Global & Public Health (all articles)
Estimation of US children’s educational attainment and years of life lost associated with primary school closures during the Covid-19 pandemic
18 Nov, 2020 | 09:15h | UTC
[Preprint] Study suggests immunity to the Coronavirus may last years
18 Nov, 2020 | 09:20h | UTCImmunological memory to SARS-CoV-2 assessed for greater than six months after infection – bioRxiv
Commentaries: Immunity to the Coronavirus May Last Years, New Data Hint – New York Times AND Could coronavirus immunity last YEARS? Study finds even survivors who had mild COVID-19 are protected for at least 8 months and their immune ‘memory’ may last MUCH longer – Daily Mail AND COVID-19: Study Suggests Durable Immune Response After SARS-CoV-2 Infection – NEJM Journal Watch
Commentary from the author on Twitter (thread – click for more)
1/ Our pre-print on immune memory to SARS-CoV-2 is out today. To our knowledge, this is the largest such study for any acute infection.
The upshot is that there is substantial immune memory after COVID-19.
Lots of stuff in this manuscript.https://t.co/lSAyZp0XiK@SetteLab
— Shane Crotty (@profshanecrotty) November 17, 2020
Opinion: A new important study supports wider use of the polypill
18 Nov, 2020 | 09:01h | UTCRichard Smith: A new important study supports wider use of the polypill – The Lancet
Original study and commentaries: Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk
Commentary on Twitter
"We seem now to have good evidence that the polypill can reduce cardiovascular events and deaths by at least a third and probably by half in those who take the polypill regularly" @Richard56 discusses a new study in @NEJM https://t.co/B2tkN4pkDP
— The BMJ (@bmj_latest) November 17, 2020
Surveillance of wastewater revealed peaks of SARS-CoV-2 preceding those of hospitalized patients with COVID-19
17 Nov, 2020 | 09:53h | UTC
CDC Report: Multiple COVID-19 outbreaks linked to a wedding reception
17 Nov, 2020 | 09:51h | UTCCommentaries: CDC: One wedding led to 177 cases of COVID-19 and 7 deaths because attendees refused to wear masks and physically distance – Business Insider AND Maine wedding outbreak offers a cautionary Covid-19 tale for the holidays – CNN AND Maine Wedding Gives Half Of The Guests Coronavirus, Outbreak Leads To 177 Covid-19 Cases And 7 Deaths – Forbes
[Press release – not published yet] Moderna’s COVID-19 vaccine candidate shows 94.5% protection in an interim analysis of the phase 3 COVE study
17 Nov, 2020 | 09:55h | UTCPress release: Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study
See also: Moderna Announces Longer Shelf Life for its COVID-19 Vaccine Candidate at Refrigerated Temperatures
Commentaries: What Moderna’s Covid-19 vaccine results mean for ending the pandemic – Vox AND Moderna follows Pfizer with exciting vaccine news – how to read these dramatic developments – The Conversation AND Moderna’s COVID Vaccine Is 95% Effective – Independent NIH-Appointed Board Assessment – Higher Storage Temperature Make It Even Better News – Health Policy Watch AND Moderna’s Vaccine News “Encouraging” But Won’t Solve Immediate Problem of Virus Surge in Europe & Americas – WHO – Health Policy Watch AND COVID vaccine excitement builds as Moderna reports third positive result – Nature AND Moderna’s Covid-19 vaccine is strongly effective, early look at data show – STAT AND With strong data on two Covid-19 vaccines, we have more answers about the road ahead — and questions too – STAT AND Early data show Moderna’s COVID vaccine 94.5% effective – CIDRAP AND A Note Of Caution On Moderna’s Promising Covid-19 Vaccine News – Forbes AND Promising Interim Results from Clinical Trial of NIH-Moderna COVID-19 Vaccine – NIH News Releases AND Moderna: Covid vaccine shows nearly 95% protection – BBC AND Latest vaccine success is good news but high price may restrict access – The Guardian AND ‘Just beautiful’—Another COVID-19 vaccine, from newcomer Moderna, succeeds in large-scale trial – Science AND Moderna trial success gives world more hope in race to end pandemic – Reuters AND Expert reaction to Moderna announcement of its phase 3 vaccine interim results – Science Media Centre
CDC Report: Mental health-related emergency department visits among children aged under 18 years raised during the COVID-19 Pandemic
17 Nov, 2020 | 09:48h | UTCCommentary: ER Data Indicates the Pandemic Is Harming Children’s Mental Health – U.S. News
Commentary on Twitter
New @CDCMMWR suggests that the #COVID19 pandemic may be negatively impacting children’s mental health. The proportion of emergency room visits for mental health concerns in children & adolescents increased substantially this past Mar.-Oct. Read the report: https://t.co/9FyLoCzrza pic.twitter.com/fIXMIZg7KK
