstetrics and Gynaecology

Commentary on Twitter

Meta-analysis finds that low-dose calcium supplementation is as effective as high-dose calcium in halving the risk of pre-eclampsia when baseline calcium intake is low.https://t.co/ZejDiB4vNE

— BJOG (@BJOGTweets) June 8, 2022

RCT | A lower glycemic criteria in not better than higher glycemic criteria for the diagnosis of gestational diabetes.

18 Aug, 2022 | 13:04h | UTC

Lower versus Higher Glycemic Criteria for Diagnosis of Gestational Diabetes – New England Journal of Medicine (link to abstract – $ for full-text)

Commentary: Pros and cons with lower vs higher threshold for gestational diabetes diagnosis – medwire News

Commentary on Twitter (thread – click for more)

1/ Overdiagnosis of Gestational Diabetes (GDM): New large randomized trial compared broader/narrower criteria -> NO improvement in mother/baby outcomes BUT x2 increase in % pregnant women labelled as GDM. Time to reconsider GDM testing – https://t.co/xrr0XrdhaZ

— Paul Glasziou (@PaulGlasziou) August 18, 2022

Retrospective cohort study | Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy.

18 Aug, 2022 | 12:51h | UTC

Risk of preterm birth, small for gestational age at birth, and stillbirth after covid-19 vaccination during pregnancy: population based retrospective cohort study – The BMJ

News Release: No link between COVID-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth – British Medical Journal

SARS-CoV-2 infection and COVID-19 vaccination in pregnancy – Nature Reviews Immunology

Cohort Study: COVID-19 vaccination during early pregnancy was not associated with increased risk of congenital fetal anomalies.

Retrospective Cohort: A population-based study in Sweden and Norway did not find an increased risk of pregnancy complications after COVID-19 vaccination.

WHO Questions and Answers: COVID-19 vaccines and pregnancy.

COVID vaccines safely protect pregnant people: the data are in.

COVID-19 vaccination in pregnancy—number needed to vaccinate to avoid harm.

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

Commentary on Twitter

No link between covid-19 vaccination in pregnancy and higher risk of preterm birth or stillbirth, finds study in @bmj_latest https://t.co/XLgFeoWVsp

Findings can help guide decision making about #covid-19 #vaccination during #pregnancy pic.twitter.com/9Pxm0Yv2Mf

— BMJ Group (@bmj_company) August 18, 2022

M-A | Interventions for the prevention or treatment of epidural-related maternal fever.

18 Aug, 2022 | 12:45h | UTC

Interventions for the prevention or treatment of epidural-related maternal fever: a systematic review and meta-analysis – British Journal of Anaesthesia

Preventing stillbirth: a review of screening and prevention strategies.

18 Aug, 2022 | 12:36h | UTC

Preventing Stillbirth: A Review of Screening and Prevention Strategies – Maternal-Fetal Medicine

Trends in active treatment of live-born neonates between 22 weeks 0 days and 25 weeks 6 days by gestational age and maternal race and ethnicity in the US, 2014 to 2020.

18 Aug, 2022 | 12:32h | UTC

Trends in Active Treatment of Live-born Neonates Between 22 Weeks 0 Days and 25 Weeks 6 Days by Gestational Age and Maternal Race and Ethnicity in the US, 2014 to 2020 – JAMA (link to abstract – $ for full-text)

Commentaries:

Study finds racial, ethnic disparities in rate of medical intervention among earliest premature babies – The Ohio State University

Active Treatment for Extremely Preterm Babies on the Rise — Yet researchers find racial and ethnic disparities in treatment initiation – MedPage Today (free registration required)

Commentary on Twitter

From 2014 to 2020 in the US, the frequency of active treatment among neonates born alive between 22 weeks 0 days and 25 weeks 6 days significantly increased, and there were differences in rates of active treatment by race and ethnicity. https://t.co/Xflqhxklul #Research

— JAMA (@JAMA_current) August 17, 2022