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GI Surgery – Colorectal

RCT: Primary tumor resection plus chemotherapy vs. chemotherapy alone for colorectal cancer patients with asymptomatic, synchronous unresectable metastases

7 Mar, 2021 | 19:23h | UTC

Primary Tumor Resection Plus Chemotherapy Versus Chemotherapy Alone for Colorectal Cancer Patients With Asymptomatic, Synchronous Unresectable Metastases (JCOG1007; iPACS): A Randomized Clinical Trial – Journal of Clinical Oncology

Original study: No Survival Benefit to Primary Resection Before Chemo in Metastatic Colorectal Cancer – Medscape / Reuters

 

 


ACG Clinical Guidelines: Start colorectal cancer screening at 45

5 Mar, 2021 | 08:31h | UTC

ACG Clinical Guidelines: Colorectal Cancer Screening 2021 – The American Journal of Gastroenterology

Related: USPSTF draft statement now recommends starting colorectal cancer screening at 45

 


RCT: Irrigating acetic acid solution during colonoscopy for the detection of sessile serrated neoplasia

4 Mar, 2021 | 08:16h | UTC

Irrigating Acetic Acid Solution During Colonoscopy for the Detection of Sessile Serrated Neoplasia: A Randomized Controlled Trial – Digestive Diseases and Sciences

 


RCT: Laparoscopic anterior resection with or without transanal tube for rectal cancer patients

4 Mar, 2021 | 08:02h | UTC

Laparoscopic anterior resection with or without transanal tube for rectal cancer patients – A multicenter randomized controlled trial – The American Journal of Surgery (link to abstract – $ for full-text)

 


Drains, germs, or steel: Multidisciplinary management of acute colonic diverticulitis

26 Feb, 2021 | 08:17h | UTC

Drains, Germs, or Steel: Multidisciplinary Management of Acute Colonic Diverticulitis – Digestive Diseases and Sciences

 


Review: Diagnosis and treatment of metastatic colorectal cancer

19 Feb, 2021 | 02:07h | UTC

Diagnosis and Treatment of Metastatic Colorectal Cancer: A Review – JAMA (free for a limited period)

 


M-A: Role of diet in colorectal cancer incidence

17 Feb, 2021 | 01:12h | UTC

Role of Diet in Colorectal Cancer Incidence: Umbrella Review of Meta-analyses of Prospective Observational Studies – JAMA Network Open

 


RCT: Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer

16 Feb, 2021 | 01:44h | UTC

Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer (RELARC): a randomised, controlled, phase 3, superiority trial – The Lancet Oncology (link to abstract – $ for full-text)

 


Duration of adjuvant doublet chemotherapy (3 or 6 months) in patients with high-risk stage II colorectal cancer

3 Feb, 2021 | 01:10h | UTC

Duration of Adjuvant Doublet Chemotherapy (3 or 6 months) in Patients With High-Risk Stage II Colorectal Cancer – Journal of Clinical Oncology

Commentary: Adjuvant Doublet Chemotherapy for High-Risk Stage II Colorectal Cancer: 3- or 6- Month Duration? – The ASCO Post

 


Meta-analysis: Risk of colorectal cancer and cancer related mortality after detection of low-risk or high-risk adenomas, compared with no adenoma, at index colonoscopy

3 Feb, 2021 | 01:20h | UTC

Risk of Colorectal Cancer and Cancer Related Mortality After Detection of Low-risk or High-risk Adenomas, Compared With No Adenoma, at Index Colonoscopy: A Systematic Review And Meta-Analysis – Gastroenterology (link to abstract – $ for full-text)

Related studies: Colorectal Cancer Incidence and Mortality After Removal of Adenomas During Screening Colonoscopies – Gastroenterology AND Long-term Risk of Colorectal Cancer and Related Death After Adenoma Removal in a Large, Community-based Population – Gastroenterology (link to abstract – $ for full-text) AND Baseline Colonoscopy Findings Associated with 10-Year Outcomes in a Screening Cohort Undergoing Colonoscopy Surveillance – Gastroenterology (link to abstract – $ for full-text) AND Association of Colonoscopy Adenoma Findings With Long-term Colorectal Cancer Incidence – JAMA

Related guideline: Recommendations for Follow-Up After Colonoscopy and Polypectomy: A Consensus Update by the US Multi-Society Task Force on Colorectal Cancer – Gastroenterology

 


Cohort study: Aspirin linked to reduced risk of colon cancer if you start it before age 70

26 Jan, 2021 | 00:37h | UTC

Aspirin Use and Risk of Colorectal Cancer Among Older Adults – JAMA Oncology (free for a limited period)

Commentaries: Does aspirin lower colorectal cancer risk in older adults? It depends on when they start – Massachusetts General Hospital AND Aspirin Use Cuts CRC Risk in Those Initiating Use Before Age 70 – Physician’s Weekly

 


Postsurgical disease recurrence in stage I to III colorectal cancer may be predicted by ctDNA

20 Jan, 2021 | 01:07h | UTC

Abstract: Circulating tumor DNA analysis for assessment of recurrence risk, benefit of adjuvant therapy, and early relapse detection after treatment in colorectal cancer patients – ASCO Meeting Library

Commentaries: Postsurgical Disease Recurrence in Stage I to III Colorectal Cancer May Be Predicted by ctDNA – The ASCO Post AND Liquid Biopsy Predicts Colon Cancer Relapse Months Before CT – MedPage Today (free registration required)

 


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