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Guidelines & Reports

Guideline for the laboratory diagnosis of iron deficiency in adults (excluding pregnancy) and children.

25 Nov, 2021 | 10:31h | UTC

Guideline for the laboratory diagnosis of iron deficiency in adults (excluding pregnancy) and children – British Journal of Haematology

 

Clinical practice guideline for the treatment of malignant ascites.

25 Nov, 2021 | 10:28h | UTC

Clinical practice guideline for the treatment of malignant ascites: section summary in Clinical Practice Guideline for peritoneal dissemination (2021) – International Journal of Clinical Oncology

 

WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19.

24 Nov, 2021 | 08:51h | UTC

News Release: WHO issues guidelines on the treatment of children with multisystem inflammatory syndrome associated with COVID-19 – World Health Organization

Guideline: Living guidance for clinical management of COVID-19 – World Health Organziation

Related:

An Update on Multisystem Inflammatory Syndrome in Children Related to SARS-CoV-2.

Ten Things to Know About Multisystem Inflammatory Syndrome in Children (MIS-C).

Cohort study: long term follow-up showed most patients with post–COVID-19 Multisystem Inflammatory Syndrome in Children had good outcomes with no significant medium- or long-term sequelae.

Kawasaki Disease and Multisystem Inflammatory Syndrome in Children: An Overview and Comparison.

Cohort study: Six month follow-up of Multisystem Inflammatory Syndrome in Children.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, there was no evidence that recovery differed after primary treatment with intravenous immune globulin (IVIG) alone, IVIG plus glucocorticoids, or glucocorticoids alone.

Cohort study: Among children with Multisystem Inflammatory Syndrome (MIS-C) associated with Covid-19, initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids was associated with a lower risk of new or persistent cardiovascular dysfunction than IVIG alone.

Cohort study showed that the incidence of Multisystem Inflammatory Syndrome in Children (MIS-C) was 316 persons per 1 000 000 SARS-CoV-2 infections in persons younger than 21 years. The incidence was higher among Black, Hispanic or Latino, and Asian or Pacific Islander persons.

Cohort study showed good recovery for most children 6 months after Pediatric Inflammatory Multisystem Syndrome (PIMS-TS) associated with SARS-CoV-2.

Epidemiology of Multisystem Inflammatory Syndrome in Children: A Step Closer to Understanding Who, Where, and When

Neurologic involvement in children and adolescents with COVID-19 or Multisystem Inflammatory Syndrome

Clinical Update: Acute covid-19 and multisystem inflammatory syndrome in children

Differences in characteristics and outcomes of children and adolescents with Multisystem Inflammatory Syndrome in Children (MIS-C) vs. severe acute COVID-19

Cutaneous findings in SARS-CoV-2-associated Multisystem Inflammatory Disease in Children (MIS-C)

SR: Multisystem inflammatory syndrome in children related to COVID-19

Observational study: The combination of Immunoglobulins + Methylprednisolone was associated with a better course of fever compared to Immunoglobulins alone in Multisystem Inflammatory Syndrome in children

ACR Guidance for pediatric patients with multisystem inflammatory syndrome in children associated with SARS‐CoV‐2

New systematic review of Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 infection summarizes the clinical features, management, and outcomes of the disease, showing favorable outcomes for the majority of children

 

AGA Clinical practice update on management of chronic gastrointestinal pain in disorders of gut–brain interaction.

24 Nov, 2021 | 08:42h | UTC

AGA Clinical Practice Update on Management of Chronic Gastrointestinal Pain in Disorders of Gut–Brain Interaction: Expert Review – Clinical Gastroenterology and Hepatology

 

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab.

24 Nov, 2021 | 08:36h | UTC

Three Neurologic Societies, Including the AAN, Issue Strong Position Statement on Aducanumab – Neurology Today

See statement: Decisions With Patients and Families Regarding Aducanumab in Alzheimer Disease, With Recommendations for Consent: AAN Position Statement – Neurology

Related:

Editorial: Aducanumab for Alzheimer’s disease?

FDA approvement of Alzheimer’s drug sparks controversy among doctors.

 

Commentary on Twitter

 

ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.

23 Nov, 2021 | 08:40h | UTC

ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease – American Journal of Gastroenterology

 

Commentary on Twitter (thread – click for more)

 

GRADE Guidance 24. Optimizing the integration of randomized and non-randomized studies of interventions in evidence syntheses and health guidelines.

