Geriatrics
Rapidly progressive dementias — etiologies, diagnosis and management.
10 May, 2022 | 10:59h | UTCRapidly progressive dementias — aetiologies, diagnosis and management – Nature Reviews Neurology (if the link is paywalled, try this one in PMC)
Review: Assessment and management of cognitive function in patients with prostate cancer treated with second-generation androgen receptor pathway inhibitors.
10 May, 2022 | 10:32h | UTC
Systematic Review: Comprehensive Geriatric Assessment for community‐dwelling, high‐risk, frail, older people.
9 May, 2022 | 01:43h | UTC
Review: Diagnosis and management of lumbar spinal stenosis.
4 May, 2022 | 10:45h | UTCDiagnosis and Management of Lumbar Spinal Stenosis: A Review – JAMA (free for a limited period)
Audio Clinical Review: Lumbar Spinal Stenosis: A Review – JAMA
Review: Opioids and falls risk in older adults.
4 May, 2022 | 10:27h | UTCOpioids and Falls Risk in Older Adults: A Narrative Review – Drugs & Aging
Cohort Study: Characterizing older adults’ risk of harm from blood-pressure lowering medications.
4 May, 2022 | 10:26h | UTC
Cohort study: frailty is significantly associated with medication-related harm.
4 May, 2022 | 08:17h | UTC
Perspective: Less pharmacotherapy is more in delirium.
3 May, 2022 | 10:56h | UTCLess pharmacotherapy is more in delirium – Intensive Care Medicine (if the link is paywalled, try this one)
Related:
Effectiveness of Bundle Interventions on ICU Delirium: A Meta-Analysis – Critical Care Medicine
Commentary on Twitter
⬇️ 💉Less medications (& ⬆️ awareness of behavioural interventions) is more in #delirium, common, challenging/costly (but often preventable) in #ICU. Despite lacking evidence, medications widely used.
Prevent/minimize addressing suspected contributors!
📎 https://t.co/fYWAsIcuiZ pic.twitter.com/DyC3agSP7w— Intensive Care Medicine (@yourICM) April 30, 2022
M-A: Comparative safety and efficacy of cognitive enhancers for Alzheimer’s dementia.
1 May, 2022 | 23:10h | UTC
Study Commentary | People of all ages benefit from drugs to lower blood pressure.
29 Apr, 2022 | 08:18h | UTC
Systematic Review: Diagnostic test accuracy of remote, multidomain cognitive assessment (telephone and video call) for dementia.
29 Apr, 2022 | 11:09h | UTCSummary: How accurate are remote, virtual assessments at diagnosing dementia? – Cochrane Library
Study Commentary | Palliative and end of life care should not wait for a prediction of death.
28 Apr, 2022 | 10:44h | UTCOriginal Study: Timely community palliative and end-of-life care: a realist synthesis – BMJ Supportive & Palliative Care
Systematic Review: Psychological treatments for depression and anxiety in dementia and mild cognitive impairment.
28 Apr, 2022 | 10:33h | UTC
Podcast: Lower urinary tract symptoms, benign prostatic hyperplasia, and urinary incontinence.
28 Apr, 2022 | 08:00h | UTCLUTS, BPH, and Urinary Incontinence Triple Distilled – The Curbsiders
USPSTF Recommendation Statement: Aspirin Use to Prevent Cardiovascular Disease.
27 Apr, 2022 | 08:16h | UTCAuthor Interview: USPSTF Recommendation: Aspirin Use for Cardiovascular Disease – JAMA
Modeling Study: Aspirin Use to Prevent Cardiovascular Disease and Colorectal Cancer: Updated Modeling Study for the US Preventive Services Task Force – JAMA
Patient Page: Use of Aspirin to Prevent Cardiovascular Disease – JAMA
Editorials:
Aspirin for Primary Prevention—Time to Rethink Our Approach – JAMA Network Open
USPSTF Report on Aspirin for Primary Prevention – JAMA Cardiology
Commentaries:
USPSTF Report on Aspirin for Primary Prevention – American College of Cardiology
USPSTF Finalizes Tougher Stance on Aspirin in Primary Prevention – TCTMD
U.S. Task Force Rejects Daily Aspirin for Heart Health in People Over 60 – HealthDay
Longitudinal associations of mental disorders with dementia: 30-year analysis of 1.7 million New Zealand citizens.