— CDC (@CDCgov) November 12, 2020
CDC Report: 9% readmitted after Covid-19 hospitalization. Risk factors were age ≥65 y, chronic medical conditions, recent hospitalization before Covid-19, and discharge to a skilled nursing facility or with home health care
17 Nov, 2020 | 09:46h | UTCCommentary: 9 percent readmitted after index COVID-19 hospitalization – MedicalXpress AND One in 11 coronavirus patients discharged from a hospital is readmitted within two months, suggesting long-lasting effects of the infection, CDC report warns – Daily Mail
Commentary on Twitter
A new @CDCMMWR finds 9% of the more than 100,000 patients discharged after being hospitalized for #COVID19 were readmitted to the same hospital within 2 months. Learn more: https://t.co/s96NXLxQUE. pic.twitter.com/ugJq9f1gHP
— CDC (@CDCgov) November 9, 2020
The Great Coronavirus Pandemic of 2020—7 Critical Lessons
17 Nov, 2020 | 09:42h | UTCThe Great Coronavirus Pandemic of 2020—7 Critical Lessons – JAMA
Commentary on Twitter
1. Build Resilient Health Systems
2. Leadership and Public Trust Matter
3. Science and Public Health Matters
4. Biomedical Research and Development Matters
5. Equity Matters
6. Evidence-Based Law Matters
7. Global Institutions Matter https://t.co/czxGwyAGCn @LawrenceGostin— JAMA (@JAMA_current) November 16, 2020
Primary care guidance for persons with HIV: 2020 update by the HIV Medicine Association of the Infectious Diseases Society of America
17 Nov, 2020 | 09:36h | UTCNews Release: IDSA and HIVMA Release New Comprehensive Primary Care Guidance for People with HIV – Infectious Diseases Society of America
Worldwide measles deaths climb 50% from 2016 to 2019, claiming over 207 500 lives in 2019
17 Nov, 2020 | 09:34h | UTCSee also: Action needed now to prevent further increases in measles and measles deaths in the coming years – The Lancet AND Progress Toward Regional Measles Elimination — Worldwide, 2000–2019 – CDC Morbidity and Mortality Weekly Report
Commentary on Twitter
NEW—Action needed now to prevent further increases in #measles and measles deaths in the coming years
Kim Mulholland, Katrina Kretsinger, Liya Wondwossen & Natasha Crowcroft lay out three pillars of action needed to address this concerning situation https://t.co/m6nD6yupMp pic.twitter.com/njd5PD9K3s
— The Lancet (@TheLancet) November 13, 2020
#AHA20 – Randomized trial: A polypill comprising statins, multiple blood pressure lowering drugs, and aspirin prevents cardiovascular events among patients at intermediate cardiovascular risk
16 Nov, 2020 | 02:03h | UTCPolypill with or without Aspirin in Persons without Cardiovascular Disease – New England Journal of Medicine (link to abstract – $ for full-text)
News release: New study confirms combo pill alone and with aspirin lowers heart disease risk – American Heart Association
Commentaries: Polypill along with aspirin cuts heart attacks and strokes by up to 40%: International study – McMaster University AND Big study supports cheap combo pill to lower heart risks – Associated Press AND TIPS-3: International Study Looks at Benefits of Polypill and Polypill Plus Aspirin in Reducing CVD Risk – American College of Cardiology
Commentary on Twitter
Public health vs precision medicine. Thinking through a one size fits all drug prevention approach. "Combined Rx w/polypill+aspirin led to lower incidence of CV events than placebo among participants w/o CV disease who were at intermediate CV risk.” #AHA20https://t.co/TsbvPtA1Pl pic.twitter.com/Ylq3AKThII
— Harlan Krumholz (@hmkyale) November 14, 2020
Practice Pointer: Using antibiotics wisely for respiratory tract infection in the era of covid-19
16 Nov, 2020 | 01:48h | UTCUsing antibiotics wisely for respiratory tract infection in the era of covid-19 – The BMJ
Commentary on Twitter
When should patients with respiratory tract infections be assessed in person and when should you prescribe antibiotics based on best available evidence? This Practice Pointer offers guidance in the era of covid-19https://t.co/k6LoYPWmsv pic.twitter.com/rtIrjplyv0
— The BMJ (@bmj_latest) November 15, 2020
Sweden has admitted its coronavirus immunity predictions were wrong as cases soar across the country
16 Nov, 2020 | 01:44h | UTC
Perspective: The third surge is breaking health-care workers
16 Nov, 2020 | 01:46h | UTC
Commentary from the author (thread – click for more)
?I wrote about what health-care workers are going through, how exhausted & scared they are, and what this 3rd pandemic surge is doing to them.
