Geriatrics
Pharmacoepidemiological Study: Association of Antidepressant Use With Drug-Related Extrapyramidal Symptoms
22 Jun, 2018 | 02:28h | UTCAssociation of Antidepressant Use With Drug-Related Extrapyramidal Symptoms: A Pharmacoepidemiological Study – Journal of Clinical Psychopharmacology (link to abstract – $ for full-text)
Commentaries: Incidence of Extrapyramidal Symptoms Higher With Certain Antidepressants – MPR (free) AND Antidepressants tied to Parkinson’s-like symptoms – Univadis (free registration required)
“Observational study: Incidence of EPSs with antidepressants. RRs: duloxetine, 5.68; mirtazapine, 3.78; citalopram, 3.47; escitalopram, 3.23; paroxetine, 3.07; sertraline, 2.57; venlafaxine, 2.37; bupropion, 2.31; and fluoxetine, 2.03 (all significant)” (via @psychopharmacol see Tweet)
Guide: Age-attuned Hospice Care
18 Jun, 2018 | 00:19h | UTCAge-attuned Hospice care: An opportunity to better end of life care for older people – StCristopher’s (free PDF) (via @hospicedoctor see tweet)
“Despite the evidence that more people will die of frailty and multiple long-term conditions than of cancer, our services for those moving towards the end of their life remain focussed on the needs of the latter group”
Cohort Study: Older Age Associated with Worse Outcomes in Major Depressive Disorder
15 Jun, 2018 | 01:09h | UTCAssociations between age and the course of major depressive disorder: a 2-year longitudinal cohort study – The Lancet Psychiatry (link to abstract – $ for full-text)
Commentaries: Older age tied to poorer course of major depressive disorder – MedicalXpress (free) AND Worse Depression Trajectory in Old Age – MedPage Today (free registration required)
Randomized Trial: Antipsychotic Treatment of Very Late-onset Schizophrenia-like Psychosis
15 Jun, 2018 | 00:55h | UTCCommentaries: Very late-onset schizophrenia-like psychosis: positive findings but questions remain unanswered – The Lancet Psychiatry (free) AND Low-Dose Antipsychotic Effective in Late-Onset Psychosis – Medscape (free registration required) AND Low-dose amisulpride effective for late-onset psychosis – Healio (free registration required)
Guideline: Type 2 Diabetes Mellitus in Older People
1 Jun, 2018 | 03:48h | UTCCommentary: New guidance on treating diabetes in elderly and frail adults – University of Exeter, via EurekAlert (free)
Cohort Study: Incidence and Cost of Medication Harm in Older Adults Following Hospital Discharge
24 May, 2018 | 23:35h | UTCCommentaries: Medication-related harm is common in older adults after hospital discharge – OnMedica (free) AND Medication-related harm found to be common among older adults, but preventable – News Medical (free)
ASCO Guideline for Geriatric Oncology
24 May, 2018 | 23:37h | UTC
Randomized Controlled Trial: Exercise Training Does Not Slow Dementia Progression
18 May, 2018 | 02:29h | UTCCommentaries: Exercise Doesn’t Slow Cognitive Decline in Patients with Dementia – NEJM Physician’s First Watch (free) AND Rigorous exercise does not halt dementia decline, study concludes – The Guardian (free) AND Expert reaction to effects of exercise on dementia in old people – Science Media Centre (free) AND Exercise ‘doesn’t slow’ progression of dementia – NHS Choices (free)
Research: Amyloid PET Scan for Predicting Alzheimer’s Disease in Mild Cognitive Impairment
16 May, 2018 | 01:19h | UTCCommentaries: Biomarkers, PET imaging may predict cognitive decline en route to Alzheimer’s – Health Imaging (free) AND Amyloid PET Scan Can Predict Progression to Alzheimer’s in Patients With Mild Cognitive Impairment – MedicalResearch.com (free)
Related Studies: Elevated Brain Amyloid and Subsequent Cognitive Decline Among Cognitively Normal Persons (link to abstract and free commentaries) AND Identifying incipient dementia individuals using machine learning and amyloid imaging (free full-text and commentaries) AND High performance plasma amyloid-β biomarkers for Alzheimer’s disease (link to abstract and free commentaries)
