Gastroenterology (all articles)
RCT | Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn’s disease on combination therapy
17 Jan, 2023 | 13:10h | UTCInvited commentary: Treatment withdrawal in Crohn’s disease: slowly becoming clearer – The Lancet Gastroenterology & Hepatology (free registration required)
Commentary on Twitter
New research – Louis et al – Withdrawal of infliximab or concomitant immunosuppressant therapy in patients with Crohn’s disease on combination therapy (SPARE): a multicentre, open-label, randomised controlled trialhttps://t.co/T40BmgHtem#IBD #GITwitter #medtwitter pic.twitter.com/iOIbi0WowU
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) January 12, 2023
Review | Liver intensive care for the general intensivist
17 Jan, 2023 | 12:59h | UTCLiver intensive care for the general intensivist – Anaesthesia
Development and validation of a prognostic nomogram for older patients with acute-on-chronic liver diseases
15 Jan, 2023 | 19:46h | UTCSee also: dynamic nomogram
Cohort Study | Antibiotic exposure linked to increased risk of inflammatory bowel disease
13 Jan, 2023 | 13:25h | UTCNews Release: Frequent use of antibiotics may heighten inflammatory bowel disease risk in over 40s – BMJ Newsroom
Commentaries:
Antibiotics may increase risk of inflammatory bowel disease, study finds – CIDRAP
Antibiotic Exposure Positively Linked to IBD Development – HealthDay
Commentary on Twitter
#GUTPressRelease on the paper by @AdamFayeMD, @KristineAllin, @manasiagrawalmd, @PREDICTIBD et al
"Antibiotic use as a risk factor for inflammatory bowel disease across the ages: a population-based cohort study" viahttps://t.co/zc9bG3CpSm#GUTInTheNews pic.twitter.com/xra8wfEgnr
— Gut Journal (@Gut_BMJ) January 9, 2023
Review | The pathogenesis and therapeutic strategies of heat stroke-induced liver injury
13 Jan, 2023 | 13:07h | UTCThe pathogenesis and therapeutic strategies of heat stroke-induced liver injury – Critical Care
RCT | Second-line levofloxacin-based quadruple therapy vs. bismuth-based quadruple therapy for Helicobacter pylori eradication
12 Jan, 2023 | 13:06h | UTCSecond-line levofloxacin-based quadruple therapy versus bismuth-based quadruple therapy for Helicobacter pylori eradication and long-term changes to the gut microbiota and antibiotic resistome: a multicentre, open-label, randomised controlled trial – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Liou et al – Second-line levofloxacin-based quadruple therapy vs bismuth-based quadruple therapy for H pylori eradication and long-term changes to the gut #microbiota and antibiotic resistome: an RCThttps://t.co/Aipu3TRyFr#Hpylori #microbiome #AMR @emadelomar pic.twitter.com/aeFMAI3FCj
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 20, 2022
M-A | Blood endotoxin levels as biomarker of non-alcoholic fatty liver disease
12 Jan, 2023 | 12:57h | UTC
Review | Early diagnosis and prevention of infections in cirrhosis
12 Jan, 2023 | 12:47h | UTCEarly Diagnosis and Prevention of Infections in Cirrhosis – Seminars in Liver Disease
RCT | Dupilumab in adults and adolescents with eosinophilic esophagitis
11 Jan, 2023 | 14:27h | UTCDupilumab in Adults and Adolescents with Eosinophilic Esophagitis – New England Journal of Medicine (link to abstract – $ for full-text)
Commentary: Weekly Dupilumab Beneficial in Eosinophilic Esophagitis – HealthDay
M-A | Dietary interventions for the treatment of inflammatory bowel diseases
11 Jan, 2023 | 13:54h | UTC
RCT | The addition of Olanzapine to a triple antiemetic regimen effectively prevents nausea and vomiting during highly emetogenic chemotherapy.
16 Dec, 2022 | 13:32h | UTCRelated:
Phase 1b/2a Study | Safety, pharmacokinetics, and pharmacodynamics of Pegozafermin in patients with non-alcoholic steatohepatitis.
