Open access
Open access
Powered by Google Translator Translator

Global & Public Health (all articles)

Under-reporting of deaths limits our understanding of true burden of covid-19.

29 Oct, 2021 | 10:18h | UTC

Under-reporting of deaths limits our understanding of true burden of covid-19 – The BMJ

Related:

Study shows COVID-19 has caused the biggest decrease in life expectancy since World War II.

Just how do deaths due to COVID-19 stack up?

Tracking excess mortality across countries during the COVID-19 pandemic with the World Mortality Dataset.

Exploring the gap between excess mortality and COVID-19 deaths in 67 countries.

Report: Three new estimates of India’s all-cause excess mortality during the COVID-19 Pandemic – pandemic death toll estimated to be between 3.4 million and 4.9 million excess deaths.

COVID-19 has caused 6.9 million deaths globally, more than double what official reports show

 

Commentary on Twitter

 


mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern.

29 Oct, 2021 | 10:16h | UTC

mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern – Science

 

Commentary from the author on Twitter (thread – click for more)

 


Nine Pandemic Words That Almost No One Gets Right.

29 Oct, 2021 | 10:12h | UTC

Nine Pandemic Words That Almost No One Gets Right – The Atlantic

 


WHO Guideline for clinical management of exposure to lead.

29 Oct, 2021 | 09:56h | UTC

Guideline for clinical management of exposure to lead – World Health Organization

Executive Summary: Guideline for clinical management of exposure to lead

See also: International Lead Poisoning Prevention Week 2021

 

Commentary on Twitter (thread – click for more)

 


Merck to allow other nations to produce new COVID-19 antiviral.

28 Oct, 2021 | 10:18h | UTC

Merck to allow other nations to produce new COVID-19 antiviral – CIDRAP

See also:

Merck will allow drugmakers in other countries to make its COVID-19 pill – NPR

Game-Changing COVID-19 Oral Treatment Set To Become Widely Accessible in Low- and Middle-Income Countries Upon Regulatory Approval – Health Policy Watch

Related:

Video: Merck’s Covid pill could transform treatment. Here’s how it works.

How antiviral pill Molnupiravir shot ahead in the COVID drug hunt.

What we know — and don’t know — about Merck’s new Covid-19 pill.

[Press release – not published yet] Merck announces oral antiviral Molnupiravir reduced the risk of hospitalization or death by approximately 50 Percent compared to placebo for patients with mild or moderate COVID-19.

Merck’s Covid-19 pill is great news but may not be a game-changer.

Video | A Pill For COVID? A Doctor Explains Molnupiravir.

 


Two observational studies cast doubt on the effects of school closures to reduce the spread of Covid-19.

28 Oct, 2021 | 10:17h | UTC

Study 1: No causal effect of school closures in Japan on the spread of COVID-19 in spring 2020 – Nature Medicine

Study 2: The impact of school opening model on SARS-CoV-2 community incidence and mortality – Nature Medicine

 

Commentaries on Twitter

(thread – click for more)

 


What COVID vaccines for young kids could mean for the pandemic.

28 Oct, 2021 | 10:15h | UTC

What COVID vaccines for young kids could mean for the pandemic – Nature

Related: FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children ages 5 to 11.

 


Breakthrough infections occur in those with lower antibody levels.

27 Oct, 2021 | 01:45h | UTC

Breakthrough Infections Occur in Those with Lower Antibody Levels, Israeli Study Shows – NIH Director’s Blog

Original study: Covid-19 Breakthrough Infections in Vaccinated Health Care Workers – New England Journal of Medicine

 


FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children ages 5 to 11.

27 Oct, 2021 | 01:48h | UTC

FDA advisory panel recommends Pfizer Covid-19 vaccine be authorized for children – STAT

See also:

Tracking the FDA advisory panel meeting on Covid-19 vaccines for kids – STAT

FDA advisory panel recommends Pfizer vaccine for kids ages 5 to 11 – NPR

 


Mix-and-match COVID vaccines ace the effectiveness test – “No need for brand loyalty”.

27 Oct, 2021 | 01:42h | UTC

Mix-and-match COVID vaccines ace the effectiveness test – Nature

Related:

Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden.

Should You Mix and Match Your Booster Shot?

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 


Heterologous AstraZeneca/Pfizer vaccination seems to be associated with increased effectiveness against Covid-19 compared to homologous Pfizer/Pfizer vaccination.

27 Oct, 2021 | 01:44h | UTC

Immunogenicity and efficacy of heterologous ChadOx1/BNT162b2 vaccination – Nature

Related:

Cohort Study: The effectiveness of heterologous AstraZeneca (AZ)/mRNA prime-boost vaccination was more significant (68%) compared to the effectiveness of homologous AZ/AZ vaccination (50%) against symptomatic Covid-19 infection in Sweden.

Should You Mix and Match Your Booster Shot?