Study: Visual Screening Tool Improves Prediction of Developing Dementia
16 May, 2018 | 01:18h | UTCImproving Prediction of Dementia in Primary Care – Annals of Family Medicine (free)
Commentaries: Screening Tool Improves Dementia Prediction – Medscape (free registration required) AND Visual Test Could Help Predict Dementia Risk in Elders – NEJM Physician’s First Watch (free)
Guideline: Deprescribing Benzodiazepines
16 May, 2018 | 01:01h | UTCDeprescribing benzodiazepine receptor agonists – Canadian Family Physician (free) (via @Deprescribing)
Related: CaDeN Deprescribing Guidelines and Algorithms (free) AND 11 Drugs You Should Seriously Consider Deprescribing – Medscape Slideshow (free registration required) AND Current and future perspectives on the management of polypharmacy – BMC Family Practice (free)
Meta-analysis: Psychological Interventions for Chronic Pain in Older Adults
10 May, 2018 | 17:48h | UTCAssociation Between Psychological Interventions and Chronic Pain Outcomes in Older Adults: A Systematic Review and Meta-analysis – JAMA Internal Medicine (free for a limited period)
Author Interview: Association Between Psychological Interventions and Chronic Pain Outcomes in Older Adults (free)
Commentaries: Psychological interventions can help treat chronic pain in seniors – UPI (free) AND Not All In Your Head: Psychological Therapies Not a Panacea for Pain – MedicalResearch.com (free)
Cohort Study: Association of Mild Traumatic Brain Injury with Later Dementia
10 May, 2018 | 17:44h | UTCAssociation of Mild Traumatic Brain Injury With and Without Loss of Consciousness With Dementia in US Military Veterans – JAMA Neurology (free for a limited period)
Editorial: Risk of Dementia Outcomes Associated With Traumatic Brain Injury During Military Service (free)
Commentaries: Dementia Risk Doubles Following Concussion, UCSF Study Shows – University of California San Francisco (free) AND Vets with Head Injury More Likely To Develop Dementia – MedicalResearch.com (free)
See two recent cohort studies with similar results: Long-term risk of dementia among people with traumatic brain injury (link to abstract and free commentaries) AND Traumatic Brain Injury and the Risk of Dementia Diagnosis (free article and commentaries)
Perspective: Advanced Health Directives for Patients with Dementia
10 May, 2018 | 17:41h | UTCAlzheimer’s? Your Paperwork May Not Be in Order – The New York Times (10 articles per month are free)
Related: New Document for Patients: Advanced Health Directive for Dementia (free document and commentaries)
Meta-Analysis: Economics of Palliative Care for Hospitalized Adults With Serious Illness
3 May, 2018 | 20:32h | UTCEconomics of Palliative Care for Hospitalized Adults With Serious Illness: A Meta-analysis – JAMA Internal Medicine (free for a limited period)
Commentaries: Study: Palliative Care Reduces Hospital Stay, Cost of Sickest Patients – U.S. News (free) AND Prompt Palliative Care Saves Money, Especially in Sickest Patients – MedPage Today (free registration required)
Cohort Study: Dietary Intake and Age at Natural Menopause
3 May, 2018 | 20:00h | UTCCommentaries: Diet rich in fish and legumes may help to delay natural menopause – BMJ, via EurekAlert (free) AND Expert reaction to study looking at dietary intake and age at menopause – Science Media Centre (free) AND Oily fish and fresh beans may be linked to a later menopause – NHS Choices (free)
Observational Study: Development and Validation of a Hospital Frailty Risk Score for Older People in Acute Care Settings
3 May, 2018 | 19:45h | UTCCommentaries: What proportion of older adults in hospital are frail? – The Lancet (free) AND Research helps frail older people in hospitals – University of Leicester, via EurekAlert (free)