16 Dec, 2022 | 13:29h | UTCSafety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a multiple-ascending-dose study – The Lancet Gastroenterology & Hepatology (link to abstract – $ for full-text)
Commentary on Twitter
New research – Loomba et al – Safety, pharmacokinetics, and pharmacodynamics of pegozafermin in patients with non-alcoholic steatohepatitis: a randomised, double-blind, placebo-controlled, phase 1b/2a study https://t.co/49u1OQKSRJ#livertwitter #NASH #fattyliver @DrLoomba pic.twitter.com/2emqc8Qkfw
— The Lancet Gastroenterology & Hepatology (@LancetGastroHep) December 13, 2022
RCT | Hypophosphataemia following ferric derisomaltose vs. ferric carboxymaltose in patients with iron deficiency anemia due to IBD.
16 Dec, 2022 | 13:15h | UTC
Polled analysis of RCTs | Linaclotide reduced response time for irritable bowel syndrome with constipation symptoms.
16 Dec, 2022 | 13:17h | UTC
A comprehensive systematic review of colorectal cancer screening clinical practices guidelines and consensus statements.
16 Dec, 2022 | 13:09h | UTC
SR | Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins.
14 Dec, 2022 | 14:51h | UTCTreatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins – Cochrane Library
Review | Interventional gastroenterology in oncology.
12 Dec, 2022 | 12:46h | UTCInterventional gastroenterology in oncology – CA: A Cancer Journal for Clinicians
UEG position paper | Obesity and digestive health.
12 Dec, 2022 | 12:41h | UTCUEG position paper: Obesity and digestive health – UEG Journal
Brief Review | Diagnosis and management of gastroparesis.
12 Dec, 2022 | 12:35h | UTCDiagnosis and Management of Gastroparesis – The American Journal of Gastroenterology
Related:
Worldwide prevalence and burden of gastroparesis-like symptoms.
ACG Clinical Guideline: Gastroparesis – The American Journal of Gastroenterology
German guideline on diverticular disease/diverticulitis. Part II – Conservative, interventional and surgical management.
8 Dec, 2022 | 12:55h | UTCRelated:
Systematic Review: Antibiotics for uncomplicated diverticulitis.
Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)
Elective surgical management of diverticulitis – Current Problems in Surgery
Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality
Guideline Summary | Evaluation and management of gastroesophageal reflux disease.
5 Dec, 2022 | 00:18h | UTCOriginal Guideline: ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease – American Journal of Gastroenterology
Related Guidelines:
ACG Clinical Guideline for the Diagnosis and Management of Gastroesophageal Reflux Disease.
SAGES guidelines for the surgical treatment of gastroesophageal reflux.
Guideline on Screening for Esophageal Adenocarcinoma in Patients with Chronic GERD
NICE Guideline: Gastro-esophageal Reflux Disease and Dyspepsia in Adults
NICE Guideline: Gastroesophageal Reflux Disease in Children and Young People
Review | Management of acute kidney injury in patients with cirrhosis.
5 Dec, 2022 | 00:11h | UTCManagement of AKI in Patients with Cirrhosis – Current Treatment Options in Gastroenterology
RCT | Rivaroxaban prophylaxis in noncirrhotic portal vein thrombosis.
2 Dec, 2022 | 14:24h | UTCRivaroxaban Prophylaxis in Noncirrhotic Portal Vein Thrombosis – NEJM Evidence
Commentary on Twitter
This #RCT examined the use of rivaroxaban to reduce risk of venous thromboembolism (VTE) in pts with non-cirrhotic chronic portal vein thrombosis (PVT). Daily rivaroxaban reduced incidence of VTE and did not increase major bleeding events. https://t.co/CbenUb8ZWz#LiverTwitter pic.twitter.com/bgN1QS171j
— NEJM Evidence (@NEJMEvidence) November 22, 2022
Review | Acute and chronic alcoholic pancreatitis, including paraduodenal pancreatitis.
2 Dec, 2022 | 14:08h | UTC
German guideline on diverticular disease/diverticulitis.
30 Nov, 2022 | 13:41h | UTCEditorial: New German guidelines for the management of diverticulitis – UEG Journal
Related:
Systematic Review: Antibiotics for uncomplicated diverticulitis.
Efficacy and Safety of Non-Antibiotic Outpatient Treatment in Mild Acute Diverticulitis (DINAMO-study): A Multicentre, Randomised, Open-Label, Non-Inferiority Trial – Annals of Surgery (link to abstract – $ for full-text)
Elective surgical management of diverticulitis – Current Problems in Surgery
Management of Colonic Diverticulitis – Agency for Healthcare Research and Quality