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?#CuttingEdgeBlog Plain English summary?

"Worried about symptoms of bowel cancer? A simple stool test may help."@ian_bissett @SawKS88 @ChenLiu_NZ @williamxu_98 @chrisvarghese98

Blog?: https://t.co/Pb7zfsfWT3

Based on the paper ?: https://t.co/20proTApNd pic.twitter.com/IAUsHIqUrn

— BJS (@BJSurgery) January 10, 2022

Colorectal cancer incidence, mortality, tumor characteristics, and treatment before and after the introduction of the fecal immunochemical testing-based screening program in the Netherlands: a population-based study.

13 Dec, 2021 | 08:50h | UTC

Colorectal cancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the faecal immunochemical testing-based screening programme in the Netherlands: a population-based study – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)

Commentary on Twitter

New research – Breekveldt et al – #Colorectalcancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the FIT-based #screening programme in the #Netherlands: a population-based studyhttps://t.co/nW9SVAhRxE #GITwitter #crcsm pic.twitter.com/GGRF9Az0tg

— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) November 23, 2021

Review: Current treatment and future directions in the management of anal cancer.

1 Dec, 2021 | 08:38h | UTC

Current treatment and future directions in the management of anal cancer – CA: A Cancer Journal for Clinicians

Closure of Temporary Ileostomy 2 Versus 12 Weeks After Rectal Resection for Cancer: A Word of Caution from a Prospective, Randomized Controlled Multicenter Trial.

26 Nov, 2021 | 09:42h | UTC

Closure of Temporary Ileostomy 2 Versus 12 Weeks After Rectal Resection for Cancer: A Word of Caution From a Prospective, Randomized Controlled Multicenter Trial – Diseases of the Colon & Rectum

Guideline | Endoscopic tissue sampling – Part 2: Lower gastrointestinal tract.

26 Nov, 2021 | 09:39h | UTC

Endoscopic tissue sampling – Part 2: Lower gastrointestinal tract. European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Endoscopy

RCT: Educating outpatients for bowel preparation before colonoscopy using virtual reality videos improved bowel preparation, polyp and adenoma detection rates, and improved compliance and satisfaction.

23 Nov, 2021 | 08:28h | UTC

Educating Outpatients for Bowel Preparation Before Colonoscopy Using Conventional Methods vs Virtual Reality Videos Plus Conventional MethodsA Randomized Clinical Trial – JAMA Network Open

Commentary on Twitter

RCT finds patients who received virtual reality video education before a colonoscopy had better bowel preparation, higher polyp and adenoma detection rates, and improved compliance and satisfaction. https://t.co/dAUtFf2m4B pic.twitter.com/RKAVZcVGuy

— JAMA Network Open (@JAMANetworkOpen) November 22, 2021

Bowel Perforation: ED presentations, evaluation, and management.

23 Nov, 2021 | 08:19h | UTC

Bowel Perforation: ED presentations, evaluation, and management – emDocs

Consensus Statement: U.S. Multi-Society Task Force on Colorectal Cancer now suggests average-risk CRC screening begins at age 45.

21 Nov, 2021 | 23:01h | UTC

Updates on Age to Start and Stop Colorectal Cancer Screening: Recommendations From the U.S. Multi-Society Task Force on Colorectal Cancer – Gastroenterology

News release: US Multi-Society Task Force on colorectal cancer releases updated screening recommendations - American Gastroenterological Association

State of the Art Review: Screening and prevention of colorectal cancer.

USPSTF Statement: Start colorectal cancer screening at 45 years for most patients.

ACG Clinical Guidelines: Start colorectal cancer screening at 45

Long-term results of RCT: Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for patients with locally advanced rectal cancer.

19 Nov, 2021 | 10:15h | UTC

Chemoradiotherapy Plus Induction or Consolidation Chemotherapy as Total Neoadjuvant Therapy for Patients With Locally Advanced Rectal Cancer: Long-term Results of the CAO/ARO/AIO-12 Randomized Clinical Trial – JAMA Oncology (free for a limited period)

Author Interview: Chemoradiotherapy Plus Induction or Consolidation Chemotherapy for Locally Advanced Rectal Cancer – JAMA Oncology

Commentary on Twitter

Secondary analysis of 311 pts on ARO-12 trial of variant approaches to total neoadjuvant therapy (TNT) w/combo of chemo & concurrent chemoradiation (CRT) for rectal cancer shows best results w/up-front CRT then chemo & resection led to best results https://t.co/7cpv5cb1Fr #CRCSM pic.twitter.com/bxfz9Fi5OB

— JAMA Oncology (@JAMAOnc) November 18, 2021

RCT: One-time flexible sigmoidoscopy screening is associated with long-term reduction in colorectal cancer incidence and mortality.