It’s not like the first 2. It’s worse. How much slack is left in the system? Iowa nurse: “There is none” 1/ https://t.co/is2NGHdwRP
— Ed Yong (@edyong209) November 13, 2020
World Diabetes Day 2020 (14 November 2020): Introducing the Global Diabetes Compact
16 Nov, 2020 | 01:43h | UTCWorld Diabetes Day 2020: Introducing the Global Diabetes Compact – World Health Organization
See also: WHO Global Diabetes Compact
Related: The Lancet Commission on diabetes: using data to transform diabetes care and patient lives (free registration required) AND Editorial: Turning evidence into action on diabetes – The Lancet
Commentary on Twitter (thread – click for more)
It's #WorldDiabetesDay #COVID19 causes fear & suffering for people with #diabetes:
1⃣ They have ↗️ risk of severe disease & death when infected with COVID-19
2⃣ Delay in diagnosis may result in more advanced disease & complications
3⃣ Delayed, incomplete, interrupted treatment pic.twitter.com/vlL9XAXVqq— World Health Organization (WHO) (@WHO) November 14, 2020
Long Covid: Persistent fatigue following SARS-CoV-2 infection is common and independent of severity of initial infection
13 Nov, 2020 | 09:27h | UTCCommentary: Half of recovered COVID-19 patients report lingering fatigue – CIDRAP
Long Covid: 2 months after being hospitalized for Covid-19, many patients persisted symptomatic and did not resume normal activities
13 Nov, 2020 | 09:28h | UTCSixty-Day Outcomes Among Patients Hospitalized With COVID-19 – Annals of Internal Medicine
Commentary on Twitter
New Mich. hospital data: Of people admitted with COVID, 70% were alive and home 60 days later.
Of those who'd been working, 40% either lost their job or were still too sick to work.
It's not just the deaths; it's the health and economic damage. https://t.co/wMGkJw5KSF pic.twitter.com/8EbHktTxRX
— Atul Gawande (@Atul_Gawande) November 12, 2020
How risky is air travel in the pandemic? Here’s what the science says
13 Nov, 2020 | 09:22h | UTCHow risky is air travel in the pandemic? Here’s what the science says – Vox
Perspective: Many younger adults need to take Covid-19 more seriously as demographics shift
13 Nov, 2020 | 09:25h | UTCYounger Adults Caught in COVID-19 Crosshairs as Demographics Shift – JAMA
Commentary from the author on Twitter (thread – click for more)
?For healthy young and middle-aged adults, focusing on the lower hospitalization, death risk misses the point. Even "mild" #COVID19 can be life-altering. My latest for @JAMA_current https://t.co/vV29SlYz5u 1/
— jenabbasi (@jenabbasi) November 12, 2020
Review for the public on the different kinds of COVID-19 tests. It covers the differences and similarities between molecular, antigen, and serologic tests.
12 Nov, 2020 | 09:19h | UTC
Why do COVID death rates seem to be falling? Correct use of corticosteroids, hard-won experience, younger patients, and reduced strain on hospitals are all possibilities
12 Nov, 2020 | 09:16h | UTCWhy do COVID death rates seem to be falling? – Nature
[Preprint] Validation of home oxygen saturation as a marker of clinical deterioration in patients with suspected COVID-19: Even small deflections in oxygen saturations of 1-2% below 96% confer an increased mortality risk.
12 Nov, 2020 | 09:18h | UTC
Commentary on Twitter
*BREAKING* First paper examining home oxygen saturation in COVID confirmed cases as a trigger for initial hospital assessment. We need to rapidly implement a hybrid community-hospital COVID Oximetry@home #COVIDvirtualward @richardhorton1 @bmj_latest https://t.co/0SjrUT0Tjw pic.twitter.com/0TgPPRUBqv
— Matt Inada-Kim (@mattinadakim) November 8, 2020
Opinion: “Why the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism. Vaccine science by press release has to stop”
11 Nov, 2020 | 09:25h | UTCWhy the Pfizer and BioNTech vaccine is a cause for optimism — and skepticism – Vox
Related commentaries: Champagne and questions greet first data showing that a COVID-19 vaccine works – Science AND 90% efficacy for Pfizer’s COVID-19 mRNA vaccine is striking. But we need to wait for the full data – The Conversation
See also: Science by press release: When the story gets ahead of the science – CNN
[Preprint] A machine learning study of 534,023 Medicare beneficiaries with COVID-19: Implications for personalized risk prediction to identify candidates for early vaccine and therapeutics allocation.
12 Nov, 2020 | 09:15h | UTCCommentary: Largest-to-Date COVID Mortality Study Released – MedPage Today (free registration required)