23 Nov, 2021 | 08:38h | UTC

GRADE Guidance 24. Optimizing the integration of randomized and non-randomized studies of interventions in evidence syntheses and health guidelines – Journal of Clinical Epidemiology

 

Commentary on Twitter

 

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections.

23 Nov, 2021 | 08:45h | UTC

IDSA Guidance on the Treatment of Antimicrobial-Resistant Gram-Negative Infections – Infectious Diseases Society of America

 

Commentary on Twitter

 

EuGMS Guidance: Management of post-acute COVID-19 patients in geriatric rehabilitation.

21 Nov, 2021 | 23:14h | UTC

Management of post-acute COVID-19 patients in geriatric rehabilitation: EuGMS guidance – European Geriatric Medicine

Related:

Addressing Post-COVID Symptoms: A Guide for Primary Care Physicians.

Global surveillance, research, and collaboration needed to improve understanding and management of long COVID.

Provocative study suggests that persistent physical symptoms after COVID-19 infection may be associated more with the belief in having been infected with SARS-CoV-2 than with having laboratory-confirmed COVID-19 infection.

Update to post-acute sequelae of SARS-CoV-2 infection: Caring for the ‘long-haulers’.

Systematic Review: Short-term and long-term rates of postacute sequelae of SARS-CoV-2 infection.

WHO Consensus: A clinical case definition of post COVID-19 condition (Long Covid).

Characterizing long COVID: a living systematic review.

Long Covid – The illness narratives.

New guidelines to help doctors manage long COVID patients published.

M-A: More than 50 long-term effects of COVID-19. (several articles on the subject)

 

Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.

21 Nov, 2021 | 23:01h | UTC

Updates on Age to Start and Stop Colorectal Cancer Screening: Recommendations From the U.S. Multi-Society Task Force on Colorectal Cancer – Gastroenterology

News release: US Multi-Society Task Force on colorectal cancer releases updated screening recommendations - American Gastroenterological Association

Related:

State of the Art Review: Screening and prevention of colorectal cancer.

USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.

ACG Clinical Guidelines: Start colorectal cancer screening at 45

 

Clinical Guideline Highlights for the Hospitalist: Management of Upper Gastrointestinal and Ulcer Bleeding.

21 Nov, 2021 | 22:44h | UTC

Clinical Guideline Highlights for the Hospitalist: Management of Upper Gastrointestinal and Ulcer Bleeding – Journal of Hospital Medicine (free for a limited period)

Original Guideline: ACG Clinical Guideline: Upper Gastrointestinal and Ulcer Bleeding – RBC transfusion at a threshold of 7 g/dL; Erythromycin infusion is suggested before endoscopy; and endoscopy is suggested within 24 hours after presentation.

 

Global, regional, and national causes of under-5 mortality in 2000–19: an updated systematic analysis with implications for the Sustainable Development Goals.

19 Nov, 2021 | 10:40h | UTC

Global, regional, and national causes of under-5 mortality in 2000–19: an updated systematic analysis with implications for the Sustainable Development Goals – The Lancet Child & Adolescent Health

 

Commentary on Twitter

 

Consensus and expert recommendations: basic ultrasound head-to-toe skills for intensivists in the general and neuro intensive care unit population.

19 Nov, 2021 | 10:37h | UTC

Basic ultrasound head-to-toe skills for intensivists in the general and neuro intensive care unit population: consensus and expert recommendations of the European Society of Intensive Care Medicine

 

Commentary on Twitter

 

WHO global report on trends in prevalence of tobacco use 2000-2025.

19 Nov, 2021 | 10:43h | UTC

WHO global report on trends in prevalence of tobacco use 2000-2025, fourth edition – World Health Organization

News Release: Tobacco use falling: WHO urges countries to invest in helping more people to quit tobacco – World Health Organization

 

Commentary on Twitter

 

AAP Clinical Report: Biologics for Asthma and Allergic Skin Diseases in Children.

19 Nov, 2021 | 10:34h | UTC

Biologics for Asthma and Allergic Skin Diseases in Children – Pediatrics

 

AAP Clinical Report: Promoting Human Milk and Breastfeeding for the Very Low Birth Weight Infant.

