Global & Public Health (all articles) | Page 42 of 252 | Links Medicus Content Curation & Alerts in Medicine

Vaccine apartheid: This is not the way to end the pandemic.

22 Oct, 2021 | 10:26h | UTC

Vaccine apartheid: This is not the way to end the pandemic – Journal of Paediatrics and Child Health

Commentary on Twitter

Vaccine apartheid is devastating, especially for children@VSLanziotti @yoncabulutmd @surf4children @sgdambrauskas call for everyone to advocate for vaccine equity https://t.co/jzJd9kwcCi pic.twitter.com/0hEPk8B4xv

— Madhu Pai, MD, PhD (@paimadhu) October 21, 2021

Opinion | Politics is derailing a crucial debate over the immunity you get from recovering from Covid-19.

22 Oct, 2021 | 10:22h | UTC

Covid-19 Politics is derailing a crucial debate over the immunity you get from recovering from Covid-19 – STAT

Cluster RCT: Increasing the dietary sources of calcium and protein (by providing additional milk, yogurt, and cheese) reduced hip fractures and falls in older adults in residential care.

22 Oct, 2021 | 10:21h | UTC

Effect of dietary sources of calcium and protein on hip fractures and falls in older adults in residential care: cluster randomised controlled trial – The BMJ

News release: Increasing dairy intake reduces falls and fractures among older care home residents – British Medical Journal

Commentary on Twitter

Increasing intake of foods rich in calcium and protein such as milk, yoghurt, and cheese, reduces falls and fractures in older adults living in residential care, finds a randomised controlled trial published @bmj_latest today https://t.co/QzozG4Odjb

— BMJ Group (@bmj_company) October 21, 2021

Health care–acquired infections in low- and middle-income countries and the role of infection prevention and control.

22 Oct, 2021 | 10:09h | UTC

Health Care–Acquired Infections in Low- and Middle-Income Countries and the Role of Infection Prevention and Control – Infectious Disease Clinics of North America

An analysis of Scotland’s mortality in 114,000 SARS-CoV2–infected people revealed that the vaccine effectiveness against death from the Delta variant was 90% for the Pfizer vaccine and 91% for AstraZeneca.

21 Oct, 2021 | 10:15h | UTC

BNT162b2 and ChAdOx1 nCoV-19 Vaccine Effectiveness against Death from the Delta Variant – New England Journal of Medicine

Pfizer vaccine showed estimated effectiveness of 93% against symptomatic SARS-CoV-2 Delta variant infection in adolescents.

21 Oct, 2021 | 10:17h | UTC

Effectiveness of BNT162b2 Vaccine against Delta Variant in Adolescents – New England Journal of Medicine

Commentary on Twitter

The remarkably high effectiveness (VE) of vaccination for teens vs the Delta variant in over 94,000 vaccinees and 94,000 matched controls: 93% VE vs symptomatic infection (95% CI 88,97) https://t.co/wwoXlw7PH9 @NEJM pic.twitter.com/8m3fJ7avc5

— Eric Topol (@EricTopol) October 20, 2021

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

21 Oct, 2021 | 10:14h | UTC

Covid-19 Vaccination during Pregnancy and First-Trimester Miscarriage – New England Journal of Medicine

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

FDA authorizes booster doses of Moderna and Johnson & Johnson vaccines, says mix and match OK.

21 Oct, 2021 | 10:09h | UTC

FDA authorizes booster doses of Moderna and Johnson & Johnson vaccines, says mix and match OK – CNN

Instead of quarantine for Covid-exposed students, some schools are trying test-to-stay.

21 Oct, 2021 | 10:08h | UTC

Instead of quarantine for Covid-exposed students, some schools are trying test-to-stay – CNN

Cluster RCT: Daily contact testing of school-based contacts was non-inferior to self-isolation for control of COVID-19 transmission.

Kids are losing school days to quarantines. Here’s a way to keep them in classrooms – “Test-to-stay could dramatically reduce close contact quarantines”.

Opinion | Data from routine Covid testing can help schools stay open this year.

