Geriatrics
Cohort Study: Association of subjective memory complaints with white matter hyperintensities and cognitive decline among older adults.
20 Apr, 2022 | 09:17h | UTCCommentary: Memory complaints associated with structural brain abnormalities and increased dementia risk – HealthImaging
Commentary on Twitter
In this cohort study, subjective memory complaints (SMCs) were associated with larger white matter hyperintensity volumes and faster cognitive decline, suggesting that SMCs are an important sign of cognitive impairment. https://t.co/mpCXDbylnf
— JAMA Network Open (@JAMANetworkOpen) April 15, 2022
Opinion | Low-grade prostate cancer (Gleason score 6): time to stop calling it cancer.
19 Apr, 2022 | 02:29h | UTCLow-Grade Prostate Cancer: Time to Stop Calling It Cancer – Journal of Clinical Oncology
Commentary: Doctors suggest new names for low-grade prostate cancer – Associated Press
Palliative care for older people with dementia—we need a paradigm shift in our approach – “Advance care planning (ACP) is a central tenet of good dementia palliative care”.
19 Apr, 2022 | 01:30h | UTC
Cluster RCT: BABEL (Better tArgeting, Better outcomes for frail ELderly patients) advance care planning: a comprehensive approach to advance care planning in nursing homes.
19 Apr, 2022 | 01:26h | UTC
Commentary: Loneliness and health.
18 Apr, 2022 | 10:16h | UTCLoneliness and health – Nature Reviews Disease Primers (if the link is paywalled, try this one)
Related:
The prevalence of loneliness across 113 countries: systematic review and meta-analysis – The BMJ
Social Isolation and Loneliness – World Health Organization
Psychological Distress and Loneliness Reported by US Adults in 2018 and April 2020 – JAMA
Commentary on Twitter
In this Comment, Louise Hawkley discusses associations of #Loneliness with increased mortality and disease risk, and that a multi-level approach including individuals, community organizations and society is needed to reduce loneliness.@NORCNewshttps://t.co/CzP5fR6G0n pic.twitter.com/X3use2Aybe
— Nature Reviews Disease Primers (@DiseasePrimers) April 14, 2022
An observational study in patients with chronic kidney disease suggests the optimum range of water intake is around 1–2 L/day.
18 Apr, 2022 | 10:12h | UTC
RCT: Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people.
18 Apr, 2022 | 10:01h | UTCEditorial: Pointing a FINGER at the contribution of lifestyle to cardiovascular events and dementia
Commentary on Twitter
Effect of a multi-domain lifestyle intervention on cardiovascular risk in older people: the FINGER trial https://t.co/fkUJQQ9MyZ @escardio #EHJ #ESCYoung #cardiotwitter @ehj_ed @rladeiraslopes pic.twitter.com/sU0LVF8agJ
— European Society of Cardiology Journals (@ESC_Journals) February 1, 2022
Population based cohort study: Healthy lifestyle and life expectancy with and without Alzheimer’s dementia.
14 Apr, 2022 | 08:27h | UTCEditorial: Healthy lifestyles and more life years without dementia – The BMJ
Commentary on Twitter
A new US study suggests that a healthy lifestyle is associated with a longer life expectancy among both men and women, and they lived a larger proportion of their remaining years without Alzheimer’s diseasehttps://t.co/eXsQRd6mon
— The BMJ (@bmj_latest) April 14, 2022
RCT: A home-based, walking exercise behavior change intervention increased walking distance in adults with peripheral artery disease.
13 Apr, 2022 | 11:02h | UTCEffect of a Home-Based, Walking Exercise Behavior Change Intervention vs Usual Care on Walking in Adults With Peripheral Artery Disease: The MOSAIC Randomized Clinical Trial – JAMA (free for a limited period)
Commentary on Twitter
In this study, among adults with peripheral artery disease, a home-based, #walking #exercise behavior change intervention, compared with usual care, increased 6-minute walking distance at 3 months. https://t.co/5ea3YOWlN0 @LindsayBearne pic.twitter.com/s06ONnki9y
— JAMA (@JAMA_current) April 12, 2022
Review | Less is more: deprescribing medications in older adults with kidney disease.
13 Apr, 2022 | 10:44h | UTCLess is More: Deprescribing Medications in Older Adults with Kidney Disease: A Review – Kidney360
Related:
AGA clinical practice update on de-prescribing of proton pump inhibitors.
Development of a metric to detect and decrease low-value prescribing in older adults.
Deprescribing in palliative patients with cancer: a concise review of tools and guidelines.
A narrative review of evidence to guide deprescribing among older adults.
Polypharmacy Management in Older Patients – Mayo Clinic Proceedings
Eliminating Medication Overload: A National Action Plan
Position Statement: Reducing Inappropriate Medication Use & Polypharmacy (several articles and commentaries on the subject)
New insights into the genetic etiology of Alzheimer’s disease and related dementias.
13 Apr, 2022 | 10:26h | UTCNews Release:
Commentaries:
42 previously unknown genes discovered for Alzheimer’s disease – CNN
Alzheimer’s disease research takes ‘major leap forward’ – BBC
Commentary on Twitter
A meta-analysis in @NatureGenet of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia. https://t.co/EAtdlRozld pic.twitter.com/5rtWWt4HyS
— Nature Portfolio (@NaturePortfolio) April 11, 2022
UK clinical guideline for the prevention and treatment of osteoporosis.