19 Nov, 2021 | 10:35h | UTC

Promoting Human Milk and Breastfeeding for the Very Low Birth Weight Infant – Pediatrics

 

NICE Guideline | Heart valve disease presenting in adults: investigation and management.

18 Nov, 2021 | 08:44h | UTC

Heart valve disease presenting in adults: investigation and management – National Institute for Health and Care Excellence

Related Guidelines:

#ESCCongress – 2021 ESC/EACTS Guidelines for the management of valvular heart disease – in the new guidelines, more patients are eligible for surgical and transcatheter interventions, based not only on symptoms but also on imaging criteria.

2020 ACC/AHA Guideline for the management of patients with valvular heart disease

 

New ACR radiation diagnostic reference levels for top 10 pediatric CT exams.

18 Nov, 2021 | 08:31h | UTC

News Release: New Radiation Diagnostic Reference Levels for Top 10 Pediatric CT Exams – American College of Radiology

Original Guideline: U.S. Diagnostic Reference Levels and Achievable Doses for 10 Pediatric CT Examinations – Radiology

Commentary: ACR releases new benchmarks to help radiology departments optimize radiation dose levels – Health Imaging

 

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic.

17 Nov, 2021 | 08:56h | UTC

ESC guidance for the diagnosis and management of cardiovascular disease during the COVID-19 pandemic – European Heart Journal

Part 1—epidemiology, pathophysiology, and diagnosis

Part 2—care pathways, treatment, and follow-up

News release: European Society of Cardiology COVID-19 guidance launched – European Society of Cardiology

 

Commentaries on Twitter

 

AAN Guideline: Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease.

17 Nov, 2021 | 08:32h | UTC

Dopaminergic Therapy for Motor Symptoms in Early Parkinson Disease Practice Guideline Summary – Neurology

News Release: AAN Issues Guideline for Treatment of Early Parkinson’s Disease – American Academy of Neurology

 

Position Statement: Preoperative Care for Cataract Surgery – “In spite of evidence debunking the utility of testing before cataract surgery, studies suggest that medical testing and the use of medical consultations before cataract surgery continue to increase”.

17 Nov, 2021 | 08:33h | UTC

Preoperative Care for Cataract Surgery: The Society for Ambulatory Anesthesia Position Statement – Anesthesia & Analgesia

 

Commentary on Twitter

 

IDSA/ASM Consensus Review Document: Clinical and Infection Prevention Applications of SARS-CoV-2 Genotyping.

16 Nov, 2021 | 08:50h | UTC

Clinical and Infection Prevention Applications of SARS-CoV-2 Genotyping: An IDSA/ASM Consensus Review Document – Clinical Infectious Diseases

News Release: New review article outlines potential of SARS-CoV-2 genetic sequencing in patient care – American Society for Microbiology

 

New WHO report maps barriers to insulin availability and suggests actions to promote universal access – “100 years after its discovery, insulin still out of reach for many living with diabetes”.

16 Nov, 2021 | 08:34h | UTC

News Release: New WHO report maps barriers to insulin availability and suggests actions to promote universal access – World Health Organization

Report: Keeping the 100-year-old promise: making insulin access universal – World Health Organization

Commentary: Half the People Living with Diabetes Can’t Afford Insulin, WHO Report Shows – Health Policy Watch

Related:

Editorial | Insulin for all: a hope yet to be realized.

One hundred years of insulin therapy.

The state of diabetes treatment coverage in 55 low-income and middle-income countries – fewer than one in ten people with diabetes in LMICs receive comprehensive care such as low-cost medicines to reduce blood sugar, blood pressure and cholesterol levels, in addition to counseling on diet, exercise and weight.

 

Commentary on Twitter (thread – click for more)

 

2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations.

16 Nov, 2021 | 08:37h | UTC

2021 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations: Summary From the Basic Life Support; Advanced Life Support; Neonatal Life Support; Education, Implementation, and Teams; First Aid Task Forces; and the COVID-19 Working Group – Circulation (for an HTML version click here)

Top Things to Know: International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations (CoSTR) – American Heart Association

 

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019.

14 Nov, 2021 | 19:45h | UTC

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 – The Lancet

Commentary: Nearly two-thirds of those who died young in 2019 were male, research finds – The Guardian

 

Commentary on Twitter (thread – click for more)

 

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