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Geriatrics

Long Covid: Largest post-acute COVID-19 study to date examined the health outcomes in more than 73,000 people who’d had COVID-19 and were not hospitalized

23 Apr, 2021 | 08:48h | UTC

High-dimensional characterization of post-acute sequalae of COVID-19 – Nature

Commentary: Among COVID-19 survivors, an increased risk of death, serious illness – Washington University School of Medicine

 

Commentary on Twitter (thread – click for more)

 

Podcast: Dementia Made Simple

20 Apr, 2021 | 05:21h | UTC

#268 Dementia Made Simple with Dr. Josh Uy – The Curbsiders

 

Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months

16 Apr, 2021 | 06:35h | UTC

Evolving changes in mortality of 13,301 critically ill adult patients with COVID-19 over 8 months – Intensive Care Medicine

 

Commentary on Twitter

 

USPSTF Statement: Insufficient evidence to recommend Vitamin D deficiency screening

14 Apr, 2021 | 01:47h | UTC

Vitamin D Deficiency in Adults: Screening – U.S. Preventive Services Task Force

Evidence Report: Screening for Vitamin D Deficiency in Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force

Editorial: The USPSTF 2021 Recommendations on Screening for Asymptomatic Vitamin D Deficiency in Adults: The Challenge for Clinicians Continues – JAMA AND Why USPSTF Still Finds Insufficient Evidence to Support Screening for Vitamin D Deficiency – JAMA Network Open

JAMA Patient Page: Screening for Vitamin D Deficiency in Adults

 

Guidance: Using Ventilation and filtration to reduce aerosol transmission of COVID-19 in long-term care homes

15 Apr, 2021 | 06:54h | UTC

Using Ventilation and filtration to reduce aerosol transmission of COVID-19 in long-term care homes – Public Health Agency of Canada

 

Commentary on Twitter

 

Cohort study: Higher cumulative exposure to Thiazide diuretics linked to an increased risk of skin cancer in people older than 65 years

13 Apr, 2021 | 05:08h | UTC

Association between antihypertensive medications and risk of skin cancer in people older than 65 years: a population-based study – Canadian Medical Association Journal

Commentaries: Thiazides May Up Risk for Skin Cancer in Older Adults – HealthDay AND Some blood pressure medication linked to higher risk of skin cancer, study finds – CTV News

Related study: Case-Control Study: Possible Association of Hydrochlorothiazide Use and Risk of Melanoma

 

Study: Protocoled time-limited trials among critically ill patients with advanced medical illnesses were associated with reduction of nonbeneficial ICU treatments

13 Apr, 2021 | 05:16h | UTC

Evaluation of Time-Limited Trials Among Critically Ill Patients With Advanced Medical Illnesses and Reduction of Nonbeneficial ICU Treatments – JAMA Internal Medicine (free for a limited period)

Commentary: Time-Limited Trials and Potentially Nonbeneficial Treatment in the ICU—Willing to Wait for It – JAMA Internal Medicine AND Time-limited trials may decrease the length of stay of critically ill patients in the intensive care unit – 2 Minute Medicine

Author interview: Time-Limited Trials Among Patients With Advanced Illness to Reduce Nonbeneficial ICU Treatments

Related review: Time-limited trial of intensive care treatment: an overview of current literature – Intensive Care Medicine

 

Long-term mortality of elderly patients after intensive care unit admission for COVID-19

14 Apr, 2021 | 02:09h | UTC

Long-term mortality of elderly patients after intensive care unit admission for COVID-19 – Intensive Care Medicine

 

Commentary on Twitter

 

Cohort Study: Effects of fluoroquinolones on outcomes of patients with aortic dissection or aneurysm

13 Apr, 2021 | 05:05h | UTC

Effects of Fluoroquinolones on Outcomes of Patients With Aortic Dissection or Aneurysm – Journal of the American College of Cardiology

