General Gynecology
USPSTF reaffirms recommendation against serologic screening for genital herpes infection
15 Feb, 2023 | 16:17h | UTCSummary: The US Preventive Services Task Force (USPSTF) recommends against routine screening for genital herpes infection in asymptomatic adolescents, adults, and pregnant women, as the potential harms of such screening outweigh the benefits. This recommendation is based on a systematic evaluation of the available evidence, and the USPSTF has moderate certainty in its conclusion.*
Evidence Report: Serologic Screening for Genital Herpes: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA
Editorials:
Reducing HSV-2 Morbidity and MortalityRoutine Serologic Screening Still Not the Best Answer – JAMA
Reaffirmed USPSTF Recommendation Against Serologic Screening for Genital Herpes: Empowering Clinicians and Reducing Potential Harm – JAMA Dermatology (free for a limited period)
Author Interview: Serologic Screening for Genital Herpes Infection – JAMA
JAMA Patient Page: Screening for Genital Herpes
*Note: This summary was created through the collaboration of a medical editor and ChatGPT.
RCT | Gefitinib plus MTX not better than MTX alone to treat tubal ectopic pregnancy
8 Feb, 2023 | 12:43h | UTC
Commentary from the author on Twitter (thread – click for more)
See our @Gem3Study in @TheLancet: no benefit of adding gefitinib to methotrexate to treat #ectopic pregnancy but important data to inform guidelines on clinical outcomes after methotrexate https://t.co/xgtA4oLBJd @ProfStephenTong @GynaeResearcher @TheEPT @MRC_CRH @EdinUniMedia pic.twitter.com/g96Z8B400a
— Andrew Horne (@horne_research) February 2, 2023
Under a Creative Commons Attribution (CC BY 4.0) license
M-A | Risk of endometrial cancer in postmenopausal women in relation to ultrasonographic endometrial thickness
8 Feb, 2023 | 12:21h | UTCRisk of endometrial cancer in asymptomatic postmenopausal women in relation to ultrasonographic endometrial thickness: systematic review and diagnostic test accuracy meta-analysis – American Journal of Obstetrics & Gynecology (link to abstract – $ for full-text)
Commentary on Twitter
AJOG Systematic Review: Risk of endometrial cancer in asymptomatic postmenopausal women in relation to ultrasonographic endometrial thickness: systematic review and diagnostic test accuracy meta-analysis https://t.co/uxPx8Jr160 pic.twitter.com/LugkrnKmjr
— AJOG (@AJOG_thegray) December 30, 2022
RCT | Laser no better than sham treatment for genitourinary syndrome of menopause
8 Feb, 2023 | 12:17h | UTCLaser versus sham for genitourinary syndrome of menopause: A randomised controlled trial – BJOG (link to abstract – $ for full-text)
Invited commentary: Laser therapy for genitourinary syndrome of menopause: Emperor’s new clothes or a meaningful advance? – BJOG
Related:
M-A | Carbon dioxide laser vs. vaginal estrogen for genitourinary syndrome of menopause.
Perspective: From vaginal laser treatment to spa breaks – it’s the great menopause gold rush.
SR | Interventions to improve health and the determinants of health among sex workers in high-income countries
1 Feb, 2023 | 13:25h | UTCEditorial: Sex workers health: time to act
Commentary from the author on Twitter (thread – click for more)
New Paper! Our SR in @TheLancetPH summarises evidence for health & social interventions in sex worker populations in HICs https://t.co/TSe9qv4oKP Great team inc @DrLucypotter @MollyBradbury14 @GraceyOutreach @Kitdempsey @rob_aldridge @BintyRock @SerenaLuchenski🧵below…1/4 pic.twitter.com/P6Bx3rFfHw
— Luke Johnson, MD, MSc, FFPH (@luke_a_johnson) November 3, 2022
Syphilis in dermatology: recognition and management
31 Jan, 2023 | 14:01h | UTCSyphilis in Dermatology: Recognition and Management – American Journal of Clinical Dermatology (if the link is paywalled, try this one in PMC)
M-A | Permanent compared with absorbable suture in apical prolapse surgery
30 Jan, 2023 | 00:29h | UTCPermanent Compared With Absorbable Suture in Apical Prolapse Surgery: A Systematic Review and Meta-analysis – Obstetrics & Gynecology (free for a limited period)
Commentary on Twitter
Should you use permanent or absorbable suture for apical prolapse? https://t.co/G8nkMQgUQV pic.twitter.com/LwBwyS1WV8
— The Green Journal (@greenjrnl) January 27, 2023
Cohort Study | Incidence and impact of anticoagulation-associated abnormal menstrual bleeding after VTE
27 Jan, 2023 | 12:04h | UTCInvited Commentary: The burden of heavy menstrual bleeding – Blood
Commentary on Twitter
Incidence and impact of anticoagulation-associated abnormal menstrual bleeding in women after venous thromboembolism https://t.co/IEftFzyvRl pic.twitter.com/m09sP14inN
— Blood Journal (@BloodJournal) October 26, 2022
Meta-analysis reaffirms benefits of O-RADS MRI for diagnosing indeterminate adnexal lesions
24 Jan, 2023 | 14:05h | UTCOriginal Study: O-RADS MRI: A Systematic Review and Meta-Analysis of Diagnostic Performance and Category-wise Malignancy Rates – Radiology (link to abstract – $ for full-text)
Commentary on Twitter
A meta-analysis of 4520 adnexal lesions from 12 studies showed that MRI O-RADS has a 92% summary sensitivity and a 91% summary specificity in characterizing lesions that are indeterminate at US. https://t.co/WSJVQUiM4T pic.twitter.com/kssAK2s02N
— Radiology (@radiology_rsna) November 23, 2022
Review | Advances in the diagnosis and early management of gestational trophoblastic disease
19 Jan, 2023 | 14:08h | UTCAdvances in the diagnosis and early management of gestational trophoblastic disease – BMJ Medicine
Review | Surgical site infection prevention
18 Jan, 2023 | 14:31h | UTCSurgical Site Infection Prevention: A Review – JAMA (free for a limited period)
Author interview: Surgical Site Infection Prevention – JAMA
Related:
Global guidelines on the prevention of surgical site infection – World Health Organization
AAOS Guideline: Prevention of surgical site infections after major extremity trauma.