10 Nov, 2021 | 07:04h | UTC

Long-Term Follow-up of the Italian Flexible Sigmoidoscopy Screening Trial – Annals of Internal Medicine

Commentaries:

Flexible sigmoidoscopy associated with long-term reduction in colorectal cancer incidence, mortality – ACP Internist

Flexible sigmoidoscopy screening associated with long-term reduction in colorectal cancer incidence and mortality – American College of Physicians

A cohort study with 287 patients showed that those who fulfill 5 criteria 2 or 3 days after laparoscopic colorectal surgery (a CRP below 150 mg/dL, a return of bowel function, tolerance of a diet, little pain, and afebrile during the entire stay) have a low risk of developing an anastomotic leak. These criteria have the potential to allow for safe early discharge.

7 Nov, 2021 | 20:06h | UTC

Assessing Criteria for a Safe Early Discharge After Laparoscopic Colorectal Surgery – JAMA Surgery (free for a limited period)

Commentary on Twitter

A prospective observational study on 287 adults showing that patients with CRP<150mg/dL, bowel function, diet tolerance, pain<5/10 and no fever, 2-3 days after laparoscopic colorectal surgery have a low anastomotic leak risk and may be discharged early https://t.co/zq8lvHPoQ1

— JAMA Surgery (@JAMASurgery) November 5, 2021

AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract.

27 Oct, 2021 | 01:35h | UTC

AGA Clinical Practice Update on Endoscopic Management of Perforations in Gastrointestinal Tract: Expert Review – Clinical Gastroenterology and Hepatology

M-A: Strategies for antibiotic administration for bowel preparation among patients undergoing elective colorectal surgery – “the addition of oral antibiotics to intravenous antibiotics was associated with a reduction in the incidence of incisional surgical site infection by more than 50%”.

26 Oct, 2021 | 01:42h | UTC

Strategies for Antibiotic Administration for Bowel Preparation Among Patients Undergoing Elective Colorectal Surgery: A Network Meta-analysis – JAMA Surgery (free for a limited period)

Commentaries:

Bowel Preparation for Colorectal Surgery: Have All Questions Been Answered? – JAMA Surgery (free for a limited period)

Oral Abx Cut Surgical Site Infections in Colorectal Surgeries — Network meta-analysis finds over 50% SSI reduction with addition of oral to IV antibiotics – MedPage Today (free registration required)

Oral + IV Antibiotics for Bowel Prep Significantly Reduces Surgical Site Infections – Physician’s Weekly

Commentary on Twitter

Network meta-analysis demonstrates that use of oral antibiotics in addition to IV antibiotics greatly reduce the incidence of incisional SSI in elective colorectal surgery https://t.co/pUoWzsmm56

— JAMA Surgery (@JAMASurgery) October 22, 2021

Guidelines for the surgical management of ulcerative colitis.

17 Oct, 2021 | 21:21h | UTC

The American Society of Colon and Rectal Surgeons Clinical Practice Guidelines for the Surgical Management of Ulcerative Colitis – Diseases of the Colon & Rectum

Commentary on Twitter

@ASCRS_1 Clinical Practice Guidelines – Surgical Management of #UlcerativeColiltis – what do you think? https://t.co/om9IBPoO5S @HolubarStefan @AmyLightnerMD @VitaliyPoylin @JonVogel7 @BradleyDavisMD @UmaMahadevanIBD @DrSamirAShah1 @SunandaKaneMD @ScottRSteeleMD @ianmpaquette pic.twitter.com/D2eywXrATE

— DCRjournal (@DCRjournal) July 9, 2021

RCT: Among patients with metastatic colorectal cancer, those randomized to systemic treatment alone had lower sixty-day mortality compared to those randomized to primary tumor resection followed by systemic treatment.

12 Oct, 2021 | 00:01h | UTC

Sixty-Day Mortality of Patients With Metastatic Colorectal Cancer Randomized to Systemic Treatment vs Primary Tumor Resection Followed by Systemic Treatment: The CAIRO4 Phase 3 Randomized Clinical Trial – JAMA Surgery (free for a limited period)

Editorial: Primary Tumor Resection and Patients With Asymptomatic Colorectal Cancer and Nonresectable Metastases: Results of Recent Randomized Trials – JAMA Surgery (free for a limited period)

Commentary: Systemic Therapy Alone Bests Surgical Tx for Metastatic CRC – BreakingMed

Commentary on Twitter

Early mortality in patients with colorectal cancer and unresectable metastases randomized to primary tumor resection followed by systemic treatment is considerably higher than early mortality in patients randomized to systemic treatment only https://t.co/SyfYjmDU7i @DaveKruijssen

— JAMA Surgery (@JAMASurgery) October 11, 2021

ACG Clinical Guidelines: Management of Benign Anorectal Disorders

10 Oct, 2021 | 21:29h | UTC

ACG Clinical Guidelines: Management of Benign Anorectal Disorders – The American Journal of Gastroenterology

Commentary on Twitter

? 2021 ACG Guidelines for Benign Anorectal Disorders ???

?defecation disorders
?proctalgia syndromes
?hemorrhoids
?anal fissures
?fecal incontinence #GITwitter

? https://t.co/TeqTWjQkg1 pic.twitter.com/gEfkBsH7kn

— Carl Kay (@CarlKayMD) October 8, 2021

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