GI Surgery – Colorectal
M-A: Neoadjuvant therapy vs. direct to surgery for T4 colon cancer.
9 Feb, 2022 | 08:28h | UTCNeoadjuvant therapy versus direct to surgery for T4 colon cancer: meta-analysis – British Journal of Surgery (link to abstract – $ for full-text)
RCT: 2 L polyethylene glycol plus ascorbic acid may provide similar efficacy and better tolerability as 4 L polyethylene glycol for bowel cleansing in elderly patients aged 60–79.
2 Feb, 2022 | 08:29h | UTCComparison of 2 L Polyethylene Glycol Plus Ascorbic Acid and 4 L Polyethylene Glycol in Elderly Patients Aged 60–79: A Prospective Randomized Study – Digestive Diseases and Sciences (link to abstract – $ for full-text)
Related Guidelines:
Bowel preparation before colonoscopy – Gastrointestinal Endoscopy
RCT: In patients undergoing laparoscopic colectomy, intraperitoneal infusion of lidocaine reduced postoperative opioid consumption compared to intravenous infusions of lidocaine.
27 Jan, 2022 | 09:17h | UTCIntravenous Local Anesthetic Compared With Intraperitoneal Local Anesthetic in Laparoscopic Colectomy: A Double-blind Randomized Controlled Trial – Annals of Surgery (link to abstract – $ for full-text)
Review: Genotypic and phenotypic characteristics of hereditary colorectal cancer.
26 Jan, 2022 | 01:16h | UTCGenotypic and Phenotypic Characteristics of Hereditary Colorectal Cancer – Annals of Coloproctology
Review: Treatment for peritoneal metastasis of patients with colorectal cancer.
26 Jan, 2022 | 01:17h | UTCTreatment for Peritoneal Metastasis of Patients With Colorectal Cancer – Annals of Coloproctology
The WSES/SICG/ACOI/SICUT/AcEMC/SIFIPAC guidelines for diagnosis and treatment of acute left colonic diverticulitis in the elderly.
24 Jan, 2022 | 08:24h | UTCRelated:
ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.
Review: Changing paradigms in the management of acute uncomplicated diverticulitis.
Review: Elective surgical management of diverticulitis
State of the Art Review | Management of colonic diverticulitis
Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis
Systematic review: Management of colonic diverticulitis
WSES Guidelines for the Management of Acute Colonic Diverticulitis
ASCRS Guidelines for the Treatment of Left-Sided Colonic Diverticulitis
ACP Guideline: Diagnosis and management of acute left-sided colonic diverticulitis.
18 Jan, 2022 | 09:38h | UTCRelated Systematic Reviews:
Annals Video Summary: Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis: A Systematic Review – Annals of Internal Medicine
News Release: ACP releases two new clinical guidelines on the diagnosis and management of diverticulitis – American College of Physicians
Review: Bowel decontamination before colonic and rectal surgery.
13 Jan, 2022 | 08:36h | UTCBowel decontamination before colonic and rectal surgery – British Journal of Surgery
ASCO Guideline Update: Adjuvant Therapy for Stage II Colon Cancer.
13 Jan, 2022 | 08:19h | UTCAdjuvant Therapy for Stage II Colon Cancer: ASCO Guideline Update – Journal of Clinical Oncology
M-A: Fecal immunochemical test to triage patients with possible colorectal cancer symptoms.
11 Jan, 2022 | 02:18h | UTC
Commentary on Twitter
?#CuttingEdgeBlog Plain English summary?
"Worried about symptoms of bowel cancer? A simple stool test may help."@ian_bissett @SawKS88 @ChenLiu_NZ @williamxu_98 @chrisvarghese98
Blog?: https://t.co/Pb7zfsfWT3
Based on the paper ?: https://t.co/20proTApNd pic.twitter.com/IAUsHIqUrn
— BJS (@BJSurgery) January 10, 2022
Colorectal cancer incidence, mortality, tumor characteristics, and treatment before and after the introduction of the fecal immunochemical testing-based screening program in the Netherlands: a population-based study.
13 Dec, 2021 | 08:50h | UTCColorectal cancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the faecal immunochemical testing-based screening programme in the Netherlands: a population-based study – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Breekveldt et al – #Colorectalcancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the FIT-based #screening programme in the #Netherlands: a population-based studyhttps://t.co/nW9SVAhRxE#GITwitter #crcsm pic.twitter.com/GGRF9Az0tg
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) November 23, 2021
Review: Current treatment and future directions in the management of anal cancer.
1 Dec, 2021 | 08:38h | UTC
Closure of Temporary Ileostomy 2 Versus 12 Weeks After Rectal Resection for Cancer: A Word of Caution from a Prospective, Randomized Controlled Multicenter Trial.
26 Nov, 2021 | 09:42h | UTC
Guideline | Endoscopic tissue sampling – Part 2: Lower gastrointestinal tract.
26 Nov, 2021 | 09:39h | UTC
RCT: Educating outpatients for bowel preparation before colonoscopy using virtual reality videos improved bowel preparation, polyp and adenoma detection rates, and improved compliance and satisfaction.
23 Nov, 2021 | 08:28h | UTC
Commentary on Twitter
RCT finds patients who received virtual reality video education before a colonoscopy had better bowel preparation, higher polyp and adenoma detection rates, and improved compliance and satisfaction. https://t.co/dAUtFf2m4B pic.twitter.com/RKAVZcVGuy
— JAMA Network Open (@JAMANetworkOpen) November 22, 2021
Bowel Perforation: ED presentations, evaluation, and management.
