Global & Public Health (all articles)
Long Covid: 39% of patients report persistent symptoms more than seven months after diagnosis of COVID-19 in an outpatient setting.
13 Jul, 2021 | 09:57h | UTCCommentaries: Long COVID symptoms in a third of people with COVID-19 – American College of Physicians AND Covid-19: 1-in-3 Patients Reported Long-Hauler Symptoms – Physician’s Weekly
Commentary on Twitter
A new prospective cohort study of >400 people with mild to moderate (outpatient) covid at 7-9 months: nearly 1 of 3 had persistent symptoms #LongCovid @AnnalsofIM
https://t.co/ix1Hhsm0iZ
by @mayssamnehme and colleagues pic.twitter.com/Uc4UEclDvA— Eric Topol (@EricTopol) July 5, 2021
WHO warns against mixing and matching COVID vaccines.
13 Jul, 2021 | 09:53h | UTCWHO warns against mixing and matching COVID vaccines – Reuters
Commentary: WHO cautions data still limited on mixing COVID-19 vaccines, but Canadian officials say it’s OK – CTV News
Related: Germany issues world’s strongest recommendation for mixing Covid-19 vaccines. AND [Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”. AND Perspective | Can I get AstraZeneca now and Pfizer later? Why mixing and matching COVID vaccines could help solve many rollout problems. AND RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects. AND Should you mix and match COVID-19 vaccines? Scientists are seeking answers
Commentary on Twitter
The World Health Organization's chief scientist on Monday advised against people mixing and matching COVID-19 vaccines from different manufacturers, calling it a "dangerous trend" since there was little data available about the health impact. https://t.co/Oog6fWDSMz
— Reuters Health (@Reuters_Health) July 13, 2021
[Preprint] Long Covid: Persistent symptoms following SARS-CoV-2 infection in a random community sample of 508,707 people.
13 Jul, 2021 | 09:55h | UTCCommentary: Study explores the prevalence of long COVID in England – News Medical
Extremely rare cases of Guillain-Barré reported with Johnson & Johnson vaccine for Covid-19.
13 Jul, 2021 | 09:48h | UTCJ&J’s Covid-19 vaccine may trigger neurological condition in rare cases, FDA says – STAT
See also: Johnson & Johnson Vaccine Is Linked To Neurological Disorder In Extremely Rare Cases – NPR AND F.D.A. Attaches Warning of Rare Nerve Syndrome to Johnson & Johnson Vaccine – The New York Times
Pro-Con Debate | Should we delay covid-19 vaccination in children?
13 Jul, 2021 | 09:51h | UTCShould we delay covid-19 vaccination in children? – The BMJ
News release: Should we delay COVID-19 vaccination in children? – British Medical Journal
Commentary on Twitter
Covid-19 vaccines in adults have been remarkably effective. There is good reason to expect that the same will be true in children.
A group of authors discuss the pros and cons of vaccinating children against covid-19 https://t.co/TOEI67YPeH
— The BMJ (@bmj_latest) July 9, 2021
New CDC Guidance for COVID-19 prevention in kindergarten schools says safely returning to in-person instruction is a priority.
12 Jul, 2021 | 03:11h | UTCCommentaries: Updated CDC schools guidance prioritizes in-person learning, even if all Covid-19 safety measures aren’t in place – CNN AND The C.D.C. Issues New School Guidance, With Emphasis on Full Reopening – The New York Times AND New CDC guidance says fully vaccinated teachers and students don’t need to wear masks indoors – CNBC AND CDC calls for reopening schools fully, recommends masking – CIDRAP
Related: COVID and schools: the evidence for reopening safely – Nature
[Preprint] Study confirms children’s extremely low risk of death from Covid-19 – “99·995% of children and young people with a positive SARS-CoV-2 test survived”.
12 Jul, 2021 | 03:12h | UTCCommentaries: Risks of severe illness in children from COVID-19 shown to be very low in largest study yet – University of Liverpool AND Covid: Children’s extremely low risk confirmed by study – BBC
Related study from the same group (preprint): Risk factors for intensive care admission and death amongst children and young people admitted to hospital with COVID-19 and PIMS-TS in England during the first pandemic year – medRxiv
A correlate of protection for SARS-CoV-2 vaccines is urgently needed – “Recent studies suggest that neutralizing antibodies could serve as a correlate of protection for vaccines against SARS-CoV-2 in humans”.