Commentary: Fluoroquinolones Associated With Increased Risk of Aortic Dissection, Aneurysm – American College of Cardiology

Related: Another study suggests fluoroquinolone use may increase the risk of development of aortic aneurysms (study and commentaries) AND Link between fluoroquinolones, aorta problems may not be as strong as thought AND Study: Oral Fluoroquinolones and Risk of Mitral and Aortic Regurgitation AND FDA Warns About Increased Risk of Aortic Dissection and Ruptures of Aortic Aneurism with Fluoroquinolones AND Meta-analysis: Fluoroquinolones and the Risk of Aortopathy AND Study: Oral Fluoroquinolone and the Risk of Aortic Dissection AND Research: Fluoroquinolone use and risk of aortic aneurysm and dissection

 

Clinical Review: Screening and management of atrial fibrillation in primary care

13 Apr, 2021 | 05:09h | UTC

Screening and management of atrial fibrillation in primary care – The BMJ

 

AHA/ASA Scientific Statement: Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery

12 Apr, 2021 | 00:50h | UTC

Perioperative Neurological Evaluation and Management to Lower the Risk of Acute Stroke in Patients Undergoing Noncardiac, Nonneurological Surgery: A Scientific Statement From the American Heart Association/American Stroke Association – Circulation

 

Commentary on Twitter

 

RCT: Among patients with peripheral artery disease, low-intensity exercise was significantly less effective than high-intensity exercise for improving 6-minute walk distance

7 Apr, 2021 | 01:31h | UTC

Effect of Low-Intensity vs High-Intensity Home-Based Walking Exercise on Walk Distance in Patients With Peripheral Artery Disease: The LITE Randomized Clinical Trial – JAMA (free for a limited period)

Commentary: No pain, no gain in exercise for peripheral artery disease – ‘You’ve got to walk with pain to reap benefits’ – Northwestern University

 

Commentary on Twitter

 

Cohort study: Risk of suicide attempt in patients with recent diagnosis of mild cognitive impairment or dementia

7 Apr, 2021 | 01:08h | UTC

Risk of Suicide Attempt in Patients With Recent Diagnosis of Mild Cognitive Impairment or Dementia – JAMA Psychiatry (link to abstract – $ for full-text)

Commentaries: Recent Diagnosis of Cognitive Impairment, Dementia May Increase Suicide Risk – Psychiatric News Alert AND Suicide Attempts Spike Soon After Dementia Diagnosis – HealthDay

 

M-A: Non-drug therapies as good as or better than drugs for treating depression in people with dementia

2 Apr, 2021 | 09:05h | UTC

Comparative efficacy of interventions for reducing symptoms of depression in people with dementia: systematic review and network meta-analysis – The BMJ

Commentaries: Non-drug therapies as good as or better than drugs for treating depression in people with dementia – The BMJ AND Social prescribing may help reduce symptoms of depression in people with dementia – The BMJ Opinion AND Nondrug Interventions Can Help Alleviate Depression in Dementia Patients – HealthDay

 

ERC and ESICM Guidelines: Post-resuscitation Care

26 Mar, 2021 | 08:41h | UTC

European Resuscitation Council and European Society of Intensive Care Medicine guidelines 2021: post-resuscitation care – Intensive Care Medicine

 

Commentary on Twitter

 

USPSTF Statement: Current evidence is insufficient to recommend screening for hearing loss in older adults

24 Mar, 2021 | 08:12h | UTC

Screening for Hearing Loss in Older Adults – U.S. Preventive Services Task Force

Editorial: Screening for Hearing Loss in Older Adults: Insufficient Evidence Does Not Mean Insufficient Benefit – JAMA AND United States Preventive Services Task Force Recommendation for Hearing-Loss Screening Among Older Adults: An Opportunity in Insufficient Evidence – AMA Otolaryngology-Head & Neck Surgery AND USPSTF Recommendations for Hearing Loss Screening in Asymptomatic Older Adults—A Case of Missing Evidence and Missing Treatment Options – JAMA Network Open