11 Apr, 2022 | 01:33h | UTCUK clinical guideline for the prevention and treatment of osteoporosis – Archives of Osteoporosis
Effects of aspirin on dementia and cognitive function in diabetic patients: the ASCEND trial.
11 Apr, 2022 | 00:50h | UTCOriginal Study: Randomized Trial: Effects of Aspirin for Primary Prevention in Persons with Diabetes
Commentary on Twitter (images under a https://creativecommons.org/licenses/by/4.0/ license)
Does aspirin have an effect on dementia and cognitive function? Discover it in the EHJ!https://t.co/u5X1fxrULk#aspirin #dementia #CVD #ASCEND #trial #diabetes #cardiotwitter @escardio @ESC_Journals pic.twitter.com/TyrnUnf0MN
— EHJ Editor-in-Chief (@ehj_ed) April 8, 2022
Cohort Study: Use of Phosphodiesterase 5 Inhibitors linked to increased risk of ocular adverse events.
8 Apr, 2022 | 11:04h | UTCRisk of Ocular Adverse Events Associated With Use of Phosphodiesterase 5 Inhibitors in Men in the US – JAMA Ophthalmology (free for a limited period)
News Release: U.S. insurance claims show strong link between ED medications and vision problems – University of British Columbia
Commentaries:
Phase 4 Studies on Phosphodiesterase 5 Inhibitors – JAMA Ophthalmology (free for a limited period)
Could Viagra, Cialis Raise Men’s Odds for Eye Trouble? – HealthDay
RCT: Clinical effectiveness of one ultrasound guided intra-articular corticosteroid and local anesthetic injection for hip osteoarthritis.
7 Apr, 2022 | 08:37h | UTCNews Release: Steroid injections may provide longer lasting benefits for hip pain than current best care – BMJ
Commentary on Twitter
Adding an ultrasound guided corticosteroid and local anaesthetic injection to advice and education offers rapid and sustained improvements in pain and function, finds new research https://t.co/fQHzvKv2wL
— The BMJ (@bmj_latest) April 7, 2022
RCT: Effect of intramuscular vs. intra-articular glucocorticoid injection on pain among adults with knee osteoarthritis.
7 Apr, 2022 | 08:35h | UTC
Commentary on Twitter
This RCT found IM steroid injections were inferior to intrarticular injections for reducing pain in patients with knee osteoarthritis at 4 weeks but were noninferior at 8 and 24 weeks after injection. https://t.co/opq1C2BP8c pic.twitter.com/ucx4lvRDJQ
— JAMA Network Open (@JAMANetworkOpen) April 5, 2022
Retinal photograph-based deep learning predicts biological age, and stratifies morbidity and mortality risk.
7 Apr, 2022 | 08:18h | UTC
Systematic Review: Algorithm‐based pain management for people with dementia in nursing homes.
7 Apr, 2022 | 07:52h | UTCAlgorithm‐based pain management for people with dementia in nursing homes – Cochrane Library
Review: Atrial fibrillation in older adults with cancer.
6 Apr, 2022 | 09:53h | UTCAtrial fibrillation in older adults with cancer – Journal of Geriatric Cardiology
Practice review: Evidence-based and effective management of anemia in palliative care patients.
1 Apr, 2022 | 08:21h | UTC
Practice review: Evidence-based management approaches for patients with severe chronic obstructive pulmonary disease (COPD).
1 Apr, 2022 | 08:29h | UTC
Practice review: Evidence-based and effective management of fatigue in patients with advanced cancer.
1 Apr, 2022 | 08:26h | UTC
Study Commentary: Older women with breast cancer chose less aggressive treatment when they used a decision aid.
1 Apr, 2022 | 08:16h | UTC
Commentary on Twitter
Open access in May's BJS: Bridging the age gap in breast cancer: two decision support interventions for older women with operable breast cancer https://t.co/s70uEVyAxU @AmyLightnerMD @bplwijn @des_winter @ksoreide @MalinASund @evanscolorectal @nfmkok @robhinchliffe1 @young_bjs pic.twitter.com/IUuiUldUTS
— BJS (@BJSurgery) June 11, 2021
RCT: Single-incision mini-slings for stress urinary incontinence in women.
31 Mar, 2022 | 08:35h | UTCSingle-Incision Mini-Slings for Stress Urinary Incontinence in Women – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Single-incision mini-slings effective for stress urinary incontinence in women – Healio (free registration required)
Commentary on Twitter
For stress urinary incontinence in women, mini-slings were noninferior to midurethral slings with respect to patient-reported success at 15 months. https://t.co/Ag5p2u2WZW pic.twitter.com/PcajqXTiLW
— NEJM (@NEJM) March 30, 2022
M-A: Psychological interventions for chronic, non-specific low back pain.
31 Mar, 2022 | 08:20h | UTCNews Release: Study sheds light on psychological therapies for chronic low back pain – British Medical Journal