Study evaluated several heterologous SARS-CoV-2 vaccine regimens; no efficacy data but there was increased antibody production on study days 15 and 29 after booster shots from Moderna and Pfizer.

A primer on what we know about mixing and matching Covid vaccines.

Real-world data shows increased reactogenicity in adults after heterologous compared to homologous prime-boost COVID-19 vaccination.

RCT: Safety and immunogenicity of heterologous vs. homologous prime-boost schedules with an adenoviral vectored and mRNA COVID-19 vaccine.

Another study shows increased immune response with heterologous Oxford-AstraZeneca/mRNA vaccination.

Heterologous Oxford–AstraZeneca and Moderna Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

Heterologous Oxford–AstraZeneca and BioNTech/Pfizer Vaccination induce increased levels of neutralizing antibody compared to 2 doses of Oxford–AstraZeneca.

[Preprint] Mixing Covid jabs has good immune response, study finds – “The Com-Cov trial looked at the efficacy of either two doses of Pfizer, two of AstraZeneca, or one of them followed by the other. All combinations worked well, priming the immune system”.

Phase 2 RCT: Immunogenicity and reactogenicity of a Pfizer-BioNTech booster in patients that have received a single dose of AstraZeneca vaccine – “BNT162b2 (Pfizer) given as a second dose in individuals prime vaccinated with ChAdOx1-S (AstraZeneca) induced a robust immune response, with an acceptable and manageable reactogenicity profile”.

Lab study shows heterologous AstraZeneca/Pfizer vaccination produces strong immune response against SARS-CoV-2 Delta variant.

Lab study shows a heterologous AstraZeneca + Pfizer immunization strategy provides stronger immunogenicity against Covid compared to homologous AZ + AZ or Pfizer + Pfizer strategies.

RCT: Mixing 2 different Covid vaccines is associated with increased risk of side effects.

 

Commentary on Twitter

 


What game theory can teach us about controlling pandemics.

27 Oct, 2021 | 01:39h | UTC

What game theory can teach us about controlling pandemics – The BMJ Opinion

 

Commentary on Twitter

https://twitter.com/glassmanamanda/status/1451498564044136450

 


[Press release – not published yet] Moderna says its COVID vaccine produced a strong antibody response for kids 6 to 11.

26 Oct, 2021 | 02:06h | UTC

Press release: Moderna Announces Positive Top Line Data from Phase 2/3 Study of COVID-19 Vaccine in Children 6 to 11 Years of Age

Commentary: Moderna says new data supports its COVID vaccine for kids 6 to 11 – NPR

 


Infection with Covid-19 carries a much higher risk of developing neurological complications than Covid-19 vaccines.

26 Oct, 2021 | 02:04h | UTC

News Release: Infection with Covid-19 carries a much higher risk of developing neurological complications than a vaccine, says new study – University of Nottingham

Original Study: Neurological complications after first dose of COVID-19 vaccines and SARS-CoV-2 infection – Nature Medicine

Commentaries:

Covid: Vaccine study links virus to rare neurological illness – BBC

Expert reaction to study looking at rare neurological complications after SARS-CoV-2 infection and COVID-19 vaccination – Science Media Centre

 

Commentary on Twitter

 


COVID: how worried should we be about the new AY.4.2 lineage of the coronavirus?

26 Oct, 2021 | 02:01h | UTC

COVID: how worried should we be about the new AY.4.2 lineage of the coronavirus? – The Conversation

 


What It Means To Be Fully Vaccinated.

26 Oct, 2021 | 01:57h | UTC

What It Means To Be Fully Vaccinated – Think Global Health

 


Association of a sweetened beverage tax with reduction in soda consumption in high school students.

26 Oct, 2021 | 01:30h | UTC

Association of a Sweetened Beverage Tax With Soda Consumption in High School Students – JAMA Pediatrics (free for a limited period)

Commentary: Philadelphia’s ‘soda tax’ cut the number of sugar-sweetened beverages high school students drank per week by 30%, study finds – News Break

Related:

Changes in food purchases after the Chilean policies on food labelling, marketing, and sales in schools: a before and after study.

UK National Food Strategy: Tax sugar and salt and prescribe veg, report says.