CDC Study: Pfizer vaccine showed 93% effectiveness against Covid-19 hospitalization among children aged 12-18 years.

20 Oct, 2021 | 10:31h | UTC

Effectiveness of Pfizer-BioNTech mRNA Vaccination Against COVID-19 Hospitalization Among Persons Aged 12–18 Years — United States, June–September 2021 – CDC Morbidity and Mortality Weekly Report

Commentary on Twitter (thread – click for more)

Vaccination reduced the risk of hospitalization among 12–18-year-olds by 93%, according to a new CDC study. No vaccinated adolescents died or were admitted to the ICU.

— Dr. Tom Frieden (@DrTomFrieden) October 19, 2021

Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden.

20 Oct, 2021 | 10:27h | UTC

Effectiveness of heterologous ChAdOx1 nCoV-19 and mRNA prime-boost vaccination against symptomatic Covid-19 infection in Sweden: A nationwide cohort study – The Lancet Regional Health Europe

Commentary: High effectiveness of mix-and-match COVID-19 vaccines – UMEA University

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

Commentary on Twitter

Study from Sweden assessing heterogenous vaccination in 3,445,061 individuals who received AZ as the first dose and either #pfizer, #moderna, or #AZ as second dose showed the following vaccine effectiveness:

AZ/Pfizer- 67%
AZ/Moderna- 79%
AZ/AZ- 50%https://t.co/UN0pey2kJ2

— Yan Leyfman, MD (@YLeyfman) October 19, 2021

Should You Mix and Match Your Booster Shot?

20 Oct, 2021 | 10:25h | UTC

Should You Mix and Match Your Booster Shot? – The Atlantic

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

[Preprint] Observational study in Brazil showed the J&J vaccine adjusted effectiveness was 50.9% against any symptomatic Covid-19, 72.9% for hospitalization, 92.5% for ICU admission, 88.7% for mechanical ventilation, and 90.5% for death.

20 Oct, 2021 | 10:24h | UTC

Vaccine effectiveness of Ad26.COV2.S against symptomatic COVID-19 and clinical outcomes in Brazil: a test-negative study design – medRxiv

WHO Policy Brief: The urgent need to implement patient blood management.

20 Oct, 2021 | 10:15h | UTC

The urgent need to implement patient blood management: policy brief – World Health Organization

Covid-19: New mutation of Delta variant under close watch in UK.

20 Oct, 2021 | 10:21h | UTC

Covid-19: New mutation of Delta variant under close watch in UK – BBC

WHO’s 7 policy recommendations on building resilient health systems.

20 Oct, 2021 | 10:18h | UTC

News release: WHO’s 7 policy recommendations on building resilient health systems – World Health Organization

WHO Position Paper: Building health systems resilience for universal health coverage and health security during the COVID-19 pandemic and beyond

Commentary on Twitter (thread – click for more)

#COVID19 has shown that there can be no lasting economic development without #HealthForAll & protection against health emergencies. Here are WHO’s 7⃣ recommendations on building resilient health systems based on #PrimaryHealthCare & #HealthSecurity.

👉 https://t.co/pp5Gh9BTnz pic.twitter.com/0d021b5ylf

— World Health Organization (WHO) (@WHO) October 19, 2021

China’s COVID vaccines have been crucial — now immunity is waning.

19 Oct, 2021 | 09:53h | UTC

China’s COVID vaccines have been crucial — now immunity is waning – Nature

[Preprint] Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 – “Vaccine protection declined by mid-August 2021, decreasing from 91.9% in March to 53.9%”.

Observational study in Qatar showed the effectiveness of Pfizer vaccine against any SARS-CoV-2 infection dropped to 20% in months 5 through 7 after the second dose, but effectiveness against severe Covid-19 remained high.

Cohort study: Pfizer vaccine effectiveness against any infections declined from 88% during the first month after full vaccination to 47% after 5 months. Vaccine effectiveness against hospital admissions remained high; 87% within 1 month, and 88% at 5 months after full vaccination, with no significant waning.

Editorial | Covid-19 vaccination: evidence of waning immunity is overstated.

COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.

