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Geriatrics

Rapidly progressive dementias — etiologies, diagnosis and management.

10 May, 2022 | 10:59h | UTC

Rapidly progressive dementias — aetiologies, diagnosis and management – Nature Reviews Neurology (if the link is paywalled, try this one in PMC)

 


Review: Assessment and management of cognitive function in patients with prostate cancer treated with second-generation androgen receptor pathway inhibitors.

10 May, 2022 | 10:32h | UTC

Assessment and Management of Cognitive Function in Patients with Prostate Cancer Treated with Second-Generation Androgen Receptor Pathway Inhibitors – CNS Drugs

 


Systematic Review: Comprehensive Geriatric Assessment for community‐dwelling, high‐risk, frail, older people.

9 May, 2022 | 01:43h | UTC

Comprehensive Geriatric Assessment for community‐dwelling, high‐risk, frail, older people – Cochrane Library

Summary: Comprehensive Geriatric Assessment for older people in the community at risk of poor health outcomes – Cochrane Library

 


Review: Diagnosis and management of lumbar spinal stenosis.

4 May, 2022 | 10:45h | UTC

Diagnosis and Management of Lumbar Spinal Stenosis: A Review – JAMA (free for a limited period)

Audio Clinical Review: Lumbar Spinal Stenosis: A Review – JAMA

 


Review: Opioids and falls risk in older adults.

4 May, 2022 | 10:27h | UTC

Opioids and Falls Risk in Older Adults: A Narrative Review – Drugs & Aging

 


Cohort Study: Characterizing older adults’ risk of harm from blood-pressure lowering medications.

4 May, 2022 | 10:26h | UTC

Characterising older adults’ risk of harm from blood-pressure lowering medications: a sub-analysis from the PRIME study – Age and Ageing

 


Cohort study: frailty is significantly associated with medication-related harm.

4 May, 2022 | 08:17h | UTC

A multi-centre cohort study on healthcare use due to medication-related harm: the role of frailty and polypharmacy – Age and Ageing

 


Perspective: Less pharmacotherapy is more in delirium.

3 May, 2022 | 10:56h | UTC

Less pharmacotherapy is more in delirium – Intensive Care Medicine (if the link is paywalled, try this one)

Related:

Pharmacological interventions for the treatment of delirium in critically ill adults – Cochrane Library

Non‐pharmacological interventions for preventing delirium in hospitalised non‐ICU patients – Cochrane Library

Delirium in critical illness: clinical manifestations, outcomes, and management – Intensive Care Medicine

Distribution of delirium motor subtypes in the intensive care unit: a systematic scoping review – Critical Care

Pharmacological and non-pharmacological interventions to prevent delirium in critically ill patients: a systematic review and network meta-analysis – Intensive Care Medicine

Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine

 

Commentary on Twitter

 


M-A: Comparative safety and efficacy of cognitive enhancers for Alzheimer’s dementia.

1 May, 2022 | 23:10h | UTC

Comparative safety and efficacy of cognitive enhancers for Alzheimer’s dementia: a systematic review with individual patient data network meta-analysis – BMJ Open

 


Study Commentary | People of all ages benefit from drugs to lower blood pressure.

29 Apr, 2022 | 08:18h | UTC

People of all ages benefit from drugs to lower blood pressure – National Institute for Health and Care Research

Original Study: Age-stratified and blood-pressure-stratified effects of blood-pressure-lowering pharmacotherapy for the prevention of cardiovascular disease and death: an individual participant-level data meta-analysis – The Lancet

 


Systematic Review: Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia.

29 Apr, 2022 | 11:09h | UTC

Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia – Cochrane Library

Summary: How accurate are remote, virtual assessments at diagnosing dementia? – Cochrane Library

 


Study Commentary | Palliative and end of life care should not wait for a prediction of death.

28 Apr, 2022 | 10:44h | UTC

Palliative and end of life care should not wait for a prediction of death – National Institute for Health and Care Research

Original Study: Timely community palliative and end-of-life care: a realist synthesis – BMJ Supportive & Palliative Care

 


Systematic Review: Psychological treatments for depression and anxiety in dementia and mild cognitive impairment.

28 Apr, 2022 | 10:33h | UTC

Psychological treatments for depression and anxiety in dementia and mild cognitive impairment – Cochrane Library

Summary: Psychological treatments for depression and anxiety in dementia and mild cognitive impairment – Cochrane Library

 


Podcast: Lower urinary tract symptoms, benign prostatic hyperplasia, and urinary incontinence.

28 Apr, 2022 | 08:00h | UTC

LUTS, BPH, and Urinary Incontinence Triple Distilled – The Curbsiders

 


USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.