12 Jul, 2021 | 03:03h | UTCA correlate of protection for SARS-CoV-2 vaccines is urgently needed – Nature Medicine
Public Health England: COVID-19 vaccines highly effective in clinical risk groups.
12 Jul, 2021 | 03:06h | UTCCOVID-19 vaccines highly effective in clinical risk groups – Public Health England
Commentaries: Covid vaccines do work well in clinically vulnerable – BBC AND Public Health England says Pfizer, AstraZeneca vaccines effective in high-risk groups – Reuters
Commentary on Twitter (thread – click for more)
NEWS: #COVID19 #vaccines highly effective in clinical risk groupshttps://t.co/mkVnxTqOrJ pic.twitter.com/M6Me98SRln
— Public Health England (@PHE_uk) July 9, 2021
Pfizer says it’s time for a Covid booster; FDA and CDC say not so fast.
12 Jul, 2021 | 03:08h | UTCPfizer says it’s time for a Covid booster; FDA and CDC say not so fast – CNN
See also: CDC, FDA contradict Pfizer on COVID-19 vaccine booster – CIDRAP AND Do I need a COVID-19 booster shot? 6 questions answered on how to stay protected – The Conversation AND Pfizer suggests booster shots will be needed this year, but government officials say science will dictate the timing – The Washington Post AND Pfizer to seek OK for 3rd vaccine dose; shots still protect – Associated Press AND Citing the Delta Variant, Pfizer Will Pursue Booster Shots and a New Vaccine – The New York Times (a few articles per month are free) AND Question open on need for COVID booster shot, data awaited, WHO says – Reuters
Can we stretch existing Covid vaccines to inoculate more people? Experts are divided.
12 Jul, 2021 | 03:05h | UTCCan we stretch existing Covid vaccines to inoculate more people? Experts are divided – STAT
See also: Quarter-dose of Moderna COVID vaccine still rouses a big immune response
Lambda, the Newest WHO Variant of Interest, is Now in 29 Countries.
12 Jul, 2021 | 03:06h | UTCLambda, the Newest WHO Variant of Interest, is Now in 29 Countries – Health Policy Watch
Benefits of mRNA COVID vaccines outweigh rare heart risks, says WHO.
12 Jul, 2021 | 03:02h | UTCBenefits of mRNA COVID vaccines outweigh rare heart risks, says WHO – Reuters
See also: EU finds potential link between heart inflammation and mRNA COVID shots – Reuters AND Heart inflammation link to Pfizer and Moderna jabs – BBC
RCT: CoronaVac showed efficacy of 83.5% for preventing symptomatic SARS-CoV-2 infection.
9 Jul, 2021 | 10:22h | UTCInvited commentary: CoronaVac: more data for regulators and policy makers
Commentary on Twitter
NEW—Interim analysis from phase 3 trial suggests efficacy of 2 doses of #CoronaVac is 83.5% against symptomatic #COVID19. More research is needed to confirm efficacy in the long term, in a more diverse group, and against emerging #variants of concern.
? https://t.co/TN5b6wwclc pic.twitter.com/4zOvJFIIOH
— The Lancet (@TheLancet) July 8, 2021
Viewpoint | 7-1-7: an organizing principle, target, and accountability metric to make the world safer from pandemics.
9 Jul, 2021 | 10:21h | UTC
Commentary on Twitter
#COVID19 makes it possible and necessary to review lessons learnt and develop a framework to prepare for future epidemics, writes Thomas Frieden et al.
In this Viewpoint, they propose a 7-1-7 target for outbreak detection, notification, and response: https://t.co/TACjUplpmF pic.twitter.com/4uaxxgxJq2
— The Lancet (@TheLancet) July 7, 2021
Consensus Statement: Guidance for health care leaders during the recovery stage of the COVID-19 pandemic.
9 Jul, 2021 | 10:20h | UTCCommentary: Experts issue pandemic-recovery guidance for health leaders – CIDRAP
Commentary on Twitter
32 experts in healthcare, health leadership, and public health from 17 countries collaborated to create a novel evidence- and expertise-informed framework of leadership imperatives during the recovery stage of the #COVID19 pandemic https://t.co/3gDKZIERBv
— JAMA Network Open (@JAMANetworkOpen) July 8, 2021
Reduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization.