Evidence Report: Screening for Hearing Loss in Older Adults: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Author interview: USPSTF Recommendation: Screening for Hearing Loss in Older Adults – JAMA

JAMA Patient Page: Screening for Hearing Loss in Older Adults

 

WHO Report: Kicking off a global conversation about ageism

19 Mar, 2021 | 08:12h | UTC

Global report on ageism – World Health Organization

News release: Kicking off a global conversation about ageism: launch of the first UN Global report on ageism – World Health Organization

 

M-A: Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments

19 Mar, 2021 | 07:52h | UTC

Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta‐analysis – Cochrane Library

 

Population Study: Past Covid-19 confers 80.5% protection against reinfection, which decreases to 47.1% in those aged 65 years and older

18 Mar, 2021 | 09:06h | UTC

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study – The Lancet

Commentaries: Risk of SARS-CoV-2 reinfection after natural infection – The Lancet AND COVID-19 Reinfection: More Common Than We Think? – MedPage Today (free registration required)

 

Commentary on Twitter

 

RCT: No benefit from marine Omega-3 fatty acid and Vitamin D supplementation on incident atrial fibrillation

17 Mar, 2021 | 02:38h | UTC

Effect of Marine Omega-3 Fatty Acid and Vitamin D Supplementation on Incident Atrial Fibrillation: A Randomized Clinical Trial – JAMA (free for a limited period)

Editorial: Omega-3 Fatty Acids and Atrial Fibrillation – JAMA (free for a limited period)

 

Systematic review | Hospital at home: home‐based end‐of‐life care

17 Mar, 2021 | 02:31h | UTC

Hospital at home: home‐based end‐of‐life care – Cochrane Library

Summary: Home-based end-of-life care – Cochrane Library

 

Meta-analysis of randomized trials bring into question the belief that betablockers cause depression

16 Mar, 2021 | 01:47h | UTC

Do β-Blockers Cause Depression? Systematic Review and Meta-Analysis of Psychiatric Adverse Events During β-Blocker Therapy – Hypertension (link to abstract – $ for full-text)

News release: Beta-blockers not likely to cause depression yet may contribute to sleep disturbances – American Heart Association

Commentary: Beta blockers not associated with risk of depression – Charité – Universitätsmedizin Berlin

 

Central nervous system–active polypharmacy common among older adults with dementia in the US

16 Mar, 2021 | 01:45h | UTC

Prevalence of Central Nervous System–Active Polypharmacy Among Older Adults With Dementia in the US – JAMA (free for a limited period)

Commentaries: CNS-Active Polypharmacy Examined in Seniors With Dementia – HealthDay AND A Trio That Could Spell Trouble: Many with Dementia Take Risky Combinations of Medicines – Michigan Medicine – University of Michigan AND Older Adults With Dementia at Risk From Taking Multiple Psychotropics, Study Suggests – Psychiatric News Alert

 

Commentary on Twitter

 

Phase 2 RCT: Donanemab in early Alzheimer’s Disease

14 Mar, 2021 | 20:21h | UTC

Donanemab in Early Alzheimer’s Disease – New England Journal of Medicine (link to abstract – $ for full-text)

Commentaries: Experimental Alzheimer’s drug could slow cognitive decline in patients, early results suggest – CNN AND Alzheimer’s study shows mixed results for Lilly’s donanemab on secondary outcomes – First World Pharma

 

Commentary on Twitter

 

M-A: Little benefit from antidepressants for low back pain

11 Mar, 2021 | 08:02h | UTC

Efficacy, acceptability, and safety of antidepressants for low back pain: a systematic review and meta-analysis – Systematic Reviews

Commentary: Antidepressants provide no important benefits for managing low back pain – News Medical

Related meta-analysis: Little benefit from antidepressants for the treatment of back pain and osteoarthritis (study and commentaries)

 

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