27 Apr, 2022 | 08:16h | UTC

Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement – JAMA

Author Interview: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease – JAMA

Modeling Study: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force – JAMA

Evidence Report: Aspirin Use to Prevent Cardiovascular Disease and Colorectal CancerUpdated Evidence Report and Systematic Review for the US Preventive Services Task Force – JAMA

Patient Page: Use of Aspirin to Prevent Cardiovascular Disease – JAMA

Editorials:

Should Patients Take Aspirin for Primary Cardiovascular Prevention? Updated Recommendations From the US Preventive Services Task Force

Whom to Treat for Primary Prevention of Atherosclerotic Cardiovascular Disease: The Aspirin Dilemma – JAMA Internal Medicine

Aspirin for Primary Prevention—Time to Rethink Our Approach – JAMA Network Open

USPSTF Report on Aspirin for Primary Prevention – JAMA Cardiology

Commentaries:

USPSTF Report on Aspirin for Primary Prevention – American College of Cardiology

USPSTF Finalizes Tougher Stance on Aspirin in Primary Prevention – TCTMD

Daily aspirin offers little to no benefit for most adults trying to prevent heart disease, new report says – STAT

U.S. Task Force Rejects Daily Aspirin for Heart Health in People Over 60 – HealthDay

 


Longitudinal associations of mental disorders with dementia: 30-year analysis of 1.7 million New Zealand citizens.

27 Apr, 2022 | 07:51h | UTC

Longitudinal Associations of Mental Disorders With Dementia: 30-Year Analysis of 1.7 Million New Zealand Citizens – JAMA Psychiatry

News Release: Mental disorders may increase risk for subsequent dementia – University of Michigan

Commentary: Mental Disorders Tied to Subsequent Dementia Onset – HealthDay

 

Commentary on Twitter

 


New horizons in evidence-based care for older people: individual participant data meta-analysis.

27 Apr, 2022 | 07:50h | UTC

New horizons in evidence-based care for older people: individual participant data meta-analysis – Age and Ageing

 


Persistent COVID-19 symptoms in a community study of 606,434 people in England.

26 Apr, 2022 | 08:48h | UTC

Persistent COVID-19 symptoms in a community study of 606,434 people in England – Nature Communications

 

Commentary on Twitter

 


Cohort Study: Association of cumulative blood pressure with cognitive decline, dementia, and mortality.

25 Apr, 2022 | 00:35h | UTC

Association of Cumulative Blood Pressure With Cognitive Decline, Dementia, and Mortality – Journal of the American College of Cardiology

Commentary: Association of Blood Pressure With Cognitive Decline, Dementia, and Mortality – American College of Cardiology

 


Anticholinergic medications and dementia: should we be worried?

25 Apr, 2022 | 00:14h | UTC

Commonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane

Original Review:

Anticholinergic burden (prognostic factor) for prediction of dementia or cognitive decline in older adults with no known cognitive syndrome – Cochrane Library

Editorial: Anticholinergic drugs and dementia: time for transparency in the face of uncertainty – Cochrane Library

Related:

Quantifying Anticholinergic Burden and Sedative Load in Older Adults with Polypharmacy: A Systematic Review of Risk Scales and Models – Drugs & Aging

Anticholinergic Drug Exposure and the Risk of Dementia: A Nested Case-Control Study – JAMA Internal Medicine

How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative

Anticholinergic drugs and risk of dementia: case-control study – The BMJ

 

Commentary on Twitter

 


Cohort Study: Progression to diabetes among older adults with Hemoglobin A1c–defined prediabetes was around 5% after a medium follow up of 2.3 years.

25 Apr, 2022 | 00:01h | UTC

Progression to Diabetes Among Older Adults With Hemoglobin A1c–Defined Prediabetes in the US – JAMA Network Open

Commentaries:

How Often Does Prediabetes in Seniors Escalate to Full-Blown Disease? – MedPage Today (link to abstract – $ for full-text)

New Research Explores Diabetes Progression Rate in Older Adults with Prediabetes – HCP Livre

Related Study: Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine and Commentary: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health

 

Commentary on Twitter

 


USPSTF Draft Statement: Postmenopausal women should not use hormone therapy to prevent chronic health problems.

20 Apr, 2022 | 10:15h | UTC

Draft Recommendation Statement: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons – U.S. Preventive Services Task Force

News Release: Task Force Issues Draft Recommendation Statement on Hormone Therapy for Preventing Chronic Conditions in Postmenopausal People – U.S. Preventive Services Task Force

Commentary: USPSTF Advises Against Hormone Therapy to Prevent Chronic Conditions – HealthDay

 


An observational study suggests coprescription of Phosphodiesterase Type 5 Inhibitors (i.e., sildenafil) and oral Nitrates is not associated with increased risk of adverse cardiovascular outcomes in male patients with ischemic heart disease.

20 Apr, 2022 | 10:11h | UTC

Adverse Events Associated With Coprescription of Phosphodiesterase Type 5 Inhibitors and Oral Organic Nitrates in Male Patients With Ischemic Heart Disease: A Case-Crossover Study – Annals of Internal Medicine

Commentaries:

PDE5 inhibitors didn’t increase cardiovascular events in men on nitrates for heart disease – ACP Internist

PDE5 Inhibitors Prescribed for Men on Oral Nitrates for IHD – HealthDay

 


Retinal age gap as a predictive biomarker of future risk of Parkinson’s disease.

21 Apr, 2022 | 09:54h | UTC

Retinal age gap as a predictive biomarker of future risk of Parkinson’s disease – Age and Ageing

Related: Retinal age gap as a predictive biomarker for mortality risk – British Journal of Ophthalmology (link to abstract – $ for full-text)

 


German guidelines for the diagnosis and treatment of varicose veins.

20 Apr, 2022 | 09:49h | UTC

S2k guidelines: diagnosis and treatment of varicose veins – Leitlinien und Empfehlungen

 


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