23 Nov, 2021 | 08:19h | UTCBowel Perforation: ED presentations, evaluation, and management – emDocs
Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.
21 Nov, 2021 | 23:01h | UTCRelated:
State of the Art Review: Screening and prevention of colorectal cancer.
USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.
ACG Clinical Guidelines: Start colorectal cancer screening at 45
Long-term results of RCT: Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for patients with locally advanced rectal cancer.
19 Nov, 2021 | 10:15h | UTCChemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer: Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial – JAMA Oncology (free for a limited period)
Author Interview: Chemoradiotherapy Plus Induction or Consolidation Chemotherapy for Locally Advanced Rectal Cancer – JAMA Oncology
Commentary on Twitter
Secondary analysis of 311 pts on ARO-12 trial of variant approaches to total neoadjuvant therapy (TNT) w/combo of chemo & concurrent chemoradiation (CRT) for rectal cancer shows best results w/up-front CRT then chemo & resection led to best results https://t.co/7cpv5cb1Fr #CRCSM pic.twitter.com/bxfz9Fi5OB
— JAMA Oncology (@JAMAOnc) November 18, 2021
RCT: One-time flexible sigmoidoscopy screening is associated with long-term reduction in colorectal cancer incidence and mortality.
10 Nov, 2021 | 07:04h | UTCCommentaries:
A cohort study with 287 patients showed that those who fulfill 5 criteria 2 or 3 days after laparoscopic colorectal surgery (a CRP below 150 mg/dL, a return of bowel function, tolerance of a diet, little pain, and afebrile during the entire stay) have a low risk of developing an anastomotic leak. These criteria have the potential to allow for safe early discharge.
7 Nov, 2021 | 20:06h | UTCAssessing Criteria for a Safe Early Discharge After Laparoscopic Colorectal Surgery – JAMA Surgery (free for a limited period)
Commentary on Twitter
A prospective observational study on 287 adults showing that patients with CRP<150mg/dL, bowel function, diet tolerance, pain<5/10 and no fever, 2-3 days after laparoscopic colorectal surgery have a low anastomotic leak risk and may be discharged early https://t.co/zq8lvHPoQ1
— JAMA Surgery (@JAMASurgery) November 5, 2021
AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract.
27 Oct, 2021 | 01:35h | UTC
M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.
26 Oct, 2021 | 01:42h | UTCStrategies for Antibiotic Administration for Bowel Preparation Among Patients Undergoing Elective Colorectal Surgery: A Network Meta-analysis – JAMA Surgery (free for a limited period)
Commentaries:
Bowel Preparation for Colorectal Surgery: Have All Questions Been Answered? – JAMA Surgery (free for a limited period)
Oral Abx Cut Surgical Site Infections in Colorectal Surgeries — Network meta-analysis finds over 50% SSI reduction with addition of oral to IV antibiotics – MedPage Today (free registration required)
Commentary on Twitter
Network meta-analysis demonstrates that use of oral antibiotics in addition to IV antibiotics greatly reduce the incidence of incisional SSI in elective colorectal surgery https://t.co/pUoWzsmm56
— JAMA Surgery (@JAMASurgery) October 22, 2021
Guidelines for the surgical management of ulcerative colitis.
17 Oct, 2021 | 21:21h | UTC
Commentary on Twitter
@ASCRS_1 Clinical Practice Guidelines – Surgical Management of #UlcerativeColiltis – what do you think? https://t.co/om9IBPoO5S@HolubarStefan @AmyLightnerMD @VitaliyPoylin @JonVogel7 @BradleyDavisMD @UmaMahadevanIBD @DrSamirAShah1 @SunandaKaneMD @ScottRSteeleMD @ianmpaquette pic.twitter.com/D2eywXrATE
— DCRjournal (@DCRjournal) July 9, 2021
RCT: Among patients with metastatic colorectal cancer, those randomized to systemic treatment alone had lower sixty-day mortality compared to those randomized to primary tumor resection followed by systemic treatment.
12 Oct, 2021 | 00:01h | UTCSixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial – JAMA Surgery (free for a limited period)
Editorial: Primary Tumor Resection and Patients With Asymptomatic Colorectal Cancer and Nonresectable Metastases: Results of Recent Randomized Trials – JAMA Surgery (free for a limited period)
Commentary: Systemic Therapy Alone Bests Surgical Tx for Metastatic CRC – BreakingMed
Commentary on Twitter
Early mortality in patients with colorectal cancer and unresectable metastases randomized to primary tumor resection followed by systemic treatment is considerably higher than early mortality in patients randomized to systemic treatment only https://t.co/SyfYjmDU7i @DaveKruijssen
— JAMA Surgery (@JAMASurgery) October 11, 2021
ACG Clinical Guidelines: Management of Benign Anorectal Disorders
10 Oct, 2021 | 21:29h | UTC
Commentary on Twitter
? 2021 ACG Guidelines for Benign Anorectal Disorders ???
?defecation disorders
?proctalgia syndromes
?hemorrhoids
?anal fissures
?fecal incontinence #GITwitter? https://t.co/TeqTWjQkg1 pic.twitter.com/gEfkBsH7kn
— Carl Kay (@CarlKayMD) October 8, 2021