RCT | Effect of pessary vs. surgery in patients with symptomatic pelvic organ prolapse
12 Jan, 2023 | 13:16h | UTCEffect of Pessary vs Surgery on Patient-Reported Improvement in Patients With Symptomatic Pelvic Organ Prolapse: A Randomized Clinical Trial – JAMA (link to abstract – $ for full-text)
Commentary: Findings question value of pessary for pelvic organ prolapse – MDedge
Commentary on Twitter
In this study, among patients with symptomatic pelvic organ prolapse, an initial strategy of pessary therapy, compared with surgery, did not meet criteria for noninferiority with regard to patient-reported improvement at 24 months. https://t.co/PRb7iclR8O pic.twitter.com/ex3SSmLqyz
— JAMA (@JAMA_current) December 20, 2022
SR | No-test medication abortion
10 Jan, 2023 | 14:02h | UTCNo-Test Medication Abortion: A Systematic Review – Obstetrics & Gynecology
Commentary on Twitter
From Shapiro et al: medication abortion performed without prior pelvic exam or ultrasound is safe and effective. #free #podcast https://t.co/xightukWW0 pic.twitter.com/P6bajuKZDU
— The Green Journal (@greenjrnl) December 21, 2022
WHO updates recommendations on HPV vaccination schedule
9 Jan, 2023 | 14:57h | UTCNews Release: WHO updates recommendations on HPV vaccination schedule – World Health Organization
Guideline: Human papillomavirus vaccines: WHO position paper, December 2022 – World Health Organization
Commentaries:
WHO supports 1-dose HPV vaccine strategy – CIDRAP
Commentary on Twitter
🆕 WHO has revised its recommendations on possible schedules for human papillomavirus (#HPV) vaccines & now recommends:
👉1 or 2-doses for girls & women aged 9-20
👉2 doses with a 6-month interval for women 21+https://t.co/m0KZyH6sPR pic.twitter.com/W4PeS4raV9— World Health Organization (WHO) (@WHO) December 21, 2022
Review | Human papillomavirus vaccination and cervical cancer risk.
16 Dec, 2022 | 13:26h | UTCHuman papillomavirus vaccination and cervical cancer risk – The BMJ
Review | Pathophysiology, diagnosis, and management of endometriosis.
16 Dec, 2022 | 13:23h | UTCPathophysiology, diagnosis, and management of endometriosis – The BMJ
Endocervical sampling in women with suspected cervical neoplasia: a meta-analysis of diagnostic test accuracy studies.
9 Dec, 2022 | 13:12h | UTC
Cohort Study | Relationship between unremoved cervical polyp in pregnancy and spontaneous preterm birth.
9 Dec, 2022 | 13:05h | UTC
Commentary on Twitter
Relationship between unremoved cervical polyp in pregnancy and spontaneous preterm birth https://t.co/Z2bq81Xoqr pic.twitter.com/JXALaGxyFO
— AJOG (@AJOG_thegray) December 8, 2022
RCT | Effect of intraoperative Esketamine infusion on postoperative sleep disturbance after gynecological laparoscopy.
7 Dec, 2022 | 14:15h | UTC
Commentary on Twitter
https://twitter.com/JAMANetworkOpen/status/1598376382849028118
German Guidelines on Sarcoma of the Uterus.
6 Dec, 2022 | 13:50h | UTCCohort Study | Viral shedding 1 year following first-episode genital HSV-1 infection.
5 Dec, 2022 | 00:14h | UTCViral Shedding 1 Year Following First-Episode Genital HSV-1 Infection – JAMA (free for a limited period)
Editorial: Shedding Patterns of Genital Herpes Simplex Virus Infections – JAMA (free for a limited period)
News Release: Viral shedding ebbs over time with HSV-1 genital infections – University of Washington School of Medicine
Commentary: Viral Shedding Common After First-Episode Genital HSV-1 Infection – HealthDay
Commentary on Twitter
In this study, genital herpes simplex virus type 1 (HSV-1) shedding was frequent after first-episode genital HSV-1 and declined rapidly during the first year of infection. https://t.co/CsVr1tNfNQ
— JAMA (@JAMA_current) October 26, 2022
Perspective | Push to use antibiotics to prevent sexually transmitted infections raises concerns.
2 Dec, 2022 | 14:27h | UTCPush to use antibiotics to prevent sexually transmitted infections raises concerns – Nature
Review | Infectious complications of abortion.
29 Nov, 2022 | 13:56h | UTCInfectious Complications of Abortion – Open Forum Infectious Diseases
Consensus Paper | General approaches to medical management of menstrual suppression.
27 Nov, 2022 | 22:21h | UTC
RCT | Opioid-reduced anesthesia based on esketamine in gynecological day surgery.
25 Nov, 2022 | 12:29h | UTC