Perspective – Sugar-sweetened beverage taxes: Lessons to date and the future of taxation

Cohort Study: Association Between Tax on Sugar Sweetened Beverages and Soft Drink Consumption

Meta-Analysis: Impact of Sugar‐sweetened Beverage Taxes on Purchases and Dietary Intake

Cochrane Review: Environmental Interventions to Reduce the Consumption of Sugar‐sweetened Beverages and Their Effects on Health

Study: Snack Tax May be More Effective than a Sugary Drink Tax to Tackle Obesity

Sugar Tax: Why Health Experts Want it But Politicians and Industry are Resisting

The Effect of Food Price Changes on Consumer Purchases: A Randomized Experiment

Taxes on Sugar-Sweetened Beverages Associated with Reduced Consumption

Soda Tax Linked to a 50 Percent Reduction in Sugary Drink Consumption

AAP/AHA Policy Statement: Public Policies to Reduce Sugary Drink Consumption in Children and Adolescents

Fiscal policies for diet and the prevention of noncommunicable diseases – World Health Organization

The Lancet taskforce on NCDs and economics

To improve global health, tax the things that are killing us – Financial Times

Reducing cardiovascular disease burden through targeted dietary policies

Fiscal policies for the prevention of diseases

The potential impact of food taxes and subsidies on cardiovascular disease and diabetes burden and disparities

 

Commentary on Twitter

 


Half doses, third doses, kids’ doses: Covid vaccine delivery goes next-level difficult.

24 Oct, 2021 | 23:52h | UTC

Half doses, third doses, kids’ doses: Covid vaccine delivery goes next-level difficult – STAT

 


How you’ll know when Covid-19 has gone from “pandemic” to “endemic”.

24 Oct, 2021 | 23:53h | UTC

How you’ll know when Covid-19 has gone from “pandemic” to “endemic” – Vox

 


AstraZeneca vaccination not linked to reduced fertility rates and adverse birth outcomes.

24 Oct, 2021 | 23:58h | UTC

Fertility rates and birth outcomes after ChAdOx1 nCoV-19 (AZD1222) vaccination – The Lancet

Related:

A case-controlled study showed Covid-19 vaccination during early pregnancy was not associated with increased risk of first-trimester miscarriage.

Editorial: Covid-19 treatments and vaccines must be evaluated in pregnancy.

Cohort study: Vaccinated pregnant patients had 90% lower risk of severe or critical Covid-19 compared with unvaccinated pregnant patients.

Two observational studies suggest spontaneous abortion is not increased following COVID-19 mRNA vaccination during pregnancy.

Study shows high effectiveness of the Pfizer mRNA COVID-19 vaccine in pregnancy.

5 Crucial Things to Know About COVID-19 Vaccines and Pregnancy.

CDC Guidance: Pregnant people should be vaccinated against COVID-19.

ACOG and SMFM Recommend COVID-19 Vaccination for Pregnant Individuals – “ACOG encourages its members to enthusiastically recommend vaccination to their patients.”

Cohort study: Pfizer/BioNTech COVID vaccine associated with 78% lower risk of Covid-19 in pregnancy.

 

Commentary on Twitter

 


Coronavirus: Chinese residents start receiving vaccine boosters.

24 Oct, 2021 | 23:51h | UTC

Coronavirus: Chinese residents start receiving vaccine boosters – South China Morning Post

 


Corporate influence linked to slow implementation of public health policies globally.

24 Oct, 2021 | 23:37h | UTC

Implementation of non-communicable disease policies from 2015 to 2020: a geopolitical analysis of 194 countries – The Lancet Global Health

News Release: Corporate influence linked to slow implementation of public health policies globally – London School of Hygiene & Tropical Medicine

 

Commentary on Twitter (thread – click for more)

 


Extreme heat is broiling people in developing cities: New analysis finds the explosive growth of cities is helping drive dangerous conditions.

24 Oct, 2021 | 23:34h | UTC

Extreme heat is broiling people in developing cities – Science

Original Study: Global urban population exposure to extreme heat – Proceedings of the National Academy of Sciences

 

Commentary on Twitter

 


[Press release – not published yet] A phase 3 trial with more than 10,000 participants showed a booster dose of the Pfizer/BioNTech vaccine had an efficacy of 95.6% against disease; there were 5 cases in the booster group and 109 cases in the non-boosted group, not classified according to severity.

22 Oct, 2021 | 10:34h | UTC

Pfizer and BioNTech Announce Phase 3 Trial Data Showing High Efficacy of a Booster Dose of Their COVID-19 Vaccine

Commentary: Booster dose of Pfizer/BioNTech coronavirus vaccine shows 95.6% efficacy in Phase 3 trial, companies say – CNN

 

Commentaries on Twitter

 


WHO estimates that between 80 000 to 180 000 health and care workers could have died from Covid-19.

22 Oct, 2021 | 10:29h | UTC

News release: WHO and partners call for action to better protect health and care workers from COVID-19 – World Health Organization

WHO Statement: joint statement on WHO’s estimates of health and care worker deaths due to covid-19

Report: The impact of COVID-19 on health and care workers: a closer look at deaths – World Health Organization

Commentaries:

WHO calls for health worker protection against COVID-19 – CIDRAP

WHO estimate: 115,000 health workers have died from Covid-19, as calls for vaccine access grow – STAT

Covid may have killed up to 180,000 health workers globally, WHO says – The Guardian

 

Commentary on Twitter

 


Stay Updated in Your Specialty

Telegram Channels
Free

WhatsApp alerts 10-day free trial

No spam, just news.