9 Jul, 2021 | 10:16h | UTCReduced sensitivity of SARS-CoV-2 variant Delta to antibody neutralization – Nature
Commentaries: Study highlights need for full Covid vaccination to protect against Delta variant – STAT AND How does the Delta variant dodge the immune system? Scientists find clues. – The New York Times
Commentary on Twitter (thread – click for more)
Just published @Nature
Delta variant protection by mRNA and AZ vaccines requires 2-doses, little neutralizing antibody (nAb) with 1-dose, and insufficient nAb with prior covidhttps://t.co/TOgJdMe0g6 pic.twitter.com/KWLb9rBZ44— Eric Topol (@EricTopol) July 8, 2021
CDC: Use of mRNA COVID-19 vaccine after reports of myocarditis among vaccine recipients – “Continued use of mRNA COVID-19 vaccines in all recommended age groups will prevent morbidity and mortality from COVID-19 that far exceed the number of cases of myocarditis expected”.
9 Jul, 2021 | 10:17h | UTC
Commentary on Twitter
In a new @CDCMMWR, the Advisory Committee on Immunization Practices recommends everyone 12 & older get a #COVID19 vaccine. The benefits of vaccination in preventing illness & death outweigh the rare risk of heart inflammation after vaccination. More: https://t.co/iPjbhU5jeV. pic.twitter.com/IggrZ4DX7L
— CDC (@CDCgov) July 6, 2021
After the pandemic: perspectives on the future trajectory of COVID-19.
9 Jul, 2021 | 10:18h | UTCAfter the pandemic: perspectives on the future trajectory of COVID-19 – Nature
Will COVID become a disease of the young? – “A growing share of infections among unvaccinated youths in countries with high vaccination rates is putting the spotlight on the role of young people in the pandemic”.
9 Jul, 2021 | 10:14h | UTCWill COVID become a disease of the young? – Nature
WHO: Countries urged to reopen with caution as world surpasses four million COVID deaths.
9 Jul, 2021 | 10:12h | UTCSee also: WHO: World at perilous point in pandemic – CIDRAP
Related commentary on Twitter (thread – click for more)
I’m struggling with how best to stress how fragile the global situation is, so I’ll be blunt:
Each week >2.6 million cases and >53,000 deaths are reported to @WHO
Reported, meaning that there are many others.
Stop and think about that.
(Short thread⬇️) pic.twitter.com/OyQK98DkjR
— Maria Van Kerkhove (@mvankerkhove) July 6, 2021
Prospective national cohort in Chile showed CoronaVac effectiveness was 65.9% for symptomatic Covid-19, 87.5% for hospitalization, 90.3% for ICU admission, and 86.3% for death.
8 Jul, 2021 | 09:22h | UTCEffectiveness of an Inactivated SARS-CoV-2 Vaccine in Chile – New England Journal of Medicine
Related: Phase 1/2 RCT: CoronaVac is well tolerated and safe and induces strong humoral responses in children and adolescents aged 3–17 years. AND WHO approval of Chinese CoronaVac COVID vaccine will be crucial to curbing pandemic. AND Brazilian town experiment shows mass vaccination can wipe out COVID-19.
Commentary on Twitter
Chile's data on Sinovac CoronaVac in NEJM: not controlled study. Model details pic 2
– doses 28 days apart (like Serrana trial)
– symptomatic disease 65.9% (65-67)
– hospitalization 87.5% (87-88)
– intensive care 90.3% (89-91)
– Covid death 86.3% (85-88)
https://t.co/CB1U8Ar163 pic.twitter.com/4HwASRCnwQ— Hilda Bastian, PhD (@hildabast) July 7, 2021
Mounting evidence suggests Sputnik COVID vaccine is safe and effective.
8 Jul, 2021 | 09:14h | UTCMounting evidence suggests Sputnik COVID vaccine is safe and effective – Nature
Schooling during COVID-19: Recommendations from the European Technical Advisory Group for schooling during COVID-19.
8 Jul, 2021 | 09:11h | UTC
COVID and schools: the evidence for reopening safely.
8 Jul, 2021 | 09:12h | UTCCOVID and schools: the evidence for reopening safely – Nature