COVID vaccine effects wane over time but still prevent death and severe illness.

Perspective | What we actually know about waning immunity.

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.

Studies: COVID vaccine protection waning against infection but not hospitalization.

Systematic Review: Restricting access to poisons is associated with decreases in suicide by poisoning without an equivalent shift toward other methods.

20 Oct, 2021 | 09:48h | UTC

Association Between Means Restriction of Poison and Method-Specific Suicide Rates: A Systematic Review – JAMA Network Open

Commentary on Twitter

Important new study on suicide in @JAMAHealthForum. Restricting access to poisons is associated with reductions in suicide without an equivalent shift toward other methods. https://t.co/dINq3oIxvd pic.twitter.com/vEn9wOlprN

— David Juurlink (@DavidJuurlink) October 18, 2021

BJS commission on surgery and perioperative care post-COVID-19.

19 Oct, 2021 | 09:52h | UTC

BJS commission on surgery and perioperative care post-COVID-19 – British Journal of Surgery

Commentary on Twitter

The @BJSurgery commission on surgery and perioperative care post #Covid_19

🌐 Global surgical community involved

😱 Pandemic uncovers problems in healthcare systems

🧑‍🎓 Training severely damaged

🧿 Ethics committee needed at surgical oncology centreshttps://t.co/CfNk9vBPjV pic.twitter.com/vomtZ3zcql

— Giovanni Marchegiani (@Gio_Marchegiani) October 16, 2021

Editorial: Preparing for “Disease X”.

19 Oct, 2021 | 09:54h | UTC

Preparing for “Disease X” – Science

Cluster RCT: An exercise intervention may improve academic achievement among children.

19 Oct, 2021 | 09:45h | UTC

Exercise Intervention for Academic Achievement Among Children: A Randomized Controlled Trial – Pediatrics

Commentary on Twitter

Physical inactivity is an important health concern worldwide. This study examined the effects of an exercise intervention on children’s academic achievement, cognitive function, physical fitness, and other health-related outcomes: https://t.co/Pdd0qZqYNN #Pediatrics pic.twitter.com/VkyPba3Sv2

— AAP CME Journals (@AAPJournals) October 18, 2021

J&J COVID-19 Vaccine: FDA recommends booster shot for all adults aged 18 and older at least two months following initial vaccination with the single-shot vaccine.

17 Oct, 2021 | 21:32h | UTC

News release: Johnson & Johnson COVID-19 Vaccine Booster Shot Unanimously Recommended for Emergency Use Authorization by U.S. FDA Advisory Committee

Commentaries:

FDA panel endorses booster shot for J&J COVID-19 vaccine – Associated Press

The Johnson & Johnson one-dose vaccine offers good protection now. A booster shot will maximize that, experts say – CNN

FDA advisers recommend J&J Covid-19 vaccine boosters, talk mix and match boosters – CNN

[Preprint] Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 – “Vaccine protection declined by mid-August 2021, decreasing from 91.9% in March to 53.9%”.

17 Oct, 2021 | 21:29h | UTC

Breakthrough SARS-CoV-2 infections in 620,000 U.S. Veterans, February 1, 2021 to August 13, 2021 – medRxiv

Editorial | Covid-19 vaccination: evidence of waning immunity is overstated.

COVID vaccine immunity is waning — how much does that matter? – “As debates about booster shots heat up, what’s known about the duration of vaccine-based immunity is still evolving”.

COVID vaccine effects wane over time but still prevent death and severe illness.

Perspective | What we actually know about waning immunity.

Another study shows Pfizer mRNA vaccine immunity is reduced over time.

[Press release – not published yet] Study shows vaccine protection wanes over time, but vaccines still offer good protection against severe disease.

Studies: COVID vaccine protection waning against infection but not hospitalization.

Commentary on Twitter

New on breakthrough infections in 620,000 Veterans
"Vaccine protection declined by mid-August 2021, decreasing from 91.9% in March to 53.9%"https://t.co/xonBb4aEqJ highest reduction with J&J vaccine pic.twitter.com/rbhXOREFPP

— Eric Topol (@EricTopol) October 15, 2021