27 Apr, 2022 | 07:51h | UTCNews Release: Mental disorders may increase risk for subsequent dementia – University of Michigan
Commentary: Mental Disorders Tied to Subsequent Dementia Onset – HealthDay
Commentary on Twitter
In this longitudinal population-register study of 1.7 million New Zealand citizens, individuals with #mentalhealth disorders had elevated risk for #dementia when followed up years later. https://t.co/kkOUOnHEXE
— JAMA Psychiatry (@JAMAPsych) April 15, 2022
New horizons in evidence-based care for older people: individual participant data meta-analysis.
27 Apr, 2022 | 07:50h | UTC
Persistent COVID-19 symptoms in a community study of 606,434 people in England.
26 Apr, 2022 | 08:48h | UTC
Commentary on Twitter
Thirty-eight percent of participants from a community-based study of symptoms following COVID-19 reported persistent symptoms that lasted 12 weeks or more, according to an article published in @NatureComms. https://t.co/sAEutdOkSS pic.twitter.com/oCyyXGIRbk
— Nature Portfolio (@NaturePortfolio) April 20, 2022
Cohort Study: Association of cumulative blood pressure with cognitive decline, dementia, and mortality.
25 Apr, 2022 | 00:35h | UTC
Anticholinergic medications and dementia: should we be worried?
25 Apr, 2022 | 00:14h | UTCCommonly-prescribed drugs and dementia: should we be worried? – Evidently Cochrane
Original Review:
Related:
How well do you know your anticholinergic (antimuscarinic) drugs? – Therapeutics Initiative
Anticholinergic drugs and risk of dementia: case-control study – The BMJ
Commentary on Twitter
Commonly-prescribed drugs & dementia: should we be worried? https://t.co/pvWxT6q48Z A @CochraneUK blog: Jodi Watt (a researcher @UofGlasgow) explores the @CochraneDCIG evidence on whether #anticholinergics might increase people’s risk of future memory problems, or even #dementia
— The Cochrane Library (@CochraneLibrary) April 22, 2022
Cohort Study: Progression to diabetes among older adults with Hemoglobin A1c–defined prediabetes was around 5% after a medium follow up of 2.3 years.
25 Apr, 2022 | 00:01h | UTCCommentaries:
How Often Does Prediabetes in Seniors Escalate to Full-Blown Disease? – MedPage Today (link to abstract – $ for full-text)
New Research Explores Diabetes Progression Rate in Older Adults with Prediabetes – HCP Livre
Related Study: Risk of Progression to Diabetes Among Older Adults With Prediabetes – JAMA Internal Medicine and Commentary: “Prediabetes” Diagnosis Less Useful in Older Patients – Johns Hopkins Bloomberg School of Public Health
Commentary on Twitter
This cohort study found that older adults with prediabetes showed higher progression to diabetes (5.3%) compared to prior studies. https://t.co/cHP7jyV7jT
— JAMA Network Open (@JAMANetworkOpen) April 21, 2022
USPSTF Draft Statement: Postmenopausal women should not use hormone therapy to prevent chronic health problems.
20 Apr, 2022 | 10:15h | UTCDraft Recommendation Statement: Hormone Therapy for the Primary Prevention of Chronic Conditions in Postmenopausal Persons – U.S. Preventive Services Task Force
Commentary: USPSTF Advises Against Hormone Therapy to Prevent Chronic Conditions – HealthDay
An observational study suggests coprescription of Phosphodiesterase Type 5 Inhibitors (i.e., sildenafil) and oral Nitrates is not associated with increased risk of adverse cardiovascular outcomes in male patients with ischemic heart disease.
20 Apr, 2022 | 10:11h | UTCCommentaries:
PDE5 Inhibitors Prescribed for Men on Oral Nitrates for IHD – HealthDay
Retinal age gap as a predictive biomarker of future risk of Parkinson’s disease.
21 Apr, 2022 | 09:54h | UTCRetinal age gap as a predictive biomarker of future risk of Parkinson’s disease – Age and Ageing
Related: Retinal age gap as a predictive biomarker for mortality risk – British Journal of Ophthalmology (link to abstract – $ for full-text)
German guidelines for the diagnosis and treatment of varicose veins.
20 Apr, 2022 | 09:49h | UTCS2k guidelines: diagnosis and treatment of varicose veins – Leitlinien und Empfehlungen