Case–Crossover Study: Association Between Home Care Visits and Same-Day Emergency Department Use
3 May, 2018 | 18:44h | UTCCommentaries: Seniors more likely to visit the ER after nurse’s home care visit – McMaster University (free) AND Seniors visit ER’s more frequently after nurse’s home care visit – UPI (free)
Polypharmacy Guidance, Realistic Prescribing
27 Apr, 2018 | 02:58h | UTCPolypharmacy Guidance, Realistic Prescribing 3 rd Edition, 2018 – Scottish Government Polypharmacy Model of Care Group (free PDF) (via @trishgreenhalgh)
Related Reviews: Current and future perspectives on the management of polypharmacy – BMC Family Medicine (free) AND Routine deprescribing of chronic medications to combat polypharmacy – Therapeutic Advances in Drug Safety (free) AND Polypharmacy—an Upward Trend with Unpredictable Effects – Deutsches Ärzteblatt international (free) AND Clinical Consequences of Polypharmacy in Elderly – Expert Opinion on Drug Safety (free)
Perspective: The Mediterranean Diet’s Fight Against Frailty
27 Apr, 2018 | 02:54h | UTCThe Mediterranean Diet’s Fight Against Frailty – JAMA (free for a limited period)
Review: Optimised Care of Elderly Patients with Acute Coronary Syndrome
27 Apr, 2018 | 02:39h | UTCOptimised care of elderly patients with acute coronary syndrome – European Heart Journal: Acute Cardiovascular Care (free) (via @krychtiukmd see Tweet)
USPSTF Draft Recommendation: Screening for Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults
27 Apr, 2018 | 01:31h | UTCUSPSTF Draft Recommendation Statement: Intimate Partner Violence, Elder Abuse, and Abuse of Vulnerable Adults: Screening (free)
Commentaries: USPSTF urges abuse screening for reproductive-aged women – MedicalXpress (free) AND USPSTF Recommends Screening for Partner Violence in Reproductive-Aged Women – Clinical Advisor (free)
“The USPSTF recommends that clinicians screen for intimate partner violence (IPV) in women of reproductive age and provide or refer women who screen positive to ongoing support services.”
Meta-Analysis: Case Managers Improve Outcomes for People with Dementia and Their Carers
27 Apr, 2018 | 01:23h | UTCCase managers improve outcomes for people with dementia and their carers – NIHR Signal (free)
Original Article: The effectiveness of community-based coordinating interventions in dementia care: a meta-analysis and subgroup analysis of intervention components – BMC Health Services Research (free)
“The review suggests that nurses may be particularly well placed to act as case managers for people with dementia, perhaps because they have the skills to perform the broad range of tasks associated with the role.” (via @NIHR_DC see Tweet)
Retrospective Cohort: Recent Opioid Use and Fall-related Injury Among Older Patients With Trauma
25 Apr, 2018 | 13:48h | UTCCommentary: Opioid use linked to increased risk of falls, death in older adults – CMAJ, via EurekAlert (free)
Viewpoint: Tube Feeding and Deteriorating Patients
25 Apr, 2018 | 12:54h | UTCDavid Oliver: Tube feeding and deteriorating patients—guidelines can take us only so far – The BMJ (free)
Related Guidelines: American Geriatrics Society Feeding Tubes in Advanced Dementia Position Statement (free) AND ESPEN guideline on ethical aspects of artificial nutrition and hydration (free)
Related Reviews: Artificial nutrition and hydration in advanced dementia – Canadian Family Physician (free) AND End-of-life issues in advanced dementia: Part 1: goals of care, decision-making process, and family education – Canadian Family Physician (free) AND End-of-life issues in advanced dementia: Part 2: management of poor nutritional intake, dehydration, and pneumonia – Canadian Family Physician (free) AND Advanced Dementia – New England Journal of Medicine (free)